RYDE-WORK/lnp_ml
1
0
Fork 0
mirror of https://github.com/RYDE-WORK/lnp_ml.git synced 2026-03-21 09:36:32 +08:00
Code Issues Packages Projects Releases Wiki Activity

Merge branch 'main' of github.com:RYDE-WORK/lnp_ml

Browse Source
This commit is contained in:
RYDE-WORK 2026-03-03 10:42:03 +08:00
commit 4b75b7406d
102 changed files with 4005 additions and 6536 deletions
Show Stats Download Patch File Download Diff File Expand all files Collapse all files

840
data/interim/internal.csv
View File

@ -1,421 +1,421 @@
smiles,Helper_lipid_ID,Helper_lipid_ID_DOPE,Helper_lipid_ID_DOTAP,Helper_lipid_ID_DSPC,Helper_lipid_ID_MDOA,Cationic_Lipid_to_mRNA_weight_ratio,Cationic_Lipid_Mol_Ratio,Phospholipid_Mol_Ratio,Cholesterol_Mol_Ratio,PEG_Lipid_Mol_Ratio,Purity,Mix_type,Cargo_type,Cargo_type_mRNA,Cargo_type_pDNA,Cargo_type_siRNA,Target_or_delivered_gene,Model_type,Model_type_A549,Model_type_BDMC,Model_type_BMDM,Model_type_HBEC_ALI,Model_type_HEK293T,Model_type_HeLa,Model_type_IGROV1,Model_type_Mouse,Model_type_RAW264p7,Delivery_target,Delivery_target_body,Delivery_target_dendritic_cell,Delivery_target_generic_cell,Delivery_target_liver,Delivery_target_lung,Delivery_target_lung_epithelium,Delivery_target_macrophage,Delivery_target_muscle,Delivery_target_spleen,Route_of_administration,Route_of_administration_in_vitro,Route_of_administration_intramuscular,Route_of_administration_intratracheal,Route_of_administration_intravenous,Batch_or_individual_or_barcoded,Batch_or_individual_or_barcoded_Barcoded,Batch_or_individual_or_barcoded_Individual,Value_name,Formulation_ID,Cationic_Lipid_Mass_Ratio,Phospholipid_Mass_Ratio,Cholesterol_Mass_Ratio,PEG_Lipid_Mass_Ratio,Amine,Tail,Lipid_name,Library_ID,Experiment_ID,Experimenter_ID,Experiment_weight,Goal,screen_id,Source,Sample_weight,Comment,Amine_number,Full_SMILES,Amine_SMILES,Tail_length,Num_tails,Ketone,Isocyanide,Is_cyclic,Formulation,Batch_or_individual,Random_id,4CR_Lipid_name,Aldehyde,Carboxylic_acid,Amine_name,Tail_name,Linker,MolWt,Tail_count,Num tails,Common_name,Ester,Disulfide,Total_radiance,Form_comment,molecular_weight,split_name_for_normalization,Encapsulation_Efficiency_EE<50,Encapsulation_Efficiency_50<=EE<80,Encapsulation_Efficiency_80<EE<=100,PDI_0_0to0_2,PDI_0_2to0_3,PDI_0_3to0_4,PDI_0_4to0_5,toxic,size,Biodistribution_lymph_nodes,Biodistribution_heart,Biodistribution_liver,Biodistribution_spleen,Biodistribution_lung,Biodistribution_kidney,Biodistribution_muscle,quantified_total_luminescence,unnormalized_delivery,quantified_delivery
O=C(CN(CCCCCCCCCCCC)CCCCCCCCCCCC)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.44559484,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.892641641172089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCCCC,DSPC,0,0,1,0,15.24245185,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.345103280569283,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.310127759130018,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,16.95535314,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.35696520407851,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCC)CCCCCCCCCC)NCCCN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.51030189,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.175309921045206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.11860943,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.447697327163527,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,16.80841018,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.381651564343798,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,14.7769988,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.250350662548819,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.386765389021055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.55151343,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.391729410135267,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.85660447,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.114394528387108,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.63293083,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,5.272999558563747,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O,DSPC,0,0,1,0,16.2856483,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.28978103552575,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)NCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.23582504,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.260615499364025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)CN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.75702627,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9788005705762375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.47477668,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.68213122712422,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,19.33366115,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.98780245,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9473404437239425,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CO)=O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.42695266,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.545101659521972,0.0,0.00318490682025255,0.0608074236431031,0.251089505980848,0.00892095913117615,0.00601048706680474,0.669986717357815,0.0815243428420059,0.0815243428420059,-0.9228588036953479
CCCCCCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)=O)CO)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.68206611,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.844974178195408,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H]([C@H](O)C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.77114057,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,thr,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.331522502500114,0.0,0.0131160505661734,0.0817206877958181,0.209957462105326,0.0363069917919837,0.0161572104727098,0.642741597267989,0.0248953087459781,0.0248953087459781,-1.0036817494221935
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4135253017332525,0.0,0.00151329913495755,0.0471551068594211,0.0476760649180962,0.00182335320536251,0.00763287581452213,0.89419930006764,0.35502103370942,0.35502103370942,-0.5325147239258616
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.509649984130679,0.0,0.00235961766437825,0.513627015742916,0.0879412499947796,0.00175822838354556,0.00311254749811917,0.391201340716262,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.496359280129911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC,DSPC,0,0,1,0,14.13296737,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.170425586627436,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.445353484534206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,15.1299087,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.166510173022286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.673109168996284,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.72728505,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.7572902340489245,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.000230328920605394,0.0259372790881254,0.0734981485145439,0.000576894596302152,0.000867946038939987,0.898889402841483,0.486446282346577,0.486446282346577,-0.34493999468492637
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.00183814880222334,0.508470854676458,0.479298868566087,0.00664368457868438,0.00374844337654761,0.0,0.0806697533656258,0.0806697533656258,-0.5836902104683951
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,14.7050121,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.00446051681777838,0.0286140231457339,0.01484311836534,0.00629790100652696,0.01599114503205,0.929793295632571,0.0275210452544693,0.0275210452544693,-0.9999342060867568
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.7050121,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.0104002218216073,0.139229779861971,0.807246421461676,0.041233674188,0.00188990266674509,0.0,0.0040656278842911,0.0040656278842911,-0.7881076899433005
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.00711911642710361,0.153280595121264,0.136743424441396,0.0628412485834964,0.0734141937722642,0.566601421654476,0.0027486514420013,0.0027486514420013,-1.0352902363032352
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.106975953776871,0.247623902989694,0.292657465739291,0.229416263063982,0.123326414430162,0.0,0.001042320755636,0.001042320755636,-0.7961753601769197
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.789157022101107,0.0,0.0386975655052687,0.153034034478582,0.0799184464451532,0.0414429326981307,0.0607210626185958,0.626185958254269,0.0073827728841294,0.0073827728841294,-1.0286762554754216
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,1,0,0,0,0.0,4.639571612705423,0.0,0.135531713474282,0.541180183023036,0.178510571158094,0.0949195329757021,0.0498579993688861,0.0,0.004009461265808,0.004009461265808,-0.7882575701032632
O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,15.91058453,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.639571612705423,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.000231298468169262,0.195828728849491,0.0126185833117857,0.000504922171493209,0.00109315352063243,0.789723313678428,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.00515447939315304,0.962574355010024,0.0304157301451643,0.000918038843316605,0.000937396608342438,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0963955724315343,0.000259669027359828,0.0209585518067849,0.0324510369422159,0.00191021824445882,0.00526970020363582,0.84275525134401,0.95415067884307,0.95415067884307,0.32258414125816925
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0,0.00301852406237983,0.561715155652109,0.427466534539213,0.00675382930885143,0.00104595643744612,0.0,0.469108231863161,0.469108231863161,0.4528546780295592
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.424367475163407,0.00431198097235812,0.000818950238891083,0.0696322838846972,0.0220758004851341,0.00177157151502323,0.00255208415951453,0.898837328744382,0.673380628639453,0.673380628639453,-0.07814073232611048
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.424367475163407,0.0,0.00336772556852765,0.856457049453334,0.133858740361315,0.00483749939645135,0.00147898522037143,0.0,0.274077344076178,0.274077344076178,-0.06758364367522034
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0465123735855303,0.000498926332937811,0.165458883776434,0.0565565738614754,0.00106294680997165,0.00247840641808945,0.727431889215561,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0,0.00167236193574396,0.848665421605967,0.144098339320739,0.00370843762360476,0.00185543951394526,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0297656858896609,0.000244336475601744,0.00951547807887942,0.00817695885320599,0.000472306069630483,0.00458791238707824,0.947237322245943,0.549425262386022,0.549425262386022,-0.2550541831588352
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0,0.00411439872497652,0.670601694270008,0.311096989874152,0.00850379747404768,0.00568311965681539,0.0,0.0620258136097327,0.0620258136097327,-0.6334414105302022
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.311727053457954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.00523681863830338,0.000823668079767528,0.00977318183991921,0.0124596675509096,0.00267973433328739,0.00363617950788083,0.965390750049932,0.316498770359056,0.316498770359056,-0.5874950507095055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.0,0.010109099822305,0.45796731805265,0.507501663530466,0.0194068402228631,0.00501507837171616,0.0,0.0817828774610745,0.0817828774610745,-0.5807198479650095
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.590361070334383,0.00631834763893091,0.000504819647616299,0.140779687268235,0.0297514168337676,0.000617892126006545,0.0011394500617625,0.820888386423681,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.590361070334383,0.0,0.00283873189227405,0.901276452952094,0.0938738308613158,0.00141019974741145,0.000600784546904834,0.0,1.0,1.0,1.8695349995476385
O=C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)[C@H](C)N(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.63651378,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.442651256490317,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.530769863411841,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)CN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.88045619,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.48874872297084,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)CN(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.83327693,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.343844382133684,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.53889564,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.301494223781961,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0159262664008309,0.00726471746994425,0.0644691443511897,0.0154248397225439,0.00666778094817397,0.00618426236554005,0.884062988741777,0.163983867672707,0.163983867672707,-0.8051696746745034
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0,0.0110768066820314,0.679238145596264,0.289982439081482,0.0151104362851107,0.00459217235511197,0.0,0.0864824917721372,0.0864824917721372,-0.5681789657875123
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.285378059618076,0.00952025723585679,0.00424787112198889,0.0270494802958792,0.00951147065788185,0.00569809581675416,0.00864159943836194,0.935331225433277,0.22281247574214,0.22281247574214,-0.7212074197450102
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.285378059618076,0.0,0.00577401787332259,0.781123329740865,0.202386288853494,0.00852464019685452,0.00219172333546338,0.0,0.23688698835255,0.23688698835255,-0.16682580237138014
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0307690543253117,0.000803846893528031,0.00327375890943859,0.00440309874760962,0.00131506681420977,0.00341198428561488,0.956023190024287,1.14370500641117,1.14370500641117,0.5931227328814345
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0,0.0103006057269574,0.229208194092422,0.735779643429865,0.0182228400970524,0.00648871665370264,0.0,0.146101132843469,0.146101132843469,-0.40908711190961344
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.573885895948325,0.00305704097815131,0.00100491779320209,0.0165773259574103,0.0117710271412967,0.00208697129856503,0.00287252217431477,0.96263019465706,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.573885895948325,0.0,0.00330040832612047,0.545398801975274,0.446192251044312,0.00323782528214899,0.00187071337214386,0.0,1.0,1.0,1.8695349995476385
O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.79756457,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.789042318607025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.40770989,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.168208681201016,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.93089479,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.697749367281185,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.38737682,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.2112383136936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.27999390910873,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.611152257665639,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.1422481808981475,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.515354881665727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.57532934397707,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.451896454476337,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.925077405734609,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.829912458665998,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421728001525434,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.775756486563625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.862341963516347,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.55042057,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,5.5506312951620265,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.34229222,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.47597224751641,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.30473405,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.563722996073918,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O,DSPC,0,0,1,0,16.11614863,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.275554390163365,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O,DSPC,0,0,1,0,16.80938411,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.35709336812867,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.32727581,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.473579765600494,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,17.03239796,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.5612182984589085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.71577453,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.695924549256556,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.72351388,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.857484114602081,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.6246954,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.483228515182849,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O,DSPC,0,0,1,0,16.38850868,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.426521874560433,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O,DSPC,0,0,1,0,17.04402965,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.412919498116252,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.53558149,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.69866052907543,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.95535314,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.9459189793765646,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.450269224770129,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.46731585,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.659658371272161,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.8769168,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.139321635057579,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.04309994,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.283448621312786,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O,DSPC,0,0,1,0,17.76093253,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1455128487965,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,18.07661492,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.3551691805039985,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.632923618509176,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-],DSPC,0,0,1,0,12.69438691,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TEA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.762173934797756,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0111914004572023,0.00227125491616379,0.00877931935589419,0.0082437061808303,0.00401873844514775,0.00849693826019724,0.956998642384564,0.596141429580998,0.596141429580998,-0.18837922911736
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0,0.00531733106486159,0.69156525750989,0.28508003495893,0.0160312488066627,0.00200612765965623,0.0,0.176602424488684,0.176602424488684,-0.3276946657499996
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0210584248832937,0.000931640117614886,0.0300315170504259,0.0160360600660287,0.002060495753182,0.00519348457253804,0.924688377556917,0.507741968135695,0.507741968135695,-0.31454604422779553
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0,0.00533934786984105,0.597844801683409,0.374278985337898,0.0199301473078145,0.00260671780103763,0.0,0.177860137006811,0.177860137006811,-0.3243384702286213
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.664405571096625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.498141613229568,0.00224222740615835,0.000962422246665562,0.00287219892799367,0.00322451176864607,0.00206661890626862,0.00333409585594076,0.985297924888327,0.792858557060483,0.792858557060483,0.0923823620278189
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.498141613229568,0.0,0.00657230701947091,0.556297397905001,0.404138164228711,0.0296624454205942,0.00332968542622302,0.0,0.20948041157182,0.20948041157182,-0.2399600273409918
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.462799844696365,0.0122002332749747,0.000591091003585345,0.00113975593374826,0.00176766182040017,0.00118628775621157,0.000814512180559894,0.98230045803052,1.58712844716331,1.58712844716331,1.2259922362734261
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.462799844696365,0.0,0.0055909076747788,0.864547542326111,0.121503978921508,0.00729914012568763,0.00105843095191469,0.0,0.762385942529413,0.762385942529413,1.2354638394013375
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0390763854278316,0.00164994009844252,0.0661192424915616,0.0206209930549816,0.00197347693054232,0.00160454285244798,0.868955419144192,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0,0.00384316363496011,0.851255867494199,0.137210400166604,0.00701109092659647,0.000679477777641109,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.67788651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.401951803481151,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCCC)OCCCCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)CO)=O,DSPC,0,0,1,0,17.86915095,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421487703554795,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O,DSPC,0,0,1,0,17.61285873,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.577593418217857,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCCC(OCCCCCCCCC)=O,DSPC,0,0,1,0,15.66191374,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DBU,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.647271362006727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.541058240520847,0.0155523974922323,0.00129152518305059,0.446962380102849,0.0407067099579296,0.00170625578284345,0.00421830607343662,0.489562425407659,1.0,4.04718291807415,4.73706835052163
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.83323084,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.1751562049585145,0.127270779777207,0.0355651632001246,0.0965373529640882,0.0454740204097531,0.0338026797538366,0.0465840928565864,0.614765911038405,0.0505010966098528,0.0505010966098528,-0.9671362699547936
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.95682792,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.416186486320586,0.0275897803818406,0.0140220813902507,0.0611423332934752,0.0248626002542061,0.0133347505104052,0.0187510241318683,0.840297430037954,0.11103838626238,0.11103838626238,-0.8807353246775064
C=CCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)=O,DSPC,0,0,1,0,18.01719192,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.445588116163626,0.0250376334304389,0.00337885545037859,0.0517009582142691,0.0430146012578083,0.00350252056656834,0.00406753936383155,0.869297891716705,0.594087846809013,0.594087846809013,-0.19131017455153912
CCCCCCCCCCCC(OCCCCCCN(CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.28161356,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.381026134340298,0.00774884428490629,0.00205921183588078,0.0366644403250292,0.0113925424121347,0.00225130046176364,0.00414541402825956,0.935738246652026,0.903691788703443,0.903691788703443,0.2505674416217897
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.382151626862033,0.0281381236661192,0.00268792352252722,0.218417144486954,0.0369503427520482,0.00199553488006137,0.00289937744032574,0.708911553251965,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.83044719,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.199605072879594,0.0747106900577881,0.0465999615731367,0.107994265529626,0.0501322770872438,0.0448116344718523,0.0485065251769853,0.627244646103368,0.0685266977729659,0.0685266977729659,-0.9414094990897005
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.94795095,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.333755086000182,0.0109650973341036,0.00500301836333305,0.0209516607489436,0.00928876974106986,0.00498354505150691,0.00613733877720584,0.942670569983837,0.624112412102086,0.624112412102086,-0.14845806079238213
CCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.64728116,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.333098961050458,0.0312031939311219,0.00665572714585857,0.0303955096845431,0.016483404133503,0.00703656560389733,0.0108270584446455,0.897398541056431,0.396247798437663,0.396247798437663,-0.4736744378197291
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.21401022,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,0.0,4.865224091322398,0.113993758795815,0.073640090558649,0.155999510493789,0.089181912745518,0.0778008933488344,0.0854800220277795,0.403903812029615,0.0331042054271613,0.0331042054271613,-0.991965723861604
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.964966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.177279038170981,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.327834405590455,0.0791681309989092,0.00438236238399703,0.207450725009039,0.0200057324176319,0.00435501692886232,0.00687586277442937,0.677762169487131,1.0,1.0,0.38802190219888055
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.01143435,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.826712455935327,0.051854991416453,0.0528002488161413,0.131177333337399,0.0608349367134925,0.0676316423389937,0.091080124286102,0.544620723091419,0.0058976768275302,0.0058976768275302,-1.0307958367096368
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.98131005,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.613138355637268,0.0349404656939791,0.032170759570341,0.107989787547248,0.0410644871922655,0.0376181677387698,0.0487295770112475,0.697486755246149,0.0093821747742871,0.0093821747742871,-1.025822638898096
O=C([C@H](CO)N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,13.72220648,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.45318382899021,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.27012616,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.256453162449338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.19898065,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.86830338551846,0.0353281775739917,0.00307182736960491,0.034716407488313,0.0124183147896963,0.00493000176115631,0.00714349716206655,0.902391773855171,0.291015633780908,0.291015633780908,-0.6238654779555869
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.260282639765531,0.0263012913083446,0.00104221918552839,0.17396331575752,0.0231252484593015,0.00218421226891195,0.00250493797184971,0.770878775048544,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.400848388914469,0.142104027989206,0.00287714799265922,0.215134204863943,0.0243152184566193,0.00619704480449007,0.00405451457231669,0.605317841320765,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN(CCN(C)CCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.06597416,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3551691805039985,0.0696417285874694,0.0029599268608454,0.0569405498935433,0.0189535946790038,0.00628554949471398,0.00620455647115851,0.839014094013266,1.46543205325214,1.46543205325214,1.0523028700808776
O=C(OCCCCCCN([C@H](C(NCCN(C)CCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.80021894,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.318154558079471,0.0260251149767627,0.00751090805185066,0.0532899531021804,0.0511794000344704,0.0152455710134586,0.0158624088727893,0.830886643948488,0.594741863231617,0.594741863231617,-0.19037673935045565
CCCCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)=O,DSPC,0,0,1,0,17.89376817,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.605170185988092,0.00991904799330563,0.00800736011391533,0.0452217049389508,0.0197202047147262,0.0164331186633441,0.0158205463682553,0.884878017207502,0.0777961107519447,0.0777961107519447,-0.9281798674338029
O=C(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.61561565,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.886582645426277,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN(CCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.01340623,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.190175207928333,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCOCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.7439276,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2694176902912275,0.0273933363293668,0.0025481137083807,0.0489889660247262,0.00910395259986531,0.00553863037137659,0.00570731639004281,0.900719684576242,0.282511511559215,0.282511511559215,-0.6360028597730629
O=C(CCCCCCCCCCC)OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.18802872,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.561949483533528,0.0107761878140537,0.0018907931479914,0.00906874325536026,0.00817364202148832,0.00369121050409089,0.00412231341943734,0.962277109837578,1.03869430459932,1.03869430459932,0.44324777229346224
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.8896653,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.422808628394115,0.0,0.00393259539867672,0.698404256940233,0.29082082024119,0.00482745799593445,0.00201486942396601,0.0,0.150267764477171,0.150267764477171,-0.3979684896277195
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.24735173134728,0.0,0.0193985055782088,0.642311593152982,0.297952931923085,0.0232690994142363,0.0170678699314884,0.0,0.0138284395356039,0.0138284395356039,-0.7620557072620823
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.776599301615622,0.0,0.00374237304524464,0.388696129733584,0.542462789676973,0.0600826887673663,0.00501601877683173,0.0,0.0757788640374704,0.0757788640374704,-0.5967415084575073
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.59784341060163,0.0,0.00454633850545055,0.547957057084188,0.42844914578143,0.0150324705651762,0.00401498806375593,0.0,0.0747683143174281,0.0747683143174281,-0.5994381520828621
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,0.465,0.075,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.784988612563928,0.0,0.00648649184357099,0.353238786148937,0.611732175774514,0.0204133713900616,0.00812917484291689,0.0,0.231046253558505,0.231046253558505,-0.18241175518238087
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.684905154006945,0.0,0.00209231248329155,0.858334702447977,0.133879376324869,0.0038743559198132,0.0018192528240494,0.0,1.0,1.0,1.8695349995476385
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)C,DSPC,0,0,1,0,18.00540724,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.583231278469338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)C,DSPC,0,0,1,0,17.73535311,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.224056168743758,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCC(OCCCCCCN(CCCNC([C@@H](N(CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CO)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)=O)OCCCC(F)(F)F,DSPC,0,0,1,0,18.72527826,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.972587226458726,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.8896653,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.363226005210164,0.0302618004269707,0.0170318389360463,0.0852511261606349,0.0321310738618372,0.020553836096385,0.0249767617646758,0.78979356275345,0.103578477209434,0.103578477209434,-0.8913823687978608
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,17.93964861,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.27430221608671,0.0441668582339066,0.00173504332049564,0.0552287456296669,0.0103338721124601,0.00424436496446174,0.00798306414101548,0.876308051597994,0.118006736161235,0.118006736161235,-0.8707898510406828
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.66483929,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.322011202263895,0.014374943627672,0.00199135248489222,0.0891563599260395,0.0109943655858212,0.00408170887074953,0.00721565797781185,0.872185611527014,0.120117219447052,0.120117219447052,-0.867777695195366
C=CCCCCCCCCC(OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.93091393,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.589955020181611,0.159505299591344,0.00863892692709962,0.059163494819016,0.0251436766117119,0.0207012928199433,0.0319161553971728,0.694931153833713,0.19624671777719,0.19624671777719,-0.7591230022455473
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.461068842013835,0.18227458966528,0.00260059752378256,0.10140002712747,0.0194272464327483,0.00394998811850684,0.00708234329707097,0.683265207835141,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.897839799950911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87291972,0.3296703297,0.2197802198,0.4395604396,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.667205576907544,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.34369997,0.41322314050000003,0.16528925619999998,0.41322314050000003,0.00826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.786658062033468,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.12329906,0.2702702703,0.32432432429999997,0.3783783784,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.520374534283375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.602904588,0.25,0.4,0.3,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.2162671661789055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.22342652,0.3846153846,0.2197802198,0.3846153846,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.634728988229636,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.21412129,0.4,0.3428571429,0.2285714286,0.028571428569999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.378896741664954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.29890072,0.34653465349999996,0.396039604,0.2475247525,0.0099009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.661550519424199,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.62419529,0.4186046512,0.3720930233,0.1860465116,0.02325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.552612935249416,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,5.021245473208271,0.0189024787568605,0.00542838949966448,0.0161874266221436,0.00564673685028802,0.0063903753402389,0.0111802988958026,0.936264294035002,0.0913658402077254,0.0913658402077254,-0.908812673116613
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.59373115,0.3783783784,0.3783783784,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.484470400750307,0.220192249542946,0.000764987158036526,0.00117389921248248,0.000355328494502401,0.000727082388944626,0.00146163086877099,0.775324822334317,0.909323670538887,0.909323670538887,0.25860546111465654
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.02523135,0.35897435899999997,0.41025641030000004,0.20512820510000002,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.474947598938117,0.0634606467339624,0.00208550415241484,0.000693953783467295,0.000703971489002912,0.00107462659382075,0.00306678394465369,0.928914513302678,0.68813569412733,0.68813569412733,-0.057081784806354334
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.414493824811383,0.0115671522937999,0.000329262998462127,0.000782715410474643,0.000454168201139608,0.00050928396392566,0.0365052454816706,0.949852171650527,1.45919493888772,1.45919493888772,1.0434010414727322
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.50825332,0.5283018868,0.2641509434,0.1886792453,0.01886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573163389853005,0.0289504727873473,0.000587630380490671,0.00098172979734669,0.000247631664832521,0.000530890620697785,0.00148666967519347,0.967214975074092,1.18732779204068,1.18732779204068,0.6553827041429786
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.02959744,0.5090909091,0.2909090909,0.1818181818,0.01818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.424367475163407,0.01918176556647,0.0010650954164724,0.0022206234626453,0.00126505200881015,0.0010329415925789,0.00258134917445057,0.972653172778573,0.519739549496667,0.519739549496667,-0.29742267487018065
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.0526464,0.43243243239999996,0.32432432429999997,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.646312129319266,0.0173760673957131,0.000550323482827711,0.00231355504088989,0.000799250291024724,0.00171157517792979,0.00187915335599706,0.975370075255618,0.641975082983608,0.641975082983608,-0.12296382974571453
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87880561,0.3902439024,0.3902439024,0.1951219512,0.0243902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.627909672957581,0.031425165165133,0.00121897501467252,0.00336392108926765,0.00273184674446895,0.00365496097119473,0.00253008289994281,0.95507504811532,0.292484943880311,0.292484943880311,-0.6217684269937327
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.72896002,0.41025641030000004,0.3076923077,0.2564102564,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.6141299273595635,0.00243290161785256,0.00374029360494432,0.00771109158226845,0.00256075951190699,0.0024473081411263,0.00398520450059787,0.977122441041304,0.29000081469118,0.29000081469118,-0.6253138633910964
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2936051730729785,0.0291199872991734,0.000702410023626044,0.0253755412996204,0.0176881988849176,0.000962484515645204,0.00126799370807735,0.92488338426894,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.596835549198034,0.0642873127295256,0.000194616801396495,0.00548703707264694,0.0163820187916684,0.000849254927099769,0.000518055392084143,0.912281704285579,0.772854925639995,0.772854925639995,0.06383247693007311
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.26769266,0.3783783784,0.3783783784,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.284827171296749,0.000820324065776298,6.77505055763446e-05,0.00130838737685328,0.00203458073148474,0.00044026025400656,0.00179231955954145,0.993536377506761,0.647354606156059,0.647354606156059,-0.11528598539707118
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.69845587,0.35897435899999997,0.41025641030000004,0.20512820510000002,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.355939299910563,0.000606683031689403,0.000350488437662207,0.00200552330636915,0.00341592792036262,0.00135658595795651,0.00484812686613966,0.98741666447982,0.429472560198128,0.429472560198128,-0.42625489130230415
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.73864775,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.210051369934071,0.0506054803736383,0.000934742670841204,0.00195746112246746,0.00131704918881155,0.00229254534633995,0.00362188526923176,0.93927083602867,0.295296757118666,0.295296757118666,-0.6177553084162161
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.22254695,0.5283018868,0.2641509434,0.1886792453,0.01886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.19614876167715,0.000394517913167851,0.000925918583325644,0.00219111536287718,0.00192843383777798,0.00141208216065332,0.00279803133939282,0.990349900802805,0.423957111788814,0.423957111788814,-0.43412673292138043
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.73562869,0.5090909091,0.2909090909,0.1818181818,0.01818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.324000197151533,0.0149763371723649,9.09516394922477e-05,0.00865819492777344,0.00337158611087041,0.000870833891384162,0.00234291805381448,0.9696891782043,0.799987755503576,0.799987755503576,0.10255740435442702
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.73441264,0.43243243239999996,0.32432432429999997,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.638604962074329,0.00412763242238728,0.000587351434637121,0.00125519721482213,0.00156835329887146,0.00151910105091065,0.00332452673735467,0.987617837841017,0.519710678404319,0.519710678404319,-0.29746388070685387
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.55362203,0.3902439024,0.3902439024,0.1951219512,0.0243902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.465448242812954,0.001908149535057,0.00051106883667359,0.00195557181028906,0.00222543526142979,0.00102554934782431,0.0036709617373884,0.988703263471338,0.559906246507883,0.559906246507883,-0.24009535462913364
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.4082575,0.41025641030000004,0.3076923077,0.2564102564,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.439351701293151,0.0164941051995163,0.00133624924425635,0.0136411729141475,0.0068725438331318,0.00281561744256348,0.00565863059250302,0.953181680773882,0.404416041627467,0.404416041627467,-0.4620164343493942
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.348211286179151,0.25310386523031,0.000588156076259717,0.140706646889545,0.17621759673582,0.00218337900345845,0.000839731767209391,0.426360624297398,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.574298522321004,0.0173152888243317,0.00170643426094864,0.0181271736370668,0.0103847448319841,0.00234708518590686,0.00464250497463967,0.945476768285122,0.880302275630684,0.880302275630684,0.21718510735044552
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.54771521,0.3296703297,0.2197802198,0.4395604396,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.530015512387331,0.0022188818222417,0.00151967168045253,0.0265741083102934,0.00935341146520975,0.00161955884356527,0.00594450434134348,0.952769863536894,0.693395601815244,0.693395601815244,-0.0495746598769834
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.03951812,0.41322314050000003,0.16528925619999998,0.41322314050000003,0.00826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.640537329825382,0.0191565810814788,0.00120917820488213,0.00564887782228727,0.00368324602436162,0.00270413188019715,0.00625226385441887,0.961345721132374,0.702078866162311,0.702078866162311,-0.037181600128431615
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,10.8033785,0.2702702703,0.32432432429999997,0.3783783784,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.2431955089544555,0.0191175904912105,0.0046774627841674,0.0253721583259607,0.0153479247605493,0.0105242912643767,0.0240873946993884,0.900873177674347,0.168910555827937,0.168910555827937,-0.7981381323616322
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,9.298704135,0.25,0.4,0.3,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.822697998516666,0.00783638212803346,0.00315432464612104,0.0156004284210389,0.0122536904537434,0.00649575798551451,0.014293561001533,0.940365855364016,0.26946434750834,0.26946434750834,-0.6546242303969191
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.90666525,0.3846153846,0.2197802198,0.3846153846,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.291292751611072,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.89035919,0.4,0.3428571429,0.2285714286,0.028571428569999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.388753955423308,0.0457836478243602,0.00256820195313693,0.0933595380902435,0.040121791020458,0.00303459231576053,0.00719748271402532,0.807934746082015,0.638042293066864,0.638042293066864,-0.12857684559650717
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.97231927,0.34653465349999996,0.396039604,0.2475247525,0.0099009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.500031867864786,0.00367784574047392,0.00111977791364668,0.0109807451773001,0.00533981749985873,0.0035253353907892,0.00945759694134628,0.965898881336585,0.664597706735618,0.664597706735618,-0.09067602683869287
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.30278396,0.4186046512,0.3720930233,0.1860465116,0.02325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.578518154990665,0.00602415700375336,0.00352191807012307,0.0129438874596237,0.0112365957475355,0.00705054455561779,0.0163551166761144,0.942867780487232,0.387412476367661,0.387412476367661,-0.486284519689253
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DOPE,1,0,0,0,14.78083639,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.373742415086184,0.00132025329631253,0.000860633620224201,0.00503931327076771,0.0029913613071963,0.00270028184029275,0.0088532339643477,0.978234922700859,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.434619084793052,0.00770185399584477,0.00244833711322221,0.0462111239750686,0.0198642411939162,0.00381226904350308,0.00922041774380283,0.910741756934642,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,11.7812451,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.485936098064394,0.00448668985970796,0.00155299888410839,0.00808200908228358,0.00771278024096098,0.00385266053622471,0.00536687174407294,0.968945989652641,1.22295554827804,1.22295554827804,0.7062318887477964
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.73444252169223,0.00221922165343577,0.00134658478491355,0.00928071520245763,0.0103471897935628,0.00308928870366618,0.00305991935175966,0.970657080510204,2.4848301850992,2.4848301850992,2.507223675274371
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.7140245909001735,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.85564,0.309,0.363,0.259,0.069,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.002960000420248,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.10629825,0.337,0.322,0.28800000000000003,0.054000000000000006,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,3.9917579734469997,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.076607527,0.215,0.44299999999999995,0.27399999999999997,0.067,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.150252194160397,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.262126773,0.285,0.369,0.233,0.114,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,3.9384701754429945,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.14390228,0.47,0.40399999999999997,0.057,0.068,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.139158578011894,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.465333240800292,0.0929588198875335,0.00109661539851913,0.0103406974639253,0.00262333547972377,0.00257373980843396,0.00319533888859958,0.887211453073265,2.49616154919077,2.49616154919077,2.5233961959539766
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,0.41,0.395,0.16,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.25063580654847,0.00217929592656579,0.00233573351378476,0.00718449647353577,0.00718369422949875,0.00471157922942054,0.00408542775852615,0.972319772868668,1.71461830076508,1.71461830076508,1.4079502315467747
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.40653622,0.31333300000000003,0.31333300000000003,0.31333300000000003,0.06,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.188896879163323,0.0142737392382439,0.00348189340868737,0.00880858320276677,0.0038525568856599,0.00593274588142816,0.00610316587084082,0.957547315512373,0.645718762121967,0.645718762121967,-0.11762071943757772
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,0.5,0.235,0.235,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.343935283551159,0.0065593281978378,0.00138907609400551,0.00613919753007927,0.00613411120238244,0.00366825953495706,0.00406194129869205,0.972048086142046,1.35219591573978,1.35219591573978,0.890688278863242
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.200348974,0.22,0.22,0.5,0.06,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.057161771094385,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.72417162,0.27,0.27,0.41,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.102973888920155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.092439729,0.16,0.395,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.127940511650616,0.0097349353786325,0.00823434520879355,0.0380775286515883,0.0189007253206434,0.0281939358827934,0.0273826912679074,0.869475838289641,0.161929321885153,0.161929321885153,-0.8081019945583146
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,0.395,0.16,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.116269119637892,0.00176070173692806,0.00134882241229812,0.00721447825021801,0.00277771416530431,0.00258248336542972,0.00338400053115958,0.980931799538662,0.834918279031508,0.834918279031508,0.15241147395626697
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.312676556539088,0.0122849683487715,0.00187692747865846,0.313004652084084,0.0267625511357853,0.00478000951875277,0.00400214034383056,0.637288751090117,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5612182984589085,0.00230427148121394,0.00151653786120671,0.00981883965091339,0.0195498469521307,0.00278714514326426,0.00256552165624032,0.961457837255031,3.54213716664653,3.54213716664653,4.0162493217529285
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,0.41,0.395,0.16,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.2756934238792645,0.00339636246099529,0.00439836397767252,0.00922438120812044,0.0070906355917358,0.00777777401057153,0.0070228258793507,0.961089656871554,1.60048193764837,1.60048193764837,1.2450508067393784
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,0.5,0.235,0.235,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.300138475201197,0.0251900613139205,0.0263858529561065,0.0690244086529141,0.0290319859464883,0.0512059292322219,0.0395084822769767,0.759653279621372,0.244442812501583,0.244442812501583,-0.6903358436733202
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,0.395,0.16,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.035478809355064,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.314416735011824,0.00832740543716945,0.00279899792781369,0.0133506530995165,0.00590470004845411,0.00800781451355169,0.00611088774111073,0.955499541232384,1.4036171732161,1.4036171732161,0.9640785029516001
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.46964291,0.32299999999999995,0.32299999999999995,0.32299999999999995,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.122932019074013,0.00935369123549862,0.00681432683334856,0.0266295187790274,0.0091342786879667,0.0148394527045059,0.0109795829907811,0.922249148768872,0.807897092094877,0.807897092094877,0.11384588723707807
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.214347354616797,0.00175971204953205,0.0023945553766021,0.00864096914216858,0.00287247113967731,0.00354165273920712,0.00438932700137801,0.976401312551435,2.1807873939408,2.1807873939408,2.073283128685432
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.297557478047431,0.0163588203416613,0.0050349858804786,0.141665503002976,0.0268932928836599,0.0108166459136593,0.00842178986187252,0.790808962115693,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.623991940228679,0.0114998638575461,0.00130788860611426,0.00505223783079306,0.0046933168158669,0.00183202266239377,0.00287251942980201,0.972742150797484,1.19732008331576,1.19732008331576,0.6696440530835793
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.47398367,0.415,0.405,0.16,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.261975403606051,0.0120973279883405,0.00779128029381303,0.0260350268299895,0.0160802201335602,0.0156019499205845,0.0170739234476819,0.90532027138603,0.213285375768679,0.213285375768679,-0.7348048313269125
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.72570651,0.405,0.16,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.168678699274804,0.00644850088058007,0.00798921970887525,0.0221223520376599,0.0111631004951633,0.0106463671035197,0.00996963598739929,0.931660823786802,0.29077874869216,0.29077874869216,-0.6242035686713655
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.63764671,0.415,0.405,0.165,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.40562108352751,0.0088141667427258,0.00585903666298478,0.0157870816204507,0.010986042994209,0.00978368783097364,0.0102623946891479,0.938507589459508,0.370029347989408,0.370029347989408,-0.5110943308383519
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.402441819416474,0.154933534385178,0.00229861102597737,0.00525615721273492,0.00408539799683711,0.0022876287732977,0.00287249757879639,0.828266173027179,1.34933481107146,1.34933481107146,0.88660480982624
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.91076362,0.42,0.405,0.165,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.607168188650764,0.0408588610755303,0.0177373482989948,0.0425327283385076,0.0277718677406049,0.0276871974121274,0.0218927074965806,0.821519289637654,0.158736230637426,0.158736230637426,-0.8126592864976097
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.4277167605909975,0.00307921600642319,0.00224989559352084,0.00599370029233814,0.00443157985269048,0.00263031532778781,0.00293093049696406,0.978684362430275,1.27822314397057,1.27822314397057,0.785111741784596
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.444179499895966,0.0412236553892641,0.00390663231476925,0.121517080143859,0.0188177267921366,0.00482332620655526,0.0073631886059774,0.802348390547439,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573473099244837,0.00689869445402741,0.00600089779665737,0.0191135089301672,0.00620664286397134,0.00981653359048003,0.0097967903769499,0.942166931987747,0.749333285576466,0.749333285576466,0.030261566378477555
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.88644869,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.688591794127164,0.00886147101476089,0.00436553876298869,0.0150948084008648,0.00476112441477112,0.00826588994437132,0.00836456609804533,0.950286601364198,0.883781845590108,0.883781845590108,0.22215127176544153
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.877221176,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.829113417472866,0.00517423746484337,0.00420818785762778,0.0136338012801862,0.00389526355348657,0.0081026937251479,0.00825574629036951,0.956730069828339,1.02766134878372,1.02766134878372,0.4275011503825392
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4595662121293,0.025369932029363,0.00629969301959379,0.0185849502075566,0.00668329267445478,0.00984673129800659,0.00995848867776924,0.923256912093256,0.773367707896157,0.773367707896157,0.06456433777003012
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.306031912,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.528073135603124,0.00974026247143072,0.00459547921939943,0.0155882894773368,0.00424301614179951,0.00735125258984654,0.00918675243548622,0.949294947664701,0.925634770529548,0.925634770529548,0.28188523570969626
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,6.950074466,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.730921391293652,0.0307398296858454,0.00502448817507942,0.0144391987292623,0.00475975114719379,0.00732990645958348,0.00864531856689022,0.929061507236145,0.282355212986546,0.282355212986546,-0.6362259345836732
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3578620076745835,0.0575651939642587,0.00224327504140443,0.293214190330324,0.103801109257072,0.00316596887134689,0.00243404296405076,0.537576219571543,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1515122352784415,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.2656332579940335,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.431173877940127,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.436396441739405,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.5666372362713075,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.765586907393996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.149936935645806,0.0412282002133458,0.00282906106065428,0.0100452919302821,0.00294646346634102,0.0035555046437446,0.00510039590268196,0.93429508278295,2.31132936702855,2.31132936702855,2.259597216050143
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.244200317766478,0.0307672106546614,0.0492440442693678,0.143087600825361,0.0409904333145751,0.0410729694241231,0.0628737572688051,0.631963984243106,0.159668526820479,0.159668526820479,-0.8113286806519148
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.430459592195472,0.0144382835185698,0.030629687100469,0.0904231657039977,0.0327120644783899,0.0374915496460484,0.0408664371206098,0.753438812431916,0.342029093157046,0.342029093157046,-0.551057277633741
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.560277417097355,0.064087583051715,0.00731756531038673,0.0186036957891068,0.0053871458118381,0.00655845861152129,0.0086069303650773,0.889438621060355,2.14638048731397,2.14638048731397,2.024176383509215
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.667205576907544,0.00310349569550498,0.00416831577034203,0.0115025538737423,0.00349250282837259,0.00500126547712412,0.00690260249517487,0.965829263859739,3.35844880423818,3.35844880423818,3.754082841561727
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.713127327493184,0.00089376253365906,0.00183788568066981,0.0054363636464257,0.00195410248071216,0.00225811087193407,0.00383533887250888,0.98378443591409,3.24722414573894,3.24722414573894,3.595339103815341
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.359653205696989,0.0828383439279835,0.00565653685524585,0.157248489872984,0.00928479521934879,0.00688752099561758,0.00841921269728692,0.729665100431533,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.634728988229636,0.00818072805535472,0.00273349879854757,0.0119346096951512,0.0075308964437597,0.00591367796700706,0.00578329104170321,0.957923297998477,0.213428398303373,0.213428398303373,-0.7346007045438266
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.15051107,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.7140245909001735,0.0160361616147136,0.00185083446366488,0.00730973501824061,0.00349956550575257,0.00416153151105757,0.00426975100661699,0.962872420879954,0.319359456002154,0.319359456002154,-0.5834121797200126
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.327596879,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.822697998516666,0.0208671125611406,0.0200298903914976,0.0765668274895919,0.0297655881927753,0.0442427715485906,0.0417155046265625,0.766812305189841,0.0431568482237034,0.0431568482237034,-0.9776182391106099
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.548282323781043,0.235642631118293,0.00357683071882224,0.268183756367962,0.0537803810677977,0.0056567696761597,0.00550191880428196,0.427657712246684,1.0,1.0,0.38802190219888055
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.41834022,0.5,0.075,0.415,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.892602227184663,0.0004,0.0007,0.8627,0.1335,0.0019,0.0008,0.0,0.33,0.33,0.08164550420240263
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.34376213,0.5,0.29,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.935911747900319,0.0015,0.0017,0.585,0.3856,0.0215,0.0046,0.0,0.09,0.09,-0.5587925239809655
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.47881241,0.455,0.075,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.657762636107262,0.0008,0.0009,0.9399,0.0565,0.0012,0.0006,0.0,0.26,0.26,-0.10514892068441307
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.58994389,0.5,0.1775,0.3025,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6520537718869415,0.0009,0.0008,0.8853,0.11,0.0021,0.0009,0.0,0.31,0.31,0.028275668520455245
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.356515817,0.38,0.3,0.3,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.522874943261261,0.0008,0.0012,0.7508,0.2416,0.0048,0.0008,0.0,0.12,0.12,-0.4787377704580445
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.211083767,0.38,0.16,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.802380355275797,0.0003,0.0007,0.8979,0.0985,0.0022,0.0005,0.0,0.45,0.45,0.40186451829408665
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.891852481,0.38,0.23,0.38,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.721173861744398,0.0003,0.0009,0.9061,0.0898,0.0024,0.0005,0.0,0.3,0.3,0.0015907506794815506
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.59856338,0.4596,0.2483,0.2671,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.599152113662528,0.0006,0.0011,0.8386,0.1563,0.0028,0.0007,0.0,0.36,0.36,0.16170025772532357
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.516252746,0.4458,0.19329999999999997,0.3308,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.539030383483547,0.0011,0.0009,0.9163,0.0784,0.0025,0.0008,0.0,0.24,0.24,-0.15851875636636045
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.79855736,0.5,0.075,0.395,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.602165676967792,0.0007,0.0007,0.9622,0.0349,0.001,0.0005,0.0,0.91,0.91,1.6293707389788754
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.789158454,0.425,0.3,0.245,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.506454213048934,0.0013,0.0022,0.7003,0.2848,0.009,0.0025,0.0,0.1,0.1,-0.5321076061399918
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.924427289,0.4471,0.1358,0.3921,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.543294782270004,0.0006,0.0008,0.9464,0.0496,0.0015,0.0011,0.0,0.56,0.56,0.6953986145447971
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.213203287,0.4146,0.2483,0.3221,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.600157644164547,0.0006,0.0011,0.9277,0.0684,0.0014,0.0008,0.0,0.44,0.44,0.37517960045311294
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.766920469,0.38,0.14,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.380775852772229,0.0005,0.001,0.9807,0.0157,0.0015,0.0006,0.0,0.46,0.46,0.42854943613506036
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.9150442,0.5,0.27,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.490881039585964,0.0013,0.001,0.7257,0.2649,0.0061,0.0009,0.0,0.13,0.13,-0.4520528526170708
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.33144164,0.47240000000000004,0.1119,0.3887,0.0271,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.627909672957581,0.0073,0.0639,0.7768,0.1461,0.0042,0.0016,0.0,1.3,1.3,2.670082534776849
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.92222847,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.8543712716215905,0.001,0.001,0.8647,0.1302,0.0025,0.0007,0.0,0.25,0.25,-0.13183383852538677
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.314817884980432,0.0009,0.0007,0.9116,0.0844,0.0018,0.0006,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.42041204,0.49,0.075,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.534747721691546,0.0013,0.0021,0.5194,0.4632,0.0111,0.0029,0.0,0.5,0.5,0.535289107498955
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,15.70987342,0.3425,0.1875,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.191168746857641,0.0011,0.0011,0.7685,0.2222,0.0053,0.0018,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,11.2192693,0.22,0.3,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0028,0.0014,0.4022,0.5806,0.0101,0.003,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.76101632,0.49,0.28,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.154184562578117,0.001,0.0012,0.5862,0.3912,0.0188,0.0017,0.0,0.16,0.16,-0.37199809909414977
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.31421044,0.4461,0.2489,0.27940000000000004,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.155753190350744,0.0041,0.0015,0.5886,0.3825,0.0211,0.0022,0.0,0.13,0.13,-0.4520528526170708
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.60470229,0.3211,0.2489,0.4044,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.104294893075269,0.0017,0.0016,0.5892,0.3913,0.0129,0.0033,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.00750041,0.49,0.1875,0.3125,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0111,0.0048,0.1796,0.7293,0.0671,0.0082,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.77390107,0.4213,0.1875,0.38130000000000003,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.33204826486764,0.0167,0.0049,0.2598,0.6793,0.0289,0.0104,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.21646499,0.4561,0.1364,0.38189999999999996,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.365643155423357,0.0042,0.0015,0.3443,0.6172,0.0298,0.003,0.0,0.2,0.2,-0.2652584277302551
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27353562,0.445,0.075,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.436751534363128,0.0067,0.0013,0.5909,0.385,0.0142,0.0019,0.0,0.22,0.22,-0.21188859204830776
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27759176,0.49,0.3,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0122,0.0028,0.2395,0.6818,0.0594,0.0044,0.0,0.08,0.08,-0.5854774418219391
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.75114553,0.345,0.3,0.325,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.248495242049359,0.0029,0.0024,0.3338,0.6429,0.0151,0.0029,0.0,0.07,0.07,-0.6121623596629128
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.61008,0.3936,0.2489,0.3419,0.015600000000000001,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.384523514872469,0.0141,0.0106,0.3243,0.5845,0.0592,0.0073,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,12.46688772,0.24,0.3,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.796616650559047,0.0064,0.0026,0.3777,0.6006,0.0093,0.0034,0.0,0.1,0.1,-0.5321076061399918
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,0.465,0.075,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0024,0.0028,0.4642,0.5174,0.0093,0.0039,0.0,0.81,0.81,1.362521560569139
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.04448224,0.3736,0.2994,0.3171,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.370712874773608,0.033,0.008,0.1094,0.8115,0.0325,0.0056,0.0,0.11,0.11,-0.5054226882990182
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.623010104116422,0.0087,0.0033,0.2348,0.7393,0.011,0.003,0.0,0.36,0.36,0.16170025772532357
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.375757021660286,0.0019,0.0023,0.9077,0.0818,0.0033,0.003,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.34776106,0.49,0.075,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.943782987108415,0.0542,0.0001,0.3146,0.0378,0.0014,0.0006,0.5913,1.14,1.14,0.5878348176473546
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.630330503,0.3425,0.1875,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.395682961121367,0.03,0.0006,0.0837,0.0261,0.002,0.0013,0.8563,0.78,0.78,0.07403017792270697
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,5.746375559,0.22,0.3,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.264087336809195,0.0156,0.0014,0.0138,0.0104,0.0025,0.0031,0.9532,0.32,0.32,-0.5824979728365652
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.15734025,0.49,0.28,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.513054897080286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.812051718,0.4461,0.2489,0.27940000000000004,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.470495282661489,0.009,0.0004,0.0178,0.0948,0.0017,0.0003,0.8762,1.05,1.05,0.45938365771619283
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,7.893697629,0.3211,0.2489,0.4044,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.289088639014612,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,0.46,0.46,-0.38268505738809105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.08675917,0.49,0.1875,0.3125,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9684234452869465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.13512977,0.4213,0.1875,0.38130000000000003,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.906015244966153,0.0128,0.0,0.028,0.0208,0.0006,0.0,0.9378,0.93,0.93,0.28811544447464355
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.43848511,0.4561,0.1364,0.38189999999999996,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.525044141508807,0.0635,0.0002,0.2019,0.083,0.0009,0.0003,0.6502,1.5,1.5,1.1016394573720025
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.44748395,0.445,0.075,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4520190064939165,0.011,0.0005,0.3972,0.0536,0.0016,0.0009,0.5352,1.45,1.45,1.0302777018546903
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.57169095,0.49,0.3,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.86830338551846,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.009941019,0.345,0.3,0.325,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3476939555933765,0.0165,0.0,0.0427,0.0616,0.0035,0.0028,0.8728,0.42,0.42,-0.43977446180194085
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.301142352,0.3936,0.2489,0.3419,0.015600000000000001,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.629862798578463,0.0246,0.0,0.1245,0.0895,0.0015,0.0023,0.7576,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,6.525773643,0.24,0.3,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.732683506287051,0.006,0.0012,0.0205,0.0177,0.0008,0.0,0.9538,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.31765932,0.465,0.075,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.81380905109942,0.073,0.0,0.0373,0.0149,0.0,0.0,0.8748,1.01,1.01,0.40229425330234303
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.01888288,0.4637,0.075,0.4421,0.0192,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.706823839714591,0.0145,0.0004,0.1165,0.019,0.0007,0.0011,0.8477,1.94,1.94,1.7296229059243498
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.30562834,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.73795129722191,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,1.9,1.9,1.6725335015104998
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,9.480986593,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.302712827954156,0.0455,0.0,0.324,0.073,0.0011,0.0012,0.5551,1.0,1.0,0.38802190219888055
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0253701689981931,0.00985209592098701,0.307949537646453,0.622300893638244,0.0174680522283724,0.0170592515677505,0.0,0.0,,
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584559232083967,0.00894763570081526,0.00182903773179144,0.430416319953847,0.549730482792046,0.00757886856613304,0.0014976552553668,0.0,0.0019532059842532,0.0019532059842532,-0.793744670428099
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.5827200571505,0.00757568328250189,0.00220510873539676,0.728025615125869,0.236446776884745,0.0226429923353559,0.00310382363613184,0.0,0.0011482099710543,0.0011482099710543,-0.7958927956755514
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6888677450096585,0.00599960547383456,0.00187471922407934,0.58725363712808,0.393842224090862,0.00908706069367491,0.00194275338946932,0.0,0.0005585876781053,0.0005585876781053,-0.7974661979200065
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0207124354254999,0.00767807173489595,0.560331852523788,0.3797189836544,0.0206003960524344,0.0109582606089812,0.0,0.0001489580680618,0.0001489580680618,-0.7985592911689305
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0084525958204246,0.00170600389954699,0.807774257087237,0.172171860632781,0.00851123850670424,0.00138404405330582,0.0,0.0052460712339961,0.0052460712339961,-0.7849576865630203
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0142965461163966,0.00273099369058116,0.2951874813445,0.196790510597468,0.00567584660232592,0.00900724719724339,0.476311374451485,0.0033203605888808,0.0033203605888808,-1.0344742729359027
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584559232083967,0.0426258503334726,0.000887127042175757,0.102099604743599,0.057196348771858,0.00222434780081794,0.00162961025671667,0.79333711105136,0.0465195426566469,0.0465195426566469,-0.972818883550547
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.5827200571505,0.0182648912592805,0.000462867676668248,0.083073077462289,0.0429608616930204,0.00195825764287227,0.000923423624969053,0.852356620640901,0.0509209522037464,0.0509209522037464,-0.9665370373099135
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.6888677450096585,0.0068908069603713,0.000629547873998548,0.021394314943629,0.042448777163022,0.00198708372142952,0.00248444060475972,0.92416502873279,0.016201262972428,0.016201262972428,-1.0160901968011615
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0116932676375475,0.00103739027764326,0.0525071135910941,0.0215477599193875,0.00368874758435242,0.00400972460855577,0.905515996381419,0.006104461793755,0.006104461793755,-1.0305007059455489
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0237911981258413,0.00067207203055979,0.18334881014348,0.0466442684044473,0.00188246389345958,0.000953648344707904,0.742707539057504,0.0550488822731985,0.0550488822731985,-0.9606455105817374
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.572543683160998,0.000714997259249526,0.000661552142657172,0.125943320778554,0.801966162874089,0.0693146503097598,0.00139931663568972,0.0,0.0127373438778132,0.0127373438778132,-0.764967287060561
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.358502089626924,0.00147233862420237,0.00107405472963131,0.901430168335102,0.0923159134092667,0.00310160866776492,0.000605916234032228,0.0,0.0763434621140544,0.0763434621140544,-0.5952348831288257
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.396299293960601,0.00110223184180453,0.00161797426133587,0.963322201717795,0.0321995776177804,0.00129202117564397,0.000465993385639812,0.0,0.380376087923258,0.380376087923258,0.21607368094058316
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.351438552905858,0.00061802522712851,0.00208191419961706,0.00520107649990865,0.018780252186508,0.966671145724669,0.00664758616216931,0.0,0.0289886812604962,0.0289886812604962,-0.7216007267742771
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.544995462952021,0.00423798522906651,0.00360605985882706,0.0132163308359338,0.182768863634774,0.789078621894797,0.00709213854660109,0.0,0.0033387326299993,0.0033387326299993,-0.7900474039572776
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0123483310685072,0.00430719249252366,0.0429874465070588,0.751978605237179,0.174073814828135,0.0143046098665965,0.0,0.0005090956767902,0.0005090956767902,-0.7975982669188943
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.790487251761845,0.00153513483125764,0.00147931904743739,0.82338319944907,0.169033483447006,0.00378262362292623,0.000786239602302501,0.0,0.306009500746919,0.306009500746919,0.017627054049161966
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.842058839093973,0.00164287085070931,0.000659195379539964,0.94017588697419,0.0550751037989028,0.00183173459161262,0.000615208405045708,0.0,0.504231824712829,0.504231824712829,0.5465816969768794
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.572543683160998,0.0204881792124896,0.00996076677576078,0.024515683125648,0.0206076067733214,0.0213656753332114,0.0146396167476402,0.888422472031929,0.0035574041476412,0.0035574041476412,-1.0341359560461585
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.358502089626924,0.0789442718629389,0.000859220559164078,0.352513414289749,0.0167725689541561,0.00207992092629201,0.000939235620822743,0.547891367786878,0.128034152082589,0.128034152082589,-0.8564783709716817
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.396299293960601,0.020589791219893,0.00221295822133462,0.77006639472807,0.0336156368936998,0.00141982059640497,0.000804331444027444,0.17129106689657,0.352623838360951,0.352623838360951,-0.5359360852935553
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,1.0,4.351438552905858,0.0518701933925729,0.031230151711712,0.196119602463562,0.0891250765615729,0.225998436967717,0.183312147304902,0.222344391597961,0.0006916766953858,0.0006916766953858,-1.0382260228827003
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.544995462952021,0.0318134391856252,0.0195739470918212,0.0658637908929555,0.0405146823853727,0.0383355214778253,0.0445803960220688,0.759318222944331,0.0007826107131428,0.0007826107131428,-1.0380962386598327
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0496007240706346,0.0248050760368446,0.125156740550784,0.0913290655906173,0.0605654916232193,0.0647609529825488,0.583781949145352,0.000319594239126,0.000319594239126,-1.0387570720282182
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.790487251761845,0.0660465509749711,0.000704686244275338,0.176882938102508,0.134254150019803,0.00301700767902668,0.00146559050061717,0.617629076478799,0.391796497651864,0.391796497651864,-0.4800274905879333
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.842058839093973,0.180962520579808,0.000840183131263393,0.0600498448220066,0.0139903797423045,0.00230022430813273,0.00221494849849946,0.739641898917986,0.515169720881209,0.515169720881209,-0.3039448947184272
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.48897339158558,0.000136174132145422,0.00212452688507234,0.811633900204502,0.179761878637886,0.00385751556458306,0.00248600457581157,0.0,0.767759892635294,0.767759892635294,1.24980418110703
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.675628649636653,0.00268100351583557,0.00240431632025112,0.142040711181502,0.523320437165769,0.324868931367264,0.00468460044937817,0.0,0.0241897161135915,0.0241897161135915,-0.7344067258409619
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.737600973168581,0.00157432110064945,0.00176844882817444,0.053765469363115,0.438156626388713,0.500533090562106,0.00420204375724176,0.0,0.0189624719731265,0.0189624719731265,-0.7483555838832638
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.48897339158558,0.0550309639531662,0.00234353835896855,0.320198252727196,0.282656133384496,0.0064798077198827,0.00202476215621646,0.331266541700075,1.20135127285815,1.20135127285815,0.6753975083349388
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.675628649636653,0.0418659426619505,0.0219153925677162,0.21668759621254,0.199875450362037,0.113029824089051,0.0495629458661235,0.357062848240582,0.0027707272238572,0.0027707272238572,-1.035258728972282
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.737600973168581,0.0234118812216689,0.0071462713755353,0.0426958781226752,0.0464078935005845,0.0346044033846598,0.0235967118628926,0.822136960531984,0.0055457738057274,0.0055457738057274,-1.0312980850577906
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00767358537807448,0.00233215653996207,0.0713684727707158,0.307444763898641,0.0172788380976704,0.00511228295653041,0.588789900358405,0.0063917829512014,0.0063917829512014,-1.0300906311016962
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.579236803961587,0.00833063062779389,0.00173987762429209,0.156651961849343,0.112205138324295,0.00895304009765426,0.00427289873828259,0.707846452738339,0.269390835357988,0.269390835357988,-0.6547291495189385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0158311033527607,0.00109353847138243,0.0200990623529318,0.00589717673503959,0.00332080816189693,0.00297802720282806,0.95078028372316,0.0070114291767852,0.0070114291767852,-1.0292062502525494
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,5.0755487449389,0.0138253404297663,0.00670375922221507,0.064918033729737,0.0310082272870404,0.0307691214666871,0.0156091189056244,0.83716639895893,0.0111434256880136,0.0111434256880136,-1.023308919755896
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.402809173856411,0.0144051248882893,0.000525788660297221,0.125667067331117,0.214373546599095,0.00410880851120861,0.00177167337754258,0.639147990632451,0.176512628889736,0.176512628889736,-0.7872881867764152
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00115119797114568,0.0003959818507672,0.0538124209539168,0.93604524664705,0.00736502972190904,0.00123012285521143,0.0,0.0261518819859255,0.0261518819859255,-0.7291707023316024
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.579236803961587,0.0010942059599737,0.000714578151988552,0.367034511120116,0.62078160479883,0.0079478856978032,0.00242721427128835,0.0,0.970510173989973,0.970510173989973,1.7908416411254202
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0376230130625874,0.00236009027623813,0.247039705692743,0.697452972603375,0.0104681865382628,0.00505603182679352,0.0,0.0013884403431976,0.0013884403431976,-0.7952517429011965
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,5.0755487449389,0.00873826813676438,0.00145112475939544,0.193065080283125,0.778197018798523,0.014433213681334,0.00411529434085825,0.0,0.165721665234437,0.165721665234437,-0.35672988242469916
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.402809173856411,0.00532422079532615,0.00061084449763591,0.522469676271313,0.459778984209221,0.00966894873803684,0.00214732548846694,0.0,0.161020662402855,0.161020662402855,-0.3692744698577941
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584763376210429,0.0318391346416656,0.000341552225113717,0.113678281409446,0.242279767731552,0.00387550619454475,0.000871625110337537,0.60711413268734,0.649833386251602,0.649833386251602,-0.11174818341388475
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.746322465743975,0.0548193142492001,0.000263362025026913,0.0902956804122817,0.160837629010128,0.00315355508353847,0.000739500993108033,0.689890958226717,1.16375238999006,1.16375238999006,0.6217350625958049
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.651385609785055,0.0172566765287249,0.00318344365411915,0.0712890876960715,0.171965068058214,0.0218135302099503,0.0115493777455846,0.702942816107335,0.00327405282427,0.00327405282427,-1.0345403650034368
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584763376210429,0.000599963927151076,0.000397997752734626,0.420976508827142,0.560178394908249,0.017044159994242,0.000802974590480822,0.0,0.25255828640642,0.25255828640642,-0.1250070722684871
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.746322465743975,0.000524374578838527,0.00061514916196369,0.547432124587029,0.435435317287124,0.015309113403191,0.000683920981854007,0.0,0.568394489552276,0.568394489552276,0.7177992409467366
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.651385609785055,0.00171983501988967,0.00189561016704693,0.0120716635806003,0.711278646835123,0.270438826106656,0.00259541829068387,0.0,0.0112897234542117,0.0112897234542117,-0.7688302502674332
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0047850951415261,0.000675911772575438,0.46069265034102,0.522359359837259,0.0109775121699624,0.00050947073765779,0.0,0.773205414607926,0.773205414607926,1.2643355117511204
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.633757642840004,0.00198911414189635,0.00126811595413123,0.543867583730296,0.438842770521552,0.0129988635137729,0.00103355213835123,0.0,1.98493053910539,1.98493053910539,4.497814051056962
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.609759638321899,0.00125031423153586,0.0004860362025215,0.538249539726811,0.445414640899446,0.0137801694455006,0.000819299494184621,0.0,0.291137444797345,0.291137444797345,-0.022058905064912687
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.392884144674663,0.00226285185388551,0.000562872305858137,0.731364439797527,0.256932619347553,0.00825451238600619,0.000622704309170273,0.0,1.82872279459479,1.82872279459479,4.080974968218046
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0442923458834068,0.00055452650331333,0.106459881295074,0.192526940733964,0.00311682882196998,0.000623042068808978,0.652426434693463,0.672431538902446,0.672431538902446,-0.07949530652163618
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.633757642840004,0.0374610013402809,0.0005350551106764,0.260855439538844,0.469905543128085,0.00469334055693451,0.000912093945676405,0.225637526379503,1.69276100831231,1.69276100831231,1.3767547363410753
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.609759638321899,0.0836645231428707,0.000419599806684375,0.0235684307001288,0.0712275212970175,0.00119681308497475,0.00178295859414992,0.818140153374174,0.426058290183635,0.426058290183635,-0.431127857343191
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.392884144674663,0.0512990735432809,0.000672189655491244,0.187343972483681,0.232187436433234,0.00314791870850824,0.00146679734452725,0.523882611831278,1.30784095113947,1.30784095113947,0.8273833160675146
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,17.78759767,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.751259891859986,0.00405799702984203,0.00225047224182105,0.719270208750414,0.257208699720685,0.0138718178214465,0.00334080443579049,0.0,1.25160610942024,1.25160610942024,2.540943835364252
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.666265285347902,0.00272982965803786,0.000172365352517303,0.498048022051036,0.479137442306018,0.0180316959727267,0.00188064465966415,0.0,0.155537169131505,0.155537169131505,-0.3839071266005448
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.904756125442696,0.00273286200255075,0.00260055069792003,0.431146257918051,0.50349018951458,0.0550138028095967,0.00501633705730229,0.0,0.021985308799366,0.021985308799366,-0.7402891686477768
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.733211535868976,0.00166528576158017,0.000176886038620712,0.205207225042143,0.750916028545382,0.0392720451710516,0.00276252944122191,0.0,0.120096690961961,0.120096690961961,-0.478479751420455
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.858726543710496,0.00383743159330312,0.00248950729214128,0.555903422423481,0.380445635709031,0.0515668712566801,0.00575713172536402,0.0,0.0526538412251038,0.0526538412251038,-0.6584504418393717
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.666265285347902,0.0567289157085495,0.00653348267008008,0.064839577285576,0.335055277453961,0.0144955694225392,0.0143736618741762,0.507973515585118,0.268311366051918,0.268311366051918,-0.6562698060131026
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.904756125442696,0.0248552898268163,0.0125192728735768,0.0725307642598596,0.0355254691282667,0.0214395648154144,0.0248745799236939,0.808255059172372,0.0741845243461588,0.0741845243461588,-0.9333344503561898
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.733211535868976,0.0883917007893502,0.00174599838911923,0.0536405332414895,0.100118671210748,0.00771990063396103,0.00639776118235737,0.741985434552974,0.528035509086713,0.528035509086713,-0.28558239006925334
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.858726543710496,0.0175679405294797,0.00960173891174304,0.0903179131752613,0.0388184937379254,0.0182497546285787,0.0249045868533177,0.800539572163694,0.125181510399577,0.125181510399577,-0.8605497613389135
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.62870578,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.765586907393996,0.00159278655447388,0.00186611160196327,0.488795918944862,0.485247409700546,0.018616198181097,0.00388157501705755,0.0,0.352570746370957,0.352570746370957,0.14187535545424673
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.61880246,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.82374330878754,0.000875415234709484,0.00127375854285246,0.683377837104949,0.304003257921165,0.00820355561270421,0.00226617558361995,0.0,0.943420561172443,0.943420561172443,1.7185532318874628
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.433313679041901,0.000602190120987361,0.000576528881915898,0.00566197423128506,0.0161763859347042,0.971683265119797,0.00529965571131053,0.0,0.0305789310371634,0.0305789310371634,-0.7173571583105779
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.70929826,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.356324137321509,0.00187378052819512,0.00157654975652554,0.0163863796216318,0.0648246159165097,0.905280007427939,0.0100586667491993,0.0,0.003875136361479,0.003875136361479,-0.7886160150068647
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.17273956,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.440767129696482,0.00301049906217731,9.21592223531261e-05,0.00380096827414773,0.0130323481002541,0.97657327492354,0.00349075041752818,0.0,0.0274401441027376,0.0274401441027376,-0.7257329854571254
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.349632566862877,0.00273989274094748,0.00161018393061426,0.0112824839963327,0.0583352940699212,0.919247401685963,0.00678474357622127,0.0,0.0081601896883771,0.0081601896883771,-0.7771813854096181
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.90345652,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.662778498608405,0.00349315451118928,0.00171298178399312,0.037797325974731,0.242816837972913,0.706569889763285,0.00760980999388795,0.0,0.0136767051395404,0.0136767051395404,-0.7624606092513427
O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,0,0,1,,4.405498990859024,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,,4.815106909815019,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.562053894914463,0.00241700650155169,0.00189161759954923,0.0117804592312353,0.0588098364115177,0.918016488291877,0.0070845919642692,0.0,0.288385322760908,0.288385322760908,-0.029402920107978105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.667205576907544,0.00146771264056884,0.000853267380299107,0.00521853383313367,0.0984194458399351,0.890752405611161,0.00328863469490281,0.0,0.174730948641107,0.174730948641107,-0.3326886836733955
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.94799221,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.701389043728634,0.00256320924432886,0.00193796271600952,0.0128146756680969,0.0418402586947232,0.934553052894321,0.00629084078252029,0.0,0.0492674291707299,0.0492674291707299,-0.6674870545840368
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.460491174618648,0.00101051612937229,0.00153512067382825,0.00950098551353592,0.161931963893941,0.822835993399315,0.00318542039000704,0.0,0.105055900803977,0.105055900803977,-0.5186159763833679
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,19.0764718,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.505460341839079,0.00282763425766742,0.00135220428389579,0.101550310310828,0.701364372579719,0.18950529802972,0.00340018053817036,0.0,0.0700302222351868,0.0700302222351868,-0.6120817118766197
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.18453431,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.684905154006945,0.0025903109842197,0.00122267327648511,0.0959380417500791,0.558064631213231,0.339326541744348,0.00285780103163663,0.0,0.0836567108446898,0.0836567108446898,-0.5757195389760648
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.58497913,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.695924549256556,0.00270162630925447,0.000571977156802491,0.072649821877092,0.283620916967858,0.638520904456637,0.00193475323235631,0.0,0.108372702997361,0.108372702997361,-0.5097651169808466
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O,DSPC,0,0,1,0,16.82518306,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,LYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,4.202899968776446,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.52948326,0.4325,0.25,0.3,0.0175,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,5.029784112935016,0.000951862951033406,0.000642237882584555,0.00747953132811133,0.295137112679544,0.692754163229738,0.0030350919289883,0.0,0.19435393861906,0.19435393861906,-0.2803248961378029
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.10169345,0.3,0.25,0.425,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.833102254034098,0.00529626249319983,0.00246267213977097,0.0289260006923807,0.563065088278535,0.393847703229461,0.00640227316665243,0.0,0.049072760763369,0.049072760763369,-0.6680065256297026
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.72804315,0.38075000000000003,0.17975000000000002,0.41825,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,,4.93014804318357,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.39261658,0.37,0.25,0.37,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.146912912388804,0.000759366167023555,0.000694817987152034,0.00466364025695932,0.212680085653105,0.777593147751606,0.00360894218415418,0.0,0.201238755105862,0.201238755105862,-0.2619528199077537
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.51039532,0.385,0.205,0.385,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.684905154006945,0.00157535225652128,0.00592927130077556,0.00900517890128691,0.366135503933579,0.613833328839362,0.00352136476847493,0.0,0.149329656900936,0.149329656900936,-0.40047182198750214
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.48290639,0.45,0.09,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.869839484130799,0.00147117555088917,0.000927103843315829,0.00585237061645294,0.136146016514374,0.851575135737455,0.00402819773751327,0.0,0.31219703699332,0.31219703699332,0.034138443686487704
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.13138042,0.41200000000000003,0.2235,0.34325000000000006,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.901564199041894,0.00315707422768752,0.0025689389054212,0.0146712017391132,0.327849346901905,0.646061693847123,0.0056917443787501,0.0,0.158541375998041,0.158541375998041,-0.3758904252594646
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.11942242,0.41825,0.14975,0.41825,0.01375,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.039546637590676,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.79492927,0.45,0.225,0.3,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.9141243937154115,0.00113350028034128,0.000566939752127873,0.00680706926467914,0.502661298625749,0.486733894218144,0.00209729785895866,0.0,0.145448415448628,0.145448415448628,-0.4108288829150842
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,12.55393718,0.34325000000000006,0.21725000000000003,0.41825,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.814620410170298,0.001692878443667,0.000820135726038303,0.00868136575507882,0.408928448915581,0.577101122031978,0.00277604912765729,0.0,0.113760366510672,0.113760366510672,-0.495388181160095
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.93959861,0.45,0.075,0.45,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.527640983478854,0.00506334343919377,0.004281344333051,0.0165771717732586,0.226890591170162,0.736348900590883,0.0108386486934518,0.0,0.0547343765642327,0.0547343765642327,-0.6528985503803821
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.59337013,0.45,0.1575,0.375,0.0175,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.810557015713042,0.00141112235558708,0.000749767156842064,0.00637541161251223,0.138880841494329,0.847648476304751,0.00493438107597822,0.0,0.294154433878409,0.294154433878409,-0.0140080944893819
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.66031337,0.3,0.24,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.167639042905921,0.00199236267032557,0.000827577235394216,0.008719084857644,0.192132365846187,0.792330257640873,0.0039983517495764,0.0,0.151793984465988,0.151793984465988,-0.3938957841268362
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.66358165,0.375,0.15,0.45,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.618086411254637,0.00271480786609193,0.00181664538344774,0.00938513027274936,0.132547184736695,0.849509595736892,0.0040266360041233,0.0,0.0950036114384557,0.0950036114384557,-0.5454404279666308
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.26186294,0.45,0.24,0.3,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.098035484377089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.27611859,0.45,0.11381999999999999,0.42618,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.680277658474897,0.00152924607683628,0.00192508702614222,0.0105762053188716,0.167270255683968,0.810875386281306,0.00782381961287527,0.0,0.278754923842637,0.278754923842637,-0.05510156049896443
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.11001923,0.45,0.13445000000000001,0.40445,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.000999438616070677,0.00125158481927741,0.00771842730472846,0.249469737208587,0.735450494958472,0.00511031709286499,0.0,0.286455906115286,0.286455906115286,-0.03455155257492116
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.85662691,0.45,0.16405,0.37595,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.00141338619768439,0.00124322063420737,0.0100450891793794,0.235894751086175,0.745556785166654,0.00584676773589971,0.0,0.264336417833639,0.264336417833639,-0.09357722532293417
O=C(CN(CCCCCCCCCCCC)CCCCCCCCCCCC)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.44559484,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.892641641172089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCCCC,DSPC,0,0,1,0,15.24245185,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.345103280569283,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.310127759130018,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,16.95535314,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.35696520407851,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCC)CCCCCCCCCC)NCCCN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.51030189,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.175309921045205,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.11860943,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.447697327163527,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,16.80841018,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.381651564343798,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,14.7769988,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.2503506625488185,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.386765389021055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.55151343,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.391729410135267,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.85660447,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.114394528387108,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.63293083,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,5.272999558563747,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O,DSPC,0,0,1,0,16.2856483,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.28978103552575,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)NCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.23582504,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.260615499364025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)CN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.75702627,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9788005705762375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.47477668,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.68213122712422,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,19.33366115,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.98780245,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.947340443723942,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CO)=O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.42695266,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.545101659521972,0.0,0.00318490682025255,0.0608074236431031,0.251089505980848,0.00892095913117615,0.00601048706680474,0.669986717357815,0.0815243428420059,0.0815243428420059,-0.9228588036953479
CCCCCCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)=O)CO)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.68206611,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.844974178195408,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H]([C@H](O)C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.77114057,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,thr,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.331522502500113,0.0,0.0131160505661734,0.0817206877958181,0.209957462105326,0.0363069917919837,0.0161572104727098,0.642741597267989,0.0248953087459781,0.0248953087459781,-1.0036817494221935
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4135253017332525,0.0,0.00151329913495755,0.0471551068594211,0.0476760649180962,0.00182335320536251,0.00763287581452213,0.89419930006764,0.35502103370942,0.35502103370942,-0.5325147239258616
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.509649984130679,0.0,0.00235961766437825,0.513627015742916,0.0879412499947796,0.00175822838354556,0.00311254749811917,0.391201340716262,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.496359280129911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC,DSPC,0,0,1,0,14.13296737,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.170425586627436,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.445353484534206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,15.1299087,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.166510173022286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.673109168996284,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.72728505,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.7572902340489245,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.000230328920605394,0.0259372790881254,0.0734981485145439,0.000576894596302152,0.000867946038939987,0.898889402841483,0.486446282346577,0.486446282346577,-0.34493999468492637
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.00183814880222334,0.508470854676458,0.479298868566087,0.00664368457868438,0.00374844337654761,0.0,0.0806697533656258,0.0806697533656258,-0.5836902104683951
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,14.7050121,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.00446051681777838,0.0286140231457339,0.01484311836534,0.00629790100652696,0.01599114503205,0.929793295632571,0.0275210452544693,0.0275210452544693,-0.9999342060867568
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.7050121,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.0104002218216073,0.139229779861971,0.807246421461676,0.041233674188,0.00188990266674509,0.0,0.0040656278842911,0.0040656278842911,-0.7881076899433005
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.00711911642710361,0.153280595121264,0.136743424441396,0.0628412485834964,0.0734141937722642,0.566601421654476,0.0027486514420013,0.0027486514420013,-1.0352902363032352
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.106975953776871,0.247623902989694,0.292657465739291,0.229416263063982,0.123326414430162,0.0,0.001042320755636,0.001042320755636,-0.7961753601769197
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.789157022101107,0.0,0.0386975655052687,0.153034034478582,0.0799184464451532,0.0414429326981307,0.0607210626185958,0.626185958254269,0.0073827728841294,0.0073827728841294,-1.0286762554754216
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,1,0,0,0,0.0,4.639571612705423,0.0,0.135531713474282,0.541180183023036,0.178510571158094,0.0949195329757021,0.0498579993688861,0.0,0.004009461265808,0.004009461265808,-0.7882575701032632
O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,15.91058453,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.639571612705423,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.000231298468169262,0.195828728849491,0.0126185833117857,0.000504922171493209,0.00109315352063243,0.789723313678428,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.00515447939315304,0.962574355010024,0.0304157301451643,0.000918038843316605,0.000937396608342438,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0963955724315343,0.000259669027359828,0.0209585518067849,0.0324510369422159,0.00191021824445882,0.00526970020363582,0.84275525134401,0.95415067884307,0.95415067884307,0.32258414125816925
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0,0.00301852406237983,0.561715155652109,0.427466534539213,0.00675382930885143,0.00104595643744612,0.0,0.469108231863161,0.469108231863161,0.4528546780295592
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.424367475163407,0.00431198097235812,0.000818950238891083,0.0696322838846972,0.0220758004851341,0.00177157151502323,0.00255208415951453,0.898837328744382,0.673380628639453,0.673380628639453,-0.07814073232611048
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.424367475163407,0.0,0.00336772556852765,0.856457049453334,0.133858740361315,0.00483749939645135,0.00147898522037143,0.0,0.274077344076178,0.274077344076178,-0.06758364367522034
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0465123735855303,0.000498926332937811,0.165458883776434,0.0565565738614754,0.00106294680997165,0.00247840641808945,0.727431889215561,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0,0.00167236193574396,0.848665421605967,0.144098339320739,0.00370843762360476,0.00185543951394526,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0297656858896609,0.000244336475601744,0.00951547807887942,0.00817695885320599,0.000472306069630483,0.00458791238707824,0.947237322245943,0.549425262386022,0.549425262386022,-0.2550541831588352
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0,0.00411439872497652,0.670601694270008,0.311096989874152,0.00850379747404768,0.00568311965681539,0.0,0.0620258136097327,0.0620258136097327,-0.6334414105302022
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.311727053457954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.00523681863830338,0.000823668079767528,0.00977318183991921,0.0124596675509096,0.00267973433328739,0.00363617950788083,0.965390750049932,0.316498770359056,0.316498770359056,-0.5874950507095055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.0,0.010109099822305,0.45796731805265,0.507501663530466,0.0194068402228631,0.00501507837171616,0.0,0.0817828774610745,0.0817828774610745,-0.5807198479650095
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.590361070334383,0.00631834763893091,0.000504819647616299,0.140779687268235,0.0297514168337676,0.000617892126006545,0.0011394500617625,0.820888386423681,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.590361070334383,0.0,0.00283873189227405,0.901276452952094,0.0938738308613158,0.00141019974741145,0.000600784546904834,0.0,1.0,1.0,1.8695349995476385
O=C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)[C@H](C)N(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.63651378,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.442651256490317,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.530769863411841,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)CN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.88045619,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.48874872297084,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)CN(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.83327693,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.343844382133684,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.53889564,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.301494223781961,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0159262664008309,0.00726471746994425,0.0644691443511897,0.0154248397225439,0.00666778094817397,0.00618426236554005,0.884062988741777,0.163983867672707,0.163983867672707,-0.8051696746745034
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0,0.0110768066820314,0.679238145596264,0.289982439081482,0.0151104362851107,0.00459217235511197,0.0,0.0864824917721372,0.0864824917721372,-0.5681789657875123
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.285378059618076,0.00952025723585679,0.00424787112198889,0.0270494802958792,0.00951147065788185,0.00569809581675416,0.00864159943836194,0.935331225433277,0.22281247574214,0.22281247574214,-0.7212074197450102
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.285378059618076,0.0,0.00577401787332259,0.781123329740865,0.202386288853494,0.00852464019685452,0.00219172333546338,0.0,0.23688698835255,0.23688698835255,-0.16682580237138014
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0307690543253117,0.000803846893528031,0.00327375890943859,0.00440309874760962,0.00131506681420977,0.00341198428561488,0.956023190024287,1.14370500641117,1.14370500641117,0.5931227328814345
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0,0.0103006057269574,0.229208194092422,0.735779643429865,0.0182228400970524,0.00648871665370264,0.0,0.146101132843469,0.146101132843469,-0.40908711190961344
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.573885895948325,0.00305704097815131,0.00100491779320209,0.0165773259574103,0.0117710271412967,0.00208697129856503,0.00287252217431477,0.96263019465706,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.573885895948325,0.0,0.00330040832612047,0.545398801975274,0.446192251044312,0.00323782528214899,0.00187071337214386,0.0,1.0,1.0,1.8695349995476385
O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.79756457,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.789042318607025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.40770989,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.168208681201016,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.93089479,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.697749367281184,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.38737682,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.2112383136936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.27999390910873,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.611152257665639,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.1422481808981475,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.515354881665727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.57532934397707,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.451896454476337,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9250774057346085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.829912458665998,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421728001525434,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.775756486563625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.862341963516347,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.55042057,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,5.550631295162026,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.34229222,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.47597224751641,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.30473405,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.563722996073918,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O,DSPC,0,0,1,0,16.11614863,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.275554390163364,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O,DSPC,0,0,1,0,16.80938411,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.35709336812867,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.32727581,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.473579765600494,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,17.03239796,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.5612182984589085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.71577453,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.695924549256556,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.72351388,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.857484114602081,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.6246954,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.483228515182849,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O,DSPC,0,0,1,0,16.38850868,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.426521874560432,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O,DSPC,0,0,1,0,17.04402965,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.412919498116252,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.53558149,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.69866052907543,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.95535314,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.9459189793765646,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.450269224770129,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.46731585,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.659658371272161,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.8769168,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.139321635057579,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.04309994,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.283448621312786,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O,DSPC,0,0,1,0,17.76093253,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1455128487965,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,18.07661492,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.3551691805039985,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.632923618509176,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-],DSPC,0,0,1,0,12.69438691,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TEA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.762173934797756,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0111914004572023,0.00227125491616379,0.00877931935589419,0.0082437061808303,0.00401873844514775,0.00849693826019724,0.956998642384564,0.596141429580998,0.596141429580998,-0.18837922911736
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0,0.00531733106486159,0.69156525750989,0.28508003495893,0.0160312488066627,0.00200612765965623,0.0,0.176602424488684,0.176602424488684,-0.3276946657499996
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0210584248832937,0.000931640117614886,0.0300315170504259,0.0160360600660287,0.002060495753182,0.00519348457253804,0.924688377556917,0.507741968135695,0.507741968135695,-0.31454604422779553
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0,0.00533934786984105,0.597844801683409,0.374278985337898,0.0199301473078145,0.00260671780103763,0.0,0.177860137006811,0.177860137006811,-0.3243384702286213
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.664405571096625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.498141613229568,0.00224222740615835,0.000962422246665562,0.00287219892799367,0.00322451176864607,0.00206661890626862,0.00333409585594076,0.985297924888327,0.792858557060483,0.792858557060483,0.0923823620278189
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.498141613229568,0.0,0.00657230701947091,0.556297397905001,0.404138164228711,0.0296624454205942,0.00332968542622302,0.0,0.20948041157182,0.20948041157182,-0.2399600273409918
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.462799844696364,0.0122002332749747,0.000591091003585345,0.00113975593374826,0.00176766182040017,0.00118628775621157,0.000814512180559894,0.98230045803052,1.58712844716331,1.58712844716331,1.2259922362734261
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.462799844696364,0.0,0.0055909076747788,0.864547542326111,0.121503978921508,0.00729914012568763,0.00105843095191469,0.0,0.762385942529413,0.762385942529413,1.2354638394013375
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0390763854278316,0.00164994009844252,0.0661192424915616,0.0206209930549816,0.00197347693054232,0.00160454285244798,0.868955419144192,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0,0.00384316363496011,0.851255867494199,0.137210400166604,0.00701109092659647,0.000679477777641109,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.67788651,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.401951803481151,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCCC)OCCCCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)CO)=O,DSPC,0,0,1,0,17.86915095,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421487703554795,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O,DSPC,0,0,1,0,17.61285873,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.577593418217857,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCCC(OCCCCCCCCC)=O,DSPC,0,0,1,0,15.66191374,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DBU,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.647271362006727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.541058240520847,0.0155523974922323,0.00129152518305059,0.446962380102849,0.0407067099579296,0.00170625578284345,0.00421830607343662,0.489562425407659,1.0,4.04718291807415,4.73706835052163
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.83323084,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.1751562049585145,0.127270779777207,0.0355651632001246,0.0965373529640882,0.0454740204097531,0.0338026797538366,0.0465840928565864,0.614765911038405,0.0505010966098528,0.0505010966098528,-0.9671362699547936
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.95682792,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.416186486320586,0.0275897803818406,0.0140220813902507,0.0611423332934752,0.0248626002542061,0.0133347505104052,0.0187510241318683,0.840297430037954,0.11103838626238,0.11103838626238,-0.8807353246775064
C=CCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)=O,DSPC,0,0,1,0,18.01719192,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.445588116163626,0.0250376334304389,0.00337885545037859,0.0517009582142691,0.0430146012578083,0.00350252056656834,0.00406753936383155,0.869297891716705,0.594087846809013,0.594087846809013,-0.19131017455153912
CCCCCCCCCCCC(OCCCCCCN(CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.28161356,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.381026134340298,0.00774884428490629,0.00205921183588078,0.0366644403250292,0.0113925424121347,0.00225130046176364,0.00414541402825956,0.935738246652026,0.903691788703443,0.903691788703443,0.2505674416217897
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.382151626862033,0.0281381236661192,0.00268792352252722,0.218417144486954,0.0369503427520482,0.00199553488006137,0.00289937744032574,0.708911553251965,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.83044719,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.199605072879593,0.0747106900577881,0.0465999615731367,0.107994265529626,0.0501322770872438,0.0448116344718523,0.0485065251769853,0.627244646103368,0.0685266977729659,0.0685266977729659,-0.9414094990897005
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.94795095,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.333755086000182,0.0109650973341036,0.00500301836333305,0.0209516607489436,0.00928876974106986,0.00498354505150691,0.00613733877720584,0.942670569983837,0.624112412102086,0.624112412102086,-0.14845806079238213
CCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.64728116,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3330989610504576,0.0312031939311219,0.00665572714585857,0.0303955096845431,0.016483404133503,0.00703656560389733,0.0108270584446455,0.897398541056431,0.396247798437663,0.396247798437663,-0.4736744378197291
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.21401022,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,0.0,4.865224091322398,0.113993758795815,0.073640090558649,0.155999510493789,0.089181912745518,0.0778008933488344,0.0854800220277795,0.403903812029615,0.0331042054271613,0.0331042054271613,-0.991965723861604
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.964966,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.177279038170981,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.327834405590455,0.0791681309989092,0.00438236238399703,0.207450725009039,0.0200057324176319,0.00435501692886232,0.00687586277442937,0.677762169487131,1.0,1.0,0.38802190219888055
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.01143435,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.826712455935327,0.051854991416453,0.0528002488161413,0.131177333337399,0.0608349367134925,0.0676316423389937,0.091080124286102,0.544620723091419,0.0058976768275302,0.0058976768275302,-1.0307958367096368
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.98131005,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.613138355637268,0.0349404656939791,0.032170759570341,0.107989787547248,0.0410644871922655,0.0376181677387698,0.0487295770112475,0.697486755246149,0.0093821747742871,0.0093821747742871,-1.025822638898096
O=C([C@H](CO)N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,13.72220648,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.45318382899021,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.27012616,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.256453162449338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.19898065,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.868303385518459,0.0353281775739917,0.00307182736960491,0.034716407488313,0.0124183147896963,0.00493000176115631,0.00714349716206655,0.902391773855171,0.291015633780908,0.291015633780908,-0.6238654779555869
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.260282639765531,0.0263012913083446,0.00104221918552839,0.17396331575752,0.0231252484593015,0.00218421226891195,0.00250493797184971,0.770878775048544,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.400848388914469,0.142104027989206,0.00287714799265922,0.215134204863943,0.0243152184566193,0.00619704480449007,0.00405451457231669,0.605317841320765,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN(CCN(C)CCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.06597416,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3551691805039985,0.0696417285874694,0.0029599268608454,0.0569405498935433,0.0189535946790038,0.00628554949471398,0.00620455647115851,0.839014094013266,1.46543205325214,1.46543205325214,1.0523028700808776
O=C(OCCCCCCN([C@H](C(NCCN(C)CCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.80021894,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3181545580794705,0.0260251149767627,0.00751090805185066,0.0532899531021804,0.0511794000344704,0.0152455710134586,0.0158624088727893,0.830886643948488,0.594741863231617,0.594741863231617,-0.19037673935045565
CCCCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)=O,DSPC,0,0,1,0,17.89376817,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.605170185988091,0.00991904799330563,0.00800736011391533,0.0452217049389508,0.0197202047147262,0.0164331186633441,0.0158205463682553,0.884878017207502,0.0777961107519447,0.0777961107519447,-0.9281798674338029
O=C(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.61561565,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.886582645426277,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN(CCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.01340623,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.190175207928333,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCOCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.7439276,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2694176902912275,0.0273933363293668,0.0025481137083807,0.0489889660247262,0.00910395259986531,0.00553863037137659,0.00570731639004281,0.900719684576242,0.282511511559215,0.282511511559215,-0.6360028597730629
O=C(CCCCCCCCCCC)OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.18802872,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.561949483533528,0.0107761878140537,0.0018907931479914,0.00906874325536026,0.00817364202148832,0.00369121050409089,0.00412231341943734,0.962277109837578,1.03869430459932,1.03869430459932,0.44324777229346224
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.8896653,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.422808628394115,0.0,0.00393259539867672,0.698404256940233,0.29082082024119,0.00482745799593445,0.00201486942396601,0.0,0.150267764477171,0.150267764477171,-0.3979684896277195
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.24735173134728,0.0,0.0193985055782088,0.642311593152982,0.297952931923085,0.0232690994142363,0.0170678699314884,0.0,0.0138284395356039,0.0138284395356039,-0.7620557072620823
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.776599301615622,0.0,0.00374237304524464,0.388696129733584,0.542462789676973,0.0600826887673663,0.00501601877683173,0.0,0.0757788640374704,0.0757788640374704,-0.5967415084575073
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.59784341060163,0.0,0.00454633850545055,0.547957057084188,0.42844914578143,0.0150324705651762,0.00401498806375593,0.0,0.0747683143174281,0.0747683143174281,-0.5994381520828621
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,46.5,7.5,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.784988612563927,0.0,0.00648649184357099,0.353238786148937,0.611732175774514,0.0204133713900616,0.00812917484291689,0.0,0.231046253558505,0.231046253558505,-0.18241175518238087
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.684905154006945,0.0,0.00209231248329155,0.858334702447977,0.133879376324869,0.0038743559198132,0.0018192528240494,0.0,1.0,1.0,1.8695349995476385
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)C,DSPC,0,0,1,0,18.00540724,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.583231278469337,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)C,DSPC,0,0,1,0,17.73535311,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.224056168743758,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCC(OCCCCCCN(CCCNC([C@@H](N(CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CO)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)=O)OCCCC(F)(F)F,DSPC,0,0,1,0,18.72527826,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.972587226458725,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.8896653,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.363226005210164,0.0302618004269707,0.0170318389360463,0.0852511261606349,0.0321310738618372,0.020553836096385,0.0249767617646758,0.78979356275345,0.103578477209434,0.103578477209434,-0.8913823687978608
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,17.93964861,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.27430221608671,0.0441668582339066,0.00173504332049564,0.0552287456296669,0.0103338721124601,0.00424436496446174,0.00798306414101548,0.876308051597994,0.118006736161235,0.118006736161235,-0.8707898510406828
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.66483929,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.322011202263895,0.014374943627672,0.00199135248489222,0.0891563599260395,0.0109943655858212,0.00408170887074953,0.00721565797781185,0.872185611527014,0.120117219447052,0.120117219447052,-0.867777695195366
C=CCCCCCCCCC(OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.93091393,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.589955020181611,0.159505299591344,0.00863892692709962,0.059163494819016,0.0251436766117119,0.0207012928199433,0.0319161553971728,0.694931153833713,0.19624671777719,0.19624671777719,-0.7591230022455473
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.461068842013835,0.18227458966528,0.00260059752378256,0.10140002712747,0.0194272464327483,0.00394998811850684,0.00708234329707097,0.683265207835141,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.897839799950911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87291972,32.96703297,21.97802198,43.95604396,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.667205576907544,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.34369997,41.32231405,16.52892562,41.32231405,0.826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.786658062033468,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.12329906,27.02702703,32.43243243,37.83783784,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.520374534283375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.602904588,25.0,40.0,30.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.2162671661789055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.22342652,38.46153846,21.97802198,38.46153846,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.634728988229636,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.21412129,40.0,34.28571429,22.85714286,2.857142857,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.378896741664954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.29890072,34.65346535,39.6039604,24.75247525,0.99009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.661550519424199,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.62419529,41.86046512,37.20930233,18.60465116,2.325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.552612935249416,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,5.021245473208271,0.0189024787568605,0.00542838949966448,0.0161874266221436,0.00564673685028802,0.0063903753402389,0.0111802988958026,0.936264294035002,0.0913658402077254,0.0913658402077254,-0.908812673116613
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.59373115,37.83783784,37.83783784,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.484470400750307,0.220192249542946,0.000764987158036526,0.00117389921248248,0.000355328494502401,0.000727082388944626,0.00146163086877099,0.775324822334317,0.909323670538887,0.909323670538887,0.25860546111465654
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.02523135,35.8974359,41.02564103,20.51282051,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.474947598938117,0.0634606467339624,0.00208550415241484,0.000693953783467295,0.000703971489002912,0.00107462659382075,0.00306678394465369,0.928914513302678,0.68813569412733,0.68813569412733,-0.057081784806354334
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.414493824811383,0.0115671522937999,0.000329262998462127,0.000782715410474643,0.000454168201139608,0.00050928396392566,0.0365052454816706,0.949852171650527,1.45919493888772,1.45919493888772,1.0434010414727322
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.50825332,52.83018868,26.41509434,18.86792453,1.886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573163389853005,0.0289504727873473,0.000587630380490671,0.00098172979734669,0.000247631664832521,0.000530890620697785,0.00148666967519347,0.967214975074092,1.18732779204068,1.18732779204068,0.6553827041429786
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.02959744,50.90909091,29.09090909,18.18181818,1.818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.424367475163407,0.01918176556647,0.0010650954164724,0.0022206234626453,0.00126505200881015,0.0010329415925789,0.00258134917445057,0.972653172778573,0.519739549496667,0.519739549496667,-0.29742267487018065
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.0526464,43.24324324,32.43243243,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.646312129319266,0.0173760673957131,0.000550323482827711,0.00231355504088989,0.000799250291024724,0.00171157517792979,0.00187915335599706,0.975370075255618,0.641975082983608,0.641975082983608,-0.12296382974571453
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87880561,39.02439024,39.02439024,19.51219512,2.43902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.62790967295758,0.031425165165133,0.00121897501467252,0.00336392108926765,0.00273184674446895,0.00365496097119473,0.00253008289994281,0.95507504811532,0.292484943880311,0.292484943880311,-0.6217684269937327
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.72896002,41.02564103,30.76923077,25.64102564,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.6141299273595635,0.00243290161785256,0.00374029360494432,0.00771109158226845,0.00256075951190699,0.0024473081411263,0.00398520450059787,0.977122441041304,0.29000081469118,0.29000081469118,-0.6253138633910964
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2936051730729785,0.0291199872991734,0.000702410023626044,0.0253755412996204,0.0176881988849176,0.000962484515645204,0.00126799370807735,0.92488338426894,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.596835549198033,0.0642873127295256,0.000194616801396495,0.00548703707264694,0.0163820187916684,0.000849254927099769,0.000518055392084143,0.912281704285579,0.772854925639995,0.772854925639995,0.06383247693007311
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.26769266,37.83783784,37.83783784,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.284827171296749,0.000820324065776298,6.77505055763446e-05,0.00130838737685328,0.00203458073148474,0.00044026025400656,0.00179231955954145,0.993536377506761,0.647354606156059,0.647354606156059,-0.11528598539707118
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.69845587,35.8974359,41.02564103,20.51282051,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.355939299910563,0.000606683031689403,0.000350488437662207,0.00200552330636915,0.00341592792036262,0.00135658595795651,0.00484812686613966,0.98741666447982,0.429472560198128,0.429472560198128,-0.42625489130230415
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.73864775,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.210051369934071,0.0506054803736383,0.000934742670841204,0.00195746112246746,0.00131704918881155,0.00229254534633995,0.00362188526923176,0.93927083602867,0.295296757118666,0.295296757118666,-0.6177553084162161
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.22254695,52.83018868,26.41509434,18.86792453,1.886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.19614876167715,0.000394517913167851,0.000925918583325644,0.00219111536287718,0.00192843383777798,0.00141208216065332,0.00279803133939282,0.990349900802805,0.423957111788814,0.423957111788814,-0.43412673292138043
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.73562869,50.90909091,29.09090909,18.18181818,1.818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.324000197151533,0.0149763371723649,9.09516394922477e-05,0.00865819492777344,0.00337158611087041,0.000870833891384162,0.00234291805381448,0.9696891782043,0.799987755503576,0.799987755503576,0.10255740435442702
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.73441264,43.24324324,32.43243243,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.638604962074329,0.00412763242238728,0.000587351434637121,0.00125519721482213,0.00156835329887146,0.00151910105091065,0.00332452673735467,0.987617837841017,0.519710678404319,0.519710678404319,-0.29746388070685387
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.55362203,39.02439024,39.02439024,19.51219512,2.43902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.465448242812954,0.001908149535057,0.00051106883667359,0.00195557181028906,0.00222543526142979,0.00102554934782431,0.0036709617373884,0.988703263471338,0.559906246507883,0.559906246507883,-0.24009535462913364
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.4082575,41.02564103,30.76923077,25.64102564,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.439351701293151,0.0164941051995163,0.00133624924425635,0.0136411729141475,0.0068725438331318,0.00281561744256348,0.00565863059250302,0.953181680773882,0.404416041627467,0.404416041627467,-0.4620164343493942
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.348211286179151,0.25310386523031,0.000588156076259717,0.140706646889545,0.17621759673582,0.00218337900345845,0.000839731767209391,0.426360624297398,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.574298522321004,0.0173152888243317,0.00170643426094864,0.0181271736370668,0.0103847448319841,0.00234708518590686,0.00464250497463967,0.945476768285122,0.880302275630684,0.880302275630684,0.21718510735044552
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.54771521,32.96703297,21.97802198,43.95604396,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5300155123873305,0.0022188818222417,0.00151967168045253,0.0265741083102934,0.00935341146520975,0.00161955884356527,0.00594450434134348,0.952769863536894,0.693395601815244,0.693395601815244,-0.0495746598769834
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.03951812,41.32231405,16.52892562,41.32231405,0.826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.640537329825382,0.0191565810814788,0.00120917820488213,0.00564887782228727,0.00368324602436162,0.00270413188019715,0.00625226385441887,0.961345721132374,0.702078866162311,0.702078866162311,-0.037181600128431615
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,10.8033785,27.02702703,32.43243243,37.83783784,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.2431955089544555,0.0191175904912105,0.0046774627841674,0.0253721583259607,0.0153479247605493,0.0105242912643767,0.0240873946993884,0.900873177674347,0.168910555827937,0.168910555827937,-0.7981381323616322
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,9.298704135,25.0,40.0,30.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.822697998516666,0.00783638212803346,0.00315432464612104,0.0156004284210389,0.0122536904537434,0.00649575798551451,0.014293561001533,0.940365855364016,0.26946434750834,0.26946434750834,-0.6546242303969191
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.90666525,38.46153846,21.97802198,38.46153846,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.291292751611072,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.89035919,40.0,34.28571429,22.85714286,2.857142857,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.388753955423308,0.0457836478243602,0.00256820195313693,0.0933595380902435,0.040121791020458,0.00303459231576053,0.00719748271402532,0.807934746082015,0.638042293066864,0.638042293066864,-0.12857684559650717
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.97231927,34.65346535,39.6039604,24.75247525,0.99009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.500031867864786,0.00367784574047392,0.00111977791364668,0.0109807451773001,0.00533981749985873,0.0035253353907892,0.00945759694134628,0.965898881336585,0.664597706735618,0.664597706735618,-0.09067602683869287
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.30278396,41.86046512,37.20930233,18.60465116,2.325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.578518154990665,0.00602415700375336,0.00352191807012307,0.0129438874596237,0.0112365957475355,0.00705054455561779,0.0163551166761144,0.942867780487232,0.387412476367661,0.387412476367661,-0.486284519689253
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DOPE,1,0,0,0,14.78083639,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.373742415086184,0.00132025329631253,0.000860633620224201,0.00503931327076771,0.0029913613071963,0.00270028184029275,0.0088532339643477,0.978234922700859,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.434619084793052,0.00770185399584477,0.00244833711322221,0.0462111239750686,0.0198642411939162,0.00381226904350308,0.00922041774380283,0.910741756934642,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,11.7812451,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.485936098064393,0.00448668985970796,0.00155299888410839,0.00808200908228358,0.00771278024096098,0.00385266053622471,0.00536687174407294,0.968945989652641,1.22295554827804,1.22295554827804,0.7062318887477964
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.73444252169223,0.00221922165343577,0.00134658478491355,0.00928071520245763,0.0103471897935628,0.00308928870366618,0.00305991935175966,0.970657080510204,2.4848301850992,2.4848301850992,2.507223675274371
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.7140245909001735,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.85564,30.9,36.3,25.9,6.9,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.002960000420248,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.10629825,33.7,32.2,28.8,5.4,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,3.9917579734469992,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.076607527,21.5,44.3,27.4,6.7,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.150252194160396,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.262126773,28.5,36.9,23.3,11.4,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,3.938470175442994,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.14390228,47.0,40.4,5.7,6.8,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.139158578011893,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.465333240800292,0.0929588198875335,0.00109661539851913,0.0103406974639253,0.00262333547972377,0.00257373980843396,0.00319533888859958,0.887211453073265,2.49616154919077,2.49616154919077,2.5233961959539766
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,41.0,39.5,16.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.25063580654847,0.00217929592656579,0.00233573351378476,0.00718449647353577,0.00718369422949875,0.00471157922942054,0.00408542775852615,0.972319772868668,1.71461830076508,1.71461830076508,1.4079502315467747
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.40653622,31.3333,31.3333,31.3333,6.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.188896879163323,0.0142737392382439,0.00348189340868737,0.00880858320276677,0.0038525568856599,0.00593274588142816,0.00610316587084082,0.957547315512373,0.645718762121967,0.645718762121967,-0.11762071943757772
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,50.0,23.5,23.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.343935283551159,0.0065593281978378,0.00138907609400551,0.00613919753007927,0.00613411120238244,0.00366825953495706,0.00406194129869205,0.972048086142046,1.35219591573978,1.35219591573978,0.890688278863242
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.200348974,22.0,22.0,50.0,6.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.057161771094385,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.72417162,27.0,27.0,41.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.102973888920155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.092439729,16.0,39.5,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.127940511650616,0.0097349353786325,0.00823434520879355,0.0380775286515883,0.0189007253206434,0.0281939358827934,0.0273826912679074,0.869475838289641,0.161929321885153,0.161929321885153,-0.8081019945583146
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,39.5,16.0,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.116269119637892,0.00176070173692806,0.00134882241229812,0.00721447825021801,0.00277771416530431,0.00258248336542972,0.00338400053115958,0.980931799538662,0.834918279031508,0.834918279031508,0.15241147395626697
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.312676556539088,0.0122849683487715,0.00187692747865846,0.313004652084084,0.0267625511357853,0.00478000951875277,0.00400214034383056,0.637288751090117,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5612182984589085,0.00230427148121394,0.00151653786120671,0.00981883965091339,0.0195498469521307,0.00278714514326426,0.00256552165624032,0.961457837255031,3.54213716664653,3.54213716664653,4.0162493217529285
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,41.0,39.5,16.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.2756934238792645,0.00339636246099529,0.00439836397767252,0.00922438120812044,0.0070906355917358,0.00777777401057153,0.0070228258793507,0.961089656871554,1.60048193764837,1.60048193764837,1.2450508067393784
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,50.0,23.5,23.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.300138475201197,0.0251900613139205,0.0263858529561065,0.0690244086529141,0.0290319859464883,0.0512059292322219,0.0395084822769767,0.759653279621372,0.244442812501583,0.244442812501583,-0.6903358436733202
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,39.5,16.0,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.035478809355064,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.314416735011824,0.00832740543716945,0.00279899792781369,0.0133506530995165,0.00590470004845411,0.00800781451355169,0.00611088774111073,0.955499541232384,1.4036171732161,1.4036171732161,0.9640785029516001
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.46964291,32.3,32.3,32.3,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.122932019074013,0.00935369123549862,0.00681432683334856,0.0266295187790274,0.0091342786879667,0.0148394527045059,0.0109795829907811,0.922249148768872,0.807897092094877,0.807897092094877,0.11384588723707807
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.214347354616797,0.00175971204953205,0.0023945553766021,0.00864096914216858,0.00287247113967731,0.00354165273920712,0.00438932700137801,0.976401312551435,2.1807873939408,2.1807873939408,2.073283128685432
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.297557478047431,0.0163588203416613,0.0050349858804786,0.141665503002976,0.0268932928836599,0.0108166459136593,0.00842178986187252,0.790808962115693,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.623991940228679,0.0114998638575461,0.00130788860611426,0.00505223783079306,0.0046933168158669,0.00183202266239377,0.00287251942980201,0.972742150797484,1.19732008331576,1.19732008331576,0.6696440530835793
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.47398367,41.5,40.5,16.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.261975403606051,0.0120973279883405,0.00779128029381303,0.0260350268299895,0.0160802201335602,0.0156019499205845,0.0170739234476819,0.90532027138603,0.213285375768679,0.213285375768679,-0.7348048313269125
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.72570651,40.5,16.0,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.168678699274804,0.00644850088058007,0.00798921970887525,0.0221223520376599,0.0111631004951633,0.0106463671035197,0.00996963598739929,0.931660823786802,0.29077874869216,0.29077874869216,-0.6242035686713655
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.63764671,41.5,40.5,16.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.40562108352751,0.0088141667427258,0.00585903666298478,0.0157870816204507,0.010986042994209,0.00978368783097364,0.0102623946891479,0.938507589459508,0.370029347989408,0.370029347989408,-0.5110943308383519
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.402441819416474,0.154933534385178,0.00229861102597737,0.00525615721273492,0.00408539799683711,0.0022876287732977,0.00287249757879639,0.828266173027179,1.34933481107146,1.34933481107146,0.88660480982624
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.91076362,42.0,40.5,16.5,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.607168188650764,0.0408588610755303,0.0177373482989948,0.0425327283385076,0.0277718677406049,0.0276871974121274,0.0218927074965806,0.821519289637654,0.158736230637426,0.158736230637426,-0.8126592864976097
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.427716760590997,0.00307921600642319,0.00224989559352084,0.00599370029233814,0.00443157985269048,0.00263031532778781,0.00293093049696406,0.978684362430275,1.27822314397057,1.27822314397057,0.785111741784596
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.444179499895966,0.0412236553892641,0.00390663231476925,0.121517080143859,0.0188177267921366,0.00482332620655526,0.0073631886059774,0.802348390547439,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573473099244836,0.00689869445402741,0.00600089779665737,0.0191135089301672,0.00620664286397134,0.00981653359048003,0.0097967903769499,0.942166931987747,0.749333285576466,0.749333285576466,0.030261566378477555
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.88644869,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.688591794127164,0.00886147101476089,0.00436553876298869,0.0150948084008648,0.00476112441477112,0.00826588994437132,0.00836456609804533,0.950286601364198,0.883781845590108,0.883781845590108,0.22215127176544153
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.877221176,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.829113417472866,0.00517423746484337,0.00420818785762778,0.0136338012801862,0.00389526355348657,0.0081026937251479,0.00825574629036951,0.956730069828339,1.02766134878372,1.02766134878372,0.4275011503825392
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4595662121293,0.025369932029363,0.00629969301959379,0.0185849502075566,0.00668329267445478,0.00984673129800659,0.00995848867776924,0.923256912093256,0.773367707896157,0.773367707896157,0.06456433777003012
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.306031912,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.528073135603124,0.00974026247143072,0.00459547921939943,0.0155882894773368,0.00424301614179951,0.00735125258984654,0.00918675243548622,0.949294947664701,0.925634770529548,0.925634770529548,0.28188523570969626
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,6.950074466,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.730921391293651,0.0307398296858454,0.00502448817507942,0.0144391987292623,0.00475975114719379,0.00732990645958348,0.00864531856689022,0.929061507236145,0.282355212986546,0.282355212986546,-0.6362259345836732
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3578620076745835,0.0575651939642587,0.00224327504140443,0.293214190330324,0.103801109257072,0.00316596887134689,0.00243404296405076,0.537576219571543,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1515122352784415,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.2656332579940335,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.431173877940127,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.436396441739405,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.5666372362713075,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.765586907393996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.149936935645806,0.0412282002133458,0.00282906106065428,0.0100452919302821,0.00294646346634102,0.0035555046437446,0.00510039590268196,0.93429508278295,2.31132936702855,2.31132936702855,2.259597216050143
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.244200317766478,0.0307672106546614,0.0492440442693678,0.143087600825361,0.0409904333145751,0.0410729694241231,0.0628737572688051,0.631963984243106,0.159668526820479,0.159668526820479,-0.8113286806519148
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.430459592195471,0.0144382835185698,0.030629687100469,0.0904231657039977,0.0327120644783899,0.0374915496460484,0.0408664371206098,0.753438812431916,0.342029093157046,0.342029093157046,-0.551057277633741
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.560277417097355,0.064087583051715,0.00731756531038673,0.0186036957891068,0.0053871458118381,0.00655845861152129,0.0086069303650773,0.889438621060355,2.14638048731397,2.14638048731397,2.024176383509215
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.667205576907544,0.00310349569550498,0.00416831577034203,0.0115025538737423,0.00349250282837259,0.00500126547712412,0.00690260249517487,0.965829263859739,3.35844880423818,3.35844880423818,3.754082841561727
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.713127327493184,0.00089376253365906,0.00183788568066981,0.0054363636464257,0.00195410248071216,0.00225811087193407,0.00383533887250888,0.98378443591409,3.24722414573894,3.24722414573894,3.595339103815341
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.359653205696989,0.0828383439279835,0.00565653685524585,0.157248489872984,0.00928479521934879,0.00688752099561758,0.00841921269728692,0.729665100431533,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.634728988229636,0.00818072805535472,0.00273349879854757,0.0119346096951512,0.0075308964437597,0.00591367796700706,0.00578329104170321,0.957923297998477,0.213428398303373,0.213428398303373,-0.7346007045438266
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.15051107,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.7140245909001735,0.0160361616147136,0.00185083446366488,0.00730973501824061,0.00349956550575257,0.00416153151105757,0.00426975100661699,0.962872420879954,0.319359456002154,0.319359456002154,-0.5834121797200126
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.327596879,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.822697998516666,0.0208671125611406,0.0200298903914976,0.0765668274895919,0.0297655881927753,0.0442427715485906,0.0417155046265625,0.766812305189841,0.0431568482237034,0.0431568482237034,-0.9776182391106099
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.548282323781043,0.235642631118293,0.00357683071882224,0.268183756367962,0.0537803810677977,0.0056567696761597,0.00550191880428196,0.427657712246684,1.0,1.0,0.38802190219888055
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.41834022,50.0,7.5,41.5,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.892602227184663,0.0004,0.0007,0.8627,0.1335,0.0019,0.0008,0.0,0.33,0.33,0.08164550420240263
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.34376213,50.0,29.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.935911747900319,0.0015,0.0017,0.585,0.3856,0.0215,0.0046,0.0,0.09,0.09,-0.5587925239809655
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.47881241,45.5,7.5,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.657762636107262,0.0008,0.0009,0.9399,0.0565,0.0012,0.0006,0.0,0.26,0.26,-0.10514892068441307
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.58994389,50.0,17.75,30.25,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6520537718869415,0.0009,0.0008,0.8853,0.11,0.0021,0.0009,0.0,0.31,0.31,0.028275668520455245
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.356515817,38.0,30.0,30.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.522874943261261,0.0008,0.0012,0.7508,0.2416,0.0048,0.0008,0.0,0.12,0.12,-0.4787377704580445
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.211083767,38.0,16.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.802380355275797,0.0003,0.0007,0.8979,0.0985,0.0022,0.0005,0.0,0.45,0.45,0.40186451829408665
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.891852481,38.0,23.0,38.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.721173861744397,0.0003,0.0009,0.9061,0.0898,0.0024,0.0005,0.0,0.3,0.3,0.0015907506794815506
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.59856338,45.96,24.83,26.71,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.599152113662528,0.0006,0.0011,0.8386,0.1563,0.0028,0.0007,0.0,0.36,0.36,0.16170025772532357
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.516252746,44.58,19.33,33.08,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.539030383483546,0.0011,0.0009,0.9163,0.0784,0.0025,0.0008,0.0,0.24,0.24,-0.15851875636636045
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.79855736,50.0,7.5,39.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.602165676967792,0.0007,0.0007,0.9622,0.0349,0.001,0.0005,0.0,0.91,0.91,1.6293707389788754
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.789158454,42.5,30.0,24.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.506454213048934,0.0013,0.0022,0.7003,0.2848,0.009,0.0025,0.0,0.1,0.1,-0.5321076061399918
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.924427289,44.71,13.58,39.21,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.543294782270004,0.0006,0.0008,0.9464,0.0496,0.0015,0.0011,0.0,0.56,0.56,0.6953986145447971
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.213203287,41.46,24.83,32.21,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.600157644164547,0.0006,0.0011,0.9277,0.0684,0.0014,0.0008,0.0,0.44,0.44,0.37517960045311294
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.766920469,38.0,14.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.380775852772229,0.0005,0.001,0.9807,0.0157,0.0015,0.0006,0.0,0.46,0.46,0.42854943613506036
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.9150442,50.0,27.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.490881039585964,0.0013,0.001,0.7257,0.2649,0.0061,0.0009,0.0,0.13,0.13,-0.4520528526170708
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.33144164,47.24,11.19,38.87,2.71,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.62790967295758,0.0073,0.0639,0.7768,0.1461,0.0042,0.0016,0.0,1.3,1.3,2.670082534776849
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.92222847,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.8543712716215905,0.001,0.001,0.8647,0.1302,0.0025,0.0007,0.0,0.25,0.25,-0.13183383852538677
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.314817884980432,0.0009,0.0007,0.9116,0.0844,0.0018,0.0006,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.42041204,49.0,7.5,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.534747721691545,0.0013,0.0021,0.5194,0.4632,0.0111,0.0029,0.0,0.5,0.5,0.535289107498955
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,15.70987342,34.25,18.75,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.19116874685764,0.0011,0.0011,0.7685,0.2222,0.0053,0.0018,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,11.2192693,22.0,30.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0028,0.0014,0.4022,0.5806,0.0101,0.003,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.76101632,49.0,28.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.154184562578117,0.001,0.0012,0.5862,0.3912,0.0188,0.0017,0.0,0.16,0.16,-0.37199809909414977
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.31421044,44.61,24.89,27.94,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.155753190350744,0.0041,0.0015,0.5886,0.3825,0.0211,0.0022,0.0,0.13,0.13,-0.4520528526170708
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.60470229,32.11,24.89,40.44,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.104294893075268,0.0017,0.0016,0.5892,0.3913,0.0129,0.0033,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.00750041,49.0,18.75,31.25,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0111,0.0048,0.1796,0.7293,0.0671,0.0082,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.77390107,42.13,18.75,38.13,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.33204826486764,0.0167,0.0049,0.2598,0.6793,0.0289,0.0104,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.21646499,45.61,13.64,38.19,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.365643155423357,0.0042,0.0015,0.3443,0.6172,0.0298,0.003,0.0,0.2,0.2,-0.2652584277302551
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27353562,44.5,7.5,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.436751534363128,0.0067,0.0013,0.5909,0.385,0.0142,0.0019,0.0,0.22,0.22,-0.21188859204830776
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27759176,49.0,30.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0122,0.0028,0.2395,0.6818,0.0594,0.0044,0.0,0.08,0.08,-0.5854774418219391
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.75114553,34.5,30.0,32.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.2484952420493585,0.0029,0.0024,0.3338,0.6429,0.0151,0.0029,0.0,0.07,0.07,-0.6121623596629128
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.61008,39.36,24.89,34.19,1.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.384523514872469,0.0141,0.0106,0.3243,0.5845,0.0592,0.0073,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,12.46688772,24.0,30.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.796616650559046,0.0064,0.0026,0.3777,0.6006,0.0093,0.0034,0.0,0.1,0.1,-0.5321076061399918
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,46.5,7.5,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0024,0.0028,0.4642,0.5174,0.0093,0.0039,0.0,0.81,0.81,1.362521560569139
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.04448224,37.36,29.94,31.71,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.370712874773608,0.033,0.008,0.1094,0.8115,0.0325,0.0056,0.0,0.11,0.11,-0.5054226882990182
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.623010104116422,0.0087,0.0033,0.2348,0.7393,0.011,0.003,0.0,0.36,0.36,0.16170025772532357
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.375757021660286,0.0019,0.0023,0.9077,0.0818,0.0033,0.003,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.34776106,49.0,7.5,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.943782987108415,0.0542,0.0001,0.3146,0.0378,0.0014,0.0006,0.5913,1.14,1.14,0.5878348176473546
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.630330503,34.25,18.75,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.395682961121367,0.03,0.0006,0.0837,0.0261,0.002,0.0013,0.8563,0.78,0.78,0.07403017792270697
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,5.746375559,22.0,30.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.264087336809195,0.0156,0.0014,0.0138,0.0104,0.0025,0.0031,0.9532,0.32,0.32,-0.5824979728365652
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.15734025,49.0,28.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.513054897080286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.812051718,44.61,24.89,27.94,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.470495282661489,0.009,0.0004,0.0178,0.0948,0.0017,0.0003,0.8762,1.05,1.05,0.45938365771619283
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,7.893697629,32.11,24.89,40.44,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.289088639014612,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,0.46,0.46,-0.38268505738809105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.08675917,49.0,18.75,31.25,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9684234452869465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.13512977,42.13,18.75,38.13,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.906015244966153,0.0128,0.0,0.028,0.0208,0.0006,0.0,0.9378,0.93,0.93,0.28811544447464355
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.43848511,45.61,13.64,38.19,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.525044141508806,0.0635,0.0002,0.2019,0.083,0.0009,0.0003,0.6502,1.5,1.5,1.1016394573720025
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.44748395,44.5,7.5,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4520190064939165,0.011,0.0005,0.3972,0.0536,0.0016,0.0009,0.5352,1.45,1.45,1.0302777018546903
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.57169095,49.0,30.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.868303385518459,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.009941019,34.5,30.0,32.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3476939555933765,0.0165,0.0,0.0427,0.0616,0.0035,0.0028,0.8728,0.42,0.42,-0.43977446180194085
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.301142352,39.36,24.89,34.19,1.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.629862798578463,0.0246,0.0,0.1245,0.0895,0.0015,0.0023,0.7576,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,6.525773643,24.0,30.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.732683506287051,0.006,0.0012,0.0205,0.0177,0.0008,0.0,0.9538,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.31765932,46.5,7.5,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.813809051099419,0.073,0.0,0.0373,0.0149,0.0,0.0,0.8748,1.01,1.01,0.40229425330234303
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.01888288,46.37,7.5,44.21,1.92,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.706823839714591,0.0145,0.0004,0.1165,0.019,0.0007,0.0011,0.8477,1.94,1.94,1.7296229059243498
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.30562834,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.73795129722191,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,1.9,1.9,1.6725335015104998
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,9.480986593,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.302712827954156,0.0455,0.0,0.324,0.073,0.0011,0.0012,0.5551,1.0,1.0,0.38802190219888055
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0253701689981931,0.00985209592098701,0.307949537646453,0.622300893638244,0.0174680522283724,0.0170592515677505,0.0,0.0,,
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584559232083967,0.00894763570081526,0.00182903773179144,0.430416319953847,0.549730482792046,0.00757886856613304,0.0014976552553668,0.0,0.0019532059842532,0.0019532059842532,-0.793744670428099
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.5827200571505,0.00757568328250189,0.00220510873539676,0.728025615125869,0.236446776884745,0.0226429923353559,0.00310382363613184,0.0,0.0011482099710543,0.0011482099710543,-0.7958927956755514
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.688867745009658,0.00599960547383456,0.00187471922407934,0.58725363712808,0.393842224090862,0.00908706069367491,0.00194275338946932,0.0,0.0005585876781053,0.0005585876781053,-0.7974661979200065
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0207124354254999,0.00767807173489595,0.560331852523788,0.3797189836544,0.0206003960524344,0.0109582606089812,0.0,0.0001489580680618,0.0001489580680618,-0.7985592911689305
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0084525958204246,0.00170600389954699,0.807774257087237,0.172171860632781,0.00851123850670424,0.00138404405330582,0.0,0.0052460712339961,0.0052460712339961,-0.7849576865630203
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0142965461163966,0.00273099369058116,0.2951874813445,0.196790510597468,0.00567584660232592,0.00900724719724339,0.476311374451485,0.0033203605888808,0.0033203605888808,-1.0344742729359027
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584559232083967,0.0426258503334726,0.000887127042175757,0.102099604743599,0.057196348771858,0.00222434780081794,0.00162961025671667,0.79333711105136,0.0465195426566469,0.0465195426566469,-0.972818883550547
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.5827200571505,0.0182648912592805,0.000462867676668248,0.083073077462289,0.0429608616930204,0.00195825764287227,0.000923423624969053,0.852356620640901,0.0509209522037464,0.0509209522037464,-0.9665370373099135
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.688867745009658,0.0068908069603713,0.000629547873998548,0.021394314943629,0.042448777163022,0.00198708372142952,0.00248444060475972,0.92416502873279,0.016201262972428,0.016201262972428,-1.0160901968011615
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0116932676375475,0.00103739027764326,0.0525071135910941,0.0215477599193875,0.00368874758435242,0.00400972460855577,0.905515996381419,0.006104461793755,0.006104461793755,-1.0305007059455489
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0237911981258413,0.00067207203055979,0.18334881014348,0.0466442684044473,0.00188246389345958,0.000953648344707904,0.742707539057504,0.0550488822731985,0.0550488822731985,-0.9606455105817374
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.572543683160998,0.000714997259249526,0.000661552142657172,0.125943320778554,0.801966162874089,0.0693146503097598,0.00139931663568972,0.0,0.0127373438778132,0.0127373438778132,-0.764967287060561
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.358502089626924,0.00147233862420237,0.00107405472963131,0.901430168335102,0.0923159134092667,0.00310160866776492,0.000605916234032228,0.0,0.0763434621140544,0.0763434621140544,-0.5952348831288257
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.3962992939606,0.00110223184180453,0.00161797426133587,0.963322201717795,0.0321995776177804,0.00129202117564397,0.000465993385639812,0.0,0.380376087923258,0.380376087923258,0.21607368094058316
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.351438552905858,0.00061802522712851,0.00208191419961706,0.00520107649990865,0.018780252186508,0.966671145724669,0.00664758616216931,0.0,0.0289886812604962,0.0289886812604962,-0.7216007267742771
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.544995462952021,0.00423798522906651,0.00360605985882706,0.0132163308359338,0.182768863634774,0.789078621894797,0.00709213854660109,0.0,0.0033387326299993,0.0033387326299993,-0.7900474039572776
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0123483310685072,0.00430719249252366,0.0429874465070588,0.751978605237179,0.174073814828135,0.0143046098665965,0.0,0.0005090956767902,0.0005090956767902,-0.7975982669188943
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.790487251761844,0.00153513483125764,0.00147931904743739,0.82338319944907,0.169033483447006,0.00378262362292623,0.000786239602302501,0.0,0.306009500746919,0.306009500746919,0.017627054049161966
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.842058839093973,0.00164287085070931,0.000659195379539964,0.94017588697419,0.0550751037989028,0.00183173459161262,0.000615208405045708,0.0,0.504231824712829,0.504231824712829,0.5465816969768794
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.572543683160998,0.0204881792124896,0.00996076677576078,0.024515683125648,0.0206076067733214,0.0213656753332114,0.0146396167476402,0.888422472031929,0.0035574041476412,0.0035574041476412,-1.0341359560461585
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.358502089626924,0.0789442718629389,0.000859220559164078,0.352513414289749,0.0167725689541561,0.00207992092629201,0.000939235620822743,0.547891367786878,0.128034152082589,0.128034152082589,-0.8564783709716817
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3962992939606,0.020589791219893,0.00221295822133462,0.77006639472807,0.0336156368936998,0.00141982059640497,0.000804331444027444,0.17129106689657,0.352623838360951,0.352623838360951,-0.5359360852935553
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,1.0,4.351438552905858,0.0518701933925729,0.031230151711712,0.196119602463562,0.0891250765615729,0.225998436967717,0.183312147304902,0.222344391597961,0.0006916766953858,0.0006916766953858,-1.0382260228827003
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.544995462952021,0.0318134391856252,0.0195739470918212,0.0658637908929555,0.0405146823853727,0.0383355214778253,0.0445803960220688,0.759318222944331,0.0007826107131428,0.0007826107131428,-1.0380962386598327
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0496007240706346,0.0248050760368446,0.125156740550784,0.0913290655906173,0.0605654916232193,0.0647609529825488,0.583781949145352,0.000319594239126,0.000319594239126,-1.0387570720282182
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.790487251761844,0.0660465509749711,0.000704686244275338,0.176882938102508,0.134254150019803,0.00301700767902668,0.00146559050061717,0.617629076478799,0.391796497651864,0.391796497651864,-0.4800274905879333
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.842058839093973,0.180962520579808,0.000840183131263393,0.0600498448220066,0.0139903797423045,0.00230022430813273,0.00221494849849946,0.739641898917986,0.515169720881209,0.515169720881209,-0.3039448947184272
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.48897339158558,0.000136174132145422,0.00212452688507234,0.811633900204502,0.179761878637886,0.00385751556458306,0.00248600457581157,0.0,0.767759892635294,0.767759892635294,1.24980418110703
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.675628649636653,0.00268100351583557,0.00240431632025112,0.142040711181502,0.523320437165769,0.324868931367264,0.00468460044937817,0.0,0.0241897161135915,0.0241897161135915,-0.7344067258409619
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.737600973168581,0.00157432110064945,0.00176844882817444,0.053765469363115,0.438156626388713,0.500533090562106,0.00420204375724176,0.0,0.0189624719731265,0.0189624719731265,-0.7483555838832638
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.48897339158558,0.0550309639531662,0.00234353835896855,0.320198252727196,0.282656133384496,0.0064798077198827,0.00202476215621646,0.331266541700075,1.20135127285815,1.20135127285815,0.6753975083349388
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.675628649636653,0.0418659426619505,0.0219153925677162,0.21668759621254,0.199875450362037,0.113029824089051,0.0495629458661235,0.357062848240582,0.0027707272238572,0.0027707272238572,-1.035258728972282
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.737600973168581,0.0234118812216689,0.0071462713755353,0.0426958781226752,0.0464078935005845,0.0346044033846598,0.0235967118628926,0.822136960531984,0.0055457738057274,0.0055457738057274,-1.0312980850577906
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00767358537807448,0.00233215653996207,0.0713684727707158,0.307444763898641,0.0172788380976704,0.00511228295653041,0.588789900358405,0.0063917829512014,0.0063917829512014,-1.0300906311016962
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.579236803961587,0.00833063062779389,0.00173987762429209,0.156651961849343,0.112205138324295,0.00895304009765426,0.00427289873828259,0.707846452738339,0.269390835357988,0.269390835357988,-0.6547291495189385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0158311033527607,0.00109353847138243,0.0200990623529318,0.00589717673503959,0.00332080816189693,0.00297802720282806,0.95078028372316,0.0070114291767852,0.0070114291767852,-1.0292062502525494
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,5.0755487449389,0.0138253404297663,0.00670375922221507,0.064918033729737,0.0310082272870404,0.0307691214666871,0.0156091189056244,0.83716639895893,0.0111434256880136,0.0111434256880136,-1.023308919755896
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.40280917385641,0.0144051248882893,0.000525788660297221,0.125667067331117,0.214373546599095,0.00410880851120861,0.00177167337754258,0.639147990632451,0.176512628889736,0.176512628889736,-0.7872881867764152
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00115119797114568,0.0003959818507672,0.0538124209539168,0.93604524664705,0.00736502972190904,0.00123012285521143,0.0,0.0261518819859255,0.0261518819859255,-0.7291707023316024
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.579236803961587,0.0010942059599737,0.000714578151988552,0.367034511120116,0.62078160479883,0.0079478856978032,0.00242721427128835,0.0,0.970510173989973,0.970510173989973,1.7908416411254202
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0376230130625874,0.00236009027623813,0.247039705692743,0.697452972603375,0.0104681865382628,0.00505603182679352,0.0,0.0013884403431976,0.0013884403431976,-0.7952517429011965
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,5.0755487449389,0.00873826813676438,0.00145112475939544,0.193065080283125,0.778197018798523,0.014433213681334,0.00411529434085825,0.0,0.165721665234437,0.165721665234437,-0.35672988242469916
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.40280917385641,0.00532422079532615,0.00061084449763591,0.522469676271313,0.459778984209221,0.00966894873803684,0.00214732548846694,0.0,0.161020662402855,0.161020662402855,-0.3692744698577941
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584763376210429,0.0318391346416656,0.000341552225113717,0.113678281409446,0.242279767731552,0.00387550619454475,0.000871625110337537,0.60711413268734,0.649833386251602,0.649833386251602,-0.11174818341388475
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.746322465743975,0.0548193142492001,0.000263362025026913,0.0902956804122817,0.160837629010128,0.00315355508353847,0.000739500993108033,0.689890958226717,1.16375238999006,1.16375238999006,0.6217350625958049
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.651385609785054,0.0172566765287249,0.00318344365411915,0.0712890876960715,0.171965068058214,0.0218135302099503,0.0115493777455846,0.702942816107335,0.00327405282427,0.00327405282427,-1.0345403650034368
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584763376210429,0.000599963927151076,0.000397997752734626,0.420976508827142,0.560178394908249,0.017044159994242,0.000802974590480822,0.0,0.25255828640642,0.25255828640642,-0.1250070722684871
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.746322465743975,0.000524374578838527,0.00061514916196369,0.547432124587029,0.435435317287124,0.015309113403191,0.000683920981854007,0.0,0.568394489552276,0.568394489552276,0.7177992409467366
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.651385609785054,0.00171983501988967,0.00189561016704693,0.0120716635806003,0.711278646835123,0.270438826106656,0.00259541829068387,0.0,0.0112897234542117,0.0112897234542117,-0.7688302502674332
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0047850951415261,0.000675911772575438,0.46069265034102,0.522359359837259,0.0109775121699624,0.00050947073765779,0.0,0.773205414607926,0.773205414607926,1.2643355117511204
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.633757642840004,0.00198911414189635,0.00126811595413123,0.543867583730296,0.438842770521552,0.0129988635137729,0.00103355213835123,0.0,1.98493053910539,1.98493053910539,4.497814051056962
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.609759638321899,0.00125031423153586,0.0004860362025215,0.538249539726811,0.445414640899446,0.0137801694455006,0.000819299494184621,0.0,0.291137444797345,0.291137444797345,-0.022058905064912687
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.392884144674663,0.00226285185388551,0.000562872305858137,0.731364439797527,0.256932619347553,0.00825451238600619,0.000622704309170273,0.0,1.82872279459479,1.82872279459479,4.080974968218046
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0442923458834068,0.00055452650331333,0.106459881295074,0.192526940733964,0.00311682882196998,0.000623042068808978,0.652426434693463,0.672431538902446,0.672431538902446,-0.07949530652163618
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.633757642840004,0.0374610013402809,0.0005350551106764,0.260855439538844,0.469905543128085,0.00469334055693451,0.000912093945676405,0.225637526379503,1.69276100831231,1.69276100831231,1.3767547363410753
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.609759638321899,0.0836645231428707,0.000419599806684375,0.0235684307001288,0.0712275212970175,0.00119681308497475,0.00178295859414992,0.818140153374174,0.426058290183635,0.426058290183635,-0.431127857343191
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.392884144674663,0.0512990735432809,0.000672189655491244,0.187343972483681,0.232187436433234,0.00314791870850824,0.00146679734452725,0.523882611831278,1.30784095113947,1.30784095113947,0.8273833160675146
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,17.78759767,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.751259891859986,0.00405799702984203,0.00225047224182105,0.719270208750414,0.257208699720685,0.0138718178214465,0.00334080443579049,0.0,1.25160610942024,1.25160610942024,2.540943835364252
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.666265285347902,0.00272982965803786,0.000172365352517303,0.498048022051036,0.479137442306018,0.0180316959727267,0.00188064465966415,0.0,0.155537169131505,0.155537169131505,-0.3839071266005448
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.904756125442696,0.00273286200255075,0.00260055069792003,0.431146257918051,0.50349018951458,0.0550138028095967,0.00501633705730229,0.0,0.021985308799366,0.021985308799366,-0.7402891686477768
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.733211535868975,0.00166528576158017,0.000176886038620712,0.205207225042143,0.750916028545382,0.0392720451710516,0.00276252944122191,0.0,0.120096690961961,0.120096690961961,-0.478479751420455
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.858726543710496,0.00383743159330312,0.00248950729214128,0.555903422423481,0.380445635709031,0.0515668712566801,0.00575713172536402,0.0,0.0526538412251038,0.0526538412251038,-0.6584504418393717
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.666265285347902,0.0567289157085495,0.00653348267008008,0.064839577285576,0.335055277453961,0.0144955694225392,0.0143736618741762,0.507973515585118,0.268311366051918,0.268311366051918,-0.6562698060131026
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.904756125442696,0.0248552898268163,0.0125192728735768,0.0725307642598596,0.0355254691282667,0.0214395648154144,0.0248745799236939,0.808255059172372,0.0741845243461588,0.0741845243461588,-0.9333344503561898
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.733211535868975,0.0883917007893502,0.00174599838911923,0.0536405332414895,0.100118671210748,0.00771990063396103,0.00639776118235737,0.741985434552974,0.528035509086713,0.528035509086713,-0.28558239006925334
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.858726543710496,0.0175679405294797,0.00960173891174304,0.0903179131752613,0.0388184937379254,0.0182497546285787,0.0249045868533177,0.800539572163694,0.125181510399577,0.125181510399577,-0.8605497613389135
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.62870578,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.765586907393996,0.00159278655447388,0.00186611160196327,0.488795918944862,0.485247409700546,0.018616198181097,0.00388157501705755,0.0,0.352570746370957,0.352570746370957,0.14187535545424673
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.61880246,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.82374330878754,0.000875415234709484,0.00127375854285246,0.683377837104949,0.304003257921165,0.00820355561270421,0.00226617558361995,0.0,0.943420561172443,0.943420561172443,1.7185532318874628
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.433313679041901,0.000602190120987361,0.000576528881915898,0.00566197423128506,0.0161763859347042,0.971683265119797,0.00529965571131053,0.0,0.0305789310371634,0.0305789310371634,-0.7173571583105779
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.70929826,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.356324137321509,0.00187378052819512,0.00157654975652554,0.0163863796216318,0.0648246159165097,0.905280007427939,0.0100586667491993,0.0,0.003875136361479,0.003875136361479,-0.7886160150068647
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.17273956,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.440767129696481,0.00301049906217731,9.21592223531261e-05,0.00380096827414773,0.0130323481002541,0.97657327492354,0.00349075041752818,0.0,0.0274401441027376,0.0274401441027376,-0.7257329854571254
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.349632566862877,0.00273989274094748,0.00161018393061426,0.0112824839963327,0.0583352940699212,0.919247401685963,0.00678474357622127,0.0,0.0081601896883771,0.0081601896883771,-0.7771813854096181
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.90345652,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.662778498608405,0.00349315451118928,0.00171298178399312,0.037797325974731,0.242816837972913,0.706569889763285,0.00760980999388795,0.0,0.0136767051395404,0.0136767051395404,-0.7624606092513427
O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,0,0,1,,4.405498990859024,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,,4.815106909815019,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.562053894914463,0.00241700650155169,0.00189161759954923,0.0117804592312353,0.0588098364115177,0.918016488291877,0.0070845919642692,0.0,0.288385322760908,0.288385322760908,-0.029402920107978105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.667205576907544,0.00146771264056884,0.000853267380299107,0.00521853383313367,0.0984194458399351,0.890752405611161,0.00328863469490281,0.0,0.174730948641107,0.174730948641107,-0.3326886836733955
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.94799221,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.701389043728634,0.00256320924432886,0.00193796271600952,0.0128146756680969,0.0418402586947232,0.934553052894321,0.00629084078252029,0.0,0.0492674291707299,0.0492674291707299,-0.6674870545840368
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.460491174618648,0.00101051612937229,0.00153512067382825,0.00950098551353592,0.161931963893941,0.822835993399315,0.00318542039000704,0.0,0.105055900803977,0.105055900803977,-0.5186159763833679
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,19.0764718,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.505460341839079,0.00282763425766742,0.00135220428389579,0.101550310310828,0.701364372579719,0.18950529802972,0.00340018053817036,0.0,0.0700302222351868,0.0700302222351868,-0.6120817118766197
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.18453431,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.684905154006945,0.0025903109842197,0.00122267327648511,0.0959380417500791,0.558064631213231,0.339326541744348,0.00285780103163663,0.0,0.0836567108446898,0.0836567108446898,-0.5757195389760648
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.58497913,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.695924549256556,0.00270162630925447,0.000571977156802491,0.072649821877092,0.283620916967858,0.638520904456637,0.00193475323235631,0.0,0.108372702997361,0.108372702997361,-0.5097651169808466
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O,DSPC,0,0,1,0,16.82518306,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,LYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,4.202899968776446,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.52948326,43.25,25.0,30.0,1.75,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,5.029784112935016,0.000951862951033406,0.000642237882584555,0.00747953132811133,0.295137112679544,0.692754163229738,0.0030350919289883,0.0,0.19435393861906,0.19435393861906,-0.2803248961378029
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.10169345,30.0,25.0,42.5,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.833102254034098,0.00529626249319983,0.00246267213977097,0.0289260006923807,0.563065088278535,0.393847703229461,0.00640227316665243,0.0,0.049072760763369,0.049072760763369,-0.6680065256297026
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.72804315,38.075,17.975,41.825,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,,4.930148043183569,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.39261658,37.0,25.0,37.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.146912912388803,0.000759366167023555,0.000694817987152034,0.00466364025695932,0.212680085653105,0.777593147751606,0.00360894218415418,0.0,0.201238755105862,0.201238755105862,-0.2619528199077537
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.51039532,38.5,20.5,38.5,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.684905154006945,0.00157535225652128,0.00592927130077556,0.00900517890128691,0.366135503933579,0.613833328839362,0.00352136476847493,0.0,0.149329656900936,0.149329656900936,-0.40047182198750214
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.48290639,45.0,9.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.869839484130799,0.00147117555088917,0.000927103843315829,0.00585237061645294,0.136146016514374,0.851575135737455,0.00402819773751327,0.0,0.31219703699332,0.31219703699332,0.034138443686487704
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.13138042,41.2,22.35,34.325,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.901564199041894,0.00315707422768752,0.0025689389054212,0.0146712017391132,0.327849346901905,0.646061693847123,0.0056917443787501,0.0,0.158541375998041,0.158541375998041,-0.3758904252594646
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.11942242,41.825,14.975,41.825,1.375,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.039546637590676,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.79492927,45.0,22.5,30.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.9141243937154115,0.00113350028034128,0.000566939752127873,0.00680706926467914,0.502661298625749,0.486733894218144,0.00209729785895866,0.0,0.145448415448628,0.145448415448628,-0.4108288829150842
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,12.55393718,34.325,21.725,41.825,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.814620410170298,0.001692878443667,0.000820135726038303,0.00868136575507882,0.408928448915581,0.577101122031978,0.00277604912765729,0.0,0.113760366510672,0.113760366510672,-0.495388181160095
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.93959861,45.0,7.5,45.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.527640983478854,0.00506334343919377,0.004281344333051,0.0165771717732586,0.226890591170162,0.736348900590883,0.0108386486934518,0.0,0.0547343765642327,0.0547343765642327,-0.6528985503803821
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.59337013,45.0,15.75,37.5,1.75,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.810557015713042,0.00141112235558708,0.000749767156842064,0.00637541161251223,0.138880841494329,0.847648476304751,0.00493438107597822,0.0,0.294154433878409,0.294154433878409,-0.0140080944893819
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.66031337,30.0,24.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.16763904290592,0.00199236267032557,0.000827577235394216,0.008719084857644,0.192132365846187,0.792330257640873,0.0039983517495764,0.0,0.151793984465988,0.151793984465988,-0.3938957841268362
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.66358165,37.5,15.0,45.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.618086411254637,0.00271480786609193,0.00181664538344774,0.00938513027274936,0.132547184736695,0.849509595736892,0.0040266360041233,0.0,0.0950036114384557,0.0950036114384557,-0.5454404279666308
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.26186294,45.0,24.0,30.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.098035484377089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.27611859,45.0,11.382,42.618,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.680277658474896,0.00152924607683628,0.00192508702614222,0.0105762053188716,0.167270255683968,0.810875386281306,0.00782381961287527,0.0,0.278754923842637,0.278754923842637,-0.05510156049896443
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.11001923,45.0,13.445,40.445,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.000999438616070677,0.00125158481927741,0.00771842730472846,0.249469737208587,0.735450494958472,0.00511031709286499,0.0,0.286455906115286,0.286455906115286,-0.03455155257492116
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.85662691,45.0,16.405,37.595,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.00141338619768439,0.00124322063420737,0.0100450891793794,0.235894751086175,0.745556785166654,0.00584676773589971,0.0,0.264336417833639,0.264336417833639,-0.09357722532293417

1 smiles Helper_lipid_ID Helper_lipid_ID_DOPE Helper_lipid_ID_DOTAP Helper_lipid_ID_DSPC Helper_lipid_ID_MDOA Cationic_Lipid_to_mRNA_weight_ratio Cationic_Lipid_Mol_Ratio Phospholipid_Mol_Ratio Cholesterol_Mol_Ratio PEG_Lipid_Mol_Ratio Purity Mix_type Cargo_type Cargo_type_mRNA Cargo_type_pDNA Cargo_type_siRNA Target_or_delivered_gene Model_type Model_type_A549 Model_type_BDMC Model_type_BMDM Model_type_HBEC_ALI Model_type_HEK293T Model_type_HeLa Model_type_IGROV1 Model_type_Mouse Model_type_RAW264p7 Delivery_target Delivery_target_body Delivery_target_dendritic_cell Delivery_target_generic_cell Delivery_target_liver Delivery_target_lung Delivery_target_lung_epithelium Delivery_target_macrophage Delivery_target_muscle Delivery_target_spleen Route_of_administration Route_of_administration_in_vitro Route_of_administration_intramuscular Route_of_administration_intratracheal Route_of_administration_intravenous Batch_or_individual_or_barcoded Batch_or_individual_or_barcoded_Barcoded Batch_or_individual_or_barcoded_Individual Value_name Formulation_ID Cationic_Lipid_Mass_Ratio Phospholipid_Mass_Ratio Cholesterol_Mass_Ratio PEG_Lipid_Mass_Ratio Amine Tail Lipid_name Library_ID Experiment_ID Experimenter_ID Experiment_weight Goal screen_id Source Sample_weight Comment Amine_number Full_SMILES Amine_SMILES Tail_length Num_tails Ketone Isocyanide Is_cyclic Formulation Batch_or_individual Random_id 4CR_Lipid_name Aldehyde Carboxylic_acid Amine_name Tail_name Linker MolWt Tail_count Num tails Common_name Ester Disulfide Total_radiance Form_comment molecular_weight split_name_for_normalization Encapsulation_Efficiency_EE<50 Encapsulation_Efficiency_50<=EE<80 Encapsulation_Efficiency_80<EE<=100 PDI_0_0to0_2 PDI_0_2to0_3 PDI_0_3to0_4 PDI_0_4to0_5 toxic size Biodistribution_lymph_nodes Biodistribution_heart Biodistribution_liver Biodistribution_spleen Biodistribution_lung Biodistribution_kidney Biodistribution_muscle quantified_total_luminescence unnormalized_delivery quantified_delivery
2 O=C(CN(CCCCCCCCCCCC)CCCCCCCCCCCC)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.44559484 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 6.892641641172089 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
3 CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCCCC DSPC 0 0 1 0 15.24245185 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.345103280569283 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
4 O=C(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.2554924 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.310127759130018 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
5 O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O DSPC 0 0 1 0 16.95535314 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.35696520407851 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
6 O=C(CN(CCCCCCCCCC)CCCCCCCCCC)NCCCN(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.51030189 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.175309921045206 4.175309921045205 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
7 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.11860943 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.447697327163527 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
8 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 16.80841018 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.381651564343798 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
9 CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC DSPC 0 0 1 0 14.7769988 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.250350662548819 4.2503506625488185 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
10 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.33731463 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.386765389021055 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
11 O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.55151343 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.391729410135267 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
12 O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.85660447 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.114394528387108 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
13 O=C(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.63293083 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 5.272999558563747 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
14 O=C(CN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O DSPC 0 0 1 0 16.2856483 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.28978103552575 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
15 O=C(CN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)NCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.23582504 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.260615499364025 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
16 O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)CN(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.75702627 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.9788005705762375 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
17 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC DSPC 0 0 1 0 16.47477668 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.68213122712422 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
18 CCCCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 19.33366115 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
19 CCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.98780245 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.9473404437239425 4.947340443723942 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
20 CCCCCCCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CO)=O)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.42695266 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.545101659521972 0.0 0.00318490682025255 0.0608074236431031 0.251089505980848 0.00892095913117615 0.00601048706680474 0.669986717357815 0.0815243428420059 0.0815243428420059 -0.9228588036953479
21 CCCCCCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)=O)CO)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.68206611 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.844974178195408 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
22 O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H]([C@H](O)C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.77114057 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence thr Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.331522502500114 4.331522502500113 0.0 0.0131160505661734 0.0817206877958181 0.209957462105326 0.0363069917919837 0.0161572104727098 0.642741597267989 0.0248953087459781 0.0248953087459781 -1.0036817494221935
23 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4135253017332525 0.0 0.00151329913495755 0.0471551068594211 0.0476760649180962 0.00182335320536251 0.00763287581452213 0.89419930006764 0.35502103370942 0.35502103370942 -0.5325147239258616
24 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.509649984130679 0.0 0.00235961766437825 0.513627015742916 0.0879412499947796 0.00175822838354556 0.00311254749811917 0.391201340716262 1.0 1.0 0.38802190219888055
25 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.496359280129911 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
26 CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC DSPC 0 0 1 0 14.13296737 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.170425586627436 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
27 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.445353484534206 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
28 CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC DSPC 0 0 1 0 15.1299087 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.166510173022286 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
29 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 17.04310679 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.673109168996284 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
30 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC DSPC 0 0 1 0 16.72728505 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.7572902340489245 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
31 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.332573750954351 0.0 0.000230328920605394 0.0259372790881254 0.0734981485145439 0.000576894596302152 0.000867946038939987 0.898889402841483 0.486446282346577 0.486446282346577 -0.34493999468492637
32 O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 18.33700102 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.332573750954351 0.0 0.00183814880222334 0.508470854676458 0.479298868566087 0.00664368457868438 0.00374844337654761 0.0 0.0806697533656258 0.0806697533656258 -0.5836902104683951
33 O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 14.7050121 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.577079305821566 0.0 0.00446051681777838 0.0286140231457339 0.01484311836534 0.00629790100652696 0.01599114503205 0.929793295632571 0.0275210452544693 0.0275210452544693 -0.9999342060867568
34 OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O DSPC 0 0 1 0 14.7050121 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.577079305821566 0.0 0.0104002218216073 0.139229779861971 0.807246421461676 0.041233674188 0.00188990266674509 0.0 0.0040656278842911 0.0040656278842911 -0.7881076899433005
35 O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.11494914 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.7535901911063645 0.0 0.00711911642710361 0.153280595121264 0.136743424441396 0.0628412485834964 0.0734141937722642 0.566601421654476 0.0027486514420013 0.0027486514420013 -1.0352902363032352
36 O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.11494914 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.7535901911063645 0.0 0.106975953776871 0.247623902989694 0.292657465739291 0.229416263063982 0.123326414430162 0.0 0.001042320755636 0.001042320755636 -0.7961753601769197
37 O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC DSPC 0 0 1 0 14.05354178 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.789157022101107 0.0 0.0386975655052687 0.153034034478582 0.0799184464451532 0.0414429326981307 0.0607210626185958 0.626185958254269 0.0073827728841294 0.0073827728841294 -1.0286762554754216
38 O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC DSPC 0 0 1 0 14.05354178 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 1 0 0 0 0.0 4.639571612705423 0.0 0.135531713474282 0.541180183023036 0.178510571158094 0.0949195329757021 0.0498579993688861 0.0 0.004009461265808 0.004009461265808 -0.7882575701032632
39 O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 15.91058453 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.639571612705423 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
40 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.391357962102766 0.0 0.000231298468169262 0.195828728849491 0.0126185833117857 0.000504922171493209 0.00109315352063243 0.789723313678428 1.0 1.0 0.38802190219888055
41 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.391357962102766 0.0 0.00515447939315304 0.962574355010024 0.0304157301451643 0.000918038843316605 0.000937396608342438 0.0 1.0 1.0 1.8695349995476385
42 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.45295097301058 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
43 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 4.45295097301058 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
44 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.508769411701737 0.0963955724315343 0.000259669027359828 0.0209585518067849 0.0324510369422159 0.00191021824445882 0.00526970020363582 0.84275525134401 0.95415067884307 0.95415067884307 0.32258414125816925
45 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.508769411701737 0.0 0.00301852406237983 0.561715155652109 0.427466534539213 0.00675382930885143 0.00104595643744612 0.0 0.469108231863161 0.469108231863161 0.4528546780295592
46 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.424367475163407 0.00431198097235812 0.000818950238891083 0.0696322838846972 0.0220758004851341 0.00177157151502323 0.00255208415951453 0.898837328744382 0.673380628639453 0.673380628639453 -0.07814073232611048
47 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.424367475163407 0.0 0.00336772556852765 0.856457049453334 0.133858740361315 0.00483749939645135 0.00147898522037143 0.0 0.274077344076178 0.274077344076178 -0.06758364367522034
48 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.570475216191205 0.0465123735855303 0.000498926332937811 0.165458883776434 0.0565565738614754 0.00106294680997165 0.00247840641808945 0.727431889215561 1.0 1.0 0.38802190219888055
49 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.570475216191205 0.0 0.00167236193574396 0.848665421605967 0.144098339320739 0.00370843762360476 0.00185543951394526 0.0 1.0 1.0 1.8695349995476385
50 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.570268133978827 0.0297656858896609 0.000244336475601744 0.00951547807887942 0.00817695885320599 0.000472306069630483 0.00458791238707824 0.947237322245943 0.549425262386022 0.549425262386022 -0.2550541831588352
51 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.570268133978827 0.0 0.00411439872497652 0.670601694270008 0.311096989874152 0.00850379747404768 0.00568311965681539 0.0 0.0620258136097327 0.0620258136097327 -0.6334414105302022
52 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.33731463 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
53 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 17.04310679 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.311727053457954 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
54 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.9082333604781745 0.00523681863830338 0.000823668079767528 0.00977318183991921 0.0124596675509096 0.00267973433328739 0.00363617950788083 0.965390750049932 0.316498770359056 0.316498770359056 -0.5874950507095055
55 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.9082333604781745 0.0 0.010109099822305 0.45796731805265 0.507501663530466 0.0194068402228631 0.00501507837171616 0.0 0.0817828774610745 0.0817828774610745 -0.5807198479650095
56 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.590361070334383 0.00631834763893091 0.000504819647616299 0.140779687268235 0.0297514168337676 0.000617892126006545 0.0011394500617625 0.820888386423681 1.0 1.0 0.38802190219888055
57 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.590361070334383 0.0 0.00283873189227405 0.901276452952094 0.0938738308613158 0.00141019974741145 0.000600784546904834 0.0 1.0 1.0 1.8695349995476385
58 O=C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)[C@H](C)N(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.63651378 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.442651256490317 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
59 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.97521151 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.530769863411841 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
60 O=C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)CN(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.88045619 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.48874872297084 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
61 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)CN(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.83327693 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.343844382133684 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
62 O=C(NCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.53889564 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.301494223781961 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
63 O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.27376909 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.596939379038152 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
64 O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.27376909 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 5.596939379038152 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
65 O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC DSPC 0 0 1 0 15.06368788 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.403665809777363 0.0159262664008309 0.00726471746994425 0.0644691443511897 0.0154248397225439 0.00666778094817397 0.00618426236554005 0.884062988741777 0.163983867672707 0.163983867672707 -0.8051696746745034
66 O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC DSPC 0 0 1 0 15.06368788 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.403665809777363 0.0 0.0110768066820314 0.679238145596264 0.289982439081482 0.0151104362851107 0.00459217235511197 0.0 0.0864824917721372 0.0864824917721372 -0.5681789657875123
67 O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC DSPC 0 0 1 0 15.91176651 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.285378059618076 0.00952025723585679 0.00424787112198889 0.0270494802958792 0.00951147065788185 0.00569809581675416 0.00864159943836194 0.935331225433277 0.22281247574214 0.22281247574214 -0.7212074197450102
68 O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC DSPC 0 0 1 0 15.91176651 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.285378059618076 0.0 0.00577401787332259 0.781123329740865 0.202386288853494 0.00852464019685452 0.00219172333546338 0.0 0.23688698835255 0.23688698835255 -0.16682580237138014
69 CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.11033537 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.0106352940962555 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
70 CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.11033537 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 5.0106352940962555 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
71 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.49121730591206 0.0307690543253117 0.000803846893528031 0.00327375890943859 0.00440309874760962 0.00131506681420977 0.00341198428561488 0.956023190024287 1.14370500641117 1.14370500641117 0.5931227328814345
72 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.49121730591206 0.0 0.0103006057269574 0.229208194092422 0.735779643429865 0.0182228400970524 0.00648871665370264 0.0 0.146101132843469 0.146101132843469 -0.40908711190961344
73 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.573885895948325 0.00305704097815131 0.00100491779320209 0.0165773259574103 0.0117710271412967 0.00208697129856503 0.00287252217431477 0.96263019465706 1.0 1.0 0.38802190219888055
74 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.573885895948325 0.0 0.00330040832612047 0.545398801975274 0.446192251044312 0.00323782528214899 0.00187071337214386 0.0 1.0 1.0 1.8695349995476385
75 O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.79756457 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.789042318607025 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
76 CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.40770989 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.168208681201016 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
77 CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.93089479 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.697749367281185 4.697749367281184 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
78 O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.38737682 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.2112383136936 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
79 CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.61200662 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.27999390910873 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
80 O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.2554924 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.611152257665639 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
81 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.391561 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.1422481808981475 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
82 O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC DSPC 0 0 1 0 16.63400342 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.515354881665727 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
83 O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC DSPC 0 0 1 0 17.25637024 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.57532934397707 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
84 O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC DSPC 0 0 1 0 17.79833258 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.451896454476337 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
85 O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.2554924 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.925077405734609 4.9250774057346085 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
86 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.391561 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.829912458665998 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
87 O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC DSPC 0 0 1 0 16.63400342 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.421728001525434 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
88 O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC DSPC 0 0 1 0 17.25637024 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.775756486563625 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
89 O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC DSPC 0 0 1 0 17.79833258 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 8.862341963516347 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
90 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.55042057 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 5.5506312951620265 5.550631295162026 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
91 OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O DSPC 0 0 1 0 14.34229222 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.47597224751641 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
92 CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O DSPC 0 0 1 0 15.30473405 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.563722996073918 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
93 CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O DSPC 0 0 1 0 16.11614863 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.275554390163365 4.275554390163364 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
94 CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O DSPC 0 0 1 0 16.80938411 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.35709336812867 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
95 O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.32727581 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.473579765600494 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
96 O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O DSPC 0 0 1 0 17.03239796 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.5612182984589085 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
97 O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.71577453 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.695924549256556 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
98 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O DSPC 0 0 1 0 14.72351388 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.857484114602081 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
99 CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O DSPC 0 0 1 0 15.6246954 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.483228515182849 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
100 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O DSPC 0 0 1 0 16.38850868 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.426521874560433 4.426521874560432 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
101 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O DSPC 0 0 1 0 17.04402965 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.412919498116252 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
102 O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.53558149 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.69866052907543 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
103 O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.95535314 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.9459189793765646 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
104 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.97521151 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.450269224770129 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
105 O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.46731585 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.659658371272161 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
106 O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.8769168 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.139321635057579 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
107 O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O DSPC 0 0 1 0 18.04309994 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.283448621312786 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
108 O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O DSPC 0 0 1 0 17.76093253 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.1455128487965 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
109 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 18.07661492 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.3551691805039985 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
110 O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 18.15212729 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 6.632923618509176 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
111 O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-] DSPC 0 0 1 0 12.69438691 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence TEA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.762173934797756 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
112 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.240751047315928 0.0111914004572023 0.00227125491616379 0.00877931935589419 0.0082437061808303 0.00401873844514775 0.00849693826019724 0.956998642384564 0.596141429580998 0.596141429580998 -0.18837922911736
113 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.240751047315928 0.0 0.00531733106486159 0.69156525750989 0.28508003495893 0.0160312488066627 0.00200612765965623 0.0 0.176602424488684 0.176602424488684 -0.3276946657499996
114 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.253340627045836 0.0210584248832937 0.000931640117614886 0.0300315170504259 0.0160360600660287 0.002060495753182 0.00519348457253804 0.924688377556917 0.507741968135695 0.507741968135695 -0.31454604422779553
115 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.253340627045836 0.0 0.00533934786984105 0.597844801683409 0.374278985337898 0.0199301473078145 0.00260671780103763 0.0 0.177860137006811 0.177860137006811 -0.3243384702286213
116 O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 18.15212729 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 8.664405571096625 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
117 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.498141613229568 0.00224222740615835 0.000962422246665562 0.00287219892799367 0.00322451176864607 0.00206661890626862 0.00333409585594076 0.985297924888327 0.792858557060483 0.792858557060483 0.0923823620278189
118 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.498141613229568 0.0 0.00657230701947091 0.556297397905001 0.404138164228711 0.0296624454205942 0.00332968542622302 0.0 0.20948041157182 0.20948041157182 -0.2399600273409918
119 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.462799844696365 4.462799844696364 0.0122002332749747 0.000591091003585345 0.00113975593374826 0.00176766182040017 0.00118628775621157 0.000814512180559894 0.98230045803052 1.58712844716331 1.58712844716331 1.2259922362734261
120 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.462799844696365 4.462799844696364 0.0 0.0055909076747788 0.864547542326111 0.121503978921508 0.00729914012568763 0.00105843095191469 0.0 0.762385942529413 0.762385942529413 1.2354638394013375
121 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.196600262926448 0.0390763854278316 0.00164994009844252 0.0661192424915616 0.0206209930549816 0.00197347693054232 0.00160454285244798 0.868955419144192 1.0 1.0 0.38802190219888055
122 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.196600262926448 0.0 0.00384316363496011 0.851255867494199 0.137210400166604 0.00701109092659647 0.000679477777641109 0.0 1.0 1.0 1.8695349995476385
123 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC DSPC 0 0 1 0 17.67788651 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.401951803481151 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
124 O=C(CCCCCCCCC)OCCCCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)CO)=O DSPC 0 0 1 0 17.86915095 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.421487703554795 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
125 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O DSPC 0 0 1 0 17.61285873 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.577593418217857 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
126 OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCCC(OCCCCCCCCC)=O DSPC 0 0 1 0 15.66191374 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DBU Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.647271362006727 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
127 OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.541058240520847 0.0155523974922323 0.00129152518305059 0.446962380102849 0.0407067099579296 0.00170625578284345 0.00421830607343662 0.489562425407659 1.0 4.04718291807415 4.73706835052163
128 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.379899373657707 0.0165979002447495 0.00361970146585138 0.310566371988181 0.0118953898978584 0.00727497963461814 0.00647222326114303 0.643573433507598 1.0 1.0 0.38802190219888055
129 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.83323084 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.1751562049585145 0.127270779777207 0.0355651632001246 0.0965373529640882 0.0454740204097531 0.0338026797538366 0.0465840928565864 0.614765911038405 0.0505010966098528 0.0505010966098528 -0.9671362699547936
130 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.95682792 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.416186486320586 0.0275897803818406 0.0140220813902507 0.0611423332934752 0.0248626002542061 0.0133347505104052 0.0187510241318683 0.840297430037954 0.11103838626238 0.11103838626238 -0.8807353246775064
131 C=CCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)=O DSPC 0 0 1 0 18.01719192 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.445588116163626 0.0250376334304389 0.00337885545037859 0.0517009582142691 0.0430146012578083 0.00350252056656834 0.00406753936383155 0.869297891716705 0.594087846809013 0.594087846809013 -0.19131017455153912
132 CCCCCCCCCCCC(OCCCCCCN(CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.28161356 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.381026134340298 0.00774884428490629 0.00205921183588078 0.0366644403250292 0.0113925424121347 0.00225130046176364 0.00414541402825956 0.935738246652026 0.903691788703443 0.903691788703443 0.2505674416217897
133 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.382151626862033 0.0281381236661192 0.00268792352252722 0.218417144486954 0.0369503427520482 0.00199553488006137 0.00289937744032574 0.708911553251965 1.0 1.0 0.38802190219888055
134 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.83044719 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.199605072879594 4.199605072879593 0.0747106900577881 0.0465999615731367 0.107994265529626 0.0501322770872438 0.0448116344718523 0.0485065251769853 0.627244646103368 0.0685266977729659 0.0685266977729659 -0.9414094990897005
135 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.94795095 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.333755086000182 0.0109650973341036 0.00500301836333305 0.0209516607489436 0.00928876974106986 0.00498354505150691 0.00613733877720584 0.942670569983837 0.624112412102086 0.624112412102086 -0.14845806079238213
136 CCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.64728116 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.333098961050458 4.3330989610504576 0.0312031939311219 0.00665572714585857 0.0303955096845431 0.016483404133503 0.00703656560389733 0.0108270584446455 0.897398541056431 0.396247798437663 0.396247798437663 -0.4736744378197291
137 O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 15.21401022 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 0.0 4.865224091322398 0.113993758795815 0.073640090558649 0.155999510493789 0.089181912745518 0.0778008933488344 0.0854800220277795 0.403903812029615 0.0331042054271613 0.0331042054271613 -0.991965723861604
138 O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.964966 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.177279038170981 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
139 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.327834405590455 0.0791681309989092 0.00438236238399703 0.207450725009039 0.0200057324176319 0.00435501692886232 0.00687586277442937 0.677762169487131 1.0 1.0 0.38802190219888055
140 O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.01143435 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.826712455935327 0.051854991416453 0.0528002488161413 0.131177333337399 0.0608349367134925 0.0676316423389937 0.091080124286102 0.544620723091419 0.0058976768275302 0.0058976768275302 -1.0307958367096368
141 O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.98131005 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.613138355637268 0.0349404656939791 0.032170759570341 0.107989787547248 0.0410644871922655 0.0376181677387698 0.0487295770112475 0.697486755246149 0.0093821747742871 0.0093821747742871 -1.025822638898096
142 O=C([C@H](CO)N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 13.72220648 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.45318382899021 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
143 O=C(CCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.27012616 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.256453162449338 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
144 O=C(CCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 15.19898065 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.86830338551846 4.868303385518459 0.0353281775739917 0.00307182736960491 0.034716407488313 0.0124183147896963 0.00493000176115631 0.00714349716206655 0.902391773855171 0.291015633780908 0.291015633780908 -0.6238654779555869
145 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.260282639765531 0.0263012913083446 0.00104221918552839 0.17396331575752 0.0231252484593015 0.00218421226891195 0.00250493797184971 0.770878775048544 1.0 1.0 0.38802190219888055
146 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.400848388914469 0.142104027989206 0.00287714799265922 0.215134204863943 0.0243152184566193 0.00619704480449007 0.00405451457231669 0.605317841320765 1.0 1.0 0.38802190219888055
147 CCCCCCCCCCCC(OCCCCCCN(CCN(C)CCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.06597416 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.3551691805039985 0.0696417285874694 0.0029599268608454 0.0569405498935433 0.0189535946790038 0.00628554949471398 0.00620455647115851 0.839014094013266 1.46543205325214 1.46543205325214 1.0523028700808776
148 O=C(OCCCCCCN([C@H](C(NCCN(C)CCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.80021894 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.318154558079471 4.3181545580794705 0.0260251149767627 0.00751090805185066 0.0532899531021804 0.0511794000344704 0.0152455710134586 0.0158624088727893 0.830886643948488 0.594741863231617 0.594741863231617 -0.19037673935045565
149 CCCCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)=O DSPC 0 0 1 0 17.89376817 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.605170185988092 4.605170185988091 0.00991904799330563 0.00800736011391533 0.0452217049389508 0.0197202047147262 0.0164331186633441 0.0158205463682553 0.884878017207502 0.0777961107519447 0.0777961107519447 -0.9281798674338029
150 O=C(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.61561565 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.886582645426277 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
151 CCCCCCCCCCCC(OCCCCCCN(CCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.01340623 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.190175207928333 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
152 O=C(OCCCCCCN([C@H](C(NCCOCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.7439276 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.2694176902912275 0.0273933363293668 0.0025481137083807 0.0489889660247262 0.00910395259986531 0.00553863037137659 0.00570731639004281 0.900719684576242 0.282511511559215 0.282511511559215 -0.6360028597730629
153 O=C(CCCCCCCCCCC)OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O DSPC 0 0 1 0 18.18802872 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.561949483533528 0.0107761878140537 0.0018907931479914 0.00906874325536026 0.00817364202148832 0.00369121050409089 0.00412231341943734 0.962277109837578 1.03869430459932 1.03869430459932 0.44324777229346224
154 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.8896653 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.422808628394115 0.0 0.00393259539867672 0.698404256940233 0.29082082024119 0.00482745799593445 0.00201486942396601 0.0 0.150267764477171 0.150267764477171 -0.3979684896277195
155 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.24735173134728 0.0 0.0193985055782088 0.642311593152982 0.297952931923085 0.0232690994142363 0.0170678699314884 0.0 0.0138284395356039 0.0138284395356039 -0.7620557072620823
156 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.776599301615622 0.0 0.00374237304524464 0.388696129733584 0.542462789676973 0.0600826887673663 0.00501601877683173 0.0 0.0757788640374704 0.0757788640374704 -0.5967415084575073
157 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.59784341060163 0.0 0.00454633850545055 0.547957057084188 0.42844914578143 0.0150324705651762 0.00401498806375593 0.0 0.0747683143174281 0.0747683143174281 -0.5994381520828621
158 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.37981918 0.465 46.5 0.075 7.5 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.784988612563928 4.784988612563927 0.0 0.00648649184357099 0.353238786148937 0.611732175774514 0.0204133713900616 0.00812917484291689 0.0 0.231046253558505 0.231046253558505 -0.18241175518238087
159 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.684905154006945 0.0 0.00209231248329155 0.858334702447977 0.133879376324869 0.0038743559198132 0.0018192528240494 0.0 1.0 1.0 1.8695349995476385
160 CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)C DSPC 0 0 1 0 18.00540724 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.583231278469338 4.583231278469337 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
161 CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)C DSPC 0 0 1 0 17.73535311 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.224056168743758 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
162 O=C(CCCCC(OCCCCCCN(CCCNC([C@@H](N(CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CO)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)=O)OCCCC(F)(F)F DSPC 0 0 1 0 18.72527826 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.972587226458726 4.972587226458725 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
163 O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC DSPC 0 0 1 0 17.8896653 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.363226005210164 0.0302618004269707 0.0170318389360463 0.0852511261606349 0.0321310738618372 0.020553836096385 0.0249767617646758 0.78979356275345 0.103578477209434 0.103578477209434 -0.8913823687978608
164 O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 17.93964861 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.27430221608671 0.0441668582339066 0.00173504332049564 0.0552287456296669 0.0103338721124601 0.00424436496446174 0.00798306414101548 0.876308051597994 0.118006736161235 0.118006736161235 -0.8707898510406828
165 O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.66483929 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.322011202263895 0.014374943627672 0.00199135248489222 0.0891563599260395 0.0109943655858212 0.00408170887074953 0.00721565797781185 0.872185611527014 0.120117219447052 0.120117219447052 -0.867777695195366
166 C=CCCCCCCCCC(OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.93091393 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.589955020181611 0.159505299591344 0.00863892692709962 0.059163494819016 0.0251436766117119 0.0207012928199433 0.0319161553971728 0.694931153833713 0.19624671777719 0.19624671777719 -0.7591230022455473
167 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.461068842013835 0.18227458966528 0.00260059752378256 0.10140002712747 0.0194272464327483 0.00394998811850684 0.00708234329707097 0.683265207835141 1.0 1.0 0.38802190219888055
168 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.897839799950911 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
169 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.87291972 0.3296703297 32.96703297 0.2197802198 21.97802198 0.4395604396 43.95604396 0.01098901099 1.098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.667205576907544 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
170 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.34369997 0.41322314050000003 41.32231405 0.16528925619999998 16.52892562 0.41322314050000003 41.32231405 0.00826446281 0.826446281 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.786658062033468 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
171 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.12329906 0.2702702703 27.02702703 0.32432432429999997 32.43243243 0.3783783784 37.83783784 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.520374534283375 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
172 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.602904588 0.25 25.0 0.4 40.0 0.3 30.0 0.05 5.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.2162671661789055 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
173 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.22342652 0.3846153846 38.46153846 0.2197802198 21.97802198 0.3846153846 38.46153846 0.01098901099 1.098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.634728988229636 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
174 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.21412129 0.4 40.0 0.3428571429 34.28571429 0.2285714286 22.85714286 0.028571428569999998 2.857142857 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.378896741664954 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
175 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.29890072 0.34653465349999996 34.65346535 0.396039604 39.6039604 0.2475247525 24.75247525 0.0099009901 0.99009901 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.661550519424199 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
176 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.62419529 0.4186046512 41.86046512 0.3720930233 37.20930233 0.1860465116 18.60465116 0.02325581395 2.325581395 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.552612935249416 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
177 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 5.021245473208271 0.0189024787568605 0.00542838949966448 0.0161874266221436 0.00564673685028802 0.0063903753402389 0.0111802988958026 0.936264294035002 0.0913658402077254 0.0913658402077254 -0.908812673116613
178 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.59373115 0.3783783784 37.83783784 0.3783783784 37.83783784 0.21621621619999998 21.62162162 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.484470400750307 0.220192249542946 0.000764987158036526 0.00117389921248248 0.000355328494502401 0.000727082388944626 0.00146163086877099 0.775324822334317 0.909323670538887 0.909323670538887 0.25860546111465654
179 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.02523135 0.35897435899999997 35.8974359 0.41025641030000004 41.02564103 0.20512820510000002 20.51282051 0.025641025640000002 2.564102564 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.474947598938117 0.0634606467339624 0.00208550415241484 0.000693953783467295 0.000703971489002912 0.00107462659382075 0.00306678394465369 0.928914513302678 0.68813569412733 0.68813569412733 -0.057081784806354334
180 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.01459482 0.5490196078 54.90196078 0.2352941176 23.52941176 0.1960784314 19.60784314 0.01960784314 1.960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.414493824811383 0.0115671522937999 0.000329262998462127 0.000782715410474643 0.000454168201139608 0.00050928396392566 0.0365052454816706 0.949852171650527 1.45919493888772 1.45919493888772 1.0434010414727322
181 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.50825332 0.5283018868 52.83018868 0.2641509434 26.41509434 0.1886792453 18.86792453 0.01886792453 1.886792453 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.573163389853005 0.0289504727873473 0.000587630380490671 0.00098172979734669 0.000247631664832521 0.000530890620697785 0.00148666967519347 0.967214975074092 1.18732779204068 1.18732779204068 0.6553827041429786
182 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.02959744 0.5090909091 50.90909091 0.2909090909 29.09090909 0.1818181818 18.18181818 0.01818181818 1.818181818 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.424367475163407 0.01918176556647 0.0010650954164724 0.0022206234626453 0.00126505200881015 0.0010329415925789 0.00258134917445057 0.972653172778573 0.519739549496667 0.519739549496667 -0.29742267487018065
183 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.0526464 0.43243243239999996 43.24324324 0.32432432429999997 32.43243243 0.21621621619999998 21.62162162 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.646312129319266 0.0173760673957131 0.000550323482827711 0.00231355504088989 0.000799250291024724 0.00171157517792979 0.00187915335599706 0.975370075255618 0.641975082983608 0.641975082983608 -0.12296382974571453
184 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.87880561 0.3902439024 39.02439024 0.3902439024 39.02439024 0.1951219512 19.51219512 0.0243902439 2.43902439 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.627909672957581 4.62790967295758 0.031425165165133 0.00121897501467252 0.00336392108926765 0.00273184674446895 0.00365496097119473 0.00253008289994281 0.95507504811532 0.292484943880311 0.292484943880311 -0.6217684269937327
185 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.72896002 0.41025641030000004 41.02564103 0.3076923077 30.76923077 0.2564102564 25.64102564 0.025641025640000002 2.564102564 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.6141299273595635 0.00243290161785256 0.00374029360494432 0.00771109158226845 0.00256075951190699 0.0024473081411263 0.00398520450059787 0.977122441041304 0.29000081469118 0.29000081469118 -0.6253138633910964
186 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.2936051730729785 0.0291199872991734 0.000702410023626044 0.0253755412996204 0.0176881988849176 0.000962484515645204 0.00126799370807735 0.92488338426894 1.0 1.0 0.38802190219888055
187 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.596835549198034 4.596835549198033 0.0642873127295256 0.000194616801396495 0.00548703707264694 0.0163820187916684 0.000849254927099769 0.000518055392084143 0.912281704285579 0.772854925639995 0.772854925639995 0.06383247693007311
188 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.26769266 0.3783783784 37.83783784 0.3783783784 37.83783784 0.21621621619999998 21.62162162 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.284827171296749 0.000820324065776298 6.77505055763446e-05 0.00130838737685328 0.00203458073148474 0.00044026025400656 0.00179231955954145 0.993536377506761 0.647354606156059 0.647354606156059 -0.11528598539707118
189 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 12.69845587 0.35897435899999997 35.8974359 0.41025641030000004 41.02564103 0.20512820510000002 20.51282051 0.025641025640000002 2.564102564 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.355939299910563 0.000606683031689403 0.000350488437662207 0.00200552330636915 0.00341592792036262 0.00135658595795651 0.00484812686613966 0.98741666447982 0.429472560198128 0.429472560198128 -0.42625489130230415
190 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.73864775 0.5490196078 54.90196078 0.2352941176 23.52941176 0.1960784314 19.60784314 0.01960784314 1.960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.210051369934071 0.0506054803736383 0.000934742670841204 0.00195746112246746 0.00131704918881155 0.00229254534633995 0.00362188526923176 0.93927083602867 0.295296757118666 0.295296757118666 -0.6177553084162161
191 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.22254695 0.5283018868 52.83018868 0.2641509434 26.41509434 0.1886792453 18.86792453 0.01886792453 1.886792453 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.19614876167715 0.000394517913167851 0.000925918583325644 0.00219111536287718 0.00192843383777798 0.00141208216065332 0.00279803133939282 0.990349900802805 0.423957111788814 0.423957111788814 -0.43412673292138043
192 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 16.73562869 0.5090909091 50.90909091 0.2909090909 29.09090909 0.1818181818 18.18181818 0.01818181818 1.818181818 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.324000197151533 0.0149763371723649 9.09516394922477e-05 0.00865819492777344 0.00337158611087041 0.000870833891384162 0.00234291805381448 0.9696891782043 0.799987755503576 0.799987755503576 0.10255740435442702
193 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.73441264 0.43243243239999996 43.24324324 0.32432432429999997 32.43243243 0.21621621619999998 21.62162162 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.638604962074329 0.00412763242238728 0.000587351434637121 0.00125519721482213 0.00156835329887146 0.00151910105091065 0.00332452673735467 0.987617837841017 0.519710678404319 0.519710678404319 -0.29746388070685387
194 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.55362203 0.3902439024 39.02439024 0.3902439024 39.02439024 0.1951219512 19.51219512 0.0243902439 2.43902439 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.465448242812954 0.001908149535057 0.00051106883667359 0.00195557181028906 0.00222543526142979 0.00102554934782431 0.0036709617373884 0.988703263471338 0.559906246507883 0.559906246507883 -0.24009535462913364
195 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.4082575 0.41025641030000004 41.02564103 0.3076923077 30.76923077 0.2564102564 25.64102564 0.025641025640000002 2.564102564 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.439351701293151 0.0164941051995163 0.00133624924425635 0.0136411729141475 0.0068725438331318 0.00281561744256348 0.00565863059250302 0.953181680773882 0.404416041627467 0.404416041627467 -0.4620164343493942
196 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.348211286179151 0.25310386523031 0.000588156076259717 0.140706646889545 0.17621759673582 0.00218337900345845 0.000839731767209391 0.426360624297398 1.0 1.0 0.38802190219888055
197 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.574298522321004 0.0173152888243317 0.00170643426094864 0.0181271736370668 0.0103847448319841 0.00234708518590686 0.00464250497463967 0.945476768285122 0.880302275630684 0.880302275630684 0.21718510735044552
198 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.54771521 0.3296703297 32.96703297 0.2197802198 21.97802198 0.4395604396 43.95604396 0.01098901099 1.098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.530015512387331 4.5300155123873305 0.0022188818222417 0.00151967168045253 0.0265741083102934 0.00935341146520975 0.00161955884356527 0.00594450434134348 0.952769863536894 0.693395601815244 0.693395601815244 -0.0495746598769834
199 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 16.03951812 0.41322314050000003 41.32231405 0.16528925619999998 16.52892562 0.41322314050000003 41.32231405 0.00826446281 0.826446281 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.640537329825382 0.0191565810814788 0.00120917820488213 0.00564887782228727 0.00368324602436162 0.00270413188019715 0.00625226385441887 0.961345721132374 0.702078866162311 0.702078866162311 -0.037181600128431615
200 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 10.8033785 0.2702702703 27.02702703 0.32432432429999997 32.43243243 0.3783783784 37.83783784 0.027027027029999998 2.702702703 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.2431955089544555 0.0191175904912105 0.0046774627841674 0.0253721583259607 0.0153479247605493 0.0105242912643767 0.0240873946993884 0.900873177674347 0.168910555827937 0.168910555827937 -0.7981381323616322
201 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 9.298704135 0.25 25.0 0.4 40.0 0.3 30.0 0.05 5.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.822697998516666 0.00783638212803346 0.00315432464612104 0.0156004284210389 0.0122536904537434 0.00649575798551451 0.014293561001533 0.940365855364016 0.26946434750834 0.26946434750834 -0.6546242303969191
202 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.90666525 0.3846153846 38.46153846 0.2197802198 21.97802198 0.3846153846 38.46153846 0.01098901099 1.098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.291292751611072 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
203 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.89035919 0.4 40.0 0.3428571429 34.28571429 0.2285714286 22.85714286 0.028571428569999998 2.857142857 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.388753955423308 0.0457836478243602 0.00256820195313693 0.0933595380902435 0.040121791020458 0.00303459231576053 0.00719748271402532 0.807934746082015 0.638042293066864 0.638042293066864 -0.12857684559650717
204 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 12.97231927 0.34653465349999996 34.65346535 0.396039604 39.6039604 0.2475247525 24.75247525 0.0099009901 0.99009901 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.500031867864786 0.00367784574047392 0.00111977791364668 0.0109807451773001 0.00533981749985873 0.0035253353907892 0.00945759694134628 0.965898881336585 0.664597706735618 0.664597706735618 -0.09067602683869287
205 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.30278396 0.4186046512 41.86046512 0.3720930233 37.20930233 0.1860465116 18.60465116 0.02325581395 2.325581395 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.578518154990665 0.00602415700375336 0.00352191807012307 0.0129438874596237 0.0112365957475355 0.00705054455561779 0.0163551166761144 0.942867780487232 0.387412476367661 0.387412476367661 -0.486284519689253
206 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DOPE 1 0 0 0 14.78083639 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.373742415086184 0.00132025329631253 0.000860633620224201 0.00503931327076771 0.0029913613071963 0.00270028184029275 0.0088532339643477 0.978234922700859 1.0 1.0 0.38802190219888055
207 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.434619084793052 0.00770185399584477 0.00244833711322221 0.0462111239750686 0.0198642411939162 0.00381226904350308 0.00922041774380283 0.910741756934642 1.0 1.0 0.38802190219888055
208 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 11.7812451 0.5490196078 54.90196078 0.2352941176 23.52941176 0.1960784314 19.60784314 0.01960784314 1.960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.485936098064394 4.485936098064393 0.00448668985970796 0.00155299888410839 0.00808200908228358 0.00771278024096098 0.00385266053622471 0.00536687174407294 0.968945989652641 1.22295554827804 1.22295554827804 0.7062318887477964
209 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.01459482 0.5490196078 54.90196078 0.2352941176 23.52941176 0.1960784314 19.60784314 0.01960784314 1.960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.73444252169223 0.00221922165343577 0.00134658478491355 0.00928071520245763 0.0103471897935628 0.00308928870366618 0.00305991935175966 0.970657080510204 2.4848301850992 2.4848301850992 2.507223675274371
210 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.379899373657707 0.0165979002447495 0.00361970146585138 0.310566371988181 0.0118953898978584 0.00727497963461814 0.00647222326114303 0.643573433507598 1.0 1.0 0.38802190219888055
211 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 0.5 50.0 0.1 10.0 0.385 38.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.7140245909001735 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
212 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.85564 0.309 30.9 0.363 36.3 0.259 25.9 0.069 6.9 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.002960000420248 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
213 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 12.10629825 0.337 33.7 0.322 32.2 0.28800000000000003 28.8 0.054000000000000006 5.4 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 3.9917579734469997 3.9917579734469992 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
214 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.076607527 0.215 21.5 0.44299999999999995 44.3 0.27399999999999997 27.4 0.067 6.7 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.150252194160397 4.150252194160396 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
215 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.262126773 0.285 28.5 0.369 36.9 0.233 23.3 0.114 11.4 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 3.9384701754429945 3.938470175442994 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
216 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.14390228 0.47 47.0 0.40399999999999997 40.4 0.057 5.7 0.068 6.8 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.139158578011894 4.139158578011893 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
217 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.465333240800292 0.0929588198875335 0.00109661539851913 0.0103406974639253 0.00262333547972377 0.00257373980843396 0.00319533888859958 0.887211453073265 2.49616154919077 2.49616154919077 2.5233961959539766
218 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.95064466 0.41 41.0 0.395 39.5 0.16 16.0 0.035 3.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.25063580654847 0.00217929592656579 0.00233573351378476 0.00718449647353577 0.00718369422949875 0.00471157922942054 0.00408542775852615 0.972319772868668 1.71461830076508 1.71461830076508 1.4079502315467747
219 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.40653622 0.31333300000000003 31.3333 0.31333300000000003 31.3333 0.31333300000000003 31.3333 0.06 6.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.188896879163323 0.0142737392382439 0.00348189340868737 0.00880858320276677 0.0038525568856599 0.00593274588142816 0.00610316587084082 0.957547315512373 0.645718762121967 0.645718762121967 -0.11762071943757772
220 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.77836699 0.5 50.0 0.235 23.5 0.235 23.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.343935283551159 0.0065593281978378 0.00138907609400551 0.00613919753007927 0.00613411120238244 0.00366825953495706 0.00406194129869205 0.972048086142046 1.35219591573978 1.35219591573978 0.890688278863242
221 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.200348974 0.22 22.0 0.22 22.0 0.5 50.0 0.06 6.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.057161771094385 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
222 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.72417162 0.27 27.0 0.27 27.0 0.41 41.0 0.05 5.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.102973888920155 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
223 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.092439729 0.16 16.0 0.395 39.5 0.41 41.0 0.035 3.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.127940511650616 0.0097349353786325 0.00823434520879355 0.0380775286515883 0.0189007253206434 0.0281939358827934 0.0273826912679074 0.869475838289641 0.161929321885153 0.161929321885153 -0.8081019945583146
224 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.93804335 0.395 39.5 0.16 16.0 0.41 41.0 0.035 3.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.116269119637892 0.00176070173692806 0.00134882241229812 0.00721447825021801 0.00277771416530431 0.00258248336542972 0.00338400053115958 0.980931799538662 0.834918279031508 0.834918279031508 0.15241147395626697
225 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.312676556539088 0.0122849683487715 0.00187692747865846 0.313004652084084 0.0267625511357853 0.00478000951875277 0.00400214034383056 0.637288751090117 1.0 1.0 0.38802190219888055
226 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.5612182984589085 0.00230427148121394 0.00151653786120671 0.00981883965091339 0.0195498469521307 0.00278714514326426 0.00256552165624032 0.961457837255031 3.54213716664653 3.54213716664653 4.0162493217529285
227 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.95064466 0.41 41.0 0.395 39.5 0.16 16.0 0.035 3.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.2756934238792645 0.00339636246099529 0.00439836397767252 0.00922438120812044 0.0070906355917358 0.00777777401057153 0.0070228258793507 0.961089656871554 1.60048193764837 1.60048193764837 1.2450508067393784
228 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.77836699 0.5 50.0 0.235 23.5 0.235 23.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.300138475201197 0.0251900613139205 0.0263858529561065 0.0690244086529141 0.0290319859464883 0.0512059292322219 0.0395084822769767 0.759653279621372 0.244442812501583 0.244442812501583 -0.6903358436733202
229 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.93804335 0.395 39.5 0.16 16.0 0.41 41.0 0.035 3.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.035478809355064 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
230 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.07835597 0.41 41.0 0.4 40.0 0.16 16.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.314416735011824 0.00832740543716945 0.00279899792781369 0.0133506530995165 0.00590470004845411 0.00800781451355169 0.00611088774111073 0.955499541232384 1.4036171732161 1.4036171732161 0.9640785029516001
231 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 12.46964291 0.32299999999999995 32.3 0.32299999999999995 32.3 0.32299999999999995 32.3 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.122932019074013 0.00935369123549862 0.00681432683334856 0.0266295187790274 0.0091342786879667 0.0148394527045059 0.0109795829907811 0.922249148768872 0.807897092094877 0.807897092094877 0.11384588723707807
232 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.214347354616797 0.00175971204953205 0.0023945553766021 0.00864096914216858 0.00287247113967731 0.00354165273920712 0.00438932700137801 0.976401312551435 2.1807873939408 2.1807873939408 2.073283128685432
233 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.297557478047431 0.0163588203416613 0.0050349858804786 0.141665503002976 0.0268932928836599 0.0108166459136593 0.00842178986187252 0.790808962115693 1.0 1.0 0.38802190219888055
234 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.623991940228679 0.0114998638575461 0.00130788860611426 0.00505223783079306 0.0046933168158669 0.00183202266239377 0.00287251942980201 0.972742150797484 1.19732008331576 1.19732008331576 0.6696440530835793
235 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.47398367 0.415 41.5 0.405 40.5 0.16 16.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.261975403606051 0.0120973279883405 0.00779128029381303 0.0260350268299895 0.0160802201335602 0.0156019499205845 0.0170739234476819 0.90532027138603 0.213285375768679 0.213285375768679 -0.7348048313269125
236 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.72570651 0.405 40.5 0.16 16.0 0.415 41.5 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.168678699274804 0.00644850088058007 0.00798921970887525 0.0221223520376599 0.0111631004951633 0.0106463671035197 0.00996963598739929 0.931660823786802 0.29077874869216 0.29077874869216 -0.6242035686713655
237 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.63764671 0.415 41.5 0.405 40.5 0.165 16.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.40562108352751 0.0088141667427258 0.00585903666298478 0.0157870816204507 0.010986042994209 0.00978368783097364 0.0102623946891479 0.938507589459508 0.370029347989408 0.370029347989408 -0.5110943308383519
238 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.402441819416474 0.154933534385178 0.00229861102597737 0.00525615721273492 0.00408539799683711 0.0022876287732977 0.00287249757879639 0.828266173027179 1.34933481107146 1.34933481107146 0.88660480982624
239 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.91076362 0.42 42.0 0.405 40.5 0.165 16.5 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.607168188650764 0.0408588610755303 0.0177373482989948 0.0425327283385076 0.0277718677406049 0.0276871974121274 0.0218927074965806 0.821519289637654 0.158736230637426 0.158736230637426 -0.8126592864976097
240 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.86872188 0.49 49.0 0.25 25.0 0.24 24.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.4277167605909975 4.427716760590997 0.00307921600642319 0.00224989559352084 0.00599370029233814 0.00443157985269048 0.00263031532778781 0.00293093049696406 0.978684362430275 1.27822314397057 1.27822314397057 0.785111741784596
241 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.444179499895966 0.0412236553892641 0.00390663231476925 0.121517080143859 0.0188177267921366 0.00482332620655526 0.0073631886059774 0.802348390547439 1.0 1.0 0.38802190219888055
242 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.573473099244837 4.573473099244836 0.00689869445402741 0.00600089779665737 0.0191135089301672 0.00620664286397134 0.00981653359048003 0.0097967903769499 0.942166931987747 0.749333285576466 0.749333285576466 0.030261566378477555
243 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.88644869 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.688591794127164 0.00886147101476089 0.00436553876298869 0.0150948084008648 0.00476112441477112 0.00826588994437132 0.00836456609804533 0.950286601364198 0.883781845590108 0.883781845590108 0.22215127176544153
244 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.877221176 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.829113417472866 0.00517423746484337 0.00420818785762778 0.0136338012801862 0.00389526355348657 0.0081026937251479 0.00825574629036951 0.956730069828339 1.02766134878372 1.02766134878372 0.4275011503825392
245 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.07835597 0.41 41.0 0.4 40.0 0.16 16.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4595662121293 0.025369932029363 0.00629969301959379 0.0185849502075566 0.00668329267445478 0.00984673129800659 0.00995848867776924 0.923256912093256 0.773367707896157 0.773367707896157 0.06456433777003012
246 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.306031912 0.41 41.0 0.4 40.0 0.16 16.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.528073135603124 0.00974026247143072 0.00459547921939943 0.0155882894773368 0.00424301614179951 0.00735125258984654 0.00918675243548622 0.949294947664701 0.925634770529548 0.925634770529548 0.28188523570969626
247 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 6.950074466 0.41 41.0 0.4 40.0 0.16 16.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.730921391293652 4.730921391293651 0.0307398296858454 0.00502448817507942 0.0144391987292623 0.00475975114719379 0.00732990645958348 0.00864531856689022 0.929061507236145 0.282355212986546 0.282355212986546 -0.6362259345836732
248 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.3578620076745835 0.0575651939642587 0.00224327504140443 0.293214190330324 0.103801109257072 0.00316596887134689 0.00243404296405076 0.537576219571543 1.0 1.0 0.38802190219888055
249 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.1515122352784415 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
250 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.0693509 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.2656332579940335 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
251 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.52014814 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.431173877940127 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
252 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.436396441739405 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
253 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.50369223 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.5666372362713075 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
254 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.844529643 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.765586907393996 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
255 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.149936935645806 0.0412282002133458 0.00282906106065428 0.0100452919302821 0.00294646346634102 0.0035555046437446 0.00510039590268196 0.93429508278295 2.31132936702855 2.31132936702855 2.259597216050143
256 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.0693509 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.244200317766478 0.0307672106546614 0.0492440442693678 0.143087600825361 0.0409904333145751 0.0410729694241231 0.0628737572688051 0.631963984243106 0.159668526820479 0.159668526820479 -0.8113286806519148
257 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.52014814 0.4 40.0 0.16 16.0 0.41 41.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.430459592195472 4.430459592195471 0.0144382835185698 0.030629687100469 0.0904231657039977 0.0327120644783899 0.0374915496460484 0.0408664371206098 0.753438812431916 0.342029093157046 0.342029093157046 -0.551057277633741
258 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.560277417097355 0.064087583051715 0.00731756531038673 0.0186036957891068 0.0053871458118381 0.00655845861152129 0.0086069303650773 0.889438621060355 2.14638048731397 2.14638048731397 2.024176383509215
259 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.50369223 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.667205576907544 0.00310349569550498 0.00416831577034203 0.0115025538737423 0.00349250282837259 0.00500126547712412 0.00690260249517487 0.965829263859739 3.35844880423818 3.35844880423818 3.754082841561727
260 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.844529643 0.405 40.5 0.165 16.5 0.415 41.5 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.713127327493184 0.00089376253365906 0.00183788568066981 0.0054363636464257 0.00195410248071216 0.00225811087193407 0.00383533887250888 0.98378443591409 3.24722414573894 3.24722414573894 3.595339103815341
261 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.359653205696989 0.0828383439279835 0.00565653685524585 0.157248489872984 0.00928479521934879 0.00688752099561758 0.00841921269728692 0.729665100431533 1.0 1.0 0.38802190219888055
262 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.86872188 0.49 49.0 0.25 25.0 0.24 24.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.634728988229636 0.00818072805535472 0.00273349879854757 0.0119346096951512 0.0075308964437597 0.00591367796700706 0.00578329104170321 0.957923297998477 0.213428398303373 0.213428398303373 -0.7346007045438266
263 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.15051107 0.49 49.0 0.25 25.0 0.24 24.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.7140245909001735 0.0160361616147136 0.00185083446366488 0.00730973501824061 0.00349956550575257 0.00416153151105757 0.00426975100661699 0.962872420879954 0.319359456002154 0.319359456002154 -0.5834121797200126
264 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.327596879 0.49 49.0 0.25 25.0 0.24 24.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.822697998516666 0.0208671125611406 0.0200298903914976 0.0765668274895919 0.0297655881927753 0.0442427715485906 0.0417155046265625 0.766812305189841 0.0431568482237034 0.0431568482237034 -0.9776182391106099
265 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.548282323781043 0.235642631118293 0.00357683071882224 0.268183756367962 0.0537803810677977 0.0056567696761597 0.00550191880428196 0.427657712246684 1.0 1.0 0.38802190219888055
266 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.41834022 0.5 50.0 0.075 7.5 0.415 41.5 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.892602227184663 0.0004 0.0007 0.8627 0.1335 0.0019 0.0008 0.0 0.33 0.33 0.08164550420240263
267 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.34376213 0.5 50.0 0.29 29.0 0.2 20.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.935911747900319 0.0015 0.0017 0.585 0.3856 0.0215 0.0046 0.0 0.09 0.09 -0.5587925239809655
268 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.47881241 0.455 45.5 0.075 7.5 0.45 45.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.657762636107262 0.0008 0.0009 0.9399 0.0565 0.0012 0.0006 0.0 0.26 0.26 -0.10514892068441307
269 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.58994389 0.5 50.0 0.1775 17.75 0.3025 30.25 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.6520537718869415 0.0009 0.0008 0.8853 0.11 0.0021 0.0009 0.0 0.31 0.31 0.028275668520455245
270 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.356515817 0.38 38.0 0.3 30.0 0.3 30.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.522874943261261 0.0008 0.0012 0.7508 0.2416 0.0048 0.0008 0.0 0.12 0.12 -0.4787377704580445
271 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.211083767 0.38 38.0 0.16 16.0 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.802380355275797 0.0003 0.0007 0.8979 0.0985 0.0022 0.0005 0.0 0.45 0.45 0.40186451829408665
272 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.891852481 0.38 38.0 0.23 23.0 0.38 38.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.721173861744398 4.721173861744397 0.0003 0.0009 0.9061 0.0898 0.0024 0.0005 0.0 0.3 0.3 0.0015907506794815506
273 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.59856338 0.4596 45.96 0.2483 24.83 0.2671 26.71 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.599152113662528 0.0006 0.0011 0.8386 0.1563 0.0028 0.0007 0.0 0.36 0.36 0.16170025772532357
274 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.516252746 0.4458 44.58 0.19329999999999997 19.33 0.3308 33.08 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.539030383483547 4.539030383483546 0.0011 0.0009 0.9163 0.0784 0.0025 0.0008 0.0 0.24 0.24 -0.15851875636636045
275 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.79855736 0.5 50.0 0.075 7.5 0.395 39.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.602165676967792 0.0007 0.0007 0.9622 0.0349 0.001 0.0005 0.0 0.91 0.91 1.6293707389788754
276 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.789158454 0.425 42.5 0.3 30.0 0.245 24.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.506454213048934 0.0013 0.0022 0.7003 0.2848 0.009 0.0025 0.0 0.1 0.1 -0.5321076061399918
277 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.924427289 0.4471 44.71 0.1358 13.58 0.3921 39.21 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.543294782270004 0.0006 0.0008 0.9464 0.0496 0.0015 0.0011 0.0 0.56 0.56 0.6953986145447971
278 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.213203287 0.4146 41.46 0.2483 24.83 0.3221 32.21 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.600157644164547 0.0006 0.0011 0.9277 0.0684 0.0014 0.0008 0.0 0.44 0.44 0.37517960045311294
279 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.766920469 0.38 38.0 0.14 14.0 0.45 45.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.380775852772229 0.0005 0.001 0.9807 0.0157 0.0015 0.0006 0.0 0.46 0.46 0.42854943613506036
280 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.9150442 0.5 50.0 0.27 27.0 0.2 20.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.490881039585964 0.0013 0.001 0.7257 0.2649 0.0061 0.0009 0.0 0.13 0.13 -0.4520528526170708
281 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.33144164 0.47240000000000004 47.24 0.1119 11.19 0.3887 38.87 0.0271 2.71 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.627909672957581 4.62790967295758 0.0073 0.0639 0.7768 0.1461 0.0042 0.0016 0.0 1.3 1.3 2.670082534776849
282 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.92222847 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.8543712716215905 0.001 0.001 0.8647 0.1302 0.0025 0.0007 0.0 0.25 0.25 -0.13183383852538677
283 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.314817884980432 0.0009 0.0007 0.9116 0.0844 0.0018 0.0006 0.0 1.0 1.0 1.8695349995476385
284 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.42041204 0.49 49.0 0.075 7.5 0.415 41.5 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.534747721691546 4.534747721691545 0.0013 0.0021 0.5194 0.4632 0.0111 0.0029 0.0 0.5 0.5 0.535289107498955
285 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 15.70987342 0.3425 34.25 0.1875 18.75 0.45 45.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.191168746857641 4.19116874685764 0.0011 0.0011 0.7685 0.2222 0.0053 0.0018 0.0 0.15 0.15 -0.3986830169351235
286 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 11.2192693 0.22 22.0 0.3 30.0 0.45 45.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.151039905898646 0.0028 0.0014 0.4022 0.5806 0.0101 0.003 0.0 0.05 0.05 -0.6655321953448602
287 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.76101632 0.49 49.0 0.28 28.0 0.2 20.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.154184562578117 0.001 0.0012 0.5862 0.3912 0.0188 0.0017 0.0 0.16 0.16 -0.37199809909414977
288 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.31421044 0.4461 44.61 0.2489 24.89 0.27940000000000004 27.94 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.155753190350744 0.0041 0.0015 0.5886 0.3825 0.0211 0.0022 0.0 0.13 0.13 -0.4520528526170708
289 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 14.60470229 0.3211 32.11 0.2489 24.89 0.4044 40.44 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.104294893075269 4.104294893075268 0.0017 0.0016 0.5892 0.3913 0.0129 0.0033 0.0 0.05 0.05 -0.6655321953448602
290 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.00750041 0.49 49.0 0.1875 18.75 0.3125 31.25 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.516338972281476 0.0111 0.0048 0.1796 0.7293 0.0671 0.0082 0.0 0.14 0.14 -0.4253679347760971
291 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.77390107 0.4213 42.13 0.1875 18.75 0.38130000000000003 38.13 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.33204826486764 0.0167 0.0049 0.2598 0.6793 0.0289 0.0104 0.0 0.15 0.15 -0.3986830169351235
292 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.21646499 0.4561 45.61 0.1364 13.64 0.38189999999999996 38.19 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.365643155423357 0.0042 0.0015 0.3443 0.6172 0.0298 0.003 0.0 0.2 0.2 -0.2652584277302551
293 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.27353562 0.445 44.5 0.075 7.5 0.45 45.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.436751534363128 0.0067 0.0013 0.5909 0.385 0.0142 0.0019 0.0 0.22 0.22 -0.21188859204830776
294 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.27759176 0.49 49.0 0.3 30.0 0.2 20.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.151039905898646 0.0122 0.0028 0.2395 0.6818 0.0594 0.0044 0.0 0.08 0.08 -0.5854774418219391
295 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 14.75114553 0.345 34.5 0.3 30.0 0.325 32.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.248495242049359 4.2484952420493585 0.0029 0.0024 0.3338 0.6429 0.0151 0.0029 0.0 0.07 0.07 -0.6121623596629128
296 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 16.61008 0.3936 39.36 0.2489 24.89 0.3419 34.19 0.015600000000000001 1.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.384523514872469 0.0141 0.0106 0.3243 0.5845 0.0592 0.0073 0.0 0.14 0.14 -0.4253679347760971
297 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 12.46688772 0.24 24.0 0.3 30.0 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.796616650559047 4.796616650559046 0.0064 0.0026 0.3777 0.6006 0.0093 0.0034 0.0 0.1 0.1 -0.5321076061399918
298 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.37981918 0.465 46.5 0.075 7.5 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.516338972281476 0.0024 0.0028 0.4642 0.5174 0.0093 0.0039 0.0 0.81 0.81 1.362521560569139
299 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 16.04448224 0.3736 37.36 0.2994 29.94 0.3171 31.71 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.370712874773608 0.033 0.008 0.1094 0.8115 0.0325 0.0056 0.0 0.11 0.11 -0.5054226882990182
300 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.623010104116422 0.0087 0.0033 0.2348 0.7393 0.011 0.003 0.0 0.36 0.36 0.16170025772532357
301 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.375757021660286 0.0019 0.0023 0.9077 0.0818 0.0033 0.003 0.0 1.0 1.0 1.8695349995476385
302 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.34776106 0.49 49.0 0.075 7.5 0.415 41.5 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.943782987108415 0.0542 0.0001 0.3146 0.0378 0.0014 0.0006 0.5913 1.14 1.14 0.5878348176473546
303 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.630330503 0.3425 34.25 0.1875 18.75 0.45 45.0 0.02 2.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.395682961121367 0.03 0.0006 0.0837 0.0261 0.002 0.0013 0.8563 0.78 0.78 0.07403017792270697
304 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 5.746375559 0.22 22.0 0.3 30.0 0.45 45.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.264087336809195 0.0156 0.0014 0.0138 0.0104 0.0025 0.0031 0.9532 0.32 0.32 -0.5824979728365652
305 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.15734025 0.49 49.0 0.28 28.0 0.2 20.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.513054897080286 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
306 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.812051718 0.4461 44.61 0.2489 24.89 0.27940000000000004 27.94 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.470495282661489 0.009 0.0004 0.0178 0.0948 0.0017 0.0003 0.8762 1.05 1.05 0.45938365771619283
307 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 7.893697629 0.3211 32.11 0.2489 24.89 0.4044 40.44 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.289088639014612 0.0343 0.0003 0.1697 0.027 0.0013 0.0009 0.7666 0.46 0.46 -0.38268505738809105
308 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.08675917 0.49 49.0 0.1875 18.75 0.3125 31.25 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.9684234452869465 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
309 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.13512977 0.4213 42.13 0.1875 18.75 0.38130000000000003 38.13 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.906015244966153 0.0128 0.0 0.028 0.0208 0.0006 0.0 0.9378 0.93 0.93 0.28811544447464355
310 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.43848511 0.4561 45.61 0.1364 13.64 0.38189999999999996 38.19 0.0256 2.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.525044141508807 4.525044141508806 0.0635 0.0002 0.2019 0.083 0.0009 0.0003 0.6502 1.5 1.5 1.1016394573720025
311 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.44748395 0.445 44.5 0.075 7.5 0.45 45.0 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4520190064939165 0.011 0.0005 0.3972 0.0536 0.0016 0.0009 0.5352 1.45 1.45 1.0302777018546903
312 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.57169095 0.49 49.0 0.3 30.0 0.2 20.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.86830338551846 4.868303385518459 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
313 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.009941019 0.345 34.5 0.3 30.0 0.325 32.5 0.03 3.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.3476939555933765 0.0165 0.0 0.0427 0.0616 0.0035 0.0028 0.8728 0.42 0.42 -0.43977446180194085
314 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.301142352 0.3936 39.36 0.2489 24.89 0.3419 34.19 0.015600000000000001 1.56 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.629862798578463 0.0246 0.0 0.1245 0.0895 0.0015 0.0023 0.7576 0.44 0.44 -0.41122975959501595
315 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 6.525773643 0.24 24.0 0.3 30.0 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.732683506287051 0.006 0.0012 0.0205 0.0177 0.0008 0.0 0.9538 0.44 0.44 -0.41122975959501595
316 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.31765932 0.465 46.5 0.075 7.5 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.81380905109942 4.813809051099419 0.073 0.0 0.0373 0.0149 0.0 0.0 0.8748 1.01 1.01 0.40229425330234303
317 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.01888288 0.4637 46.37 0.075 7.5 0.4421 44.21 0.0192 1.92 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.706823839714591 0.0145 0.0004 0.1165 0.019 0.0007 0.0011 0.8477 1.94 1.94 1.7296229059243498
318 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.30562834 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.73795129722191 0.0343 0.0003 0.1697 0.027 0.0013 0.0009 0.7666 1.9 1.9 1.6725335015104998
319 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 9.480986593 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.302712827954156 0.0455 0.0 0.324 0.073 0.0011 0.0012 0.5551 1.0 1.0 0.38802190219888055
320 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 17.88551615 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.763028270603671 0.0253701689981931 0.00985209592098701 0.307949537646453 0.622300893638244 0.0174680522283724 0.0170592515677505 0.0 0.0
321 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 17.94390528 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.584559232083967 0.00894763570081526 0.00182903773179144 0.430416319953847 0.549730482792046 0.00757886856613304 0.0014976552553668 0.0 0.0019532059842532 0.0019532059842532 -0.793744670428099
322 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 18.3291697 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.5827200571505 0.00757568328250189 0.00220510873539676 0.728025615125869 0.236446776884745 0.0226429923353559 0.00310382363613184 0.0 0.0011482099710543 0.0011482099710543 -0.7958927956755514
323 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 18.38109198 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.6888677450096585 4.688867745009658 0.00599960547383456 0.00187471922407934 0.58725363712808 0.393842224090862 0.00908706069367491 0.00194275338946932 0.0 0.0005585876781053 0.0005585876781053 -0.7974661979200065
324 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 19.03103458 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.374372415737022 0.0207124354254999 0.00767807173489595 0.560331852523788 0.3797189836544 0.0206003960524344 0.0109582606089812 0.0 0.0001489580680618 0.0001489580680618 -0.7985592911689305
325 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 19.07349618 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.567572155572773 0.0084525958204246 0.00170600389954699 0.807774257087237 0.172171860632781 0.00851123850670424 0.00138404405330582 0.0 0.0052460712339961 0.0052460712339961 -0.7849576865630203
326 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 17.88551615 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.763028270603671 0.0142965461163966 0.00273099369058116 0.2951874813445 0.196790510597468 0.00567584660232592 0.00900724719724339 0.476311374451485 0.0033203605888808 0.0033203605888808 -1.0344742729359027
327 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 17.94390528 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.584559232083967 0.0426258503334726 0.000887127042175757 0.102099604743599 0.057196348771858 0.00222434780081794 0.00162961025671667 0.79333711105136 0.0465195426566469 0.0465195426566469 -0.972818883550547
328 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 18.3291697 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.5827200571505 0.0182648912592805 0.000462867676668248 0.083073077462289 0.0429608616930204 0.00195825764287227 0.000923423624969053 0.852356620640901 0.0509209522037464 0.0509209522037464 -0.9665370373099135
329 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 18.38109198 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.6888677450096585 4.688867745009658 0.0068908069603713 0.000629547873998548 0.021394314943629 0.042448777163022 0.00198708372142952 0.00248444060475972 0.92416502873279 0.016201262972428 0.016201262972428 -1.0160901968011615
330 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 19.03103458 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.374372415737022 0.0116932676375475 0.00103739027764326 0.0525071135910941 0.0215477599193875 0.00368874758435242 0.00400972460855577 0.905515996381419 0.006104461793755 0.006104461793755 -1.0305007059455489
331 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 19.07349618 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.567572155572773 0.0237911981258413 0.00067207203055979 0.18334881014348 0.0466442684044473 0.00188246389345958 0.000953648344707904 0.742707539057504 0.0550488822731985 0.0550488822731985 -0.9606455105817374
332 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.82491214 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GLN Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.572543683160998 0.000714997259249526 0.000661552142657172 0.125943320778554 0.801966162874089 0.0693146503097598 0.00139931663568972 0.0 0.0127373438778132 0.0127373438778132 -0.764967287060561
333 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.91081918 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence BIM Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.358502089626924 0.00147233862420237 0.00107405472963131 0.901430168335102 0.0923159134092667 0.00310160866776492 0.000605916234032228 0.0 0.0763434621140544 0.0763434621140544 -0.5952348831288257
334 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81357262 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence 3FLA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.396299293960601 4.3962992939606 0.00110223184180453 0.00161797426133587 0.963322201717795 0.0321995776177804 0.00129202117564397 0.000465993385639812 0.0 0.380376087923258 0.380376087923258 0.21607368094058316
335 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.351438552905858 0.00061802522712851 0.00208191419961706 0.00520107649990865 0.018780252186508 0.966671145724669 0.00664758616216931 0.0 0.0289886812604962 0.0289886812604962 -0.7216007267742771
336 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2 DSPC 0 0 1 0 16.99522451 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence IZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.544995462952021 0.00423798522906651 0.00360605985882706 0.0132163308359338 0.182768863634774 0.789078621894797 0.00709213854660109 0.0 0.0033387326299993 0.0033387326299993 -0.7900474039572776
337 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.80884374 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PY Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.237000862623624 0.0123483310685072 0.00430719249252366 0.0429874465070588 0.751978605237179 0.174073814828135 0.0143046098665965 0.0 0.0005090956767902 0.0005090956767902 -0.7975982669188943
338 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.790487251761845 4.790487251761844 0.00153513483125764 0.00147931904743739 0.82338319944907 0.169033483447006 0.00378262362292623 0.000786239602302501 0.0 0.306009500746919 0.306009500746919 0.017627054049161966
339 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 17.10338647 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.842058839093973 0.00164287085070931 0.000659195379539964 0.94017588697419 0.0550751037989028 0.00183173459161262 0.000615208405045708 0.0 0.504231824712829 0.504231824712829 0.5465816969768794
340 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.82491214 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence GLN Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.572543683160998 0.0204881792124896 0.00996076677576078 0.024515683125648 0.0206076067733214 0.0213656753332114 0.0146396167476402 0.888422472031929 0.0035574041476412 0.0035574041476412 -1.0341359560461585
341 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.91081918 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence BIM Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.358502089626924 0.0789442718629389 0.000859220559164078 0.352513414289749 0.0167725689541561 0.00207992092629201 0.000939235620822743 0.547891367786878 0.128034152082589 0.128034152082589 -0.8564783709716817
342 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81357262 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence 3FLA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.396299293960601 4.3962992939606 0.020589791219893 0.00221295822133462 0.77006639472807 0.0336156368936998 0.00141982059640497 0.000804331444027444 0.17129106689657 0.352623838360951 0.352623838360951 -0.5359360852935553
343 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 1.0 4.351438552905858 0.0518701933925729 0.031230151711712 0.196119602463562 0.0891250765615729 0.225998436967717 0.183312147304902 0.222344391597961 0.0006916766953858 0.0006916766953858 -1.0382260228827003
344 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2 DSPC 0 0 1 0 16.99522451 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence IZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.544995462952021 0.0318134391856252 0.0195739470918212 0.0658637908929555 0.0405146823853727 0.0383355214778253 0.0445803960220688 0.759318222944331 0.0007826107131428 0.0007826107131428 -1.0380962386598327
345 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.80884374 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PY Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.237000862623624 0.0496007240706346 0.0248050760368446 0.125156740550784 0.0913290655906173 0.0605654916232193 0.0647609529825488 0.583781949145352 0.000319594239126 0.000319594239126 -1.0387570720282182
346 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.790487251761845 4.790487251761844 0.0660465509749711 0.000704686244275338 0.176882938102508 0.134254150019803 0.00301700767902668 0.00146559050061717 0.617629076478799 0.391796497651864 0.391796497651864 -0.4800274905879333
347 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 17.10338647 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.842058839093973 0.180962520579808 0.000840183131263393 0.0600498448220066 0.0139903797423045 0.00230022430813273 0.00221494849849946 0.739641898917986 0.515169720881209 0.515169720881209 -0.3039448947184272
348 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.07758774 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.48897339158558 0.000136174132145422 0.00212452688507234 0.811633900204502 0.179761878637886 0.00385751556458306 0.00248600457581157 0.0 0.767759892635294 0.767759892635294 1.24980418110703
349 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.50454535 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ALA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.675628649636653 0.00268100351583557 0.00240431632025112 0.142040711181502 0.523320437165769 0.324868931367264 0.00468460044937817 0.0 0.0241897161135915 0.0241897161135915 -0.7344067258409619
350 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.59671966 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence SER Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.737600973168581 0.00157432110064945 0.00176844882817444 0.053765469363115 0.438156626388713 0.500533090562106 0.00420204375724176 0.0 0.0189624719731265 0.0189624719731265 -0.7483555838832638
351 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.07758774 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.48897339158558 0.0550309639531662 0.00234353835896855 0.320198252727196 0.282656133384496 0.0064798077198827 0.00202476215621646 0.331266541700075 1.20135127285815 1.20135127285815 0.6753975083349388
352 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.50454535 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ALA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.675628649636653 0.0418659426619505 0.0219153925677162 0.21668759621254 0.199875450362037 0.113029824089051 0.0495629458661235 0.357062848240582 0.0027707272238572 0.0027707272238572 -1.035258728972282
353 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.59671966 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence SER Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.737600973168581 0.0234118812216689 0.0071462713755353 0.0426958781226752 0.0464078935005845 0.0346044033846598 0.0235967118628926 0.822136960531984 0.0055457738057274 0.0055457738057274 -1.0312980850577906
354 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.16930088 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence TZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 5.001930853466109 0.00767358537807448 0.00233215653996207 0.0713684727707158 0.307444763898641 0.0172788380976704 0.00511228295653041 0.588789900358405 0.0063917829512014 0.0063917829512014 -1.0300906311016962
355 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.579236803961587 0.00833063062779389 0.00173987762429209 0.156651961849343 0.112205138324295 0.00895304009765426 0.00427289873828259 0.707846452738339 0.269390835357988 0.269390835357988 -0.6547291495189385
356 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.15847938 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence 3F Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.484131857611035 0.0158311033527607 0.00109353847138243 0.0200990623529318 0.00589717673503959 0.00332080816189693 0.00297802720282806 0.95078028372316 0.0070114291767852 0.0070114291767852 -1.0292062502525494
357 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81395289 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PYR Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 5.0755487449389 0.0138253404297663 0.00670375922221507 0.064918033729737 0.0310082272870404 0.0307691214666871 0.0156091189056244 0.83716639895893 0.0111434256880136 0.0111434256880136 -1.023308919755896
358 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.99522451 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.402809173856411 4.40280917385641 0.0144051248882893 0.000525788660297221 0.125667067331117 0.214373546599095 0.00410880851120861 0.00177167337754258 0.639147990632451 0.176512628889736 0.176512628889736 -0.7872881867764152
359 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.16930088 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence TZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 5.001930853466109 0.00115119797114568 0.0003959818507672 0.0538124209539168 0.93604524664705 0.00736502972190904 0.00123012285521143 0.0 0.0261518819859255 0.0261518819859255 -0.7291707023316024
360 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.579236803961587 0.0010942059599737 0.000714578151988552 0.367034511120116 0.62078160479883 0.0079478856978032 0.00242721427128835 0.0 0.970510173989973 0.970510173989973 1.7908416411254202
361 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.15847938 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence 3F Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.484131857611035 0.0376230130625874 0.00236009027623813 0.247039705692743 0.697452972603375 0.0104681865382628 0.00505603182679352 0.0 0.0013884403431976 0.0013884403431976 -0.7952517429011965
362 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81395289 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PYR Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 5.0755487449389 0.00873826813676438 0.00145112475939544 0.193065080283125 0.778197018798523 0.014433213681334 0.00411529434085825 0.0 0.165721665234437 0.165721665234437 -0.35672988242469916
363 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.99522451 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.402809173856411 4.40280917385641 0.00532422079532615 0.00061084449763591 0.522469676271313 0.459778984209221 0.00966894873803684 0.00214732548846694 0.0 0.161020662402855 0.161020662402855 -0.3692744698577941
364 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.584763376210429 0.0318391346416656 0.000341552225113717 0.113678281409446 0.242279767731552 0.00387550619454475 0.000871625110337537 0.60711413268734 0.649833386251602 0.649833386251602 -0.11174818341388475
365 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.746322465743975 0.0548193142492001 0.000263362025026913 0.0902956804122817 0.160837629010128 0.00315355508353847 0.000739500993108033 0.689890958226717 1.16375238999006 1.16375238999006 0.6217350625958049
366 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O DSPC 0 0 1 0 16.87346518 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence HIS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.651385609785055 4.651385609785054 0.0172566765287249 0.00318344365411915 0.0712890876960715 0.171965068058214 0.0218135302099503 0.0115493777455846 0.702942816107335 0.00327405282427 0.00327405282427 -1.0345403650034368
367 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.584763376210429 0.000599963927151076 0.000397997752734626 0.420976508827142 0.560178394908249 0.017044159994242 0.000802974590480822 0.0 0.25255828640642 0.25255828640642 -0.1250070722684871
368 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.746322465743975 0.000524374578838527 0.00061514916196369 0.547432124587029 0.435435317287124 0.015309113403191 0.000683920981854007 0.0 0.568394489552276 0.568394489552276 0.7177992409467366
369 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O DSPC 0 0 1 0 16.87346518 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence HIS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.651385609785055 4.651385609785054 0.00171983501988967 0.00189561016704693 0.0120716635806003 0.711278646835123 0.270438826106656 0.00259541829068387 0.0 0.0112897234542117 0.0112897234542117 -0.7688302502674332
370 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.484733632866144 0.0047850951415261 0.000675911772575438 0.46069265034102 0.522359359837259 0.0109775121699624 0.00050947073765779 0.0 0.773205414607926 0.773205414607926 1.2643355117511204
371 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.633757642840004 0.00198911414189635 0.00126811595413123 0.543867583730296 0.438842770521552 0.0129988635137729 0.00103355213835123 0.0 1.98493053910539 1.98493053910539 4.497814051056962
372 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.0333911 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.609759638321899 0.00125031423153586 0.0004860362025215 0.538249539726811 0.445414640899446 0.0137801694455006 0.000819299494184621 0.0 0.291137444797345 0.291137444797345 -0.022058905064912687
373 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 16.68738808 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.392884144674663 0.00226285185388551 0.000562872305858137 0.731364439797527 0.256932619347553 0.00825451238600619 0.000622704309170273 0.0 1.82872279459479 1.82872279459479 4.080974968218046
374 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.484733632866144 0.0442923458834068 0.00055452650331333 0.106459881295074 0.192526940733964 0.00311682882196998 0.000623042068808978 0.652426434693463 0.672431538902446 0.672431538902446 -0.07949530652163618
375 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.633757642840004 0.0374610013402809 0.0005350551106764 0.260855439538844 0.469905543128085 0.00469334055693451 0.000912093945676405 0.225637526379503 1.69276100831231 1.69276100831231 1.3767547363410753
376 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.0333911 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.609759638321899 0.0836645231428707 0.000419599806684375 0.0235684307001288 0.0712275212970175 0.00119681308497475 0.00178295859414992 0.818140153374174 0.426058290183635 0.426058290183635 -0.431127857343191
377 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 16.68738808 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.392884144674663 0.0512990735432809 0.000672189655491244 0.187343972483681 0.232187436433234 0.00314791870850824 0.00146679734452725 0.523882611831278 1.30784095113947 1.30784095113947 0.8273833160675146
378 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 17.78759767 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.751259891859986 0.00405799702984203 0.00225047224182105 0.719270208750414 0.257208699720685 0.0138718178214465 0.00334080443579049 0.0 1.25160610942024 1.25160610942024 2.540943835364252
379 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.31729774 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.666265285347902 0.00272982965803786 0.000172365352517303 0.498048022051036 0.479137442306018 0.0180316959727267 0.00188064465966415 0.0 0.155537169131505 0.155537169131505 -0.3839071266005448
380 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.71419039 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.904756125442696 0.00273286200255075 0.00260055069792003 0.431146257918051 0.50349018951458 0.0550138028095967 0.00501633705730229 0.0 0.021985308799366 0.021985308799366 -0.7402891686477768
381 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.733211535868976 4.733211535868975 0.00166528576158017 0.000176886038620712 0.205207225042143 0.750916028545382 0.0392720451710516 0.00276252944122191 0.0 0.120096690961961 0.120096690961961 -0.478479751420455
382 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 18.70678989 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.858726543710496 0.00383743159330312 0.00248950729214128 0.555903422423481 0.380445635709031 0.0515668712566801 0.00575713172536402 0.0 0.0526538412251038 0.0526538412251038 -0.6584504418393717
383 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.31729774 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.666265285347902 0.0567289157085495 0.00653348267008008 0.064839577285576 0.335055277453961 0.0144955694225392 0.0143736618741762 0.507973515585118 0.268311366051918 0.268311366051918 -0.6562698060131026
384 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.71419039 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.904756125442696 0.0248552898268163 0.0125192728735768 0.0725307642598596 0.0355254691282667 0.0214395648154144 0.0248745799236939 0.808255059172372 0.0741845243461588 0.0741845243461588 -0.9333344503561898
385 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.733211535868976 4.733211535868975 0.0883917007893502 0.00174599838911923 0.0536405332414895 0.100118671210748 0.00771990063396103 0.00639776118235737 0.741985434552974 0.528035509086713 0.528035509086713 -0.28558239006925334
386 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 18.70678989 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.858726543710496 0.0175679405294797 0.00960173891174304 0.0903179131752613 0.0388184937379254 0.0182497546285787 0.0249045868533177 0.800539572163694 0.125181510399577 0.125181510399577 -0.8605497613389135
387 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.62870578 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.765586907393996 0.00159278655447388 0.00186611160196327 0.488795918944862 0.485247409700546 0.018616198181097 0.00388157501705755 0.0 0.352570746370957 0.352570746370957 0.14187535545424673
388 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.61880246 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.82374330878754 0.000875415234709484 0.00127375854285246 0.683377837104949 0.304003257921165 0.00820355561270421 0.00226617558361995 0.0 0.943420561172443 0.943420561172443 1.7185532318874628
389 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.433313679041901 0.000602190120987361 0.000576528881915898 0.00566197423128506 0.0161763859347042 0.971683265119797 0.00529965571131053 0.0 0.0305789310371634 0.0305789310371634 -0.7173571583105779
390 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.70929826 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.356324137321509 0.00187378052819512 0.00157654975652554 0.0163863796216318 0.0648246159165097 0.905280007427939 0.0100586667491993 0.0 0.003875136361479 0.003875136361479 -0.7886160150068647
391 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.17273956 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.440767129696482 4.440767129696481 0.00301049906217731 9.21592223531261e-05 0.00380096827414773 0.0130323481002541 0.97657327492354 0.00349075041752818 0.0 0.0274401441027376 0.0274401441027376 -0.7257329854571254
392 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 18.38469122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.349632566862877 0.00273989274094748 0.00161018393061426 0.0112824839963327 0.0583352940699212 0.919247401685963 0.00678474357622127 0.0 0.0081601896883771 0.0081601896883771 -0.7771813854096181
393 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 18.90345652 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.662778498608405 0.00349315451118928 0.00171298178399312 0.037797325974731 0.242816837972913 0.706569889763285 0.00760980999388795 0.0 0.0136767051395404 0.0136767051395404 -0.7624606092513427
394 O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN DSPC 0 0 1 0 18.38469122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 0 0 1 4.405498990859024 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
395 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 16.89527599 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 4.815106909815019 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
396 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.89527599 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.562053894914463 0.00241700650155169 0.00189161759954923 0.0117804592312353 0.0588098364115177 0.918016488291877 0.0070845919642692 0.0 0.288385322760908 0.288385322760908 -0.029402920107978105
397 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.89527599 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.667205576907544 0.00146771264056884 0.000853267380299107 0.00521853383313367 0.0984194458399351 0.890752405611161 0.00328863469490281 0.0 0.174730948641107 0.174730948641107 -0.3326886836733955
398 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 17.94799221 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.701389043728634 0.00256320924432886 0.00193796271600952 0.0128146756680969 0.0418402586947232 0.934553052894321 0.00629084078252029 0.0 0.0492674291707299 0.0492674291707299 -0.6674870545840368
399 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 18.38469122 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.460491174618648 0.00101051612937229 0.00153512067382825 0.00950098551353592 0.161931963893941 0.822835993399315 0.00318542039000704 0.0 0.105055900803977 0.105055900803977 -0.5186159763833679
400 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 19.0764718 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.505460341839079 0.00282763425766742 0.00135220428389579 0.101550310310828 0.701364372579719 0.18950529802972 0.00340018053817036 0.0 0.0700302222351868 0.0700302222351868 -0.6120817118766197
401 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 17.18453431 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.684905154006945 0.0025903109842197 0.00122267327648511 0.0959380417500791 0.558064631213231 0.339326541744348 0.00285780103163663 0.0 0.0836567108446898 0.0836567108446898 -0.5757195389760648
402 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 18.58497913 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.695924549256556 0.00270162630925447 0.000571977156802491 0.072649821877092 0.283620916967858 0.638520904456637 0.00193475323235631 0.0 0.108372702997361 0.108372702997361 -0.5097651169808466
403 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O DSPC 0 0 1 0 16.82518306 0.485 48.5 0.1 10.0 0.4 40.0 0.015 1.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence LYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 4.202899968776446 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
404 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.52948326 0.4325 43.25 0.25 25.0 0.3 30.0 0.0175 1.75 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 5.029784112935016 0.000951862951033406 0.000642237882584555 0.00747953132811133 0.295137112679544 0.692754163229738 0.0030350919289883 0.0 0.19435393861906 0.19435393861906 -0.2803248961378029
405 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 11.10169345 0.3 30.0 0.25 25.0 0.425 42.5 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.833102254034098 0.00529626249319983 0.00246267213977097 0.0289260006923807 0.563065088278535 0.393847703229461 0.00640227316665243 0.0 0.049072760763369 0.049072760763369 -0.6680065256297026
406 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.72804315 0.38075000000000003 38.075 0.17975000000000002 17.975 0.41825 41.825 0.02125 2.125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 4.93014804318357 4.930148043183569 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
407 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.39261658 0.37 37.0 0.25 25.0 0.37 37.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 5.146912912388804 5.146912912388803 0.000759366167023555 0.000694817987152034 0.00466364025695932 0.212680085653105 0.777593147751606 0.00360894218415418 0.0 0.201238755105862 0.201238755105862 -0.2619528199077537
408 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.51039532 0.385 38.5 0.205 20.5 0.385 38.5 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.684905154006945 0.00157535225652128 0.00592927130077556 0.00900517890128691 0.366135503933579 0.613833328839362 0.00352136476847493 0.0 0.149329656900936 0.149329656900936 -0.40047182198750214
409 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.48290639 0.45 45.0 0.09 9.0 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.869839484130799 0.00147117555088917 0.000927103843315829 0.00585237061645294 0.136146016514374 0.851575135737455 0.00402819773751327 0.0 0.31219703699332 0.31219703699332 0.034138443686487704
410 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.13138042 0.41200000000000003 41.2 0.2235 22.35 0.34325000000000006 34.325 0.02125 2.125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 4.901564199041894 0.00315707422768752 0.0025689389054212 0.0146712017391132 0.327849346901905 0.646061693847123 0.0056917443787501 0.0 0.158541375998041 0.158541375998041 -0.3758904252594646
411 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.11942242 0.41825 41.825 0.14975 14.975 0.41825 41.825 0.01375 1.375 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 5.039546637590676 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
412 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.79492927 0.45 45.0 0.225 22.5 0.3 30.0 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.9141243937154115 0.00113350028034128 0.000566939752127873 0.00680706926467914 0.502661298625749 0.486733894218144 0.00209729785895866 0.0 0.145448415448628 0.145448415448628 -0.4108288829150842
413 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 12.55393718 0.34325000000000006 34.325 0.21725000000000003 21.725 0.41825 41.825 0.02125 2.125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 4.814620410170298 0.001692878443667 0.000820135726038303 0.00868136575507882 0.408928448915581 0.577101122031978 0.00277604912765729 0.0 0.113760366510672 0.113760366510672 -0.495388181160095
414 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.93959861 0.45 45.0 0.075 7.5 0.45 45.0 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.527640983478854 0.00506334343919377 0.004281344333051 0.0165771717732586 0.226890591170162 0.736348900590883 0.0108386486934518 0.0 0.0547343765642327 0.0547343765642327 -0.6528985503803821
415 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.59337013 0.45 45.0 0.1575 15.75 0.375 37.5 0.0175 1.75 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.810557015713042 0.00141112235558708 0.000749767156842064 0.00637541161251223 0.138880841494329 0.847648476304751 0.00493438107597822 0.0 0.294154433878409 0.294154433878409 -0.0140080944893819
416 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 11.66031337 0.3 30.0 0.24 24.0 0.45 45.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 5.167639042905921 5.16763904290592 0.00199236267032557 0.000827577235394216 0.008719084857644 0.192132365846187 0.792330257640873 0.0039983517495764 0.0 0.151793984465988 0.151793984465988 -0.3938957841268362
417 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.66358165 0.375 37.5 0.15 15.0 0.45 45.0 0.025 2.5 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.618086411254637 0.00271480786609193 0.00181664538344774 0.00938513027274936 0.132547184736695 0.849509595736892 0.0040266360041233 0.0 0.0950036114384557 0.0950036114384557 -0.5454404279666308
418 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.26186294 0.45 45.0 0.24 24.0 0.3 30.0 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 5.098035484377089 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
419 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.27611859 0.45 45.0 0.11381999999999999 11.382 0.42618 42.618 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.680277658474897 4.680277658474896 0.00152924607683628 0.00192508702614222 0.0105762053188716 0.167270255683968 0.810875386281306 0.00782381961287527 0.0 0.278754923842637 0.278754923842637 -0.05510156049896443
420 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.11001923 0.45 45.0 0.13445000000000001 13.445 0.40445 40.445 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.924350925499243 0.000999438616070677 0.00125158481927741 0.00771842730472846 0.249469737208587 0.735450494958472 0.00511031709286499 0.0 0.286455906115286 0.286455906115286 -0.03455155257492116
421 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.85662691 0.45 45.0 0.16405 16.405 0.37595 37.595 0.01 1.0 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.924350925499243 0.00141338619768439 0.00124322063420737 0.0100450891793794 0.235894751086175 0.745556785166654 0.00584676773589971 0.0 0.264336417833639 0.264336417833639 -0.09357722532293417

2
docker-compose-gpu.yml
View File

@ -35,7 +35,7 @@ services:
target: streamlit
container_name: lnp-streamlit
ports:
- "8501:8501"
- "18501:8501"
environment:
- API_URL=http://api:8000
depends_on:

10
models/benchmark/config.json
View File

@ -5,8 +5,14 @@
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": false,
"mpnn_ensemble_paths": null,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,

68
models/benchmark/cv_results.json Normal file
View File

@ -0,0 +1,68 @@
{
"fold_results": [
{
"fold_idx": 0,
"best_val_loss": 0.866959414306682,
"best_val_rmse": 0.939569308267399,
"best_val_r2": 0.24210831047556391,
"epochs_trained": 21
},
{
"fold_idx": 1,
"best_val_loss": 0.7120698080343358,
"best_val_rmse": 0.89035723356781,
"best_val_r2": 0.1949605134929706,
"epochs_trained": 15
},
{
"fold_idx": 2,
"best_val_loss": 0.7995324550767853,
"best_val_rmse": 0.9427014903075246,
"best_val_r2": 0.14637384616637905,
"epochs_trained": 18
},
{
"fold_idx": 3,
"best_val_loss": 0.7464333962453039,
"best_val_rmse": 0.8886072948338112,
"best_val_r2": 0.16404373856430554,
"epochs_trained": 16
},
{
"fold_idx": 4,
"best_val_loss": 0.7502263283314047,
"best_val_rmse": 0.88562010695961,
"best_val_r2": 0.09823831053676024,
"epochs_trained": 11
}
],
"summary": {
"val_loss_mean": 0.7750442803989024,
"val_loss_std": 0.053755669741545144,
"val_rmse_mean": 0.9093710867872311,
"val_rmse_std": 0.0259985349306361,
"val_r2_mean": 0.16914494384719586,
"val_r2_std": 0.048088236270900114
},
"config": {
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,
"epochs": 50,
"patience": 10
}
}

170
models/benchmark/fold_0/history.json Normal file
View File

@ -0,0 +1,170 @@
[
{
"epoch": 1,
"train_loss": 0.7899117102249027,
"val_loss": 0.9106255005528325,
"val_rmse": 0.9542669915061958,
"val_r2": 0.218211451466231,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6509626604859896,
"val_loss": 0.904300603615648,
"val_rmse": 0.9509472242536414,
"val_r2": 0.22364146549089958,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.5816657132710804,
"val_loss": 0.9535427025920375,
"val_rmse": 0.9764951165159946,
"val_r2": 0.18136623613531166,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5494824945224491,
"val_loss": 0.9088308029281216,
"val_rmse": 0.9533261696672906,
"val_r2": 0.219752238617257,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5085460379524128,
"val_loss": 0.8783120935910861,
"val_rmse": 0.9371830584412856,
"val_r2": 0.24595309834595658,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.48759515778619567,
"val_loss": 0.9145861336527745,
"val_rmse": 0.95633996508362,
"val_r2": 0.2148111719235638,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.4649609710302709,
"val_loss": 0.8910244694664913,
"val_rmse": 0.9439409210372551,
"val_r2": 0.2350392911253747,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.45096972002922103,
"val_loss": 0.9157029792612511,
"val_rmse": 0.9569237087861149,
"val_r2": 0.21385233105727164,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.4470898296366794,
"val_loss": 0.8871119191512843,
"val_rmse": 0.9418661912008598,
"val_r2": 0.23839827812681513,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4263995984354151,
"val_loss": 0.9026704432377626,
"val_rmse": 0.9500897031987177,
"val_r2": 0.225041003980039,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.42710590581226254,
"val_loss": 0.866959414306682,
"val_rmse": 0.9311065501955652,
"val_r2": 0.25569957823995526,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.41655660829171715,
"val_loss": 0.9008103422506007,
"val_rmse": 0.9491102873618649,
"val_r2": 0.2266379392872636,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.3916222040087877,
"val_loss": 0.9101736657006892,
"val_rmse": 0.9540302227850528,
"val_r2": 0.21859935152562493,
"lr": 0.0001
},
{
"epoch": 14,
"train_loss": 0.3856295347614988,
"val_loss": 0.9106341469920588,
"val_rmse": 0.954271527471978,
"val_r2": 0.21820401921809762,
"lr": 0.0001
},
{
"epoch": 15,
"train_loss": 0.3810926664962948,
"val_loss": 0.9611411314677847,
"val_rmse": 0.980378056981909,
"val_r2": 0.1748428526041309,
"lr": 0.0001
},
{
"epoch": 16,
"train_loss": 0.3807094296354591,
"val_loss": 0.8823861818405629,
"val_rmse": 0.939354131279333,
"val_r2": 0.2424554103126585,
"lr": 0.0001
},
{
"epoch": 17,
"train_loss": 0.37233418258341505,
"val_loss": 0.918043110101732,
"val_rmse": 0.958145661422436,
"val_r2": 0.21184329197961715,
"lr": 0.0001
},
{
"epoch": 18,
"train_loss": 0.335445166938195,
"val_loss": 0.8913753229688821,
"val_rmse": 0.9441267531140994,
"val_r2": 0.23473806839649425,
"lr": 5e-05
},
{
"epoch": 19,
"train_loss": 0.31598393516242,
"val_loss": 0.8946952256492021,
"val_rmse": 0.9458832970615956,
"val_r2": 0.23188788612140665,
"lr": 5e-05
},
{
"epoch": 20,
"train_loss": 0.3115269015610559,
"val_loss": 0.8904139892758737,
"val_rmse": 0.9436174963162874,
"val_r2": 0.23556340193241154,
"lr": 5e-05
},
{
"epoch": 21,
"train_loss": 0.31039785354757743,
"val_loss": 0.8827904894570534,
"val_rmse": 0.939569308267399,
"val_r2": 0.24210831047556391,
"lr": 5e-05
}
]

BIN
models/benchmark/fold_0/loss_curves.png Normal file
View File

Binary file not shown.
Side by Side

After

Width:  |  Height:  |  Size: 90 KiB

3
models/benchmark/fold_0/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:ab5ae6c172dec6bbc469ed791c33fd1c572e74a981a6b23999930c81da84834c
size 28583980

122
models/benchmark/fold_1/history.json Normal file
View File

@ -0,0 +1,122 @@
[
{
"epoch": 1,
"train_loss": 0.7453622951738345,
"val_loss": 0.7287117057540469,
"val_rmse": 0.8536461223443813,
"val_r2": 0.25997848961785786,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6202318301783801,
"val_loss": 0.8348047510389204,
"val_rmse": 0.9136765048950971,
"val_r2": 0.1522388425330945,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.5613789587632281,
"val_loss": 0.7393429625145053,
"val_rmse": 0.859850541336497,
"val_r2": 0.24918223840017484,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5340799972517996,
"val_loss": 0.7914513284207867,
"val_rmse": 0.8896355040908644,
"val_r2": 0.19626512520609807,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5159078478101362,
"val_loss": 0.7120698080343358,
"val_rmse": 0.8438422868458092,
"val_r2": 0.2768786736118508,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.48152070701834093,
"val_loss": 0.7668712777619022,
"val_rmse": 0.8757118747256214,
"val_r2": 0.22122665690371812,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.45984981542934344,
"val_loss": 0.7360424780624201,
"val_rmse": 0.8579291823413716,
"val_r2": 0.25253393415943515,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.45007407635281776,
"val_loss": 0.7562788616393004,
"val_rmse": 0.8696429505509381,
"val_r2": 0.23198348039372452,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.4460098036125274,
"val_loss": 0.7949708888036179,
"val_rmse": 0.8916114012161344,
"val_r2": 0.1926909400069966,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.43397492979548397,
"val_loss": 0.7239050103783976,
"val_rmse": 0.8508260793618692,
"val_r2": 0.264859775574553,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.4115098984379352,
"val_loss": 0.791457345131381,
"val_rmse": 0.8896388831206279,
"val_r2": 0.19625901967364356,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.37194536275117374,
"val_loss": 0.7726255914744209,
"val_rmse": 0.8789912374883786,
"val_r2": 0.21538304039734912,
"lr": 5e-05
},
{
"epoch": 13,
"train_loss": 0.3584992554411058,
"val_loss": 0.7775832472570909,
"val_rmse": 0.8818068116885781,
"val_r2": 0.2103484386148572,
"lr": 5e-05
},
{
"epoch": 14,
"train_loss": 0.3541459802334448,
"val_loss": 0.7248780828880452,
"val_rmse": 0.851397724648248,
"val_r2": 0.2638716050714508,
"lr": 5e-05
},
{
"epoch": 15,
"train_loss": 0.34343952732892397,
"val_loss": 0.7927360100273746,
"val_rmse": 0.89035723356781,
"val_r2": 0.1949605134929706,
"lr": 5e-05
}
]

BIN
models/benchmark/fold_1/loss_curves.png Normal file
View File

Binary file not shown.
Side by Side

After

Width:  |  Height:  |  Size: 95 KiB

3
models/benchmark/fold_1/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:e8833c5595cb93d94c708ae2aa4f362601b966efac63bc6ead34e26a8c615759
size 28583980

146
models/benchmark/fold_2/history.json Normal file
View File

@ -0,0 +1,146 @@
[
{
"epoch": 1,
"train_loss": 0.8005930782125189,
"val_loss": 0.8978909060375992,
"val_rmse": 0.9475710597900247,
"val_r2": 0.13753217578760868,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6647633858067866,
"val_loss": 0.9069839662945529,
"val_rmse": 0.9523570524949272,
"val_r2": 0.12879786730301723,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6120032529657482,
"val_loss": 0.8839158257097856,
"val_rmse": 0.9401679753583908,
"val_r2": 0.15095592977292416,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5758675443722933,
"val_loss": 0.8241970924790121,
"val_rmse": 0.9078530050429938,
"val_r2": 0.2083186825092379,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5518687241535394,
"val_loss": 0.8732806970211364,
"val_rmse": 0.9344948904182305,
"val_r2": 0.16117148058432484,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.5352233096186949,
"val_loss": 0.9003329171693991,
"val_rmse": 0.948858741688057,
"val_r2": 0.1351865178108379,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5072678237982289,
"val_loss": 0.8956774030063416,
"val_rmse": 0.9464023429479049,
"val_r2": 0.1396583679059904,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.48632043020011667,
"val_loss": 0.7995324550767853,
"val_rmse": 0.8941657905362718,
"val_r2": 0.23201024562997075,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.476851694737564,
"val_loss": 0.9313454642942857,
"val_rmse": 0.9650624096991449,
"val_r2": 0.10539746433898978,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4651990471254433,
"val_loss": 0.9388355878495028,
"val_rmse": 0.9689352972912508,
"val_r2": 0.09820280604253973,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.4542714411008868,
"val_loss": 0.9288384820607533,
"val_rmse": 0.9637626636776235,
"val_r2": 0.1078055429771394,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.4351121415054258,
"val_loss": 0.8265697369893573,
"val_rmse": 0.909158813059214,
"val_r2": 0.2060396191034739,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.4299718189863316,
"val_loss": 0.875909022043885,
"val_rmse": 0.9359001171460944,
"val_r2": 0.15864684289305642,
"lr": 0.0001
},
{
"epoch": 14,
"train_loss": 0.4181867929766265,
"val_loss": 0.8250082328898605,
"val_rmse": 0.90829963810367,
"val_r2": 0.20753952988126345,
"lr": 0.0001
},
{
"epoch": 15,
"train_loss": 0.373523000458965,
"val_loss": 0.8749000746820509,
"val_rmse": 0.9353609401890938,
"val_r2": 0.15961597956698637,
"lr": 5e-05
},
{
"epoch": 16,
"train_loss": 0.3671811397241496,
"val_loss": 0.9015646148027009,
"val_rmse": 0.9495075636176421,
"val_r2": 0.1340034085263745,
"lr": 5e-05
},
{
"epoch": 17,
"train_loss": 0.3561463250274025,
"val_loss": 0.9034364934726071,
"val_rmse": 0.9504927677633731,
"val_r2": 0.13220536900740842,
"lr": 5e-05
},
{
"epoch": 18,
"train_loss": 0.35193108026016723,
"val_loss": 0.8886860885669051,
"val_rmse": 0.9427014903075246,
"val_r2": 0.14637384616637905,
"lr": 5e-05
}
]

BIN
models/benchmark/fold_2/loss_curves.png Normal file
View File

Binary file not shown.
Side by Side

After

Width:  |  Height:  |  Size: 94 KiB

3
models/benchmark/fold_2/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:20f9fca9b0979cd6b1944782dedd1de767bbc680b0657669fdf8a33a15e7fe79
size 28583980

130
models/benchmark/fold_3/history.json Normal file
View File

@ -0,0 +1,130 @@
[
{
"epoch": 1,
"train_loss": 0.8148546263460803,
"val_loss": 0.7861085421160647,
"val_rmse": 0.886627616383139,
"val_r2": 0.16776434979300892,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6945673692072785,
"val_loss": 0.761581165069028,
"val_rmse": 0.8726861787844787,
"val_r2": 0.19373092504438605,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6379185403627962,
"val_loss": 0.7770084098765725,
"val_rmse": 0.8814808129559957,
"val_r2": 0.17739843055843074,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.6046393075286077,
"val_loss": 0.7532169644769869,
"val_rmse": 0.8678807289256297,
"val_r2": 0.20258592532118047,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.574669826439149,
"val_loss": 0.76201491355896,
"val_rmse": 0.8729346508809308,
"val_r2": 0.19327173618113946,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.548684894293898,
"val_loss": 0.7464333962453039,
"val_rmse": 0.8639637668091451,
"val_r2": 0.20976753953251948,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5225494998151095,
"val_loss": 0.7919017117274435,
"val_rmse": 0.8898885912807352,
"val_r2": 0.1616312442777017,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.5012204889211006,
"val_loss": 0.7951003655007011,
"val_rmse": 0.8916840115687831,
"val_r2": 0.1582448816658284,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.4793119378553028,
"val_loss": 0.7533921110002618,
"val_rmse": 0.8679816385432312,
"val_r2": 0.20240048180423054,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4765514090116268,
"val_loss": 0.7677806145266483,
"val_rmse": 0.87623091439625,
"val_r2": 0.18716770632348811,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.45838247044045616,
"val_loss": 0.7562473639061577,
"val_rmse": 0.8696248438991365,
"val_r2": 0.1993776980696037,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.44503072581912445,
"val_loss": 0.78564125236712,
"val_rmse": 0.8863640590634866,
"val_r2": 0.16825905397921426,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.4123238583424547,
"val_loss": 0.8002189915431174,
"val_rmse": 0.8945495972571591,
"val_r2": 0.15282592768621528,
"lr": 5e-05
},
{
"epoch": 14,
"train_loss": 0.3929443174135042,
"val_loss": 0.7628068139678553,
"val_rmse": 0.8733881274466063,
"val_r2": 0.19243335180866483,
"lr": 5e-05
},
{
"epoch": 15,
"train_loss": 0.3890129279157341,
"val_loss": 0.8002446143250717,
"val_rmse": 0.8945639305883649,
"val_r2": 0.1527987789984585,
"lr": 5e-05
},
{
"epoch": 16,
"train_loss": 0.3771514101854083,
"val_loss": 0.7896229298491227,
"val_rmse": 0.8886072948338112,
"val_r2": 0.16404373856430554,
"lr": 5e-05
}
]

BIN
models/benchmark/fold_3/loss_curves.png Normal file
View File

Binary file not shown.
Side by Side

After

Width:  |  Height:  |  Size: 93 KiB

3
models/benchmark/fold_3/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:0dec915990fbde0058dc25f68d184933ebc600a77d00eb8822e94741c62e09ab
size 28583980

90
models/benchmark/fold_4/history.json Normal file
View File

@ -0,0 +1,90 @@
[
{
"epoch": 1,
"train_loss": 0.8393314411765651,
"val_loss": 0.7502263283314047,
"val_rmse": 0.8661560636423644,
"val_r2": 0.13744033734121908,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.7042063907573097,
"val_loss": 0.7743279527786847,
"val_rmse": 0.8799590633936856,
"val_r2": 0.10972991152918976,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6433535717035594,
"val_loss": 0.8280804295881039,
"val_rmse": 0.9099892385624878,
"val_r2": 0.04792895490030091,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.586733216988413,
"val_loss": 0.7648866772212758,
"val_rmse": 0.8745779913632254,
"val_r2": 0.120584870710571,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5605123582639192,
"val_loss": 0.8489922429263504,
"val_rmse": 0.9214077527868639,
"val_r2": 0.02388593930542382,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.5282266008226495,
"val_loss": 0.78830553962866,
"val_rmse": 0.8878657251158053,
"val_r2": 0.09365941770731201,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5189776589995936,
"val_loss": 0.7757515833549893,
"val_rmse": 0.8807676096099809,
"val_r2": 0.1080931189893013,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.46074101015141133,
"val_loss": 0.8642474814890996,
"val_rmse": 0.9296491244907108,
"val_r2": 0.00634648367115187,
"lr": 5e-05
},
{
"epoch": 9,
"train_loss": 0.4493268092996196,
"val_loss": 0.7575331367241382,
"val_rmse": 0.8703637959569727,
"val_r2": 0.1290394588682955,
"lr": 5e-05
},
{
"epoch": 10,
"train_loss": 0.4392915386902659,
"val_loss": 0.7912215596329188,
"val_rmse": 0.8895063585101289,
"val_r2": 0.09030677906557705,
"lr": 5e-05
},
{
"epoch": 11,
"train_loss": 0.42733028860468614,
"val_loss": 0.7843229835400349,
"val_rmse": 0.88562010695961,
"val_r2": 0.09823831053676024,
"lr": 5e-05
}
]

BIN
models/benchmark/fold_4/loss_curves.png Normal file
View File

Binary file not shown.
Side by Side

After

Width:  |  Height:  |  Size: 91 KiB

3
models/benchmark/fold_4/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:073262de4065ac333aa0a59ca7649c083e57b34b364e529ce105a2d59ce57d64
size 28583980

63
models/benchmark/test_results.json Normal file
View File

@ -0,0 +1,63 @@
{
"fold_results": [
{
"fold_idx": 0,
"n_samples": 2037,
"mse": 0.7226313117346976,
"rmse": 0.8500772386875781,
"mae": 0.6242580430768412,
"r2": 0.16916722542340512,
"correlation": 0.4730393645703907
},
{
"fold_idx": 1,
"n_samples": 1658,
"mse": 0.9158973512242636,
"rmse": 0.9570252615392467,
"mae": 0.7200029971805739,
"r2": 0.21368546363481555,
"correlation": 0.4973138359369983
},
{
"fold_idx": 2,
"n_samples": 1615,
"mse": 0.7387503133202947,
"rmse": 0.8595058541512645,
"mae": 0.6402343517433183,
"r2": 0.24978407645589784,
"correlation": 0.5249250503279256
},
{
"fold_idx": 3,
"n_samples": 1754,
"mse": 0.9009732149716101,
"rmse": 0.949196088788618,
"mae": 0.70815324582605,
"r2": 0.134571475403793,
"correlation": 0.4336201644807484
},
{
"fold_idx": 4,
"n_samples": 1520,
"mse": 0.7580491877309711,
"rmse": 0.870660202220689,
"mae": 0.653891459692654,
"r2": 0.1974701527113163,
"correlation": 0.488930703580102
}
],
"summary_stats": {
"rmse_mean": 0.8972929290774792,
"rmse_std": 0.046105045536526425,
"r2_mean": 0.19293567872584555,
"r2_std": 0.03912588645481614
},
"overall": {
"n_samples": 8584,
"mse": 0.8057061196128802,
"rmse": 0.8976113410674356,
"mae": 0.6681468887523418,
"r2": 0.19429387403723375,
"correlation": 0.4821095149481418
}
}

11
models/final/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.14731648771233646,
"lr": 0.00010399668603456206,
"weight_decay": 0.0007696017715340258,
"backbone_lr_ratio": 0.7472270478607838,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

17
models/final/class_weights.json Normal file
View File

@ -0,0 +1,17 @@
{
"pdi": [
0.011065198108553886,
0.03264812380075455,
0.8369068503379822,
3.119379997253418
],
"ee": [
1.600011944770813,
0.9947696924209595,
0.40521833300590515
],
"toxic": [
0.09425132721662521,
1.9057486057281494
]
}

1
models/final/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 23}

832
models/final/history.json
View File

@ -1,720 +1,212 @@
{
"train": [
{
"loss": 16.125412720900314,
"loss_size": 10.958004199541532,
"loss_pdi": 1.2954746576455922,
"loss_ee": 1.032385032910567,
"loss_delivery": 0.9622580982171572,
"loss_biodist": 1.3037926875627959,
"loss_toxic": 0.5734981435995835
"loss": 17.60348994391305,
"loss_size": 12.354392801012311,
"loss_pdi": 1.4643298983573914,
"loss_ee": 1.090087456362588,
"loss_delivery": 0.8421656531946999,
"loss_biodist": 1.23681207214083,
"loss_toxic": 0.6157020671027047
},
{
"loss": 5.045667318197397,
"loss_size": 0.9689683621892562,
"loss_pdi": 0.9294195175170898,
"loss_ee": 0.9251096065227802,
"loss_delivery": 0.8660176992416382,
"loss_biodist": 1.0843104399167574,
"loss_toxic": 0.27184163607083833
"loss": 6.5880933318819315,
"loss_size": 1.750367718083518,
"loss_pdi": 1.3177664024489266,
"loss_ee": 1.068630073751722,
"loss_delivery": 0.8820391488926751,
"loss_biodist": 1.0014605011258806,
"loss_toxic": 0.567829430103302
},
{
"loss": 3.8401913826282206,
"loss_size": 0.2623294328267758,
"loss_pdi": 0.6934819909242483,
"loss_ee": 0.8734692564377418,
"loss_delivery": 0.9325725705577776,
"loss_biodist": 0.8828928974958566,
"loss_toxic": 0.1954453088916265
"loss": 4.678432379450117,
"loss_size": 0.3203257258449282,
"loss_pdi": 1.180948099919728,
"loss_ee": 1.0613888587270464,
"loss_delivery": 0.8234607481530735,
"loss_biodist": 0.7979316924299512,
"loss_toxic": 0.49437726182597025
},
{
"loss": 3.3800897414867697,
"loss_size": 0.25510963281759846,
"loss_pdi": 0.6420884224084707,
"loss_ee": 0.8549692860016456,
"loss_delivery": 0.8087867188912171,
"loss_biodist": 0.6538480222225189,
"loss_toxic": 0.1652876244714627
"loss": 4.174277833529881,
"loss_size": 0.4864327609539032,
"loss_pdi": 1.014147652047021,
"loss_ee": 1.0116309651306696,
"loss_delivery": 0.8047538192144462,
"loss_biodist": 0.5864214556557792,
"loss_toxic": 0.2708912321499416
},
{
"loss": 3.126784379665668,
"loss_size": 0.24261613419422737,
"loss_pdi": 0.6058944624203902,
"loss_ee": 0.8256107156093304,
"loss_delivery": 0.7888596923305438,
"loss_biodist": 0.531504328434284,
"loss_toxic": 0.13229898621256536
"loss": 3.4547910520008633,
"loss_size": 0.31596518414361136,
"loss_pdi": 0.9084383249282837,
"loss_ee": 0.9215172486645835,
"loss_delivery": 0.7124462143651077,
"loss_biodist": 0.42033374096666065,
"loss_toxic": 0.17609038363609994
},
{
"loss": 2.8701502359830418,
"loss_size": 0.2547111769135182,
"loss_pdi": 0.5767100866024311,
"loss_ee": 0.7695629459161025,
"loss_delivery": 0.7461442443040701,
"loss_biodist": 0.42365796520159793,
"loss_toxic": 0.0993638989300682
"loss": 3.2108109337942943,
"loss_size": 0.2688417855118002,
"loss_pdi": 0.8587345012596675,
"loss_ee": 0.875971223626818,
"loss_delivery": 0.7385377415588924,
"loss_biodist": 0.3365256999220167,
"loss_toxic": 0.1321999922926937
},
{
"loss": 2.640800641133235,
"loss_size": 0.23404385321415389,
"loss_pdi": 0.569634735584259,
"loss_ee": 0.7578622423685514,
"loss_delivery": 0.6383189450089748,
"loss_biodist": 0.3649272185105544,
"loss_toxic": 0.0760135928598734
"loss": 2.9460756949016025,
"loss_size": 0.2779192647763661,
"loss_pdi": 0.7961623072624207,
"loss_ee": 0.8504888585635594,
"loss_delivery": 0.6400965334448431,
"loss_biodist": 0.2687057022537504,
"loss_toxic": 0.112703027070633
},
{
"loss": 2.5832578127200785,
"loss_size": 0.23187803878233984,
"loss_pdi": 0.5650712022414575,
"loss_ee": 0.7505346032289358,
"loss_delivery": 0.6600469161684697,
"loss_biodist": 0.31232603925925034,
"loss_toxic": 0.06340097868815064
"loss": 2.7530925273895264,
"loss_size": 0.25332520263535635,
"loss_pdi": 0.7469035514763424,
"loss_ee": 0.8471435691629138,
"loss_delivery": 0.5530903546937874,
"loss_biodist": 0.2454697404588972,
"loss_toxic": 0.10716012333120618
},
{
"loss": 2.4268490993059597,
"loss_size": 0.2535917151432771,
"loss_pdi": 0.49883827567100525,
"loss_ee": 0.6963567412816561,
"loss_delivery": 0.6287171774758742,
"loss_biodist": 0.2783840080866447,
"loss_toxic": 0.07096117032835117
"loss": 2.742221474647522,
"loss_size": 0.2413133829832077,
"loss_pdi": 0.6884610418762479,
"loss_ee": 0.8217804133892059,
"loss_delivery": 0.6628774159720966,
"loss_biodist": 0.23072052534137452,
"loss_toxic": 0.09706869375492845
},
{
"loss": 2.260506345675542,
"loss_size": 0.2080249826495464,
"loss_pdi": 0.5252504096581385,
"loss_ee": 0.6650349016372974,
"loss_delivery": 0.5313630184301963,
"loss_biodist": 0.26103301919423616,
"loss_toxic": 0.06980002821924594
"loss": 2.550677682672228,
"loss_size": 0.2765064158343843,
"loss_pdi": 0.6737975222723824,
"loss_ee": 0.7778623870440892,
"loss_delivery": 0.5299507762704577,
"loss_biodist": 0.1921106672712735,
"loss_toxic": 0.10044991970062256
},
{
"loss": 2.2684748631257277,
"loss_size": 0.23266072456653303,
"loss_pdi": 0.5147650150152353,
"loss_ee": 0.6746502197705783,
"loss_delivery": 0.5654611770923321,
"loss_biodist": 0.2386850737608396,
"loss_toxic": 0.04225267691967579
"loss": 2.481816521712712,
"loss_size": 0.23023176033582007,
"loss_pdi": 0.6636314690113068,
"loss_ee": 0.7728129327297211,
"loss_delivery": 0.5704377527747836,
"loss_biodist": 0.1672141200729779,
"loss_toxic": 0.07748848732028689
},
{
"loss": 2.085041247881376,
"loss_size": 0.21298694839844337,
"loss_pdi": 0.478065183529487,
"loss_ee": 0.624563992023468,
"loss_delivery": 0.4895915320286384,
"loss_biodist": 0.24257883085654333,
"loss_toxic": 0.03725476738495322
"loss": 2.360851458140782,
"loss_size": 0.21546032758695738,
"loss_pdi": 0.6131412557193211,
"loss_ee": 0.830133033650262,
"loss_delivery": 0.4567379740016934,
"loss_biodist": 0.17073182123047964,
"loss_toxic": 0.07464704542819943
},
{
"loss": 2.034342252291166,
"loss_size": 0.20522931390083754,
"loss_pdi": 0.49255690895594084,
"loss_ee": 0.6087538760442001,
"loss_delivery": 0.480256066012841,
"loss_biodist": 0.2110953021507997,
"loss_toxic": 0.03645075023031005
"loss": 2.2426107866423473,
"loss_size": 0.19084072799887508,
"loss_pdi": 0.6170341287340436,
"loss_ee": 0.7295470791203635,
"loss_delivery": 0.4835586505276816,
"loss_biodist": 0.1602931246161461,
"loss_toxic": 0.061337063022490056
},
{
"loss": 1.9308108733250544,
"loss_size": 0.17175877896639016,
"loss_pdi": 0.45260854638539827,
"loss_ee": 0.6115030990197108,
"loss_delivery": 0.46177717126332796,
"loss_biodist": 0.17210170110830894,
"loss_toxic": 0.06106155129292837
"loss": 2.2947227358818054,
"loss_size": 0.21879314631223679,
"loss_pdi": 0.6161722391843796,
"loss_ee": 0.762788040297372,
"loss_delivery": 0.45067436354500906,
"loss_biodist": 0.18453349598816463,
"loss_toxic": 0.061761434456067424
},
{
"loss": 1.8926622317387507,
"loss_size": 0.18219156162096903,
"loss_pdi": 0.45498812886384815,
"loss_ee": 0.6137785132114704,
"loss_delivery": 0.442503636273054,
"loss_biodist": 0.1760710489291411,
"loss_toxic": 0.023129337216512516
"loss": 2.3243510808263506,
"loss_size": 0.23437534804855073,
"loss_pdi": 0.594099121434348,
"loss_ee": 0.77819305232593,
"loss_delivery": 0.4997542394059045,
"loss_biodist": 0.1680830376488822,
"loss_toxic": 0.049846263602375984
},
{
"loss": 1.973634958267212,
"loss_size": 0.1851495263668207,
"loss_pdi": 0.44218484254983753,
"loss_ee": 0.5531376554415777,
"loss_delivery": 0.5962466007241836,
"loss_biodist": 0.1732567583139126,
"loss_toxic": 0.023659600159869745
"loss": 2.2657968997955322,
"loss_size": 0.2230603982295309,
"loss_pdi": 0.6490842210394996,
"loss_ee": 0.7079165577888489,
"loss_delivery": 0.4766663594969681,
"loss_biodist": 0.16171239422900335,
"loss_toxic": 0.0473570313770324
},
{
"loss": 1.834187232531034,
"loss_size": 0.1886328814121393,
"loss_pdi": 0.417209030343936,
"loss_ee": 0.6130589017501245,
"loss_delivery": 0.41392402522839034,
"loss_biodist": 0.17852016595693734,
"loss_toxic": 0.022842258698521897
"loss": 2.2227368525096347,
"loss_size": 0.22425250709056854,
"loss_pdi": 0.6083124216113772,
"loss_ee": 0.7293048288140979,
"loss_delivery": 0.4598711388451712,
"loss_biodist": 0.1544684906091009,
"loss_toxic": 0.04652748556275453
},
{
"loss": 1.6386324167251587,
"loss_size": 0.1619069530413701,
"loss_pdi": 0.40920511002723986,
"loss_ee": 0.543202471274596,
"loss_delivery": 0.3477886743270434,
"loss_biodist": 0.15435600338073877,
"loss_toxic": 0.02217323684061949
"loss": 2.1243858337402344,
"loss_size": 0.21263282213892257,
"loss_pdi": 0.573635390826634,
"loss_ee": 0.6900361818926675,
"loss_delivery": 0.4512601649122579,
"loss_biodist": 0.15764176366584642,
"loss_toxic": 0.03917955420911312
},
{
"loss": 1.6642086597589345,
"loss_size": 0.1822590002646813,
"loss_pdi": 0.38968331194840944,
"loss_ee": 0.5327657415316656,
"loss_delivery": 0.38456671570356077,
"loss_biodist": 0.15715198791944063,
"loss_toxic": 0.01778192028331642
"loss": 2.289846863065447,
"loss_size": 0.21625602032457078,
"loss_pdi": 0.596784600189754,
"loss_ee": 0.7933975628444127,
"loss_delivery": 0.4503451883792877,
"loss_biodist": 0.18038264129843032,
"loss_toxic": 0.05268087850085327
},
{
"loss": 1.561285321529095,
"loss_size": 0.1437432708648535,
"loss_pdi": 0.38639354361937595,
"loss_ee": 0.5043096313109765,
"loss_delivery": 0.35284727811813354,
"loss_biodist": 0.15738230026685274,
"loss_toxic": 0.016609296166839507
"loss": 2.1171253493853976,
"loss_size": 0.21727498407874787,
"loss_pdi": 0.5871099403926304,
"loss_ee": 0.6942037897450584,
"loss_delivery": 0.4114475510349231,
"loss_biodist": 0.16847609941448485,
"loss_toxic": 0.038613016584089825
},
{
"loss": 1.5598738010113056,
"loss_size": 0.14988142280624464,
"loss_pdi": 0.41852312133862424,
"loss_ee": 0.5153307456236619,
"loss_delivery": 0.30808181086411845,
"loss_biodist": 0.1537162667283645,
"loss_toxic": 0.014340438235264558
"loss": 2.2243686744144986,
"loss_size": 0.23041224852204323,
"loss_pdi": 0.5950902572699955,
"loss_ee": 0.7303137523787362,
"loss_delivery": 0.4817630084497588,
"loss_biodist": 0.13934307438986643,
"loss_toxic": 0.047446319966443946
},
{
"loss": 1.586504679459792,
"loss_size": 0.1579624334206948,
"loss_pdi": 0.4118466583582071,
"loss_ee": 0.5027729616715357,
"loss_delivery": 0.33311148560964143,
"loss_biodist": 0.16044681118084833,
"loss_toxic": 0.020364307870085422
"loss": 2.142884841987065,
"loss_size": 0.18598268926143646,
"loss_pdi": 0.5736084473984582,
"loss_ee": 0.7191481994731086,
"loss_delivery": 0.4928105877978461,
"loss_biodist": 0.13822122237512044,
"loss_toxic": 0.03311372648126313
},
{
"loss": 1.5559651026358972,
"loss_size": 0.15422992723492476,
"loss_pdi": 0.40416549490048337,
"loss_ee": 0.5043272055112399,
"loss_delivery": 0.34229428607683915,
"loss_biodist": 0.13546629192737433,
"loss_toxic": 0.015481884215170374
},
{
"loss": 1.474733068392827,
"loss_size": 0.1376458337673774,
"loss_pdi": 0.3663271631185825,
"loss_ee": 0.5019905475469736,
"loss_delivery": 0.3069626304965753,
"loss_biodist": 0.1442684789116566,
"loss_toxic": 0.01753841727398909
},
{
"loss": 1.4861183900099535,
"loss_size": 0.15266291739848944,
"loss_pdi": 0.3844867234046643,
"loss_ee": 0.49344547666036165,
"loss_delivery": 0.292184143112256,
"loss_biodist": 0.14641749343046775,
"loss_toxic": 0.016921617932474382
},
{
"loss": 1.512233894604903,
"loss_size": 0.14189060032367706,
"loss_pdi": 0.4098552969785837,
"loss_ee": 0.4653961268755106,
"loss_delivery": 0.29666711619267094,
"loss_biodist": 0.13669535231131774,
"loss_toxic": 0.061729387344362646
},
{
"loss": 1.4599237900513868,
"loss_size": 0.14220070122526243,
"loss_pdi": 0.4150706483767583,
"loss_ee": 0.46269946602674633,
"loss_delivery": 0.2918037512841133,
"loss_biodist": 0.13078988859286675,
"loss_toxic": 0.017359334491909698
},
{
"loss": 1.576150316458482,
"loss_size": 0.1595412979905422,
"loss_pdi": 0.3765770483475465,
"loss_ee": 0.5104989432371579,
"loss_delivery": 0.3169563438456792,
"loss_biodist": 0.16685812347210371,
"loss_toxic": 0.04571856157137798
},
{
"loss": 1.4343401743815496,
"loss_size": 0.13940962203420126,
"loss_pdi": 0.3983347278374892,
"loss_ee": 0.4601492996399219,
"loss_delivery": 0.27466822358278126,
"loss_biodist": 0.1437123933663735,
"loss_toxic": 0.018065906255147778
},
{
"loss": 1.3912398769305303,
"loss_size": 0.12413510250357482,
"loss_pdi": 0.37387907390411085,
"loss_ee": 0.4670978830410884,
"loss_delivery": 0.2875180955116565,
"loss_biodist": 0.1249157666013791,
"loss_toxic": 0.01369395311205433
},
{
"loss": 1.424091059427995,
"loss_size": 0.15850819360751373,
"loss_pdi": 0.3705967183296497,
"loss_ee": 0.4417672294836778,
"loss_delivery": 0.30434694112493443,
"loss_biodist": 0.13330914022830817,
"loss_toxic": 0.015562845026859297
},
{
"loss": 1.40188762316337,
"loss_size": 0.13292228774382517,
"loss_pdi": 0.3610769865604547,
"loss_ee": 0.5077145374738253,
"loss_delivery": 0.2582832815555426,
"loss_biodist": 0.12532487941476014,
"loss_toxic": 0.0165656553223156
},
{
"loss": 1.3533825324131892,
"loss_size": 0.13495178577991632,
"loss_pdi": 0.3524953780265955,
"loss_ee": 0.4514327874550453,
"loss_delivery": 0.25540869382138437,
"loss_biodist": 0.13806180197459,
"loss_toxic": 0.021032094086806934
},
{
"loss": 1.3358305784372182,
"loss_size": 0.14862898737192154,
"loss_pdi": 0.3689935069817763,
"loss_ee": 0.4314877482560965,
"loss_delivery": 0.24364815193873185,
"loss_biodist": 0.13041460055571336,
"loss_toxic": 0.01265757203173752
"loss": 2.0640590446335927,
"loss_size": 0.1981512185718332,
"loss_pdi": 0.5239957081420081,
"loss_ee": 0.6807411738804409,
"loss_delivery": 0.45748772472143173,
"loss_biodist": 0.14945154903190477,
"loss_toxic": 0.0542316823931677
}
],
"val": [
{
"loss": 9.567692279815674,
"loss_size": 4.553072690963745,
"loss_pdi": 1.0625805258750916,
"loss_ee": 0.9942680895328522,
"loss_delivery": 1.47209894657135,
"loss_biodist": 1.1432022452354431,
"loss_toxic": 0.3424694389104843,
"acc_pdi": 0.75,
"acc_ee": 0.5909090909090909,
"acc_toxic": 1.0
},
{
"loss": 4.354300379753113,
"loss_size": 0.20095597207546234,
"loss_pdi": 0.7770168483257294,
"loss_ee": 0.9953322410583496,
"loss_delivery": 1.3067785501480103,
"loss_biodist": 0.9856867492198944,
"loss_toxic": 0.08853016048669815,
"acc_pdi": 0.75,
"acc_ee": 0.5909090909090909,
"acc_toxic": 1.0
},
{
"loss": 4.091485023498535,
"loss_size": 0.1840391382575035,
"loss_pdi": 0.6579808592796326,
"loss_ee": 0.9572223722934723,
"loss_delivery": 1.386644184589386,
"loss_biodist": 0.8630380034446716,
"loss_toxic": 0.04256031848490238,
"acc_pdi": 0.75,
"acc_ee": 0.5909090909090909,
"acc_toxic": 1.0
},
{
"loss": 3.5865455865859985,
"loss_size": 0.16276441887021065,
"loss_pdi": 0.6156152784824371,
"loss_ee": 0.8769127726554871,
"loss_delivery": 1.185390830039978,
"loss_biodist": 0.693861186504364,
"loss_toxic": 0.05200100876390934,
"acc_pdi": 0.75,
"acc_ee": 0.5909090909090909,
"acc_toxic": 1.0
},
{
"loss": 3.216905355453491,
"loss_size": 0.20165041834115982,
"loss_pdi": 0.6010490655899048,
"loss_ee": 0.8362293839454651,
"loss_delivery": 1.0108550190925598,
"loss_biodist": 0.4944496750831604,
"loss_toxic": 0.0726719107478857,
"acc_pdi": 0.75,
"acc_ee": 0.6363636363636364,
"acc_toxic": 1.0
},
{
"loss": 3.0632435083389282,
"loss_size": 0.24732542037963867,
"loss_pdi": 0.5763635039329529,
"loss_ee": 0.8021132349967957,
"loss_delivery": 0.8960984945297241,
"loss_biodist": 0.4863189309835434,
"loss_toxic": 0.05502396076917648,
"acc_pdi": 0.75,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.8909536600112915,
"loss_size": 0.19840088486671448,
"loss_pdi": 0.5675790905952454,
"loss_ee": 0.789268285036087,
"loss_delivery": 0.8245587646961212,
"loss_biodist": 0.45656538009643555,
"loss_toxic": 0.054581284523010254,
"acc_pdi": 0.7272727272727273,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.771771550178528,
"loss_size": 0.1412012092769146,
"loss_pdi": 0.5785803645849228,
"loss_ee": 0.7794539630413055,
"loss_delivery": 0.7300527393817902,
"loss_biodist": 0.4118006229400635,
"loss_toxic": 0.130682535469532,
"acc_pdi": 0.7272727272727273,
"acc_ee": 0.6363636363636364,
"acc_toxic": 0.9090909090909091
},
{
"loss": 2.692520260810852,
"loss_size": 0.1475178860127926,
"loss_pdi": 0.5785025954246521,
"loss_ee": 0.7986349761486053,
"loss_delivery": 0.6745082139968872,
"loss_biodist": 0.3999589830636978,
"loss_toxic": 0.09339761920273304,
"acc_pdi": 0.7272727272727273,
"acc_ee": 0.5454545454545454,
"acc_toxic": 1.0
},
{
"loss": 2.8346426486968994,
"loss_size": 0.1516040787100792,
"loss_pdi": 0.5753654837608337,
"loss_ee": 0.8160740733146667,
"loss_delivery": 0.7168894708156586,
"loss_biodist": 0.47982172667980194,
"loss_toxic": 0.09488803520798683,
"acc_pdi": 0.75,
"acc_ee": 0.6818181818181818,
"acc_toxic": 1.0
},
{
"loss": 2.7991228103637695,
"loss_size": 0.13234595209360123,
"loss_pdi": 0.5597751885652542,
"loss_ee": 0.8118472993373871,
"loss_delivery": 0.8289965093135834,
"loss_biodist": 0.3804939240217209,
"loss_toxic": 0.0856639239937067,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6136363636363636,
"acc_toxic": 1.0
},
{
"loss": 2.5899158716201782,
"loss_size": 0.10683015361428261,
"loss_pdi": 0.5460522472858429,
"loss_ee": 0.8205565512180328,
"loss_delivery": 0.5881542563438416,
"loss_biodist": 0.47443418204784393,
"loss_toxic": 0.053888481110334396,
"acc_pdi": 0.7954545454545454,
"acc_ee": 0.6818181818181818,
"acc_toxic": 1.0
},
{
"loss": 2.725231647491455,
"loss_size": 0.11643071845173836,
"loss_pdi": 0.5444842875003815,
"loss_ee": 0.8331143856048584,
"loss_delivery": 0.7808746695518494,
"loss_biodist": 0.3872501105070114,
"loss_toxic": 0.06307746656239033,
"acc_pdi": 0.8181818181818182,
"acc_ee": 0.6818181818181818,
"acc_toxic": 1.0
},
{
"loss": 2.6474616527557373,
"loss_size": 0.10570626705884933,
"loss_pdi": 0.5306982547044754,
"loss_ee": 0.8475350737571716,
"loss_delivery": 0.6773415505886078,
"loss_biodist": 0.45252545177936554,
"loss_toxic": 0.033654999919235706,
"acc_pdi": 0.7954545454545454,
"acc_ee": 0.7045454545454546,
"acc_toxic": 1.0
},
{
"loss": 2.7429730892181396,
"loss_size": 0.13143501430749893,
"loss_pdi": 0.5128554701805115,
"loss_ee": 0.8301066756248474,
"loss_delivery": 0.7826772928237915,
"loss_biodist": 0.4481300711631775,
"loss_toxic": 0.03776852134615183,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.7127978801727295,
"loss_size": 0.19175250455737114,
"loss_pdi": 0.516972616314888,
"loss_ee": 0.8794091939926147,
"loss_delivery": 0.6612942218780518,
"loss_biodist": 0.4495534151792526,
"loss_toxic": 0.01381598599255085,
"acc_pdi": 0.7954545454545454,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.605361819267273,
"loss_size": 0.0976286269724369,
"loss_pdi": 0.5153753459453583,
"loss_ee": 0.8854215145111084,
"loss_delivery": 0.6795051693916321,
"loss_biodist": 0.3929741233587265,
"loss_toxic": 0.0344569431617856,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6136363636363636,
"acc_toxic": 1.0
},
{
"loss": 2.6061036586761475,
"loss_size": 0.13404572382569313,
"loss_pdi": 0.5658221244812012,
"loss_ee": 0.8649452030658722,
"loss_delivery": 0.5898179858922958,
"loss_biodist": 0.4181220978498459,
"loss_toxic": 0.03335061576217413,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6363636363636364,
"acc_toxic": 1.0
},
{
"loss": 2.566210627555847,
"loss_size": 0.09801355004310608,
"loss_pdi": 0.5331112891435623,
"loss_ee": 0.8543781340122223,
"loss_delivery": 0.663883626461029,
"loss_biodist": 0.40053851902484894,
"loss_toxic": 0.01628561830148101,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6363636363636364,
"acc_toxic": 1.0
},
{
"loss": 2.5774325132369995,
"loss_size": 0.10316971689462662,
"loss_pdi": 0.5015804171562195,
"loss_ee": 0.8556492626667023,
"loss_delivery": 0.6874183714389801,
"loss_biodist": 0.40917880833148956,
"loss_toxic": 0.02043590322136879,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6818181818181818,
"acc_toxic": 1.0
},
{
"loss": 2.605422019958496,
"loss_size": 0.09912058711051941,
"loss_pdi": 0.5235853344202042,
"loss_ee": 0.873578816652298,
"loss_delivery": 0.6754274368286133,
"loss_biodist": 0.41106243431568146,
"loss_toxic": 0.022647667676210403,
"acc_pdi": 0.75,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6543829441070557,
"loss_size": 0.09768814221024513,
"loss_pdi": 0.49928364157676697,
"loss_ee": 0.887874037027359,
"loss_delivery": 0.7190346419811249,
"loss_biodist": 0.3921310156583786,
"loss_toxic": 0.0583715345710516,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6818181818181818,
"acc_toxic": 0.9696969696969697
},
{
"loss": 2.567589282989502,
"loss_size": 0.09272187761962414,
"loss_pdi": 0.51718769967556,
"loss_ee": 0.9185941517353058,
"loss_delivery": 0.6525538563728333,
"loss_biodist": 0.37214455008506775,
"loss_toxic": 0.014387213159352541,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.5968352556228638,
"loss_size": 0.08045755326747894,
"loss_pdi": 0.5356858968734741,
"loss_ee": 0.9407581686973572,
"loss_delivery": 0.634858101606369,
"loss_biodist": 0.3985549360513687,
"loss_toxic": 0.006520765833556652,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6400684118270874,
"loss_size": 0.10199694335460663,
"loss_pdi": 0.517327144742012,
"loss_ee": 0.9348995685577393,
"loss_delivery": 0.6469141840934753,
"loss_biodist": 0.4060143977403641,
"loss_toxic": 0.032916306518018246,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6818181818181818,
"acc_toxic": 1.0
},
{
"loss": 2.684706211090088,
"loss_size": 0.08828861452639103,
"loss_pdi": 0.5358051210641861,
"loss_ee": 0.9240424036979675,
"loss_delivery": 0.7182384729385376,
"loss_biodist": 0.4059095233678818,
"loss_toxic": 0.012422125786542892,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.665715456008911,
"loss_size": 0.09193641319870949,
"loss_pdi": 0.5586960315704346,
"loss_ee": 0.9341873526573181,
"loss_delivery": 0.6672921180725098,
"loss_biodist": 0.39184093475341797,
"loss_toxic": 0.021762709133327007,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.596559524536133,
"loss_size": 0.09265327453613281,
"loss_pdi": 0.528680682182312,
"loss_ee": 0.919374018907547,
"loss_delivery": 0.6490764021873474,
"loss_biodist": 0.3949074149131775,
"loss_toxic": 0.011867486871778965,
"acc_pdi": 0.75,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.585421562194824,
"loss_size": 0.0936437975615263,
"loss_pdi": 0.5345576107501984,
"loss_ee": 0.9352433085441589,
"loss_delivery": 0.6098059117794037,
"loss_biodist": 0.3938410133123398,
"loss_toxic": 0.018329923041164875,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.655733346939087,
"loss_size": 0.10606781952083111,
"loss_pdi": 0.5337405353784561,
"loss_ee": 0.9154745638370514,
"loss_delivery": 0.7101629674434662,
"loss_biodist": 0.38175711035728455,
"loss_toxic": 0.00853043282404542,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6239495277404785,
"loss_size": 0.0914073996245861,
"loss_pdi": 0.5375382900238037,
"loss_ee": 0.9078292548656464,
"loss_delivery": 0.693512886762619,
"loss_biodist": 0.3826553374528885,
"loss_toxic": 0.011006365530192852,
"acc_pdi": 0.8181818181818182,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6274508237838745,
"loss_size": 0.0975069236010313,
"loss_pdi": 0.5298525840044022,
"loss_ee": 0.9227176904678345,
"loss_delivery": 0.6834201812744141,
"loss_biodist": 0.3833360821008682,
"loss_toxic": 0.010617360007017851,
"acc_pdi": 0.7954545454545454,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6211040019989014,
"loss_size": 0.108822550624609,
"loss_pdi": 0.5202214568853378,
"loss_ee": 0.9265661537647247,
"loss_delivery": 0.6657091081142426,
"loss_biodist": 0.39240916073322296,
"loss_toxic": 0.007375639397650957,
"acc_pdi": 0.75,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
},
{
"loss": 2.6309741735458374,
"loss_size": 0.10216855630278587,
"loss_pdi": 0.5254682153463364,
"loss_ee": 0.9219010472297668,
"loss_delivery": 0.6798527538776398,
"loss_biodist": 0.3923489600419998,
"loss_toxic": 0.009234576486051083,
"acc_pdi": 0.7727272727272727,
"acc_ee": 0.6590909090909091,
"acc_toxic": 1.0
}
]
"val": []
}

BIN
models/final/loss_curves.png
View File

Binary file not shown.
Side by Side Swipe Overlay

Before

Width:  |  Height:  |  Size: 260 KiB

After

Width:  |  Height:  |  Size: 212 KiB

4
models/final/model.pt
View File

@ -1,3 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:cf4f2329b476c1e361fa04ed2a27b832346bdf3b92f71830049cd41698bbd7bb
size 28581662
oid sha256:241b22c5170dd7d5a82f409228589d61d16ca14c3ae1991a03bda8ca547ce743
size 28583340

BIN
models/final/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

962
models/final/optuna_trials.json Normal file
View File

@ -0,0 +1,962 @@
[
{
"number": 0,
"value": 2.8156970342000327,
"params": {
"dropout": 0.249816047538945,
"lr": 0.0007969454818643932,
"weight_decay": 0.008471801418819975,
"backbone_lr_ratio": 0.15751320499779725
},
"user_attrs": {
"epoch_mean": 14,
"fold_best_epochs": [
10,
12,
21
],
"fold_val_losses": [
3.733495855331421,
2.5024956703186034,
2.2110995769500734
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 1,
"value": 3.3739805857340492,
"params": {
"dropout": 0.1624074561769746,
"lr": 2.0511104188433963e-05,
"weight_decay": 1.7073967431528103e-05,
"backbone_lr_ratio": 0.5399484409787431
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
3.7005380153656007,
3.236070442199707,
3.1853332996368406
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 2,
"value": 2.6023060957590736,
"params": {
"dropout": 0.34044600469728353,
"lr": 0.0002607024758370766,
"weight_decay": 1.2087541473056957e-05,
"backbone_lr_ratio": 0.8706020878304853
},
"user_attrs": {
"epoch_mean": 16,
"fold_best_epochs": [
14,
19,
16
],
"fold_val_losses": [
3.283898639678955,
2.366805338859558,
2.1562143087387087
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 3,
"value": 10.838356399536133,
"params": {
"dropout": 0.4329770563201687,
"lr": 2.6587543983272695e-05,
"weight_decay": 5.3370327626039544e-05,
"backbone_lr_ratio": 0.023270677083837805
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
9.760257911682128,
10.611498069763183,
12.143313217163087
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 4,
"value": 3.0307216803232833,
"params": {
"dropout": 0.2216968971838151,
"lr": 0.00011207606211860574,
"weight_decay": 0.0005342937261279777,
"backbone_lr_ratio": 0.038234752246751866
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
29,
30,
30
],
"fold_val_losses": [
3.6398903369903564,
2.7796840190887453,
2.6725906848907472
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 5,
"value": 12.962510363260904,
"params": {
"dropout": 0.34474115788895177,
"lr": 1.9010245319870364e-05,
"weight_decay": 0.00014742753159914678,
"backbone_lr_ratio": 0.05404103854647329
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
11.658656311035156,
13.798492240905762,
13.430382537841798
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 6,
"value": 2.8127863725026447,
"params": {
"dropout": 0.28242799368681437,
"lr": 0.00037183641805732076,
"weight_decay": 6.290644294586152e-05,
"backbone_lr_ratio": 0.10677482709481352
},
"user_attrs": {
"epoch_mean": 21,
"fold_best_epochs": [
15,
20,
28
],
"fold_val_losses": [
3.527592992782593,
2.6037728786468506,
2.306993246078491
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 7,
"value": 18.49700838724772,
"params": {
"dropout": 0.33696582754481696,
"lr": 1.2385137298860926e-05,
"weight_decay": 0.0026926469100861782,
"backbone_lr_ratio": 0.021930485556643693
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
18.425870513916017,
18.542006301879884,
18.523148345947266
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 8,
"value": 2.6576756556828816,
"params": {
"dropout": 0.12602063719411183,
"lr": 0.000790261954970823,
"weight_decay": 0.07286653737491042,
"backbone_lr_ratio": 0.4138040112561014
},
"user_attrs": {
"epoch_mean": 10,
"fold_best_epochs": [
9,
11,
10
],
"fold_val_losses": [
3.56644024848938,
2.2665807485580443,
2.1400059700012206
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 9,
"value": 11.92358964284261,
"params": {
"dropout": 0.2218455076693483,
"lr": 1.5679933916722995e-05,
"weight_decay": 0.005456725485601475,
"backbone_lr_ratio": 0.07591104805282695
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
12.178006362915038,
12.020879745483398,
11.571882820129394
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 10,
"value": 2.744228076934814,
"params": {
"dropout": 0.48159581757804304,
"lr": 0.00013112992007873722,
"weight_decay": 1.0719864040714885e-05,
"backbone_lr_ratio": 0.8131735182005935
},
"user_attrs": {
"epoch_mean": 25,
"fold_best_epochs": [
21,
29,
24
],
"fold_val_losses": [
3.2794203758239746,
2.4811975240707396,
2.472066330909729
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 11,
"value": 2.600485173861186,
"params": {
"dropout": 0.1398149921035961,
"lr": 0.0003676766469931975,
"weight_decay": 0.0814481577934799,
"backbone_lr_ratio": 0.416600060135216
},
"user_attrs": {
"epoch_mean": 14,
"fold_best_epochs": [
8,
14,
21
],
"fold_val_losses": [
3.2930724143981935,
2.312326765060425,
2.196056342124939
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 12,
"value": 2.856875479221344,
"params": {
"dropout": 0.39786435978029433,
"lr": 0.00027104165213579705,
"weight_decay": 0.09324179801968951,
"backbone_lr_ratio": 0.24792013326598586
},
"user_attrs": {
"epoch_mean": 17,
"fold_best_epochs": [
14,
12,
25
],
"fold_val_losses": [
3.5214386940002442,
2.671292519569397,
2.3778952240943907
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 13,
"value": 2.5929951747258504,
"params": {
"dropout": 0.1708198460450869,
"lr": 0.0002771027430797957,
"weight_decay": 0.022371906875975713,
"backbone_lr_ratio": 0.8529032090320552
},
"user_attrs": {
"epoch_mean": 11,
"fold_best_epochs": [
9,
12,
13
],
"fold_val_losses": [
3.211256170272827,
2.29467031955719,
2.273059034347534
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 14,
"value": 2.7000243584314982,
"params": {
"dropout": 0.10319674017011438,
"lr": 5.318587054778435e-05,
"weight_decay": 0.026386070022612545,
"backbone_lr_ratio": 0.3335324680299515
},
"user_attrs": {
"epoch_mean": 28,
"fold_best_epochs": [
26,
29,
30
],
"fold_val_losses": [
3.095314884185791,
2.559102272987366,
2.445655918121338
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 15,
"value": 2.811073144276937,
"params": {
"dropout": 0.17491537723907288,
"lr": 0.0004715550190685932,
"weight_decay": 0.020503728356529433,
"backbone_lr_ratio": 0.202005130829578
},
"user_attrs": {
"epoch_mean": 15,
"fold_best_epochs": [
11,
13,
22
],
"fold_val_losses": [
3.665318727493286,
2.5160216808319094,
2.251879024505615
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 16,
"value": 2.51602889696757,
"params": {
"dropout": 0.157877413230548,
"lr": 0.00016221844139316182,
"weight_decay": 0.0011695139073230128,
"backbone_lr_ratio": 0.9818226878189111
},
"user_attrs": {
"epoch_mean": 19,
"fold_best_epochs": [
12,
21,
24
],
"fold_val_losses": [
2.967289590835571,
2.41019024848938,
2.170606851577759
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 17,
"value": 2.617725872993469,
"params": {
"dropout": 0.1975499843454273,
"lr": 6.0680145665816345e-05,
"weight_decay": 0.0006054421043842105,
"backbone_lr_ratio": 0.9370662382902515
},
"user_attrs": {
"epoch_mean": 28,
"fold_best_epochs": [
23,
30,
30
],
"fold_val_losses": [
3.112912178039551,
2.4265938997268677,
2.3136715412139894
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 18,
"value": 2.6030575354894006,
"params": {
"dropout": 0.2840632229983807,
"lr": 0.00016641263642332344,
"weight_decay": 0.0015861751549934148,
"backbone_lr_ratio": 0.5813736146009224
},
"user_attrs": {
"epoch_mean": 23,
"fold_best_epochs": [
21,
21,
27
],
"fold_val_losses": [
3.163059639930725,
2.3479116916656495,
2.2982012748718263
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 19,
"value": 2.865672874450684,
"params": {
"dropout": 0.10525612628712336,
"lr": 6.627976747186786e-05,
"weight_decay": 0.00020126720225868128,
"backbone_lr_ratio": 0.12579626206936234
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
3.413493585586548,
2.58580904006958,
2.5977159976959228
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 20,
"value": 2.541643071174622,
"params": {
"dropout": 0.24563678706364706,
"lr": 0.0002197507105689095,
"weight_decay": 0.01585496331337175,
"backbone_lr_ratio": 0.2693624761288439
},
"user_attrs": {
"epoch_mean": 19,
"fold_best_epochs": [
15,
18,
24
],
"fold_val_losses": [
3.2464155673980715,
2.2392319440841675,
2.139281702041626
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 21,
"value": 2.5363871733347576,
"params": {
"dropout": 0.24822650356184767,
"lr": 0.00018488380020633278,
"weight_decay": 0.016124874730349143,
"backbone_lr_ratio": 0.30071816195793755
},
"user_attrs": {
"epoch_mean": 21,
"fold_best_epochs": [
13,
26,
24
],
"fold_val_losses": [
3.1824454784393312,
2.337935042381287,
2.088780999183655
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 22,
"value": 2.608898858229319,
"params": {
"dropout": 0.23999254948655954,
"lr": 0.00019074146892949267,
"weight_decay": 0.007473456802129268,
"backbone_lr_ratio": 0.24792013326598586
},
"user_attrs": {
"epoch_mean": 18,
"fold_best_epochs": [
12,
18,
25
],
"fold_val_losses": [
3.299156427383423,
2.3785044670104982,
2.1490356802940367
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 23,
"value": 2.6372965017954506,
"params": {
"dropout": 0.2732819324439319,
"lr": 8.559450244862353e-05,
"weight_decay": 0.003126023459511234,
"backbone_lr_ratio": 0.3168235172426432
},
"user_attrs": {
"epoch_mean": 27,
"fold_best_epochs": [
28,
22,
30
],
"fold_val_losses": [
3.0834681034088134,
2.466027092933655,
2.3623943090438844
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 24,
"value": 2.482991655667623,
"params": {
"dropout": 0.30169410062526664,
"lr": 0.000178917590650789,
"weight_decay": 0.013098468879191921,
"backbone_lr_ratio": 0.5322698244647086
},
"user_attrs": {
"epoch_mean": 19,
"fold_best_epochs": [
18,
16,
23
],
"fold_val_losses": [
2.952860403060913,
2.3297120332717896,
2.166402530670166
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 25,
"value": 2.767317620913188,
"params": {
"dropout": 0.3194613602400577,
"lr": 4.342839523653342e-05,
"weight_decay": 0.001138022773453874,
"backbone_lr_ratio": 0.575108040368093
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
29
],
"fold_val_losses": [
3.0871256828308105,
2.6297523975372314,
2.585074782371521
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 26,
"value": 2.6014270941416426,
"params": {
"dropout": 0.380465038157504,
"lr": 0.000131818792969444,
"weight_decay": 0.031283173085439854,
"backbone_lr_ratio": 0.5275684824553009
},
"user_attrs": {
"epoch_mean": 23,
"fold_best_epochs": [
21,
25,
24
],
"fold_val_losses": [
3.164607048034668,
2.430464816093445,
2.209209418296814
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 27,
"value": 2.627247397104899,
"params": {
"dropout": 0.20197960767997714,
"lr": 8.186282230228678e-05,
"weight_decay": 0.003540606605897514,
"backbone_lr_ratio": 0.17090703553802636
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
29,
30,
30
],
"fold_val_losses": [
3.2599289894104,
2.3099464178085327,
2.311866784095764
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 28,
"value": 2.6080079317092895,
"params": {
"dropout": 0.29875866523156275,
"lr": 0.0004703885391544067,
"weight_decay": 0.045327015648549004,
"backbone_lr_ratio": 0.6534099986720939
},
"user_attrs": {
"epoch_mean": 15,
"fold_best_epochs": [
9,
12,
25
],
"fold_val_losses": [
3.350850296020508,
2.2914549112319946,
2.181718587875366
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 29,
"value": 2.6760944962501525,
"params": {
"dropout": 0.26572299607512456,
"lr": 0.0007379244149640388,
"weight_decay": 0.008589710887330617,
"backbone_lr_ratio": 0.40188133372791734
},
"user_attrs": {
"epoch_mean": 13,
"fold_best_epochs": [
9,
13,
17
],
"fold_val_losses": [
3.524716091156006,
2.295975375175476,
2.207592022418976
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 30,
"value": 3.544327608744304,
"params": {
"dropout": 0.3647346234383415,
"lr": 3.7911482246002866e-05,
"weight_decay": 0.011264417139383486,
"backbone_lr_ratio": 0.18158532922746584
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
30
],
"fold_val_losses": [
3.795345687866211,
3.331618309020996,
3.5060188293457033
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 31,
"value": 2.553473687171936,
"params": {
"dropout": 0.24271079071613583,
"lr": 0.0002079970663621355,
"weight_decay": 0.01383692673296454,
"backbone_lr_ratio": 0.2928581085972686
},
"user_attrs": {
"epoch_mean": 20,
"fold_best_epochs": [
14,
19,
28
],
"fold_val_losses": [
3.171020269393921,
2.3204617738723754,
2.1689390182495116
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 32,
"value": 2.7147754907608026,
"params": {
"dropout": 0.3081417266050286,
"lr": 0.00015961988076370855,
"weight_decay": 0.005647416385662339,
"backbone_lr_ratio": 0.13126369611144165
},
"user_attrs": {
"epoch_mean": 25,
"fold_best_epochs": [
19,
28,
28
],
"fold_val_losses": [
3.3805705070495606,
2.4436901807785034,
2.3200657844543455
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 33,
"value": 2.8405439217885338,
"params": {
"dropout": 0.19697712607188347,
"lr": 0.00022483991847689944,
"weight_decay": 0.04396257638256477,
"backbone_lr_ratio": 0.01101100938924494
},
"user_attrs": {
"epoch_mean": 26,
"fold_best_epochs": [
19,
30,
30
],
"fold_val_losses": [
3.8356207847595214,
2.3643120765686034,
2.3216989040374756
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 34,
"value": 2.503487364451091,
"params": {
"dropout": 0.2561341328718051,
"lr": 0.00010300416486373038,
"weight_decay": 0.012808904827686988,
"backbone_lr_ratio": 0.6727535050162337
},
"user_attrs": {
"epoch_mean": 24,
"fold_best_epochs": [
17,
27,
28
],
"fold_val_losses": [
3.041924476623535,
2.3080700874328612,
2.160467529296875
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 35,
"value": 2.4608302156130475,
"params": {
"dropout": 0.15463920314801388,
"lr": 0.00011604934996458467,
"weight_decay": 0.001746884129583056,
"backbone_lr_ratio": 0.7073818888939638
},
"user_attrs": {
"epoch_mean": 18,
"fold_best_epochs": [
16,
16,
23
],
"fold_val_losses": [
2.9413320541381838,
2.2545334100723267,
2.1866251826286316
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 36,
"value": 2.452152466773987,
"params": {
"dropout": 0.14731648771233646,
"lr": 0.00010399668603456206,
"weight_decay": 0.0007696017715340258,
"backbone_lr_ratio": 0.7472270478607838
},
"user_attrs": {
"epoch_mean": 23,
"fold_best_epochs": [
19,
21,
29
],
"fold_val_losses": [
2.921252131462097,
2.245358777046204,
2.1898464918136598
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 37,
"value": 2.5273226141929626,
"params": {
"dropout": 0.14194609604277394,
"lr": 0.00010021053483316553,
"weight_decay": 0.00038614379642781024,
"backbone_lr_ratio": 0.7094861329105961
},
"user_attrs": {
"epoch_mean": 21,
"fold_best_epochs": [
17,
19,
28
],
"fold_val_losses": [
3.076446294784546,
2.3063220262527464,
2.1991995215415954
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 38,
"value": 2.8850494384765626,
"params": {
"dropout": 0.2174541133163097,
"lr": 3.3739662416512915e-05,
"weight_decay": 0.002017506096408397,
"backbone_lr_ratio": 0.4899201254858191
},
"user_attrs": {
"epoch_mean": 30,
"fold_best_epochs": [
30,
30,
29
],
"fold_val_losses": [
3.2505751609802247,
2.640340280532837,
2.764232873916626
]
},
"state": "TrialState.COMPLETE"
},
{
"number": 39,
"value": 2.597004270553589,
"params": {
"dropout": 0.4276269504938004,
"lr": 0.0001196820298534061,
"weight_decay": 0.00035992145065850994,
"backbone_lr_ratio": 0.7607765936389007
},
"user_attrs": {
"epoch_mean": 25,
"fold_best_epochs": [
24,
24,
27
],
"fold_val_losses": [
3.053041934967041,
2.4371867895126345,
2.3007840871810914
]
},
"state": "TrialState.COMPLETE"
}
]

60
models/final/strata_info.json Normal file
View File

@ -0,0 +1,60 @@
{
"original_strata_counts": {
"T0|P0|E0": "5",
"T0|P0|E1": "58",
"T0|P0|E2": "169",
"T0|P1|E0": "1",
"T0|P1|E1": "17",
"T0|P1|E2": "32",
"T0|P2|E2": "3",
"T1|P0|E2": "9",
"T1|P1|E2": "5",
"TNA|P0|E0": "28",
"TNA|P0|E1": "21",
"TNA|P0|E2": "20",
"TNA|P1|E0": "29",
"TNA|P1|E1": "7",
"TNA|P1|E2": "14",
"TNA|P2|E2": "1",
"TNA|P3|E0": "1"
},
"rare_strata": [
"T0|P1|E0",
"T0|P2|E2",
"TNA|P2|E2",
"TNA|P3|E0"
],
"final_strata": [
"RARE",
"T0|P0|E0",
"T0|P0|E1",
"T0|P0|E2",
"T0|P1|E1",
"T0|P1|E2",
"T1|P0|E2",
"T1|P1|E2",
"TNA|P0|E0",
"TNA|P0|E1",
"TNA|P0|E2",
"TNA|P1|E0",
"TNA|P1|E1",
"TNA|P1|E2"
],
"final_strata_counts": {
"RARE": "6",
"T0|P0|E0": "5",
"T0|P0|E1": "58",
"T0|P0|E2": "169",
"T0|P1|E1": "17",
"T0|P1|E2": "32",
"T1|P0|E2": "9",
"T1|P1|E2": "5",
"TNA|P0|E0": "28",
"TNA|P0|E1": "21",
"TNA|P0|E2": "20",
"TNA|P1|E0": "29",
"TNA|P1|E1": "7",
"TNA|P1|E2": "14"
},
"n_rare_merged": "6"
}

16
models/finetune_cv/config.json
View File

@ -1,16 +0,0 @@
{
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 32,
"epochs": 100,
"patience": 15,
"init_from_pretrain": "models/pretrain_delivery.pt",
"freeze_backbone": false
}

54
models/finetune_cv/cv_results.json
View File

@ -1,54 +0,0 @@
{
"fold_results": [
{
"fold_idx": 0,
"best_val_loss": 0.9860520362854004,
"epochs_trained": 40,
"final_train_loss": 0.5008097920152876
},
{
"fold_idx": 1,
"best_val_loss": 2.4599782625834146,
"epochs_trained": 38,
"final_train_loss": 0.564177993271086
},
{
"fold_idx": 2,
"best_val_loss": 0.7660132050514221,
"epochs_trained": 43,
"final_train_loss": 0.6722757054699792
},
{
"fold_idx": 3,
"best_val_loss": 1.065057098865509,
"epochs_trained": 31,
"final_train_loss": 0.7323974437183804
},
{
"fold_idx": 4,
"best_val_loss": 1.321769932905833,
"epochs_trained": 36,
"final_train_loss": 0.5991987817817264
}
],
"summary": {
"val_loss_mean": 1.3197741071383158,
"val_loss_std": 0.5971552245392587
},
"config": {
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 32,
"epochs": 100,
"patience": 15,
"init_from_pretrain": "models/pretrain_delivery.pt",
"freeze_backbone": false
}
}

846
models/finetune_cv/fold_0/history.json
View File

@ -1,846 +0,0 @@
{
"train": [
{
"loss": 4.322104136149089,
"loss_size": 17.593045446607803,
"loss_pdi": 1.3204891549216375,
"loss_ee": 1.088417410850525,
"loss_delivery": 0.633530682987637,
"loss_biodist": 1.173327750629849,
"loss_toxic": 0.6653845177756416
},
{
"loss": 3.0454922252231174,
"loss_size": 10.560075124104818,
"loss_pdi": 1.0834629535675049,
"loss_ee": 1.0191341439882915,
"loss_delivery": 0.44744866920842064,
"loss_biodist": 0.8864452905125089,
"loss_toxic": 0.49623291360007393
},
{
"loss": 2.1133340994517007,
"loss_size": 4.667804373635186,
"loss_pdi": 0.8770387834972806,
"loss_ee": 0.9207223057746887,
"loss_delivery": 0.3867781667245759,
"loss_biodist": 0.7044006784756979,
"loss_toxic": 0.32092855042881435
},
{
"loss": 1.6157594124476116,
"loss_size": 1.6370841993225946,
"loss_pdi": 0.7222660581270853,
"loss_ee": 0.9178307851155599,
"loss_delivery": 0.3380226459768083,
"loss_biodist": 0.6118268834220039,
"loss_toxic": 0.2034479926029841
},
{
"loss": 1.6780848105748494,
"loss_size": 0.6989439659648471,
"loss_pdi": 0.6804316308763292,
"loss_ee": 0.8478401038381789,
"loss_delivery": 0.5942584524552027,
"loss_biodist": 0.5482071174515618,
"loss_toxic": 0.14486626535654068
},
{
"loss": 1.464562992254893,
"loss_size": 0.5176780256960127,
"loss_pdi": 0.625754091474745,
"loss_ee": 0.8957585692405701,
"loss_delivery": 0.47431792318820953,
"loss_biodist": 0.47612329986360336,
"loss_toxic": 0.11800290064679252
},
{
"loss": 1.1244084239006042,
"loss_size": 0.4179711126618915,
"loss_pdi": 0.570526036951277,
"loss_ee": 0.8536430464850532,
"loss_delivery": 0.312320727441046,
"loss_biodist": 0.338322220577134,
"loss_toxic": 0.0943529676232073
},
{
"loss": 1.0499339832199945,
"loss_size": 0.47809311416414046,
"loss_pdi": 0.557487385140525,
"loss_ee": 0.8040152788162231,
"loss_delivery": 0.2682522022061878,
"loss_biodist": 0.320782999197642,
"loss_toxic": 0.09277316265636021
},
{
"loss": 1.1732424232694838,
"loss_size": 0.291741915875011,
"loss_pdi": 0.5256910257869296,
"loss_ee": 0.7830515106519064,
"loss_delivery": 0.4160807066493564,
"loss_biodist": 0.3308183021015591,
"loss_toxic": 0.09092888898319668
},
{
"loss": 0.9304312202665541,
"loss_size": 0.34245120154486763,
"loss_pdi": 0.5300001137786441,
"loss_ee": 0.8330901198916965,
"loss_delivery": 0.23890193717347252,
"loss_biodist": 0.24359119104014504,
"loss_toxic": 0.0953175767014424
},
{
"loss": 0.9160839451683892,
"loss_size": 0.3149913748105367,
"loss_pdi": 0.5144901672999064,
"loss_ee": 0.774557027551863,
"loss_delivery": 0.25001151031917995,
"loss_biodist": 0.24419869813654158,
"loss_toxic": 0.07320865222977267
},
{
"loss": 0.8772096435228983,
"loss_size": 0.3025674472252528,
"loss_pdi": 0.5610448817412058,
"loss_ee": 0.7567994528346591,
"loss_delivery": 0.22850145482354695,
"loss_biodist": 0.21544894907209608,
"loss_toxic": 0.1529837174134122
},
{
"loss": 0.7775394055578444,
"loss_size": 0.3007944855425093,
"loss_pdi": 0.4857555462254418,
"loss_ee": 0.7410714824994405,
"loss_delivery": 0.19621007723940742,
"loss_biodist": 0.17948989735709298,
"loss_toxic": 0.07423716680043274
},
{
"loss": 0.7944639656278822,
"loss_size": 0.2702309058772193,
"loss_pdi": 0.4726009998056624,
"loss_ee": 0.7363064885139465,
"loss_delivery": 0.2161275852057669,
"loss_biodist": 0.18517516056696573,
"loss_toxic": 0.0693175916870435
},
{
"loss": 0.868152896563212,
"loss_size": 0.353721742828687,
"loss_pdi": 0.4352845251560211,
"loss_ee": 0.7311722040176392,
"loss_delivery": 0.28572942813237506,
"loss_biodist": 0.19355661670366922,
"loss_toxic": 0.0711525229530202
},
{
"loss": 0.8229561845461527,
"loss_size": 0.2390851258403725,
"loss_pdi": 0.46370699008305866,
"loss_ee": 0.7129934430122375,
"loss_delivery": 0.2797413269678752,
"loss_biodist": 0.163183750377761,
"loss_toxic": 0.06224951727522744
},
{
"loss": 0.7073442074987624,
"loss_size": 0.26570335858398014,
"loss_pdi": 0.46388477583726245,
"loss_ee": 0.6822554535335965,
"loss_delivery": 0.17277332146962485,
"loss_biodist": 0.1576644563012653,
"loss_toxic": 0.12988046194530195
},
{
"loss": 0.7495085597038269,
"loss_size": 0.2469803144534429,
"loss_pdi": 0.4163050187958611,
"loss_ee": 0.6714508732159933,
"loss_delivery": 0.19608071777555677,
"loss_biodist": 0.19968150473303264,
"loss_toxic": 0.0544304313759009
},
{
"loss": 0.6928741534550985,
"loss_size": 0.24070869634548822,
"loss_pdi": 0.41940996381971574,
"loss_ee": 0.6891013185183207,
"loss_delivery": 0.1789121168355147,
"loss_biodist": 0.15480930854876837,
"loss_toxic": 0.05056922800011105
},
{
"loss": 0.6773558722601997,
"loss_size": 0.22304456846581566,
"loss_pdi": 0.4265521698527866,
"loss_ee": 0.6338741183280945,
"loss_delivery": 0.20091451042228275,
"loss_biodist": 0.13308443625768027,
"loss_toxic": 0.05849140344394578
},
{
"loss": 0.6792458958095975,
"loss_size": 0.18910101883941227,
"loss_pdi": 0.4736470646328396,
"loss_ee": 0.6600266562567817,
"loss_delivery": 0.17967590772443348,
"loss_biodist": 0.137747993071874,
"loss_toxic": 0.0561952812390195
},
{
"loss": 0.7022113071547614,
"loss_size": 0.2158840306931072,
"loss_pdi": 0.43700193696551853,
"loss_ee": 0.6360369854503207,
"loss_delivery": 0.20829415652487013,
"loss_biodist": 0.14777151660786736,
"loss_toxic": 0.052910939065946475
},
{
"loss": 0.6449441247516208,
"loss_size": 0.1952553109990226,
"loss_pdi": 0.3760784930653042,
"loss_ee": 0.6379995346069336,
"loss_delivery": 0.16369475175937018,
"loss_biodist": 0.1552567192249828,
"loss_toxic": 0.04487405986421638
},
{
"loss": 0.6427479816807641,
"loss_size": 0.23657568130228254,
"loss_pdi": 0.372259345319536,
"loss_ee": 0.6441503597630395,
"loss_delivery": 0.14370831184917027,
"loss_biodist": 0.16797509872251087,
"loss_toxic": 0.04968215307841698
},
{
"loss": 0.9931288758913676,
"loss_size": 0.19573548601733315,
"loss_pdi": 0.3725646701123979,
"loss_ee": 0.677657683690389,
"loss_delivery": 0.46030762253536117,
"loss_biodist": 0.1962142065167427,
"loss_toxic": 0.03933604992926121
},
{
"loss": 0.6079309384028116,
"loss_size": 0.21275880187749863,
"loss_pdi": 0.34046634534994763,
"loss_ee": 0.6355888280603621,
"loss_delivery": 0.1639514739314715,
"loss_biodist": 0.12741477456357744,
"loss_toxic": 0.049445086986654334
},
{
"loss": 0.6870207786560059,
"loss_size": 0.2087610380517112,
"loss_pdi": 0.3540271148085594,
"loss_ee": 0.5907266206211514,
"loss_delivery": 0.18505429559283787,
"loss_biodist": 0.19559555831882688,
"loss_toxic": 0.04137388596104251
},
{
"loss": 0.6472303436862098,
"loss_size": 0.22184482299619251,
"loss_pdi": 0.4683272573682997,
"loss_ee": 0.5644559562206268,
"loss_delivery": 0.19896187633275986,
"loss_biodist": 0.11412501914633645,
"loss_toxic": 0.042479665846460395
},
{
"loss": 0.5487931172053019,
"loss_size": 0.17582466204961142,
"loss_pdi": 0.32146011624071336,
"loss_ee": 0.5250605924261941,
"loss_delivery": 0.15071064192387792,
"loss_biodist": 0.1245238913430108,
"loss_toxic": 0.04039790424414807
},
{
"loss": 0.5697314010726081,
"loss_size": 0.21712515585952336,
"loss_pdi": 0.3176909022861057,
"loss_ee": 0.5787608093685574,
"loss_delivery": 0.13063641844524276,
"loss_biodist": 0.1464226171374321,
"loss_toxic": 0.040486347033745713
},
{
"loss": 0.5647341542773776,
"loss_size": 0.2063691798183653,
"loss_pdi": 0.38127953476376003,
"loss_ee": 0.563402748770184,
"loss_delivery": 0.132879844142331,
"loss_biodist": 0.12596635396281877,
"loss_toxic": 0.036926837586280375
},
{
"loss": 0.5067204071415795,
"loss_size": 0.23850117623806,
"loss_pdi": 0.2924792087740368,
"loss_ee": 0.5628483295440674,
"loss_delivery": 0.12116432148549292,
"loss_biodist": 0.10345037281513214,
"loss_toxic": 0.03314654971472919
},
{
"loss": 1.0699441101815965,
"loss_size": 0.17469535105758244,
"loss_pdi": 0.3502203706238005,
"loss_ee": 0.5562509695688883,
"loss_delivery": 0.6446112332244714,
"loss_biodist": 0.13430255237552854,
"loss_toxic": 0.032387840251127877
},
{
"loss": 0.5611699124177297,
"loss_size": 0.16061691443125406,
"loss_pdi": 0.3454722497198317,
"loss_ee": 0.5293509198559655,
"loss_delivery": 0.16204639772574106,
"loss_biodist": 0.11875326765908135,
"loss_toxic": 0.037232138216495514
},
{
"loss": 0.530913253625234,
"loss_size": 0.18493542157941395,
"loss_pdi": 0.29415023658010697,
"loss_ee": 0.595608608590232,
"loss_delivery": 0.12832303759124544,
"loss_biodist": 0.11531495137347116,
"loss_toxic": 0.037081255629244775
},
{
"loss": 0.46351798706584507,
"loss_size": 0.19074936790598762,
"loss_pdi": 0.2951990183856752,
"loss_ee": 0.4819436338212755,
"loss_delivery": 0.10374879505899218,
"loss_biodist": 0.10574217471811506,
"loss_toxic": 0.0361855471920636
},
{
"loss": 0.4980843596988254,
"loss_size": 0.1467754857407676,
"loss_pdi": 0.28184814916716683,
"loss_ee": 0.5108992391162448,
"loss_delivery": 0.13626391523414189,
"loss_biodist": 0.10757666081190109,
"loss_toxic": 0.03484007234995564
},
{
"loss": 0.47234705090522766,
"loss_size": 0.18433138065867954,
"loss_pdi": 0.29718642433484393,
"loss_ee": 0.4984990590148502,
"loss_delivery": 0.11131453679667579,
"loss_biodist": 0.10233025832308663,
"loss_toxic": 0.031269495685895286
},
{
"loss": 0.49952124224768746,
"loss_size": 0.15636196939481628,
"loss_pdi": 0.2847433520687951,
"loss_ee": 0.48881187703874374,
"loss_delivery": 0.1531598741809527,
"loss_biodist": 0.09685589538680182,
"loss_toxic": 0.03605382113407055
},
{
"loss": 0.5008097920152876,
"loss_size": 0.17970380518171522,
"loss_pdi": 0.2696686072482003,
"loss_ee": 0.5016761455270979,
"loss_delivery": 0.1433546224402057,
"loss_biodist": 0.10643771621916029,
"loss_toxic": 0.032872507296916514
}
],
"val": [
{
"loss": 4.352981249491374,
"loss_size": 14.040823618570963,
"loss_pdi": 1.1560964584350586,
"loss_ee": 1.0625061988830566,
"loss_delivery": 1.0593002637227376,
"loss_biodist": 1.192948619524638,
"loss_toxic": 0.6213847597440084,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.47126436781609193,
"acc_toxic": 0.9
},
{
"loss": 3.3357954025268555,
"loss_size": 6.06112019220988,
"loss_pdi": 0.968859871228536,
"loss_ee": 1.0026604334513347,
"loss_delivery": 0.9897311329841614,
"loss_biodist": 1.125332196553548,
"loss_toxic": 0.4632777273654938,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.5517241379310345,
"acc_toxic": 0.9166666666666666
},
{
"loss": 2.767303546269735,
"loss_size": 1.818801999092102,
"loss_pdi": 0.8547852834065756,
"loss_ee": 0.9709142843882242,
"loss_delivery": 0.9232005079587301,
"loss_biodist": 1.0974398056666057,
"loss_toxic": 0.34146594007809955,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.5517241379310345,
"acc_toxic": 0.9166666666666666
},
{
"loss": 2.4660185178120932,
"loss_size": 0.2837679435809453,
"loss_pdi": 0.7920133868853251,
"loss_ee": 0.9490573604901632,
"loss_delivery": 0.9340477387110392,
"loss_biodist": 0.966218888759613,
"loss_toxic": 0.30107616384824115,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.5517241379310345,
"acc_toxic": 0.9166666666666666
},
{
"loss": 2.2471745014190674,
"loss_size": 0.12167477607727051,
"loss_pdi": 0.7561964591344198,
"loss_ee": 0.9035918911298116,
"loss_delivery": 0.8805848260720571,
"loss_biodist": 0.8411766688028971,
"loss_toxic": 0.306180939078331,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.6885152260462444,
"loss_size": 0.16249329845110574,
"loss_pdi": 0.7185025413831075,
"loss_ee": 0.834699809551239,
"loss_delivery": 0.6471298635005951,
"loss_biodist": 0.5438492397467295,
"loss_toxic": 0.306520755092303,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.4998847246170044,
"loss_size": 0.17702753841876984,
"loss_pdi": 0.6977987885475159,
"loss_ee": 0.8065251111984253,
"loss_delivery": 0.5934116542339325,
"loss_biodist": 0.4223662813504537,
"loss_toxic": 0.3021365900834401,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.4727789958318074,
"loss_size": 0.1332696924606959,
"loss_pdi": 0.7014670769373575,
"loss_ee": 0.7922239502271017,
"loss_delivery": 0.638674815495809,
"loss_biodist": 0.35675326983133954,
"loss_toxic": 0.31833313405513763,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.436899224917094,
"loss_size": 0.13452864935000738,
"loss_pdi": 0.684553881486257,
"loss_ee": 0.7653761506080627,
"loss_delivery": 0.6407908201217651,
"loss_biodist": 0.33279359340667725,
"loss_toxic": 0.2976590593655904,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.2208503484725952,
"loss_size": 0.16631528735160828,
"loss_pdi": 0.6577734549840292,
"loss_ee": 0.7665876547495524,
"loss_delivery": 0.48486973841985065,
"loss_biodist": 0.2789425750573476,
"loss_toxic": 0.2619628707567851,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.248612880706787,
"loss_size": 0.18232750395933786,
"loss_pdi": 0.649429460366567,
"loss_ee": 0.7502844929695129,
"loss_delivery": 0.532643457253774,
"loss_biodist": 0.26479581991831463,
"loss_toxic": 0.26053250829378766,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.6551724137931034,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.2217957576115925,
"loss_size": 0.14767353733380637,
"loss_pdi": 0.6429043213526408,
"loss_ee": 0.725229024887085,
"loss_delivery": 0.5429440836111704,
"loss_biodist": 0.24105359613895416,
"loss_toxic": 0.2518138339122136,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1423648993174236,
"loss_size": 0.138336310784022,
"loss_pdi": 0.64690101146698,
"loss_ee": 0.719541589419047,
"loss_delivery": 0.49121378858884174,
"loss_biodist": 0.21493942538897196,
"loss_toxic": 0.24890372653802237,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1333981553713481,
"loss_size": 0.11350886523723602,
"loss_pdi": 0.6397646268208822,
"loss_ee": 0.7264792521794637,
"loss_delivery": 0.49360715846220654,
"loss_biodist": 0.2063005566596985,
"loss_toxic": 0.2453270231684049,
"acc_pdi": 0.6781609195402298,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1487789750099182,
"loss_size": 0.13474328319231668,
"loss_pdi": 0.6321920355161031,
"loss_ee": 0.6919702887535095,
"loss_delivery": 0.5112977822621664,
"loss_biodist": 0.2153903047243754,
"loss_toxic": 0.22735604147116342,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0790208578109741,
"loss_size": 0.1243719110886256,
"loss_pdi": 0.6189361015955607,
"loss_ee": 0.6877770821253458,
"loss_delivery": 0.4728225767612457,
"loss_biodist": 0.19130249321460724,
"loss_toxic": 0.20889216164747873,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1575236916542053,
"loss_size": 0.13228566199541092,
"loss_pdi": 0.6147287487983704,
"loss_ee": 0.6828009486198425,
"loss_delivery": 0.548195093870163,
"loss_biodist": 0.1973088284333547,
"loss_toxic": 0.19064538180828094,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1351452271143596,
"loss_size": 0.19023342927296957,
"loss_pdi": 0.6062304774920145,
"loss_ee": 0.6876464287439982,
"loss_delivery": 0.5415350496768951,
"loss_biodist": 0.1771141936381658,
"loss_toxic": 0.18619074299931526,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1262837251027424,
"loss_size": 0.12486698726812999,
"loss_pdi": 0.6214810411135355,
"loss_ee": 0.6816250085830688,
"loss_delivery": 0.5331919093926748,
"loss_biodist": 0.17967281738917032,
"loss_toxic": 0.2000091386338075,
"acc_pdi": 0.6781609195402298,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0970223148663838,
"loss_size": 0.1257863367597262,
"loss_pdi": 0.6169956723848978,
"loss_ee": 0.674238363901774,
"loss_delivery": 0.5013431708017985,
"loss_biodist": 0.1856648474931717,
"loss_toxic": 0.20130913704633713,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.7471264367816092,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.099283218383789,
"loss_size": 0.1544548769791921,
"loss_pdi": 0.6007954875628153,
"loss_ee": 0.6859760681788126,
"loss_delivery": 0.5206386148929596,
"loss_biodist": 0.16801170508066812,
"loss_toxic": 0.18311957145730653,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0425826509793599,
"loss_size": 0.12690149744351706,
"loss_pdi": 0.609094520409902,
"loss_ee": 0.6826133529345194,
"loss_delivery": 0.4732641627391179,
"loss_biodist": 0.1601690575480461,
"loss_toxic": 0.17893838013211885,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0118964711825054,
"loss_size": 0.12006142735481262,
"loss_pdi": 0.6105441848436991,
"loss_ee": 0.6461567282676697,
"loss_delivery": 0.4406776974598567,
"loss_biodist": 0.17357941965262094,
"loss_toxic": 0.1724582016468048,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0085107485453289,
"loss_size": 0.12090034286181132,
"loss_pdi": 0.620375374952952,
"loss_ee": 0.657938539981842,
"loss_delivery": 0.441881130139033,
"loss_biodist": 0.16284615794817606,
"loss_toxic": 0.16398430491487184,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.95
},
{
"loss": 0.9860520362854004,
"loss_size": 0.12217508753140767,
"loss_pdi": 0.6206247607866923,
"loss_ee": 0.6440999905268351,
"loss_delivery": 0.4378689130147298,
"loss_biodist": 0.14770600944757462,
"loss_toxic": 0.17684349541862807,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9333333333333333
},
{
"loss": 1.0554319620132446,
"loss_size": 0.12288897732893626,
"loss_pdi": 0.632273813088735,
"loss_ee": 0.6358709534009298,
"loss_delivery": 0.5059696435928345,
"loss_biodist": 0.1477027634779612,
"loss_toxic": 0.18054372444748878,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.735632183908046,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.121798833211263,
"loss_size": 0.12404415508111317,
"loss_pdi": 0.6373317837715149,
"loss_ee": 0.6587992707888285,
"loss_delivery": 0.5559230248133341,
"loss_biodist": 0.15606074780225754,
"loss_toxic": 0.1714273082713286,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.1430274844169617,
"loss_size": 0.11301922301451366,
"loss_pdi": 0.6578433911005656,
"loss_ee": 0.6824644605318705,
"loss_delivery": 0.5535165766874949,
"loss_biodist": 0.16838948925336203,
"loss_toxic": 0.15454251070817313,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.95
},
{
"loss": 1.0789345304171245,
"loss_size": 0.12665234754482904,
"loss_pdi": 0.628511369228363,
"loss_ee": 0.6637401580810547,
"loss_delivery": 0.5144663751125336,
"loss_biodist": 0.15651273975769678,
"loss_toxic": 0.15229505797227225,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.95
},
{
"loss": 1.1036843061447144,
"loss_size": 0.14210577557484308,
"loss_pdi": 0.6573460300763448,
"loss_ee": 0.654138445854187,
"loss_delivery": 0.5199695527553558,
"loss_biodist": 0.16731185962756476,
"loss_toxic": 0.17493977646032968,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9166666666666666
},
{
"loss": 1.0917064348856609,
"loss_size": 0.13055240114529928,
"loss_pdi": 0.674348791440328,
"loss_ee": 0.6479312082131704,
"loss_delivery": 0.5166832506656647,
"loss_biodist": 0.15717355906963348,
"loss_toxic": 0.16220672490696111,
"acc_pdi": 0.6781609195402298,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.95
},
{
"loss": 1.0822275678316753,
"loss_size": 0.11884492387374242,
"loss_pdi": 0.6784968773523966,
"loss_ee": 0.6504894097646078,
"loss_delivery": 0.4989545742670695,
"loss_biodist": 0.1650076930721601,
"loss_toxic": 0.1536990733196338,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.95
},
{
"loss": 1.0770344138145447,
"loss_size": 0.1161716878414154,
"loss_pdi": 0.6677623788515726,
"loss_ee": 0.6809870998064677,
"loss_delivery": 0.49489422639211017,
"loss_biodist": 0.15819709499677023,
"loss_toxic": 0.15402085644503435,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.95
},
{
"loss": 1.136393924554189,
"loss_size": 0.15242908398310342,
"loss_pdi": 0.6701520085334778,
"loss_ee": 0.6857072114944458,
"loss_delivery": 0.5439692536989847,
"loss_biodist": 0.16289545595645905,
"loss_toxic": 0.1505710215618213,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.95
},
{
"loss": 1.1579704682032268,
"loss_size": 0.1452335019906362,
"loss_pdi": 0.6537480354309082,
"loss_ee": 0.6724907457828522,
"loss_delivery": 0.5718408127625784,
"loss_biodist": 0.16647989302873611,
"loss_toxic": 0.14509441889822483,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9666666666666667
},
{
"loss": 1.1262755990028381,
"loss_size": 0.14492533107598624,
"loss_pdi": 0.6638315717379252,
"loss_ee": 0.6787967483202616,
"loss_delivery": 0.5302154620488485,
"loss_biodist": 0.17137336979309717,
"loss_toxic": 0.1481148942063252,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9666666666666667
},
{
"loss": 1.1905850966771443,
"loss_size": 0.1757280578215917,
"loss_pdi": 0.6594760616620382,
"loss_ee": 0.6702400048573812,
"loss_delivery": 0.606451948483785,
"loss_biodist": 0.1602563038468361,
"loss_toxic": 0.14778405365844569,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9666666666666667
},
{
"loss": 1.2040231227874756,
"loss_size": 0.16256481409072876,
"loss_pdi": 0.6649826169013977,
"loss_ee": 0.6746243834495544,
"loss_delivery": 0.6194721460342407,
"loss_biodist": 0.15908189614613852,
"loss_toxic": 0.1466086314370235,
"acc_pdi": 0.7011494252873564,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9666666666666667
},
{
"loss": 1.1368837753931682,
"loss_size": 0.13984778026739755,
"loss_pdi": 0.6734874248504639,
"loss_ee": 0.688675065835317,
"loss_delivery": 0.552798459927241,
"loss_biodist": 0.15415997554858527,
"loss_toxic": 0.14583549462258816,
"acc_pdi": 0.6781609195402298,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9666666666666667
},
{
"loss": 1.1671558221181233,
"loss_size": 0.14158056179682413,
"loss_pdi": 0.6789752840995789,
"loss_ee": 0.6732718547185262,
"loss_delivery": 0.5818846722443899,
"loss_biodist": 0.15803349514802298,
"loss_toxic": 0.14810880708197752,
"acc_pdi": 0.6896551724137931,
"acc_ee": 0.6551724137931034,
"acc_toxic": 0.9666666666666667
}
]
}

BIN
models/finetune_cv/fold_0/loss_curves.png
View File

Binary file not shown.
Side by Side

Before

Width:  |  Height:  |  Size: 287 KiB

3
models/finetune_cv/fold_0/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:c237d49148718c53e6218d15ce4b8698620871f2a67580af3a7769e9e477aa3b
size 28583404

804
models/finetune_cv/fold_1/history.json
View File

@ -1,804 +0,0 @@
{
"train": [
{
"loss": 4.483094983630711,
"loss_size": 17.799428092108833,
"loss_pdi": 1.3262000878651936,
"loss_ee": 1.1150687270694308,
"loss_delivery": 0.7627770271566179,
"loss_biodist": 1.1767686075634427,
"loss_toxic": 0.6245201097594367
},
{
"loss": 3.1453810267978244,
"loss_size": 10.030321174197727,
"loss_pdi": 1.1304074658287897,
"loss_ee": 1.03237388531367,
"loss_delivery": 0.5101837151580386,
"loss_biodist": 0.9600839018821716,
"loss_toxic": 0.4649372266398536
},
{
"loss": 2.32554382748074,
"loss_size": 4.4059361881679955,
"loss_pdi": 0.9423307842678494,
"loss_ee": 0.9478094114197625,
"loss_delivery": 0.4923851001593802,
"loss_biodist": 0.8092087639702691,
"loss_toxic": 0.3262847893767887
},
{
"loss": 1.738295104768541,
"loss_size": 1.5802081988917456,
"loss_pdi": 0.7814622587627835,
"loss_ee": 0.8929457267125448,
"loss_delivery": 0.3846158550845252,
"loss_biodist": 0.6821949548191495,
"loss_toxic": 0.22282126380337608
},
{
"loss": 1.5327205393049452,
"loss_size": 0.6663399123483233,
"loss_pdi": 0.7942536075909933,
"loss_ee": 0.9184659785694547,
"loss_delivery": 0.40279845727814567,
"loss_biodist": 0.5410700175497267,
"loss_toxic": 0.16804325332244238
},
{
"loss": 1.434507237540351,
"loss_size": 0.5797484550211165,
"loss_pdi": 0.6577127542760637,
"loss_ee": 0.8519722157054477,
"loss_delivery": 0.4511991755829917,
"loss_biodist": 0.46546968155437046,
"loss_toxic": 0.139161123169793
},
{
"loss": 1.157564017507765,
"loss_size": 0.4058436047699716,
"loss_pdi": 0.6451378762722015,
"loss_ee": 0.860814372698466,
"loss_delivery": 0.2965482622385025,
"loss_biodist": 0.3622526211871041,
"loss_toxic": 0.12786167073580954
},
{
"loss": 1.1518061492178175,
"loss_size": 0.3752725480331315,
"loss_pdi": 0.5965503421094682,
"loss_ee": 0.7964835895432366,
"loss_delivery": 0.3263945099380281,
"loss_biodist": 0.3639618323908912,
"loss_toxic": 0.12024733300010364
},
{
"loss": 1.0457552538977728,
"loss_size": 0.39199402762783897,
"loss_pdi": 0.5741230414973365,
"loss_ee": 0.8501448167694939,
"loss_delivery": 0.28289384653584826,
"loss_biodist": 0.2912274483177397,
"loss_toxic": 0.103083159464101
},
{
"loss": 1.0246235065990024,
"loss_size": 0.40383457640806836,
"loss_pdi": 0.6044520669513278,
"loss_ee": 0.838128560119205,
"loss_delivery": 0.29832789964146084,
"loss_biodist": 0.2480060930053393,
"loss_toxic": 0.10263721272349358
},
{
"loss": 0.9804655512173971,
"loss_size": 0.3403070982959535,
"loss_pdi": 0.586881117688285,
"loss_ee": 0.7934199968973795,
"loss_delivery": 0.2985777755578359,
"loss_biodist": 0.22911010020309025,
"loss_toxic": 0.09313236466712421
},
{
"loss": 0.9875470002492269,
"loss_size": 0.3532874650425381,
"loss_pdi": 0.5827326476573944,
"loss_ee": 0.7857406669192843,
"loss_delivery": 0.32336633404095966,
"loss_biodist": 0.21369437707795036,
"loss_toxic": 0.09231033962633875
},
{
"loss": 0.9134721093707614,
"loss_size": 0.3020283199018902,
"loss_pdi": 0.5080229540665945,
"loss_ee": 0.7729690935876634,
"loss_delivery": 0.2812257359425227,
"loss_biodist": 0.21345127456718022,
"loss_toxic": 0.08589264108902878
},
{
"loss": 1.0202063057157729,
"loss_size": 0.24574599828985003,
"loss_pdi": 0.5134079158306122,
"loss_ee": 0.7183774643474155,
"loss_delivery": 0.43278445220655865,
"loss_biodist": 0.18915812836753,
"loss_toxic": 0.08306968067255285
},
{
"loss": 0.837601469622718,
"loss_size": 0.2501253742310736,
"loss_pdi": 0.5269780258337656,
"loss_ee": 0.7272330522537231,
"loss_delivery": 0.2580337930056784,
"loss_biodist": 0.17455370558632743,
"loss_toxic": 0.07476167794730929
},
{
"loss": 0.8901008499993218,
"loss_size": 0.288739949464798,
"loss_pdi": 0.4844526946544647,
"loss_ee": 0.7501750588417053,
"loss_delivery": 0.2808743309643533,
"loss_biodist": 0.20616857541932,
"loss_toxic": 0.07591219732744826
},
{
"loss": 0.909783575269911,
"loss_size": 0.34342534343401593,
"loss_pdi": 0.4743039641115401,
"loss_ee": 0.7001715633604262,
"loss_delivery": 0.22445038043790394,
"loss_biodist": 0.2948597628209326,
"loss_toxic": 0.07576444931328297
},
{
"loss": 0.9337513777944777,
"loss_size": 0.30651744041177964,
"loss_pdi": 0.522970567146937,
"loss_ee": 0.672338863213857,
"loss_delivery": 0.34812434514363605,
"loss_biodist": 0.1913993482788404,
"loss_toxic": 0.09966130327019426
},
{
"loss": 0.88894122838974,
"loss_size": 0.20973580992884105,
"loss_pdi": 0.4721333185831706,
"loss_ee": 0.6787008775605096,
"loss_delivery": 0.3628806521495183,
"loss_biodist": 0.15672991342014736,
"loss_toxic": 0.06213616424550613
},
{
"loss": 1.5575014154116313,
"loss_size": 0.2698170675171746,
"loss_pdi": 0.4372737639480167,
"loss_ee": 0.6038656400309669,
"loss_delivery": 1.0306985912223656,
"loss_biodist": 0.18247240864568287,
"loss_toxic": 0.10013543855812815
},
{
"loss": 0.71677123175727,
"loss_size": 0.2442774698138237,
"loss_pdi": 0.4490685794088576,
"loss_ee": 0.6365031997362772,
"loss_delivery": 0.2200260336200396,
"loss_biodist": 0.1435830278529061,
"loss_toxic": 0.06125718168914318
},
{
"loss": 0.8792243599891663,
"loss_size": 0.2384073461095492,
"loss_pdi": 0.42239466143978965,
"loss_ee": 0.6093993948565589,
"loss_delivery": 0.3219309722383817,
"loss_biodist": 0.22114951494667265,
"loss_toxic": 0.05529743950400087
},
{
"loss": 0.733058836725023,
"loss_size": 0.23823850767480004,
"loss_pdi": 0.425810757610533,
"loss_ee": 0.6325586239496866,
"loss_delivery": 0.2243285659286711,
"loss_biodist": 0.16463084684477913,
"loss_toxic": 0.05529523640871048
},
{
"loss": 0.6581202414300706,
"loss_size": 0.20839755651023653,
"loss_pdi": 0.4217190808720059,
"loss_ee": 0.5873864591121674,
"loss_delivery": 0.19784662458631727,
"loss_biodist": 0.13395333952373928,
"loss_toxic": 0.05497736711468962
},
{
"loss": 0.7765605052312216,
"loss_size": 0.24175780183739132,
"loss_pdi": 0.4168710211912791,
"loss_ee": 0.6162208616733551,
"loss_delivery": 0.2875041738152504,
"loss_biodist": 0.15230030732022393,
"loss_toxic": 0.0530535995753275
},
{
"loss": 0.9171080787976583,
"loss_size": 0.1859503620200687,
"loss_pdi": 0.4959961308373345,
"loss_ee": 0.6685057216220431,
"loss_delivery": 0.4157853250702222,
"loss_biodist": 0.1305243612991439,
"loss_toxic": 0.05705541041162279
},
{
"loss": 0.9473238223128848,
"loss_size": 0.2332402682966656,
"loss_pdi": 0.4101437230904897,
"loss_ee": 0.6192202501826816,
"loss_delivery": 0.4859153628349304,
"loss_biodist": 0.12654284056690004,
"loss_toxic": 0.0546483112913039
},
{
"loss": 0.6730706261263953,
"loss_size": 0.17648173951440388,
"loss_pdi": 0.4805830717086792,
"loss_ee": 0.5886320769786835,
"loss_delivery": 0.18041609476010004,
"loss_biodist": 0.14861485527621376,
"loss_toxic": 0.11253876187321213
},
{
"loss": 0.6988482276598612,
"loss_size": 0.25076936847633785,
"loss_pdi": 0.44280703531371224,
"loss_ee": 0.6034945580694411,
"loss_delivery": 0.16704336553812027,
"loss_biodist": 0.18480077551470864,
"loss_toxic": 0.16073330719437864
},
{
"loss": 0.6114611426989237,
"loss_size": 0.17417494994070795,
"loss_pdi": 0.4592122832934062,
"loss_ee": 0.5821059809790717,
"loss_delivery": 0.1583896146880256,
"loss_biodist": 0.12043732487493092,
"loss_toxic": 0.05642468678868479
},
{
"loss": 0.6659026841322581,
"loss_size": 0.1813880147205459,
"loss_pdi": 0.44227521618207294,
"loss_ee": 0.5675410595205095,
"loss_delivery": 0.22069326601922512,
"loss_biodist": 0.1209203443593449,
"loss_toxic": 0.0641073149939378
},
{
"loss": 0.6743504338794284,
"loss_size": 0.34597602238257724,
"loss_pdi": 0.438336302836736,
"loss_ee": 0.6530322763654921,
"loss_delivery": 0.1414711625354054,
"loss_biodist": 0.16852128257354101,
"loss_toxic": 0.0469961882982817
},
{
"loss": 0.6300642788410187,
"loss_size": 0.2032055366370413,
"loss_pdi": 0.40160394708315533,
"loss_ee": 0.5567268431186676,
"loss_delivery": 0.1769900479250484,
"loss_biodist": 0.14295541081163618,
"loss_toxic": 0.045980457992603384
},
{
"loss": 0.6177813212076823,
"loss_size": 0.2232944874299897,
"loss_pdi": 0.38791416419876945,
"loss_ee": 0.6102284689744314,
"loss_delivery": 0.18632310214969847,
"loss_biodist": 0.10720572868982951,
"loss_toxic": 0.04960477910935879
},
{
"loss": 0.613649007346895,
"loss_size": 0.23112748066584268,
"loss_pdi": 0.46902064482371014,
"loss_ee": 0.5577017333772447,
"loss_delivery": 0.1482661927325858,
"loss_biodist": 0.13032738119363785,
"loss_toxic": 0.07851899084117678
},
{
"loss": 0.5897228784031339,
"loss_size": 0.17141623629464042,
"loss_pdi": 0.4236266745461358,
"loss_ee": 0.5572320090399848,
"loss_delivery": 0.16153137737678158,
"loss_biodist": 0.11331264509095086,
"loss_toxic": 0.0695920708692736
},
{
"loss": 0.5882392525672913,
"loss_size": 0.18827490508556366,
"loss_pdi": 0.39782606893115574,
"loss_ee": 0.5966229869259728,
"loss_delivery": 0.1632317118346691,
"loss_biodist": 0.10572336945268843,
"loss_toxic": 0.04243891453370452
},
{
"loss": 0.564177993271086,
"loss_size": 0.1795721153418223,
"loss_pdi": 0.38133784135182697,
"loss_ee": 0.5388166175948249,
"loss_delivery": 0.15948744035429424,
"loss_biodist": 0.10809837530056636,
"loss_toxic": 0.051772640397151314
}
],
"val": [
{
"loss": 5.620796839396159,
"loss_size": 16.616828600565594,
"loss_pdi": 1.1196924448013306,
"loss_ee": 1.0096928477287292,
"loss_delivery": 2.169648289680481,
"loss_biodist": 1.1206785043080647,
"loss_toxic": 0.5994243224461874,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.8923076923076924
},
{
"loss": 4.4913545449574785,
"loss_size": 8.50448751449585,
"loss_pdi": 0.9723374644915262,
"loss_ee": 0.9344328045845032,
"loss_delivery": 2.08004825313886,
"loss_biodist": 0.9655160705248514,
"loss_toxic": 0.4662085672219594,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9230769230769231
},
{
"loss": 3.708923816680908,
"loss_size": 2.978870073954264,
"loss_pdi": 0.8018507162729899,
"loss_ee": 0.8843226035435995,
"loss_delivery": 2.038456469774246,
"loss_biodist": 0.8491520881652832,
"loss_toxic": 0.3515246858199437,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9230769230769231
},
{
"loss": 3.2127588987350464,
"loss_size": 0.9111812313397726,
"loss_pdi": 0.6809012293815613,
"loss_ee": 0.8370791077613831,
"loss_delivery": 1.900310883919398,
"loss_biodist": 0.7513505816459656,
"loss_toxic": 0.2917053947846095,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9230769230769231
},
{
"loss": 3.014926473299662,
"loss_size": 0.3419476201136907,
"loss_pdi": 0.6159671545028687,
"loss_ee": 0.7953161001205444,
"loss_delivery": 1.9890191306670506,
"loss_biodist": 0.5549481411774954,
"loss_toxic": 0.2675894424319267,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.7700488169988,
"loss_size": 0.3060595542192459,
"loss_pdi": 0.6163395444552103,
"loss_ee": 0.8149995605150858,
"loss_delivery": 1.8813785662253697,
"loss_biodist": 0.41590667764345807,
"loss_toxic": 0.25511589522163075,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.673178176085154,
"loss_size": 0.2623714804649353,
"loss_pdi": 0.6015681624412537,
"loss_ee": 0.8224873145421346,
"loss_delivery": 1.880643054842949,
"loss_biodist": 0.3274502952893575,
"loss_toxic": 0.23262197648485503,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.6218310991923013,
"loss_size": 0.259665347635746,
"loss_pdi": 0.5827788909276327,
"loss_ee": 0.8258134524027506,
"loss_delivery": 1.8505116403102875,
"loss_biodist": 0.31070442497730255,
"loss_toxic": 0.2414170385648807,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.5716400941212973,
"loss_size": 0.30026574432849884,
"loss_pdi": 0.5709420243899027,
"loss_ee": 0.8006119330724081,
"loss_delivery": 1.8458916743596394,
"loss_biodist": 0.27388909459114075,
"loss_toxic": 0.20732813949386278,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.579125980536143,
"loss_size": 0.2999979977806409,
"loss_pdi": 0.5409552355607351,
"loss_ee": 0.7766269644101461,
"loss_delivery": 1.8966593717535336,
"loss_biodist": 0.24749354521433511,
"loss_toxic": 0.19397167240579924,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.52097753683726,
"loss_size": 0.33180438230435055,
"loss_pdi": 0.5372390250364939,
"loss_ee": 0.8088536858558655,
"loss_delivery": 1.8541920805970828,
"loss_biodist": 0.22186783452828726,
"loss_toxic": 0.15818508279820284,
"acc_pdi": 0.8045977011494253,
"acc_ee": 0.6091954022988506,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.4966036876042685,
"loss_size": 0.3201774259408315,
"loss_pdi": 0.5286376774311066,
"loss_ee": 0.7662556767463684,
"loss_delivery": 1.8560101017355919,
"loss_biodist": 0.21296357115109762,
"loss_toxic": 0.1428842805325985,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.6091954022988506,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.6487866242726645,
"loss_size": 0.29212243606646854,
"loss_pdi": 0.5578331450621287,
"loss_ee": 0.7530265847841898,
"loss_delivery": 2.0136459320783615,
"loss_biodist": 0.20620496571063995,
"loss_toxic": 0.12930945244928202,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.5862068965517241,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.4672120412190757,
"loss_size": 0.275730441013972,
"loss_pdi": 0.5478581587473551,
"loss_ee": 0.7905668020248413,
"loss_delivery": 1.8320665483673413,
"loss_biodist": 0.1998033324877421,
"loss_toxic": 0.12483249666790168,
"acc_pdi": 0.7931034482758621,
"acc_ee": 0.6091954022988506,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.5560020804405212,
"loss_size": 0.28637858976920444,
"loss_pdi": 0.5347247123718262,
"loss_ee": 0.7782952388127645,
"loss_delivery": 1.9329951107501984,
"loss_biodist": 0.19475139180819193,
"loss_toxic": 0.1142334205408891,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.5862068965517241,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.5079132517178855,
"loss_size": 0.29228730996449787,
"loss_pdi": 0.523117740948995,
"loss_ee": 0.7234304149945577,
"loss_delivery": 1.9079867253700893,
"loss_biodist": 0.19056849678357443,
"loss_toxic": 0.12329485639929771,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.5535390774408975,
"loss_size": 0.3006244997183482,
"loss_pdi": 0.5052263538042704,
"loss_ee": 0.730924129486084,
"loss_delivery": 1.9523295412460964,
"loss_biodist": 0.19413888454437256,
"loss_toxic": 0.12325893342494965,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.5862068965517241,
"acc_toxic": 0.9230769230769231
},
{
"loss": 2.605057497819265,
"loss_size": 0.2653820440173149,
"loss_pdi": 0.5340018967787424,
"loss_ee": 0.7732295195261637,
"loss_delivery": 1.9833302820722263,
"loss_biodist": 0.19804245233535767,
"loss_toxic": 0.09954109663764636,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5632183908045977,
"acc_toxic": 0.9384615384615385
},
{
"loss": 2.576811154683431,
"loss_size": 0.2867562224467595,
"loss_pdi": 0.5309644540150961,
"loss_ee": 0.7620133956273397,
"loss_delivery": 1.9649020830790203,
"loss_biodist": 0.18991297980149588,
"loss_toxic": 0.10853791919847329,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5747126436781609,
"acc_toxic": 0.9384615384615385
},
{
"loss": 2.5864924987157187,
"loss_size": 0.259530708193779,
"loss_pdi": 0.5184463063875834,
"loss_ee": 0.7452393968900045,
"loss_delivery": 1.9519417062401772,
"loss_biodist": 0.22470373411973318,
"loss_toxic": 0.0957671720534563,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9384615384615385
},
{
"loss": 2.553086598714193,
"loss_size": 0.25540440529584885,
"loss_pdi": 0.5097046693166097,
"loss_ee": 0.7467661301294962,
"loss_delivery": 1.9443476051092148,
"loss_biodist": 0.20182973643143973,
"loss_toxic": 0.08854831817249458,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.499727408091227,
"loss_size": 0.26386228452126187,
"loss_pdi": 0.5052837530771891,
"loss_ee": 0.7364809711774191,
"loss_delivery": 1.8893742362658184,
"loss_biodist": 0.20716623961925507,
"loss_toxic": 0.0854283267011245,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.4599782625834146,
"loss_size": 0.26920782029628754,
"loss_pdi": 0.5060783922672272,
"loss_ee": 0.7539335886637369,
"loss_delivery": 1.840934470295906,
"loss_biodist": 0.2097578098376592,
"loss_toxic": 0.08722989726811647,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5054290890693665,
"loss_size": 0.25202465305725735,
"loss_pdi": 0.5087447861830393,
"loss_ee": 0.7526501218477885,
"loss_delivery": 1.8969171245892842,
"loss_biodist": 0.20071869591871896,
"loss_toxic": 0.08344302233308554,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6091954022988506,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.6304458578427634,
"loss_size": 0.24580197781324387,
"loss_pdi": 0.5107802053292593,
"loss_ee": 0.7400563756624857,
"loss_delivery": 2.025278240442276,
"loss_biodist": 0.2014648268620173,
"loss_toxic": 0.07743096786240737,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.58742622534434,
"loss_size": 0.23428160945574442,
"loss_pdi": 0.5037863651911417,
"loss_ee": 0.7321393291155497,
"loss_delivery": 1.9830101405580838,
"loss_biodist": 0.20580615103244781,
"loss_toxic": 0.08808133285492659,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.6505470871925354,
"loss_size": 0.2443437104423841,
"loss_pdi": 0.5023224651813507,
"loss_ee": 0.7528051336606344,
"loss_delivery": 2.043670160075029,
"loss_biodist": 0.2017277628183365,
"loss_toxic": 0.08352838673939307,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.6514063278834024,
"loss_size": 0.240423155327638,
"loss_pdi": 0.509108692407608,
"loss_ee": 0.7325820525487264,
"loss_delivery": 2.05270845691363,
"loss_biodist": 0.197861115137736,
"loss_toxic": 0.08574454641590516,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.583128869533539,
"loss_size": 0.237098495165507,
"loss_pdi": 0.5248424112796783,
"loss_ee": 0.7245094974835714,
"loss_delivery": 1.9848384857177734,
"loss_biodist": 0.19549405574798584,
"loss_toxic": 0.08561834258337815,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.6551724137931034,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5815611282984414,
"loss_size": 0.22862464686234793,
"loss_pdi": 0.5168076356252035,
"loss_ee": 0.7483010093371073,
"loss_delivery": 1.9734878987073898,
"loss_biodist": 0.20175529023011526,
"loss_toxic": 0.07845923118293285,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5652170379956565,
"loss_size": 0.22489564244945845,
"loss_pdi": 0.5051810443401337,
"loss_ee": 0.7737119396527609,
"loss_delivery": 1.9498225003480911,
"loss_biodist": 0.20508555074532828,
"loss_toxic": 0.08302718152602513,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.547056237856547,
"loss_size": 0.23514544839660326,
"loss_pdi": 0.5057700872421265,
"loss_ee": 0.7581491271654764,
"loss_delivery": 1.9406455159187317,
"loss_biodist": 0.19921203951040903,
"loss_toxic": 0.09016719833016396,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5900548497835794,
"loss_size": 0.23349140584468842,
"loss_pdi": 0.5251068969567617,
"loss_ee": 0.7729674975077311,
"loss_delivery": 1.9717801064252853,
"loss_biodist": 0.20123448967933655,
"loss_toxic": 0.08537425597508748,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.6091954022988506,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.6260739167531333,
"loss_size": 0.24243240679303804,
"loss_pdi": 0.5261660814285278,
"loss_ee": 0.7714508374532064,
"loss_delivery": 2.003963842988014,
"loss_biodist": 0.20478984216849008,
"loss_toxic": 0.07583590379605691,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.6176758805910745,
"loss_size": 0.23349024603764215,
"loss_pdi": 0.5058200458685557,
"loss_ee": 0.7715896765391032,
"loss_delivery": 1.9937649766604106,
"loss_biodist": 0.21355454126993814,
"loss_toxic": 0.07569211752464373,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5908872882525125,
"loss_size": 0.2325481710334619,
"loss_pdi": 0.49828189611434937,
"loss_ee": 0.7676852345466614,
"loss_delivery": 1.9730971604585648,
"loss_biodist": 0.21092456082503,
"loss_toxic": 0.07641367707401514,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.6206896551724138,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.575022339820862,
"loss_size": 0.23532426978151003,
"loss_pdi": 0.5039840241273245,
"loss_ee": 0.7693471312522888,
"loss_delivery": 1.9599756399790447,
"loss_biodist": 0.20553538699944815,
"loss_toxic": 0.07958741734425227,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9538461538461539
},
{
"loss": 2.5952457785606384,
"loss_size": 0.23198514183362326,
"loss_pdi": 0.5060171186923981,
"loss_ee": 0.7528701424598694,
"loss_delivery": 1.988020082314809,
"loss_biodist": 0.2024876375993093,
"loss_toxic": 0.07746962085366249,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.632183908045977,
"acc_toxic": 0.9538461538461539
}
]
}

BIN
models/finetune_cv/fold_1/loss_curves.png
View File

Binary file not shown.
Side by Side

Before

Width:  |  Height:  |  Size: 274 KiB

3
models/finetune_cv/fold_1/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:1349263a27f416eeabf3406741e970bae831dd9820e6d2a06f111c0f840d20c1
size 28583404

909
models/finetune_cv/fold_2/history.json
View File

@ -1,909 +0,0 @@
{
"train": [
{
"loss": 5.139251894421047,
"loss_size": 18.255918714735245,
"loss_pdi": 1.4547024832831488,
"loss_ee": 0.9951423605283102,
"loss_delivery": 1.369092850221528,
"loss_biodist": 1.17765031920539,
"loss_toxic": 0.6392669214142693
},
{
"loss": 3.64231096373664,
"loss_size": 10.21123472849528,
"loss_pdi": 1.240215884314643,
"loss_ee": 0.8628378576702542,
"loss_delivery": 1.0419619878133137,
"loss_biodist": 0.9237241215176053,
"loss_toxic": 0.4917045964135064
},
{
"loss": 2.7889217270745172,
"loss_size": 4.4495263364579944,
"loss_pdi": 1.0561060905456543,
"loss_ee": 0.8587031695577834,
"loss_delivery": 0.999385497222344,
"loss_biodist": 0.7524971233473884,
"loss_toxic": 0.3528722888893551
},
{
"loss": 2.2672601474656,
"loss_size": 1.4913470016585455,
"loss_pdi": 0.8523372809092203,
"loss_ee": 0.8071102499961853,
"loss_delivery": 0.9741002644101778,
"loss_biodist": 0.6308724019262526,
"loss_toxic": 0.30636945366859436
},
{
"loss": 2.022864964273241,
"loss_size": 0.6313594480355581,
"loss_pdi": 0.7438424295849271,
"loss_ee": 0.8523609373304579,
"loss_delivery": 0.91272625947992,
"loss_biodist": 0.557274106476042,
"loss_toxic": 0.21735279427634346
},
{
"loss": 1.7709284491009183,
"loss_size": 0.44420380890369415,
"loss_pdi": 0.6946110592948066,
"loss_ee": 0.81541022989485,
"loss_delivery": 0.8176283654239442,
"loss_biodist": 0.446377479367786,
"loss_toxic": 0.18991627544164658
},
{
"loss": 1.6503789623578389,
"loss_size": 0.3331033769581053,
"loss_pdi": 0.6798426508903503,
"loss_ee": 0.7439019216431512,
"loss_delivery": 0.7646371420058939,
"loss_biodist": 0.41619129644499886,
"loss_toxic": 0.1823362335562706
},
{
"loss": 1.6370787355634902,
"loss_size": 0.3876252720753352,
"loss_pdi": 0.6222998367415534,
"loss_ee": 0.7562006579505073,
"loss_delivery": 0.8021564185619354,
"loss_biodist": 0.3746331400341458,
"loss_toxic": 0.1595295642813047
},
{
"loss": 1.6646928919686212,
"loss_size": 0.31976059244738686,
"loss_pdi": 0.581528988149431,
"loss_ee": 0.7599472535981072,
"loss_delivery": 0.9176083041561974,
"loss_biodist": 0.3052833610110813,
"loss_toxic": 0.14764550452431044
},
{
"loss": 1.3619524902767606,
"loss_size": 0.35288184881210327,
"loss_pdi": 0.5895155138439603,
"loss_ee": 0.7002712421947055,
"loss_delivery": 0.6571712667743365,
"loss_biodist": 0.27557782497670913,
"loss_toxic": 0.13958367829521498
},
{
"loss": 1.3252125117513869,
"loss_size": 0.3026164356205199,
"loss_pdi": 0.5637452337476943,
"loss_ee": 0.7627982828352187,
"loss_delivery": 0.6236839824252658,
"loss_biodist": 0.2627003623379601,
"loss_toxic": 0.21206890501909786
},
{
"loss": 1.2161508136325412,
"loss_size": 0.3420029895173179,
"loss_pdi": 0.5730012555917104,
"loss_ee": 0.708204534318712,
"loss_delivery": 0.5620645673738586,
"loss_biodist": 0.2289810578028361,
"loss_toxic": 0.13086184341874388
},
{
"loss": 1.2935665713416205,
"loss_size": 0.38334204587671494,
"loss_pdi": 0.5260285569561852,
"loss_ee": 0.6511440376440684,
"loss_delivery": 0.5544850892490811,
"loss_biodist": 0.3414434674713347,
"loss_toxic": 0.12304087148772345
},
{
"loss": 5.409876909520891,
"loss_size": 0.3181511246495777,
"loss_pdi": 0.5623877512084113,
"loss_ee": 0.7138791084289551,
"loss_delivery": 4.7970883953902455,
"loss_biodist": 0.1927290881673495,
"loss_toxic": 0.10727907593051593
},
{
"loss": 1.340933746761746,
"loss_size": 0.32958291305436027,
"loss_pdi": 0.5110453930166032,
"loss_ee": 0.7083752353986105,
"loss_delivery": 0.7409339489208328,
"loss_biodist": 0.19616179002655876,
"loss_toxic": 0.10106996219191286
},
{
"loss": 1.0691162480248346,
"loss_size": 0.30996668918265236,
"loss_pdi": 0.4969583948453267,
"loss_ee": 0.6292141344812181,
"loss_delivery": 0.5027303081005812,
"loss_biodist": 0.19247801105181375,
"loss_toxic": 0.10118913650512695
},
{
"loss": 1.0167819791369967,
"loss_size": 0.3562137981255849,
"loss_pdi": 0.5296954148345523,
"loss_ee": 0.6339806550078921,
"loss_delivery": 0.45454515847894883,
"loss_biodist": 0.17251272085640165,
"loss_toxic": 0.09999801052941217
},
{
"loss": 1.0154686570167542,
"loss_size": 0.3462930570046107,
"loss_pdi": 0.49900667866071063,
"loss_ee": 0.6753647228082021,
"loss_delivery": 0.4417766301582257,
"loss_biodist": 0.18206290900707245,
"loss_toxic": 0.09376725657946533
},
{
"loss": 1.0083332525359259,
"loss_size": 0.3448386490345001,
"loss_pdi": 0.47799601819780135,
"loss_ee": 0.6449068387349447,
"loss_delivery": 0.44255588783158195,
"loss_biodist": 0.1897839763098293,
"loss_toxic": 0.09277291223406792
},
{
"loss": 2.8527750372886658,
"loss_size": 0.3211866410242187,
"loss_pdi": 0.466962241464191,
"loss_ee": 0.619562202029758,
"loss_delivery": 2.3314214969674745,
"loss_biodist": 0.15861106167236963,
"loss_toxic": 0.0933265160355303
},
{
"loss": 3.318498412768046,
"loss_size": 0.3055083437098397,
"loss_pdi": 0.508542107211219,
"loss_ee": 0.6240747703446282,
"loss_delivery": 2.7895843990974956,
"loss_biodist": 0.15397296763128704,
"loss_toxic": 0.09210634795534942
},
{
"loss": 0.918470025062561,
"loss_size": 0.2627165905303425,
"loss_pdi": 0.5129183067215813,
"loss_ee": 0.5271153483125899,
"loss_delivery": 0.4334480282333162,
"loss_biodist": 0.1417437212334739,
"loss_toxic": 0.09993022059400876
},
{
"loss": 1.0699834889835782,
"loss_size": 0.34617717067400616,
"loss_pdi": 0.4360787322123845,
"loss_ee": 0.5730780065059662,
"loss_delivery": 0.4698265939950943,
"loss_biodist": 0.2587573172317611,
"loss_toxic": 0.08069657844801743
},
{
"loss": 1.0059879289733038,
"loss_size": 0.36413417094283634,
"loss_pdi": 0.4957417415248023,
"loss_ee": 0.7273752954271104,
"loss_delivery": 0.4576577850513988,
"loss_biodist": 0.1408020613922013,
"loss_toxic": 0.08359015691611502
},
{
"loss": 0.8688187599182129,
"loss_size": 0.33713936309019726,
"loss_pdi": 0.5072802537017398,
"loss_ee": 0.5422209766176012,
"loss_delivery": 0.3248988776985142,
"loss_biodist": 0.18646930075354046,
"loss_toxic": 0.17772543616592884
},
{
"loss": 0.8379502296447754,
"loss_size": 0.2946032186349233,
"loss_pdi": 0.521089580323961,
"loss_ee": 0.5094592074553171,
"loss_delivery": 0.3478571922621793,
"loss_biodist": 0.14639283219973245,
"loss_toxic": 0.10150489293866688
},
{
"loss": 0.9374960064888,
"loss_size": 0.26913181361224914,
"loss_pdi": 0.4388515022065904,
"loss_ee": 0.6206868820720248,
"loss_delivery": 0.46183038213186794,
"loss_biodist": 0.12716854198111427,
"loss_toxic": 0.0744475541739828
},
{
"loss": 0.9113429586092631,
"loss_size": 0.25616512695948285,
"loss_pdi": 0.4470512204700046,
"loss_ee": 0.45756785074869794,
"loss_delivery": 0.4572531705101331,
"loss_biodist": 0.15281236833996242,
"loss_toxic": 0.08550410117540094
},
{
"loss": 0.8292446765634749,
"loss_size": 0.2894001031915347,
"loss_pdi": 0.4667682581477695,
"loss_ee": 0.5188069840272268,
"loss_delivery": 0.36954768415954375,
"loss_biodist": 0.131046953300635,
"loss_toxic": 0.08074895333912638
},
{
"loss": 0.6891238391399384,
"loss_size": 0.25525398386849296,
"loss_pdi": 0.46496177713076275,
"loss_ee": 0.44490377770529854,
"loss_delivery": 0.2736547390619914,
"loss_biodist": 0.11279644941290219,
"loss_toxic": 0.08375167722503345
},
{
"loss": 0.7697626617219713,
"loss_size": 0.26391809268130195,
"loss_pdi": 0.4175148374504513,
"loss_ee": 0.5703725583023496,
"loss_delivery": 0.3234751025835673,
"loss_biodist": 0.11972091678116056,
"loss_toxic": 0.07617180121855603
},
{
"loss": 0.9416903191142612,
"loss_size": 0.49958010845714146,
"loss_pdi": 0.4838709731896718,
"loss_ee": 0.4997891816827986,
"loss_delivery": 0.3387083150446415,
"loss_biodist": 0.25379470321867204,
"loss_toxic": 0.08262476035290295
},
{
"loss": 0.6869820290141635,
"loss_size": 0.21171052588356865,
"loss_pdi": 0.44965215192900765,
"loss_ee": 0.4661892420715756,
"loss_delivery": 0.2652882475198971,
"loss_biodist": 0.11738730635907915,
"loss_toxic": 0.16766001346210638
},
{
"loss": 0.6759138604005178,
"loss_size": 0.24878723836607403,
"loss_pdi": 0.45910440882047016,
"loss_ee": 0.4711561832163069,
"loss_delivery": 0.24781699437234136,
"loss_biodist": 0.11970764398574829,
"loss_toxic": 0.08864626495374574
},
{
"loss": 0.7230739792188009,
"loss_size": 0.3637457970115874,
"loss_pdi": 0.47329240706231857,
"loss_ee": 0.5751479499869876,
"loss_delivery": 0.24973291965822378,
"loss_biodist": 0.11896533767382304,
"loss_toxic": 0.0693803865255581
},
{
"loss": 0.7207142412662506,
"loss_size": 0.24164928785628742,
"loss_pdi": 0.39347541994518703,
"loss_ee": 0.4715595377816094,
"loss_delivery": 0.2935545038845804,
"loss_biodist": 0.14002070079247156,
"loss_toxic": 0.0692720040678978
},
{
"loss": 0.6264101531770494,
"loss_size": 0.22771124583151606,
"loss_pdi": 0.43112750848134357,
"loss_ee": 0.4959179725911882,
"loss_delivery": 0.21540678416689238,
"loss_biodist": 0.1060871494313081,
"loss_toxic": 0.08062908322446877
},
{
"loss": 0.6376459432972802,
"loss_size": 0.184081029974752,
"loss_pdi": 0.4103393422232734,
"loss_ee": 0.42426929871241253,
"loss_delivery": 0.2381463059120708,
"loss_biodist": 0.12710104551580217,
"loss_toxic": 0.07215786042312781
},
{
"loss": 0.6518991755114661,
"loss_size": 0.2276122487253613,
"loss_pdi": 0.38286086751355064,
"loss_ee": 0.45352989931901294,
"loss_delivery": 0.2694389389620887,
"loss_biodist": 0.10533043245474498,
"loss_toxic": 0.0690268272947934
},
{
"loss": 0.6391126778390672,
"loss_size": 0.2202053980694877,
"loss_pdi": 0.39931146303812665,
"loss_ee": 0.44839615788724685,
"loss_delivery": 0.245766029589706,
"loss_biodist": 0.11359922753440009,
"loss_toxic": 0.06829173966414398
},
{
"loss": 0.6182903978559706,
"loss_size": 0.23495068897803625,
"loss_pdi": 0.3921548028786977,
"loss_ee": 0.4279818567964766,
"loss_delivery": 0.2342767378108369,
"loss_biodist": 0.11119561394055684,
"loss_toxic": 0.06563983009093338
},
{
"loss": 0.7020416193538241,
"loss_size": 0.20867553643054432,
"loss_pdi": 0.4135015341970656,
"loss_ee": 0.5087168878979154,
"loss_delivery": 0.28151728792323005,
"loss_biodist": 0.11943934443924162,
"loss_toxic": 0.07103786348468727
},
{
"loss": 0.6722757054699792,
"loss_size": 0.26197479251358247,
"loss_pdi": 0.4025777230660121,
"loss_ee": 0.45954585406515336,
"loss_delivery": 0.22732874212993515,
"loss_biodist": 0.15652559532059562,
"loss_toxic": 0.07173617442862855
}
],
"val": [
{
"loss": 4.131735324859619,
"loss_size": 14.58691660563151,
"loss_pdi": 1.3837243715922039,
"loss_ee": 0.9805293877919515,
"loss_delivery": 0.7687161564826965,
"loss_biodist": 1.166004220644633,
"loss_toxic": 0.5809426705042521,
"acc_pdi": 0.2413793103448276,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9491525423728814
},
{
"loss": 2.9744084676106772,
"loss_size": 7.2587464650472,
"loss_pdi": 1.156416654586792,
"loss_ee": 0.9220690925916036,
"loss_delivery": 0.597048948208491,
"loss_biodist": 1.0086946686108906,
"loss_toxic": 0.3848884105682373,
"acc_pdi": 0.4827586206896552,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9491525423728814
},
{
"loss": 2.350477854410807,
"loss_size": 2.4879841009775796,
"loss_pdi": 0.9450472593307495,
"loss_ee": 0.9053510427474976,
"loss_delivery": 0.602060874303182,
"loss_biodist": 0.9306658307711283,
"loss_toxic": 0.27666471401850384,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.9528553485870361,
"loss_size": 0.6526210308074951,
"loss_pdi": 0.7912364800771078,
"loss_ee": 0.8865965604782104,
"loss_delivery": 0.5240970949331919,
"loss_biodist": 0.8494408925374349,
"loss_toxic": 0.21410620709260306,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.4762204090754192,
"loss_size": 0.3241706391175588,
"loss_pdi": 0.6979280511538187,
"loss_ee": 0.8111297488212585,
"loss_delivery": 0.37876227994759876,
"loss_biodist": 0.6028553247451782,
"loss_toxic": 0.189366581539313,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5977011494252874,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.3181473016738892,
"loss_size": 0.2733151863018672,
"loss_pdi": 0.6492085854212443,
"loss_ee": 0.7717010776201884,
"loss_delivery": 0.378572940826416,
"loss_biodist": 0.47726596395174664,
"loss_toxic": 0.17407927413781485,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.1457157135009766,
"loss_size": 0.30249467492103577,
"loss_pdi": 0.6292304197947184,
"loss_ee": 0.749643087387085,
"loss_delivery": 0.30637872715791065,
"loss_biodist": 0.38742222388585407,
"loss_toxic": 0.1600656397640705,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.0727794170379639,
"loss_size": 0.36272693673769635,
"loss_pdi": 0.6248886783917745,
"loss_ee": 0.7381813923517863,
"loss_delivery": 0.29379741350809735,
"loss_biodist": 0.32651687661806744,
"loss_toxic": 0.14542773986856142,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6551724137931034,
"acc_toxic": 0.9491525423728814
},
{
"loss": 1.0073781212170918,
"loss_size": 0.29352664947509766,
"loss_pdi": 0.609452486038208,
"loss_ee": 0.7222137649854025,
"loss_delivery": 0.2781063914299011,
"loss_biodist": 0.29349783062934875,
"loss_toxic": 0.1384266937772433,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.9849437475204468,
"loss_size": 0.3306474983692169,
"loss_pdi": 0.5996046264966329,
"loss_ee": 0.7186261018117269,
"loss_delivery": 0.28099290033181507,
"loss_biodist": 0.26886581381162006,
"loss_toxic": 0.13102031871676445,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.6436781609195402,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.9318729440371195,
"loss_size": 0.29619741439819336,
"loss_pdi": 0.590697447458903,
"loss_ee": 0.7106417814890543,
"loss_delivery": 0.26873059074083966,
"loss_biodist": 0.23739753663539886,
"loss_toxic": 0.11446575820446014,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.6551724137931034,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8952556848526001,
"loss_size": 0.375252107779185,
"loss_pdi": 0.5910165111223856,
"loss_ee": 0.7032236456871033,
"loss_delivery": 0.24763291825850806,
"loss_biodist": 0.21648145218690237,
"loss_toxic": 0.10688123355309169,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.9018304944038391,
"loss_size": 0.3556465804576874,
"loss_pdi": 0.588855524857839,
"loss_ee": 0.6812717517217001,
"loss_delivery": 0.28270446757475537,
"loss_biodist": 0.19784348209698996,
"loss_toxic": 0.09359317521254222,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.6666666666666666,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8478340109189352,
"loss_size": 0.2671582102775574,
"loss_pdi": 0.5828780929247538,
"loss_ee": 0.6747428774833679,
"loss_delivery": 0.24342622111241022,
"loss_biodist": 0.19594197471936545,
"loss_toxic": 0.08927365578711033,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8679020206133524,
"loss_size": 0.3021097580591838,
"loss_pdi": 0.5711094538370768,
"loss_ee": 0.6691598693529764,
"loss_delivery": 0.2682334979375203,
"loss_biodist": 0.19272477428118387,
"loss_toxic": 0.09303904076417287,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8528247078259786,
"loss_size": 0.3143278906742732,
"loss_pdi": 0.569633682568868,
"loss_ee": 0.6673540075620016,
"loss_delivery": 0.2597464472055435,
"loss_biodist": 0.18668038149674734,
"loss_toxic": 0.07737583356599013,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8371174534161886,
"loss_size": 0.3687616139650345,
"loss_pdi": 0.5657906929651896,
"loss_ee": 0.6549434860547384,
"loss_delivery": 0.2737381011247635,
"loss_biodist": 0.15673434734344482,
"loss_toxic": 0.07097066317995389,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.9556880990664164,
"loss_size": 0.44675949215888977,
"loss_pdi": 0.5660895109176636,
"loss_ee": 0.6585590243339539,
"loss_delivery": 0.38440535465876263,
"loss_biodist": 0.15525126457214355,
"loss_toxic": 0.07921982059876125,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8195796807607015,
"loss_size": 0.3921011785666148,
"loss_pdi": 0.5631354848543803,
"loss_ee": 0.6436604261398315,
"loss_delivery": 0.2659662241737048,
"loss_biodist": 0.14899534980456033,
"loss_toxic": 0.06738407785693805,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8000527421633402,
"loss_size": 0.2305989811817805,
"loss_pdi": 0.5579631725947062,
"loss_ee": 0.6551848649978638,
"loss_delivery": 0.2595013752579689,
"loss_biodist": 0.15009809533754984,
"loss_toxic": 0.06897837482392788,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8249319394429525,
"loss_size": 0.2866029640038808,
"loss_pdi": 0.5442510843276978,
"loss_ee": 0.647416353225708,
"loss_delivery": 0.2793256988128026,
"loss_biodist": 0.15630457053581873,
"loss_toxic": 0.06282178312540054,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9661016949152542
},
{
"loss": 0.8143559694290161,
"loss_size": 0.3335455060005188,
"loss_pdi": 0.5397896965344747,
"loss_ee": 0.6453800797462463,
"loss_delivery": 0.2666936169068019,
"loss_biodist": 0.1549653857946396,
"loss_toxic": 0.07582870249946912,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8639025092124939,
"loss_size": 0.34606138865152997,
"loss_pdi": 0.5520124038060507,
"loss_ee": 0.6531140605608622,
"loss_delivery": 0.31263314187526703,
"loss_biodist": 0.1517741580804189,
"loss_toxic": 0.06702199609329303,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8694897691408793,
"loss_size": 0.3858671685059865,
"loss_pdi": 0.5633923411369324,
"loss_ee": 0.651544431845347,
"loss_delivery": 0.3061240514119466,
"loss_biodist": 0.1569272701938947,
"loss_toxic": 0.06741394475102425,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9661016949152542
},
{
"loss": 0.8287400603294373,
"loss_size": 0.3009648422400157,
"loss_pdi": 0.5510913133621216,
"loss_ee": 0.6359622081120809,
"loss_delivery": 0.2914886424938838,
"loss_biodist": 0.14768950392802557,
"loss_toxic": 0.06698716431856155,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8641846577326456,
"loss_size": 0.2882275680700938,
"loss_pdi": 0.5606249769528707,
"loss_ee": 0.6550668875376383,
"loss_delivery": 0.3229534278313319,
"loss_biodist": 0.14468475927909216,
"loss_toxic": 0.06032268796116114,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9491525423728814
},
{
"loss": 0.8457841674486796,
"loss_size": 0.3051060636838277,
"loss_pdi": 0.5792184869448344,
"loss_ee": 0.6697730223337809,
"loss_delivery": 0.2924912025531133,
"loss_biodist": 0.14528409391641617,
"loss_toxic": 0.056016006196538605,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.6781609195402298,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.7660132050514221,
"loss_size": 0.3071767787138621,
"loss_pdi": 0.5772291322549185,
"loss_ee": 0.6593808730443319,
"loss_delivery": 0.2261704777677854,
"loss_biodist": 0.13535468031962714,
"loss_toxic": 0.055746594443917274,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8026491602261862,
"loss_size": 0.3231980999310811,
"loss_pdi": 0.5754439433415731,
"loss_ee": 0.6595458984375,
"loss_delivery": 0.26338759809732437,
"loss_biodist": 0.13391770174105963,
"loss_toxic": 0.05054261535406113,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8309550285339355,
"loss_size": 0.3204752405484517,
"loss_pdi": 0.5751846432685852,
"loss_ee": 0.6648860772450765,
"loss_delivery": 0.29200898110866547,
"loss_biodist": 0.13234147429466248,
"loss_toxic": 0.0507163122917215,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.735632183908046,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8174562255541483,
"loss_size": 0.30330435434977215,
"loss_pdi": 0.5740452607472738,
"loss_ee": 0.6525847713152567,
"loss_delivery": 0.27965304503838223,
"loss_biodist": 0.13697389513254166,
"loss_toxic": 0.050196846636633076,
"acc_pdi": 0.7701149425287356,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.835791269938151,
"loss_size": 0.319806436697642,
"loss_pdi": 0.5706671675046285,
"loss_ee": 0.644251803557078,
"loss_delivery": 0.29097796479860943,
"loss_biodist": 0.1456004058321317,
"loss_toxic": 0.055130545515567064,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.820733646551768,
"loss_size": 0.3628026247024536,
"loss_pdi": 0.5727978746096293,
"loss_ee": 0.6543296972910563,
"loss_delivery": 0.27494684358437854,
"loss_biodist": 0.13881322741508484,
"loss_toxic": 0.051099950758119426,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.773014227549235,
"loss_size": 0.3434345026810964,
"loss_pdi": 0.5632649262746176,
"loss_ee": 0.6523848176002502,
"loss_delivery": 0.23294466733932495,
"loss_biodist": 0.13855831076701483,
"loss_toxic": 0.04945786762982607,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.6896551724137931,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.7905398408571879,
"loss_size": 0.32612042625745136,
"loss_pdi": 0.5663766860961914,
"loss_ee": 0.6568204363187155,
"loss_delivery": 0.24841550489266714,
"loss_biodist": 0.13999874889850616,
"loss_toxic": 0.05108769020686547,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.815334141254425,
"loss_size": 0.31307806571324664,
"loss_pdi": 0.5712296466032664,
"loss_ee": 0.6713330944379171,
"loss_delivery": 0.26960306614637375,
"loss_biodist": 0.1390355403224627,
"loss_toxic": 0.05237791873514652,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8541495203971863,
"loss_size": 0.33989472190539044,
"loss_pdi": 0.5753623445828756,
"loss_ee": 0.6674774487813314,
"loss_delivery": 0.3071880266070366,
"loss_biodist": 0.1377902328968048,
"loss_toxic": 0.046596549140910305,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.7011494252873564,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8057891329129537,
"loss_size": 0.35634806752204895,
"loss_pdi": 0.5825925668080648,
"loss_ee": 0.65397047996521,
"loss_delivery": 0.25933516025543213,
"loss_biodist": 0.13771875202655792,
"loss_toxic": 0.04263027384877205,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.7832738161087036,
"loss_size": 0.3584498365720113,
"loss_pdi": 0.5802697340647379,
"loss_ee": 0.6541342735290527,
"loss_delivery": 0.23583254466454187,
"loss_biodist": 0.13910961151123047,
"loss_toxic": 0.04330934304744005,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.7241379310344828,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.7725691199302673,
"loss_size": 0.3525932828585307,
"loss_pdi": 0.5890609423319498,
"loss_ee": 0.656381090482076,
"loss_delivery": 0.2219469373424848,
"loss_biodist": 0.1395219142238299,
"loss_toxic": 0.04416632062445084,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8066536982854208,
"loss_size": 0.33613314231236774,
"loss_pdi": 0.5896864136060079,
"loss_ee": 0.6661185820897421,
"loss_delivery": 0.25459036976099014,
"loss_biodist": 0.13937962551911673,
"loss_toxic": 0.046577442126969494,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8199006716410319,
"loss_size": 0.3178228735923767,
"loss_pdi": 0.5847668051719666,
"loss_ee": 0.6776002049446106,
"loss_delivery": 0.26491835216681164,
"loss_biodist": 0.14207524806261063,
"loss_toxic": 0.04829352038602034,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
},
{
"loss": 0.8241792519887289,
"loss_size": 0.32641319433848065,
"loss_pdi": 0.586793859799703,
"loss_ee": 0.675977905591329,
"loss_delivery": 0.2662969057758649,
"loss_biodist": 0.14402199536561966,
"loss_toxic": 0.04774974503864845,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.7126436781609196,
"acc_toxic": 0.9830508474576272
}
]
}

BIN
models/finetune_cv/fold_2/loss_curves.png
View File

Binary file not shown.
Side by Side

Before

Width:  |  Height:  |  Size: 274 KiB

3
models/finetune_cv/fold_2/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:60b6fb7ce69203b3954f812de76fb7c3c3801e1ee93a07d5e4f75a0a921265d6
size 28583404

657
models/finetune_cv/fold_3/history.json
View File

@ -1,657 +0,0 @@
{
"train": [
{
"loss": 4.766850815878974,
"loss_size": 15.63866795433892,
"loss_pdi": 1.4077769782808092,
"loss_ee": 1.0127089752091303,
"loss_delivery": 1.3605128940608766,
"loss_biodist": 1.0889521506097581,
"loss_toxic": 0.5474630693594614
},
{
"loss": 3.194937891430325,
"loss_size": 7.066763983832465,
"loss_pdi": 1.2058304680718317,
"loss_ee": 0.9401931100421481,
"loss_delivery": 0.9668611710270246,
"loss_biodist": 0.8577001161045499,
"loss_toxic": 0.39786019259028965
},
{
"loss": 2.46968854798211,
"loss_size": 2.020951430002848,
"loss_pdi": 0.9755231804317899,
"loss_ee": 0.8675648834970262,
"loss_delivery": 1.0441547433535259,
"loss_biodist": 0.6567856768767039,
"loss_toxic": 0.2745304654041926
},
{
"loss": 1.9164424075020685,
"loss_size": 0.68251081638866,
"loss_pdi": 0.7992922133869595,
"loss_ee": 0.8658047715822855,
"loss_delivery": 0.8073295288615756,
"loss_biodist": 0.5298031899664137,
"loss_toxic": 0.23059075905217064
},
{
"loss": 2.118057608604431,
"loss_size": 0.4456057962444093,
"loss_pdi": 0.6909500625398424,
"loss_ee": 0.8241950538423326,
"loss_delivery": 1.1301221292879846,
"loss_biodist": 0.4791218439737956,
"loss_toxic": 0.194189776149061
},
{
"loss": 1.6527547637621562,
"loss_size": 0.5215758283933004,
"loss_pdi": 0.6607316335042318,
"loss_ee": 0.8006990419493781,
"loss_delivery": 0.7876643521918191,
"loss_biodist": 0.3641456299357944,
"loss_toxic": 0.20715977665450838
},
{
"loss": 1.5360244909922283,
"loss_size": 0.5412709133492576,
"loss_pdi": 0.6476934783988528,
"loss_ee": 0.8275714185502794,
"loss_delivery": 0.7246163586775461,
"loss_biodist": 0.30502668850951725,
"loss_toxic": 0.19349763542413712
},
{
"loss": 1.5586009290483263,
"loss_size": 0.3165152288145489,
"loss_pdi": 0.5958941512637668,
"loss_ee": 0.7949910230106778,
"loss_delivery": 0.7548645718230141,
"loss_biodist": 0.3413304222954644,
"loss_toxic": 0.2697768459717433
},
{
"loss": 1.333560003174676,
"loss_size": 0.3286761086848047,
"loss_pdi": 0.5951504939132266,
"loss_ee": 0.725921803050571,
"loss_delivery": 0.6468726520737013,
"loss_biodist": 0.25011805362171596,
"loss_toxic": 0.14759980224900776
},
{
"loss": 1.255424247847663,
"loss_size": 0.29291238139073056,
"loss_pdi": 0.5680392252074348,
"loss_ee": 0.7574183543523153,
"loss_delivery": 0.6383567195799615,
"loss_biodist": 0.18393014868100485,
"loss_toxic": 0.12417802256014612
},
{
"loss": 1.2708108557595148,
"loss_size": 0.31006419989797807,
"loss_pdi": 0.5562698278162215,
"loss_ee": 0.7223905060026381,
"loss_delivery": 0.664460855225722,
"loss_biodist": 0.18582438594765133,
"loss_toxic": 0.11842195689678192
},
{
"loss": 1.156555347972446,
"loss_size": 0.3705143613947762,
"loss_pdi": 0.5945881505807241,
"loss_ee": 0.6829384366671244,
"loss_delivery": 0.5518036550945706,
"loss_biodist": 0.17766478988859388,
"loss_toxic": 0.13554949147833717
},
{
"loss": 1.2082195546891954,
"loss_size": 0.3124586840470632,
"loss_pdi": 0.5598477522532145,
"loss_ee": 0.7115180227491591,
"loss_delivery": 0.5732465990715556,
"loss_biodist": 0.21678477277358374,
"loss_toxic": 0.11065146616763538
},
{
"loss": 1.102220508787367,
"loss_size": 0.3106573008828693,
"loss_pdi": 0.5404789878262414,
"loss_ee": 0.6773724357287089,
"loss_delivery": 0.5458149686455727,
"loss_biodist": 0.15416353775395286,
"loss_toxic": 0.11641708016395569
},
{
"loss": 1.043630109892951,
"loss_size": 0.2982923752731747,
"loss_pdi": 0.5440624621179369,
"loss_ee": 0.6503448751237657,
"loss_delivery": 0.49866140882174176,
"loss_biodist": 0.1519940048456192,
"loss_toxic": 0.0964651687277688
},
{
"loss": 0.9901837706565857,
"loss_size": 0.32042061785856885,
"loss_pdi": 0.5456168519126045,
"loss_ee": 0.6092376344733768,
"loss_delivery": 0.4618735123011801,
"loss_biodist": 0.14514495349592632,
"loss_toxic": 0.09333733800384733
},
{
"loss": 0.9261764619085524,
"loss_size": 0.2747669534550773,
"loss_pdi": 0.46863247950871784,
"loss_ee": 0.6223281655046675,
"loss_delivery": 0.43099362154801685,
"loss_biodist": 0.13571486870447794,
"loss_toxic": 0.09406161163416174
},
{
"loss": 0.9039155642191569,
"loss_size": 0.2712312920225991,
"loss_pdi": 0.4773247606224484,
"loss_ee": 0.6943600740697649,
"loss_delivery": 0.3650132914384206,
"loss_biodist": 0.1541641346282429,
"loss_toxic": 0.12219080411725575
},
{
"loss": 0.9223330484496223,
"loss_size": 0.2766229725546307,
"loss_pdi": 0.5800718201531304,
"loss_ee": 0.6270876063240899,
"loss_delivery": 0.392147966971,
"loss_biodist": 0.13427263995011648,
"loss_toxic": 0.12204609811306
},
{
"loss": 0.9236893885665469,
"loss_size": 0.3107699404160182,
"loss_pdi": 0.4369298302465015,
"loss_ee": 0.5817281405131022,
"loss_delivery": 0.4464465623928441,
"loss_biodist": 0.13595506134960386,
"loss_toxic": 0.09226770264406998
},
{
"loss": 0.8442953030268351,
"loss_size": 0.3012015488412645,
"loss_pdi": 0.4543476899464925,
"loss_ee": 0.6064623528056674,
"loss_delivery": 0.3622342257036103,
"loss_biodist": 0.1288523781630728,
"loss_toxic": 0.09691004972490999
},
{
"loss": 0.8079752839273877,
"loss_size": 0.22200237876839107,
"loss_pdi": 0.4342757264773051,
"loss_ee": 0.5310212539301978,
"loss_delivery": 0.38058414599961704,
"loss_biodist": 0.11056508041090435,
"loss_toxic": 0.10073411464691162
},
{
"loss": 0.8152433236440023,
"loss_size": 0.27602333575487137,
"loss_pdi": 0.4640119738048977,
"loss_ee": 0.584001213312149,
"loss_delivery": 0.35978588047954774,
"loss_biodist": 0.109148475031058,
"loss_toxic": 0.08605334328280555
},
{
"loss": 0.7466643585099114,
"loss_size": 0.24374761349625057,
"loss_pdi": 0.4308427737818824,
"loss_ee": 0.5365780227714114,
"loss_delivery": 0.3153134650654263,
"loss_biodist": 0.11251256283786562,
"loss_toxic": 0.08474667732500368
},
{
"loss": 0.7341683738761478,
"loss_size": 0.2687344468302197,
"loss_pdi": 0.4049629403485192,
"loss_ee": 0.550721804300944,
"loss_delivery": 0.31168443544043434,
"loss_biodist": 0.10471605840656492,
"loss_toxic": 0.08378015996681319
},
{
"loss": 0.7389170328776041,
"loss_size": 0.2217162922024727,
"loss_pdi": 0.41024701793988544,
"loss_ee": 0.5442798535029093,
"loss_delivery": 0.32037310529914165,
"loss_biodist": 0.1062177527281973,
"loss_toxic": 0.07592944800853729
},
{
"loss": 0.9186691045761108,
"loss_size": 0.2542582510246171,
"loss_pdi": 0.4154413806067573,
"loss_ee": 0.5430747667948405,
"loss_delivery": 0.4891529091530376,
"loss_biodist": 0.11287814461522633,
"loss_toxic": 0.0731476778164506
},
{
"loss": 0.6999551819430457,
"loss_size": 0.23464642216761908,
"loss_pdi": 0.4029058383570777,
"loss_ee": 0.517158031463623,
"loss_delivery": 0.2912305270632108,
"loss_biodist": 0.10445927911334568,
"loss_toxic": 0.0956310552234451
},
{
"loss": 0.7278001209100088,
"loss_size": 0.19584539035956064,
"loss_pdi": 0.4052301281028324,
"loss_ee": 0.4991186757882436,
"loss_delivery": 0.3293461489180724,
"loss_biodist": 0.10376342799928454,
"loss_toxic": 0.0760267341716422
},
{
"loss": 0.683016277021832,
"loss_size": 0.24779578877819908,
"loss_pdi": 0.42786730494764114,
"loss_ee": 0.4919361074765523,
"loss_delivery": 0.27164340474539334,
"loss_biodist": 0.10706264277299245,
"loss_toxic": 0.07179253765692313
},
{
"loss": 0.7323974437183804,
"loss_size": 0.22115148852268854,
"loss_pdi": 0.4249776038858626,
"loss_ee": 0.4751305017206404,
"loss_delivery": 0.3237520249353515,
"loss_biodist": 0.11182647032870187,
"loss_toxic": 0.09342663404014376
}
],
"val": [
{
"loss": 3.561950127283732,
"loss_size": 10.067278861999512,
"loss_pdi": 1.2844754457473755,
"loss_ee": 1.022406319777171,
"loss_delivery": 0.807799776395162,
"loss_biodist": 1.035092035929362,
"loss_toxic": 0.40531662106513977,
"acc_pdi": 0.3103448275862069,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 2.5210230350494385,
"loss_size": 2.8152450720469155,
"loss_pdi": 1.0565770467122395,
"loss_ee": 1.0103971759478252,
"loss_delivery": 0.7065088053544363,
"loss_biodist": 0.9002302885055542,
"loss_toxic": 0.2533448139826457,
"acc_pdi": 0.632183908045977,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 2.1147218545277915,
"loss_size": 0.5404441356658936,
"loss_pdi": 0.8330013354619344,
"loss_ee": 1.0115772883097331,
"loss_delivery": 0.6684561967849731,
"loss_biodist": 0.8304030299186707,
"loss_toxic": 0.168889249364535,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.8772199948628743,
"loss_size": 0.36127155522505444,
"loss_pdi": 0.7154155373573303,
"loss_ee": 1.012442131837209,
"loss_delivery": 0.6113372246424357,
"loss_biodist": 0.7049875855445862,
"loss_toxic": 0.12821413824955621,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.8122390906016033,
"loss_size": 0.40227536857128143,
"loss_pdi": 0.6637236475944519,
"loss_ee": 0.9933545589447021,
"loss_delivery": 0.721953809261322,
"loss_biodist": 0.5474076171716055,
"loss_toxic": 0.11053389807542165,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.4150850375493367,
"loss_size": 0.40261948605378467,
"loss_pdi": 0.6394631862640381,
"loss_ee": 0.9741678237915039,
"loss_delivery": 0.4643038511276245,
"loss_biodist": 0.4214627146720886,
"loss_toxic": 0.09934474031130473,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5402298850574713,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.387380838394165,
"loss_size": 0.44533513486385345,
"loss_pdi": 0.6072933077812195,
"loss_ee": 0.9744000633557638,
"loss_delivery": 0.4964369436105092,
"loss_biodist": 0.36785226066907245,
"loss_toxic": 0.08100219070911407,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.2802993059158325,
"loss_size": 0.4120834817488988,
"loss_pdi": 0.5965191125869751,
"loss_ee": 0.9781891107559204,
"loss_delivery": 0.43886900941530865,
"loss_biodist": 0.32411964734395343,
"loss_toxic": 0.07379709059993426,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5287356321839081,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.2266828219095867,
"loss_size": 0.38946660111347836,
"loss_pdi": 0.5873191952705383,
"loss_ee": 0.95221346616745,
"loss_delivery": 0.4270549962917964,
"loss_biodist": 0.2950956126054128,
"loss_toxic": 0.07451402892669041,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5172413793103449,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.185796598593394,
"loss_size": 0.3839819207787514,
"loss_pdi": 0.5671538710594177,
"loss_ee": 0.9373603264490763,
"loss_delivery": 0.4151970644791921,
"loss_biodist": 0.27769336601098377,
"loss_toxic": 0.06307439381877582,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5747126436781609,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.1841800411542256,
"loss_size": 0.39799439410368603,
"loss_pdi": 0.5605624516805013,
"loss_ee": 0.9426294565200806,
"loss_delivery": 0.3889467219511668,
"loss_biodist": 0.30094200372695923,
"loss_toxic": 0.07068478316068649,
"acc_pdi": 0.7586206896551724,
"acc_ee": 0.5632183908045977,
"acc_toxic": 0.9672131147540983
},
{
"loss": 1.1247423489888508,
"loss_size": 0.3858395094672839,
"loss_pdi": 0.5433903634548187,
"loss_ee": 0.9457400639851888,
"loss_delivery": 0.3608016024033229,
"loss_biodist": 0.27572375535964966,
"loss_toxic": 0.05787785413364569,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.5862068965517241,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.1301468014717102,
"loss_size": 0.3769284635782242,
"loss_pdi": 0.546830435593923,
"loss_ee": 0.9560129443804423,
"loss_delivery": 0.379766305287679,
"loss_biodist": 0.2592528412739436,
"loss_toxic": 0.05163612216711044,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.5747126436781609,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.1260559558868408,
"loss_size": 0.3439995547135671,
"loss_pdi": 0.5542623599370321,
"loss_ee": 0.9629738926887512,
"loss_delivery": 0.36021967232227325,
"loss_biodist": 0.2736365447441737,
"loss_toxic": 0.05257795378565788,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.5862068965517241,
"acc_toxic": 1.0
},
{
"loss": 1.1332953373591106,
"loss_size": 0.34356490274270374,
"loss_pdi": 0.5483515659968058,
"loss_ee": 0.969600518544515,
"loss_delivery": 0.3714982221523921,
"loss_biodist": 0.26956652601559955,
"loss_toxic": 0.049768892427285515,
"acc_pdi": 0.7816091954022989,
"acc_ee": 0.5517241379310345,
"acc_toxic": 1.0
},
{
"loss": 1.065057098865509,
"loss_size": 0.34088046848773956,
"loss_pdi": 0.543300728003184,
"loss_ee": 0.9619107445081075,
"loss_delivery": 0.33130598068237305,
"loss_biodist": 0.24586749573548636,
"loss_toxic": 0.04464263655245304,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5057471264367817,
"acc_toxic": 1.0
},
{
"loss": 1.099883755048116,
"loss_size": 0.3703552732865016,
"loss_pdi": 0.5528093973795573,
"loss_ee": 0.9591174920399984,
"loss_delivery": 0.3233179847399394,
"loss_biodist": 0.28331542015075684,
"loss_toxic": 0.05273408815264702,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5517241379310345,
"acc_toxic": 1.0
},
{
"loss": 1.1591133276621501,
"loss_size": 0.35293619334697723,
"loss_pdi": 0.5591007073720297,
"loss_ee": 0.9917198816935221,
"loss_delivery": 0.3866804490486781,
"loss_biodist": 0.26972859104474384,
"loss_toxic": 0.04328965333600839,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5402298850574713,
"acc_toxic": 1.0
},
{
"loss": 1.1123783191045125,
"loss_size": 0.36454230546951294,
"loss_pdi": 0.5321346819400787,
"loss_ee": 0.9892945289611816,
"loss_delivery": 0.3702229708433151,
"loss_biodist": 0.24756573140621185,
"loss_toxic": 0.03413235923896233,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5632183908045977,
"acc_toxic": 1.0
},
{
"loss": 1.133519212404887,
"loss_size": 0.3528430064519246,
"loss_pdi": 0.5496991276741028,
"loss_ee": 0.9847154418627421,
"loss_delivery": 0.37601343790690106,
"loss_biodist": 0.2602074146270752,
"loss_toxic": 0.03379305607328812,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5747126436781609,
"acc_toxic": 1.0
},
{
"loss": 1.1322218179702759,
"loss_size": 0.3625878691673279,
"loss_pdi": 0.5723596811294556,
"loss_ee": 0.9898288249969482,
"loss_delivery": 0.3654462993144989,
"loss_biodist": 0.25969235599040985,
"loss_toxic": 0.043356820940971375,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.5632183908045977,
"acc_toxic": 0.9836065573770492
},
{
"loss": 1.1295897364616394,
"loss_size": 0.33988160888353985,
"loss_pdi": 0.5685086448987325,
"loss_ee": 1.0111762483914692,
"loss_delivery": 0.3536634296178818,
"loss_biodist": 0.2662135312954585,
"loss_toxic": 0.036381964882214866,
"acc_pdi": 0.7471264367816092,
"acc_ee": 0.5632183908045977,
"acc_toxic": 1.0
},
{
"loss": 1.1331542531649272,
"loss_size": 0.3517817209164302,
"loss_pdi": 0.5804282824198405,
"loss_ee": 1.0268070697784424,
"loss_delivery": 0.34668805698553723,
"loss_biodist": 0.2673729509115219,
"loss_toxic": 0.0348890811825792,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5402298850574713,
"acc_toxic": 1.0
},
{
"loss": 1.1203075249989827,
"loss_size": 0.3547391692797343,
"loss_pdi": 0.5759254495302836,
"loss_ee": 1.010263462861379,
"loss_delivery": 0.3434928059577942,
"loss_biodist": 0.26365240414937335,
"loss_toxic": 0.03663435267905394,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5747126436781609,
"acc_toxic": 1.0
},
{
"loss": 1.1263186136881511,
"loss_size": 0.3492508182922999,
"loss_pdi": 0.570879598458608,
"loss_ee": 1.031551678975423,
"loss_delivery": 0.3473098923762639,
"loss_biodist": 0.2615460952123006,
"loss_toxic": 0.036163472260038056,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5632183908045977,
"acc_toxic": 1.0
},
{
"loss": 1.143399755160014,
"loss_size": 0.3437139391899109,
"loss_pdi": 0.5747936765352885,
"loss_ee": 1.0320517619450886,
"loss_delivery": 0.3668489158153534,
"loss_biodist": 0.25858721137046814,
"loss_toxic": 0.030771405746539433,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5862068965517241,
"acc_toxic": 1.0
},
{
"loss": 1.1194483836491902,
"loss_size": 0.3414934227863948,
"loss_pdi": 0.5611239671707153,
"loss_ee": 1.0080342094103496,
"loss_delivery": 0.3561711361010869,
"loss_biodist": 0.25692955652872723,
"loss_toxic": 0.029017317729691666,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5862068965517241,
"acc_toxic": 1.0
},
{
"loss": 1.1253482898076375,
"loss_size": 0.32774630685647327,
"loss_pdi": 0.5613537033398946,
"loss_ee": 1.0111759305000305,
"loss_delivery": 0.3634338577588399,
"loss_biodist": 0.2559479773044586,
"loss_toxic": 0.02865783714999755,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5977011494252874,
"acc_toxic": 1.0
},
{
"loss": 1.1341807047526042,
"loss_size": 0.3308061361312866,
"loss_pdi": 0.5784129500389099,
"loss_ee": 1.0226020216941833,
"loss_delivery": 0.36487700045108795,
"loss_biodist": 0.25445938607056934,
"loss_toxic": 0.029183488028744858,
"acc_pdi": 0.7126436781609196,
"acc_ee": 0.5862068965517241,
"acc_toxic": 1.0
},
{
"loss": 1.1452271143595378,
"loss_size": 0.3295171509186427,
"loss_pdi": 0.5855477054913839,
"loss_ee": 1.031602402528127,
"loss_delivery": 0.3737790534893672,
"loss_biodist": 0.251778448621432,
"loss_toxic": 0.031455936220784984,
"acc_pdi": 0.735632183908046,
"acc_ee": 0.5747126436781609,
"acc_toxic": 1.0
},
{
"loss": 1.1348093350728352,
"loss_size": 0.3234872718652089,
"loss_pdi": 0.5850692391395569,
"loss_ee": 1.0421364903450012,
"loss_delivery": 0.3666497965653737,
"loss_biodist": 0.24612020452817282,
"loss_toxic": 0.03057790609697501,
"acc_pdi": 0.7241379310344828,
"acc_ee": 0.5862068965517241,
"acc_toxic": 1.0
}
]
}

BIN
models/finetune_cv/fold_3/loss_curves.png
View File

Binary file not shown.
Side by Side

Before

Width:  |  Height:  |  Size: 270 KiB

3
models/finetune_cv/fold_3/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:4b7dd93f4fe12bd8693471ae0e56373df05d45841c4d624a70b3a7e279c7df9f
size 28583404

762
models/finetune_cv/fold_4/history.json
View File

@ -1,762 +0,0 @@
{
"train": [
{
"loss": 4.665179676479763,
"loss_size": 16.483679241604275,
"loss_pdi": 1.3651591406928167,
"loss_ee": 1.0196819967693753,
"loss_delivery": 1.0868739096654787,
"loss_biodist": 1.1760065621799893,
"loss_toxic": 0.7695784370104471
},
{
"loss": 3.3264882034725614,
"loss_size": 7.6369165314568415,
"loss_pdi": 1.1293813917371962,
"loss_ee": 0.9773869713147482,
"loss_delivery": 0.9970956345399221,
"loss_biodist": 0.9063295192188687,
"loss_toxic": 0.5468163589636484
},
{
"loss": 2.2753378285302057,
"loss_size": 2.3639874988132052,
"loss_pdi": 0.879461043410831,
"loss_ee": 0.8743912312719557,
"loss_delivery": 0.7939755883481767,
"loss_biodist": 0.6996937460369534,
"loss_toxic": 0.38228171401553684
},
{
"loss": 1.9742275608910456,
"loss_size": 0.8084816767109765,
"loss_pdi": 0.7687598003281487,
"loss_ee": 0.8828673428959317,
"loss_delivery": 0.8191214129328728,
"loss_biodist": 0.5664933158291711,
"loss_toxic": 0.24553058048089346
},
{
"loss": 1.70375833246443,
"loss_size": 0.5723301420609156,
"loss_pdi": 0.6770902540948656,
"loss_ee": 0.853792044851515,
"loss_delivery": 0.7016346222824521,
"loss_biodist": 0.47304899824990165,
"loss_toxic": 0.2515414026048448
},
{
"loss": 1.5389259258906047,
"loss_size": 0.5172689192824893,
"loss_pdi": 0.6648565861913893,
"loss_ee": 0.8024858501222398,
"loss_delivery": 0.6659023463726044,
"loss_biodist": 0.3723145127296448,
"loss_toxic": 0.17558787183629143
},
{
"loss": 1.379139330652025,
"loss_size": 0.4229068168335491,
"loss_pdi": 0.6211051742235819,
"loss_ee": 0.8200742072529263,
"loss_delivery": 0.5743031906377938,
"loss_biodist": 0.3225533366203308,
"loss_toxic": 0.15276703155703014
},
{
"loss": 1.3731217914157443,
"loss_size": 0.3421256293853124,
"loss_pdi": 0.6012878119945526,
"loss_ee": 0.7933250202072991,
"loss_delivery": 0.6063986155721877,
"loss_biodist": 0.3042996045615938,
"loss_toxic": 0.19654365256428719
},
{
"loss": 1.3568492531776428,
"loss_size": 0.41718313097953796,
"loss_pdi": 0.5708919631110297,
"loss_ee": 0.8120904299947951,
"loss_delivery": 0.5863582235243585,
"loss_biodist": 0.30760296020242905,
"loss_toxic": 0.125500141746468
},
{
"loss": 1.1534934706158109,
"loss_size": 0.436789827214347,
"loss_pdi": 0.5596825149324205,
"loss_ee": 0.784645140171051,
"loss_delivery": 0.4494641046557162,
"loss_biodist": 0.25072355733977425,
"loss_toxic": 0.12657132041123179
},
{
"loss": 1.1161713070339627,
"loss_size": 0.35228123929765487,
"loss_pdi": 0.5342482030391693,
"loss_ee": 0.7896602352460226,
"loss_delivery": 0.46950938180088997,
"loss_biodist": 0.20850154757499695,
"loss_toxic": 0.11519382645686467
},
{
"loss": 1.0508538285891216,
"loss_size": 0.3722365266746945,
"loss_pdi": 0.5374061829513974,
"loss_ee": 0.7603495584593879,
"loss_delivery": 0.4093071048458417,
"loss_biodist": 0.2106675704320272,
"loss_toxic": 0.08657475540207492
},
{
"loss": 0.9843368728955587,
"loss_size": 0.4122349222501119,
"loss_pdi": 0.5196765396330092,
"loss_ee": 0.7339764104949104,
"loss_delivery": 0.3725525331166055,
"loss_biodist": 0.19046947525607216,
"loss_toxic": 0.07990999644001325
},
{
"loss": 0.9590536024835374,
"loss_size": 0.3655582004123264,
"loss_pdi": 0.5194678637716506,
"loss_ee": 0.74338432153066,
"loss_delivery": 0.36815490904781556,
"loss_biodist": 0.1714633653561274,
"loss_toxic": 0.08047700011067921
},
{
"loss": 0.9580893052948846,
"loss_size": 0.33270423776573604,
"loss_pdi": 0.4866763684484694,
"loss_ee": 0.7496301399336921,
"loss_delivery": 0.3872053821881612,
"loss_biodist": 0.16275441149870554,
"loss_toxic": 0.07934267508486907
},
{
"loss": 0.9246225555737814,
"loss_size": 0.31739001472791034,
"loss_pdi": 0.478587978416019,
"loss_ee": 0.7281280755996704,
"loss_delivery": 0.3336459795633952,
"loss_biodist": 0.1931910655564732,
"loss_toxic": 0.08063347472084893
},
{
"loss": 0.9282163944509294,
"loss_size": 0.4007752123806212,
"loss_pdi": 0.46156320306989884,
"loss_ee": 0.7107023662990994,
"loss_delivery": 0.37243153237634236,
"loss_biodist": 0.16070580234130225,
"loss_toxic": 0.06643716815031236
},
{
"loss": 0.833967473771837,
"loss_size": 0.36212436523702407,
"loss_pdi": 0.46506667137145996,
"loss_ee": 0.6513339082400004,
"loss_delivery": 0.2898665225754182,
"loss_biodist": 0.16712255444791582,
"loss_toxic": 0.11691546688477199
},
{
"loss": 0.9205137491226196,
"loss_size": 0.3010892520348231,
"loss_pdi": 0.4417586889531877,
"loss_ee": 0.6994220614433289,
"loss_delivery": 0.41149862565928036,
"loss_biodist": 0.13318718638685015,
"loss_toxic": 0.06729430270691712
},
{
"loss": 0.8571168449189928,
"loss_size": 0.33968671494060093,
"loss_pdi": 0.4478498631053501,
"loss_ee": 0.6466105845239427,
"loss_delivery": 0.33214224212699467,
"loss_biodist": 0.15857023745775223,
"loss_toxic": 0.08195124038805564
},
{
"loss": 0.8320284684499105,
"loss_size": 0.3630012116498417,
"loss_pdi": 0.4764490955405765,
"loss_ee": 0.7000448107719421,
"loss_delivery": 0.29306168398923343,
"loss_biodist": 0.1472593926721149,
"loss_toxic": 0.049181385069257684
},
{
"loss": 0.807556238439348,
"loss_size": 0.27840375320778954,
"loss_pdi": 0.49708244535658097,
"loss_ee": 0.6255910860167609,
"loss_delivery": 0.28526460627714795,
"loss_biodist": 0.15456054194105995,
"loss_toxic": 0.06177276559174061
},
{
"loss": 0.7855066590838962,
"loss_size": 0.32354989979002213,
"loss_pdi": 0.4527622726228502,
"loss_ee": 0.6365198890368143,
"loss_delivery": 0.3020133003592491,
"loss_biodist": 0.12161805563502842,
"loss_toxic": 0.0547130216533939
},
{
"loss": 0.7482418417930603,
"loss_size": 0.28493734697500867,
"loss_pdi": 0.4469389385647244,
"loss_ee": 0.5961093968815274,
"loss_delivery": 0.26800185980068314,
"loss_biodist": 0.13538010004493925,
"loss_toxic": 0.06903231169821487
},
{
"loss": 0.7809840904341804,
"loss_size": 0.26718439989619786,
"loss_pdi": 0.42774680587980485,
"loss_ee": 0.6656727393468221,
"loss_delivery": 0.26476018379131955,
"loss_biodist": 0.15902242064476013,
"loss_toxic": 0.049143433519121676
},
{
"loss": 0.7012912034988403,
"loss_size": 0.262566520108117,
"loss_pdi": 0.39209893014695907,
"loss_ee": 0.5818678306208717,
"loss_delivery": 0.2516997829079628,
"loss_biodist": 0.12765472589267624,
"loss_toxic": 0.0697998855676916
},
{
"loss": 0.7463400032785203,
"loss_size": 0.24739450795782936,
"loss_pdi": 0.40411441690391964,
"loss_ee": 0.628772560093138,
"loss_delivery": 0.2954036576880349,
"loss_biodist": 0.1140976564751731,
"loss_toxic": 0.044662599762280784
},
{
"loss": 0.6163490811983744,
"loss_size": 0.288310459918446,
"loss_pdi": 0.36427528659502667,
"loss_ee": 0.6307892468240526,
"loss_delivery": 0.1889596382776896,
"loss_biodist": 0.09756135195493698,
"loss_toxic": 0.04955349138213529
},
{
"loss": 0.6405705908934275,
"loss_size": 0.2237887688808971,
"loss_pdi": 0.4110714726977878,
"loss_ee": 0.5337739255693223,
"loss_delivery": 0.2263336181640625,
"loss_biodist": 0.1061694473028183,
"loss_toxic": 0.04470060579478741
},
{
"loss": 0.7697069413132138,
"loss_size": 0.2463973437746366,
"loss_pdi": 0.38028954797320896,
"loss_ee": 0.6979360514216952,
"loss_delivery": 0.25414257248242694,
"loss_biodist": 0.16491614199346966,
"loss_toxic": 0.05081557719192157
},
{
"loss": 0.6620631052388085,
"loss_size": 0.2369771045115259,
"loss_pdi": 0.3893314798672994,
"loss_ee": 0.5603142148918576,
"loss_delivery": 0.23667338035172886,
"loss_biodist": 0.11451326393418843,
"loss_toxic": 0.04570075652251641
},
{
"loss": 0.6538277334637113,
"loss_size": 0.24913601846330696,
"loss_pdi": 0.3759702692429225,
"loss_ee": 0.5444082319736481,
"loss_delivery": 0.24537015333771706,
"loss_biodist": 0.10543231955832905,
"loss_toxic": 0.03996209127621518
},
{
"loss": 0.7225772241751353,
"loss_size": 0.4708017375734117,
"loss_pdi": 0.48318233092625934,
"loss_ee": 0.6235532595051659,
"loss_delivery": 0.24363002760542762,
"loss_biodist": 0.09773963110314475,
"loss_toxic": 0.04213416632006152
},
{
"loss": 0.6356318659252591,
"loss_size": 0.23396840194861093,
"loss_pdi": 0.39813413884904647,
"loss_ee": 0.5526859925852882,
"loss_delivery": 0.21145780819157758,
"loss_biodist": 0.11353611159655783,
"loss_toxic": 0.03990102968075209
},
{
"loss": 0.5867449641227722,
"loss_size": 0.26915082335472107,
"loss_pdi": 0.36582159333758885,
"loss_ee": 0.5152110689216189,
"loss_delivery": 0.18672772331370247,
"loss_biodist": 0.10546955714623134,
"loss_toxic": 0.06645603933268124
},
{
"loss": 0.5991987817817264,
"loss_size": 0.20178822841909197,
"loss_pdi": 0.36935993201202816,
"loss_ee": 0.5225964817735884,
"loss_delivery": 0.1933719146375855,
"loss_biodist": 0.11598552763462067,
"loss_toxic": 0.041511484421789646
}
],
"val": [
{
"loss": 4.203707377115886,
"loss_size": 12.5570068359375,
"loss_pdi": 1.328032414118449,
"loss_ee": 1.0009327133496602,
"loss_delivery": 1.1274526417255402,
"loss_biodist": 1.088600993156433,
"loss_toxic": 0.665272573630015,
"acc_pdi": 0.43023255813953487,
"acc_ee": 0.5930232558139535,
"acc_toxic": 0.6911764705882353
},
{
"loss": 2.9598995049794516,
"loss_size": 3.4258929093678794,
"loss_pdi": 1.0341591040293376,
"loss_ee": 0.9480661153793335,
"loss_delivery": 1.075680176417033,
"loss_biodist": 0.927180806795756,
"loss_toxic": 0.3956337769826253,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 2.4236873785654702,
"loss_size": 0.6928765177726746,
"loss_pdi": 0.8303105235099792,
"loss_ee": 0.9184248050053915,
"loss_delivery": 0.9723648031552633,
"loss_biodist": 0.8462505141894022,
"loss_toxic": 0.22327576577663422,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 2.2728907267252603,
"loss_size": 0.1453892414768537,
"loss_pdi": 0.7279466589291891,
"loss_ee": 0.8966926336288452,
"loss_delivery": 1.0309077699979146,
"loss_biodist": 0.7337591648101807,
"loss_toxic": 0.12586231033007303,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 1.8417518138885498,
"loss_size": 0.13176375130812326,
"loss_pdi": 0.6608819564183553,
"loss_ee": 0.8436107834180196,
"loss_delivery": 0.7991519669691721,
"loss_biodist": 0.5742160479227701,
"loss_toxic": 0.07719171792268753,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 1.6235692699750264,
"loss_size": 0.157888429860274,
"loss_pdi": 0.6255697806676229,
"loss_ee": 0.8376177350680033,
"loss_delivery": 0.7354667956630389,
"loss_biodist": 0.42997347315152484,
"loss_toxic": 0.06767919659614563,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 1.5600887934366863,
"loss_size": 0.17946209013462067,
"loss_pdi": 0.5976482232411703,
"loss_ee": 0.817159632841746,
"loss_delivery": 0.7114718655745188,
"loss_biodist": 0.40367170174916583,
"loss_toxic": 0.05113306765755018,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.5930232558139535,
"acc_toxic": 1.0
},
{
"loss": 1.4551989237467449,
"loss_size": 0.19508538643519083,
"loss_pdi": 0.5804279247919718,
"loss_ee": 0.8005453745524088,
"loss_delivery": 0.6614194512367249,
"loss_biodist": 0.3568926751613617,
"loss_toxic": 0.06172345206141472,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.6046511627906976,
"acc_toxic": 1.0
},
{
"loss": 1.4223628242810566,
"loss_size": 0.16839895397424698,
"loss_pdi": 0.5599722663561503,
"loss_ee": 0.7793195247650146,
"loss_delivery": 0.6651809612909952,
"loss_biodist": 0.33601675430933636,
"loss_toxic": 0.05075258140762647,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.6046511627906976,
"acc_toxic": 1.0
},
{
"loss": 1.4155388871828716,
"loss_size": 0.1747613549232483,
"loss_pdi": 0.5486661195755005,
"loss_ee": 0.7654038866360983,
"loss_delivery": 0.6517145584026972,
"loss_biodist": 0.3496930003166199,
"loss_toxic": 0.04868262136975924,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.6511627906976745,
"acc_toxic": 1.0
},
{
"loss": 1.418994426727295,
"loss_size": 0.20779606699943542,
"loss_pdi": 0.5416592955589294,
"loss_ee": 0.7802741527557373,
"loss_delivery": 0.6537248939275742,
"loss_biodist": 0.3444746732711792,
"loss_toxic": 0.06870528931419055,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.6511627906976745,
"acc_toxic": 1.0
},
{
"loss": 1.3367839654286702,
"loss_size": 0.1983067790667216,
"loss_pdi": 0.5345806876818339,
"loss_ee": 0.7629140814145406,
"loss_delivery": 0.5853411902983984,
"loss_biodist": 0.3388380706310272,
"loss_toxic": 0.07051138704021771,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.6511627906976745,
"acc_toxic": 1.0
},
{
"loss": 1.3901589512825012,
"loss_size": 0.1996572638551394,
"loss_pdi": 0.5183976491292318,
"loss_ee": 0.7431721488634745,
"loss_delivery": 0.6585398813088735,
"loss_biodist": 0.3291459232568741,
"loss_toxic": 0.08072975898782413,
"acc_pdi": 0.7790697674418605,
"acc_ee": 0.6976744186046512,
"acc_toxic": 1.0
},
{
"loss": 1.331486980120341,
"loss_size": 0.17860066890716553,
"loss_pdi": 0.512069841225942,
"loss_ee": 0.7535405953725179,
"loss_delivery": 0.6070386866728464,
"loss_biodist": 0.32369718452294666,
"loss_toxic": 0.06415784358978271,
"acc_pdi": 0.7674418604651163,
"acc_ee": 0.6511627906976745,
"acc_toxic": 1.0
},
{
"loss": 1.3827840089797974,
"loss_size": 0.18805266916751862,
"loss_pdi": 0.5040537615617117,
"loss_ee": 0.7437789042790731,
"loss_delivery": 0.6368728925784429,
"loss_biodist": 0.34890177845954895,
"loss_toxic": 0.07708448792497317,
"acc_pdi": 0.7790697674418605,
"acc_ee": 0.6744186046511628,
"acc_toxic": 1.0
},
{
"loss": 1.3310901920000713,
"loss_size": 0.18602455655733743,
"loss_pdi": 0.5110625525315603,
"loss_ee": 0.7455776532491049,
"loss_delivery": 0.6024594257275263,
"loss_biodist": 0.32696664333343506,
"loss_toxic": 0.12139131873846054,
"acc_pdi": 0.7674418604651163,
"acc_ee": 0.6511627906976745,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3631527423858643,
"loss_size": 0.1766586701075236,
"loss_pdi": 0.5037118991216024,
"loss_ee": 0.7329729199409485,
"loss_delivery": 0.6445856988430023,
"loss_biodist": 0.3245445191860199,
"loss_toxic": 0.10702474663654964,
"acc_pdi": 0.7906976744186046,
"acc_ee": 0.627906976744186,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.4047183990478516,
"loss_size": 0.1806520422299703,
"loss_pdi": 0.5002086162567139,
"loss_ee": 0.7287456591924032,
"loss_delivery": 0.6690659672021866,
"loss_biodist": 0.3438684443632762,
"loss_toxic": 0.10064958781003952,
"acc_pdi": 0.7906976744186046,
"acc_ee": 0.6395348837209303,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.333821694056193,
"loss_size": 0.1959198514620463,
"loss_pdi": 0.49203147490819293,
"loss_ee": 0.7277545134226481,
"loss_delivery": 0.5924984564383825,
"loss_biodist": 0.34934840599695843,
"loss_toxic": 0.12893996636072794,
"acc_pdi": 0.8023255813953488,
"acc_ee": 0.6511627906976745,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3231196999549866,
"loss_size": 0.16584139813979468,
"loss_pdi": 0.48038265109062195,
"loss_ee": 0.7447735865910848,
"loss_delivery": 0.595636452237765,
"loss_biodist": 0.3388388454914093,
"loss_toxic": 0.09026659031709035,
"acc_pdi": 0.813953488372093,
"acc_ee": 0.6395348837209303,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.321769932905833,
"loss_size": 0.14760359128316244,
"loss_pdi": 0.48214168349901837,
"loss_ee": 0.7435882687568665,
"loss_delivery": 0.608780970176061,
"loss_biodist": 0.3262732923030853,
"loss_toxic": 0.08472701907157898,
"acc_pdi": 0.7558139534883721,
"acc_ee": 0.6511627906976745,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.349458376566569,
"loss_size": 0.14423441886901855,
"loss_pdi": 0.49267129103342694,
"loss_ee": 0.7619675199190775,
"loss_delivery": 0.6184816459814707,
"loss_biodist": 0.334799200296402,
"loss_toxic": 0.10724820693333943,
"acc_pdi": 0.8023255813953488,
"acc_ee": 0.6511627906976745,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3972117900848389,
"loss_size": 0.14450456947088242,
"loss_pdi": 0.48599036534627277,
"loss_ee": 0.7444385290145874,
"loss_delivery": 0.6561772574981054,
"loss_biodist": 0.35264819860458374,
"loss_toxic": 0.09614282846450806,
"acc_pdi": 0.813953488372093,
"acc_ee": 0.6627906976744186,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.4228341182072957,
"loss_size": 0.14553842941919962,
"loss_pdi": 0.48066481947898865,
"loss_ee": 0.7501527269681295,
"loss_delivery": 0.6902634600798289,
"loss_biodist": 0.34465264280637103,
"loss_toxic": 0.08237827941775322,
"acc_pdi": 0.7906976744186046,
"acc_ee": 0.6395348837209303,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3808340628941853,
"loss_size": 0.1292742838462194,
"loss_pdi": 0.4865882893403371,
"loss_ee": 0.7392855286598206,
"loss_delivery": 0.6645563095808029,
"loss_biodist": 0.33053581913312274,
"loss_toxic": 0.10104685525099437,
"acc_pdi": 0.7674418604651163,
"acc_ee": 0.6511627906976745,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3559386332829793,
"loss_size": 0.16933744152386984,
"loss_pdi": 0.48616169889767963,
"loss_ee": 0.7289416988690695,
"loss_delivery": 0.6218888709942499,
"loss_biodist": 0.3469918568929036,
"loss_toxic": 0.11186282833417256,
"acc_pdi": 0.7441860465116279,
"acc_ee": 0.7093023255813954,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.4372685352961223,
"loss_size": 0.16308905184268951,
"loss_pdi": 0.48163432876269024,
"loss_ee": 0.742155134677887,
"loss_delivery": 0.6780142262578011,
"loss_biodist": 0.37172330419222516,
"loss_toxic": 0.08170524860421817,
"acc_pdi": 0.8023255813953488,
"acc_ee": 0.6744186046511628,
"acc_toxic": 0.9411764705882353
},
{
"loss": 1.4726805686950684,
"loss_size": 0.15727956344683966,
"loss_pdi": 0.48047395547231037,
"loss_ee": 0.7514520486195883,
"loss_delivery": 0.7308566917975744,
"loss_biodist": 0.352274755636851,
"loss_toxic": 0.08486517394582431,
"acc_pdi": 0.8255813953488372,
"acc_ee": 0.6976744186046512,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.455085535844167,
"loss_size": 0.14341105769077936,
"loss_pdi": 0.49014556407928467,
"loss_ee": 0.7744458913803101,
"loss_delivery": 0.721830815076828,
"loss_biodist": 0.335346798102061,
"loss_toxic": 0.0837879627943039,
"acc_pdi": 0.7674418604651163,
"acc_ee": 0.686046511627907,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3909406661987305,
"loss_size": 0.14493556569019952,
"loss_pdi": 0.4812280337015788,
"loss_ee": 0.7772515416145325,
"loss_delivery": 0.668215756615003,
"loss_biodist": 0.32652929425239563,
"loss_toxic": 0.08316347872217496,
"acc_pdi": 0.8023255813953488,
"acc_ee": 0.6744186046511628,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3612130085627239,
"loss_size": 0.14900055527687073,
"loss_pdi": 0.4703127642472585,
"loss_ee": 0.7645981311798096,
"loss_delivery": 0.6497406015793482,
"loss_biodist": 0.3219427764415741,
"loss_toxic": 0.08312482262651126,
"acc_pdi": 0.7906976744186046,
"acc_ee": 0.686046511627907,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3805859486262004,
"loss_size": 0.14480797201395035,
"loss_pdi": 0.4679768880208333,
"loss_ee": 0.7823085784912109,
"loss_delivery": 0.6536184350649515,
"loss_biodist": 0.3332401712735494,
"loss_toxic": 0.08321779345472653,
"acc_pdi": 0.813953488372093,
"acc_ee": 0.686046511627907,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3923940658569336,
"loss_size": 0.13573802759250006,
"loss_pdi": 0.4754982590675354,
"loss_ee": 0.7821588118871053,
"loss_delivery": 0.6637577960888544,
"loss_biodist": 0.33351930975914,
"loss_toxic": 0.08492095892628033,
"acc_pdi": 0.813953488372093,
"acc_ee": 0.6976744186046512,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.3863845070203145,
"loss_size": 0.1173308293024699,
"loss_pdi": 0.48561875025431317,
"loss_ee": 0.7768913904825846,
"loss_delivery": 0.6560828685760498,
"loss_biodist": 0.335321565469106,
"loss_toxic": 0.089879609644413,
"acc_pdi": 0.7906976744186046,
"acc_ee": 0.686046511627907,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.4132193525632222,
"loss_size": 0.1171627144018809,
"loss_pdi": 0.4863474667072296,
"loss_ee": 0.7720492482185364,
"loss_delivery": 0.6821378419796625,
"loss_biodist": 0.33687134583791095,
"loss_toxic": 0.09949792673190434,
"acc_pdi": 0.7790697674418605,
"acc_ee": 0.6976744186046512,
"acc_toxic": 0.9117647058823529
},
{
"loss": 1.4220859209696453,
"loss_size": 0.12649975468715033,
"loss_pdi": 0.4932010769844055,
"loss_ee": 0.7706326842308044,
"loss_delivery": 0.6895352651675543,
"loss_biodist": 0.33593428134918213,
"loss_toxic": 0.0963239644964536,
"acc_pdi": 0.7674418604651163,
"acc_ee": 0.6976744186046512,
"acc_toxic": 0.9117647058823529
}
]
}

BIN
models/finetune_cv/fold_4/loss_curves.png
View File

Binary file not shown.
Side by Side

Before

Width:  |  Height:  |  Size: 278 KiB

3
models/finetune_cv/fold_4/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:9fb343b9d4ce0d7cb46c7a9b75c5a5d2a04adde74adeb981a766245fb94155a3
size 28583404

294
models/finetune_cv/test_results.json
View File

@ -1,294 +0,0 @@
{
"fold_results": [
{
"fold_idx": 0,
"n_samples": 87,
"size": {
"n": 87,
"rmse": 0.5578980261231201,
"mae": 0.293820194814397,
"r2": -0.16350852977979646
},
"delivery": {
"n": 64,
"rmse": 1.4180242556680394,
"mae": 0.489678907149937,
"r2": 0.006066588761596381
},
"pdi": {
"n": 87,
"accuracy": 0.7011494252873564,
"precision": 0.382983682983683,
"recall": 0.3981244671781756,
"f1": 0.38831483607603007
},
"ee": {
"n": 87,
"accuracy": 0.6206896551724138,
"precision": 0.4700393567388641,
"recall": 0.5084656084656085,
"f1": 0.4656627032698024
},
"toxic": {
"n": 65,
"accuracy": 0.9846153846153847,
"precision": 0.9918032786885246,
"recall": 0.9,
"f1": 0.9403122130394859
},
"biodist": {
"n": 65,
"kl_divergence": 0.20084619060054956,
"js_divergence": 0.048292698388857934
}
},
{
"fold_idx": 1,
"n_samples": 87,
"size": {
"n": 87,
"rmse": 0.40406802223294774,
"mae": 0.2981993521767101,
"r2": 0.09717283856858072
},
"delivery": {
"n": 58,
"rmse": 0.545857341773909,
"mae": 0.3866841504832023,
"r2": 0.39045172405838346
},
"pdi": {
"n": 87,
"accuracy": 0.8045977011494253,
"precision": 0.49282452707110247,
"recall": 0.45567765567765567,
"f1": 0.4661145617667357
},
"ee": {
"n": 87,
"accuracy": 0.7241379310344828,
"precision": 0.7064586357039188,
"recall": 0.6503496503496503,
"f1": 0.6654761904761903
},
"toxic": {
"n": 59,
"accuracy": 0.9830508474576272,
"precision": 0.9912280701754386,
"recall": 0.8333333333333333,
"f1": 0.8955752212389381
},
"biodist": {
"n": 58,
"kl_divergence": 0.185822128176519,
"js_divergence": 0.049566546350752166
}
},
{
"fold_idx": 2,
"n_samples": 87,
"size": {
"n": 86,
"rmse": 0.5861093745094258,
"mae": 0.35274335949919944,
"r2": -0.3079648452189143
},
"delivery": {
"n": 61,
"rmse": 0.5034529339588798,
"mae": 0.3725305872618175,
"r2": 0.596618413667312
},
"pdi": {
"n": 87,
"accuracy": 0.7701149425287356,
"precision": 0.7266666666666666,
"recall": 0.6349206349206349,
"f1": 0.6497584541062802
},
"ee": {
"n": 87,
"accuracy": 0.5172413793103449,
"precision": 0.43155828639699606,
"recall": 0.40000766812361016,
"f1": 0.3980599647266314
},
"toxic": {
"n": 61,
"accuracy": 1.0,
"precision": 1.0,
"recall": 1.0,
"f1": 1.0
},
"biodist": {
"n": 61,
"kl_divergence": 0.2646404257700098,
"js_divergence": 0.07024299955112
}
},
{
"fold_idx": 3,
"n_samples": 86,
"size": {
"n": 86,
"rmse": 0.32742961478246685,
"mae": 0.25193805472795355,
"r2": -0.09589933555096875
},
"delivery": {
"n": 68,
"rmse": 0.7277366648519259,
"mae": 0.42998586144462664,
"r2": 0.4053674615039361
},
"pdi": {
"n": 86,
"accuracy": 0.7906976744186046,
"precision": 0.7513157894736842,
"recall": 0.6356534090909091,
"f1": 0.6544642857142857
},
"ee": {
"n": 86,
"accuracy": 0.7441860465116279,
"precision": 0.6962905144216474,
"recall": 0.6327243018419488,
"f1": 0.6557768628760061
},
"toxic": {
"n": 68,
"accuracy": 1.0,
"precision": 1.0,
"recall": 1.0,
"f1": 1.0
},
"biodist": {
"n": 68,
"kl_divergence": 0.3411994760293469,
"js_divergence": 0.07812197338009717
}
},
{
"fold_idx": 4,
"n_samples": 87,
"size": {
"n": 86,
"rmse": 0.28795189907825647,
"mae": 0.21156823080639506,
"r2": 0.2077479731717109
},
"delivery": {
"n": 59,
"rmse": 0.8048179107025805,
"mae": 0.5188011898327682,
"r2": 0.24048521206149798
},
"pdi": {
"n": 87,
"accuracy": 0.6896551724137931,
"precision": 0.4101075268817204,
"recall": 0.425,
"f1": 0.4174194267871083
},
"ee": {
"n": 87,
"accuracy": 0.7011494252873564,
"precision": 0.6600529100529101,
"recall": 0.581219806763285,
"f1": 0.5953238953238954
},
"toxic": {
"n": 60,
"accuracy": 0.95,
"precision": 0.8240740740740741,
"recall": 0.8818181818181818,
"f1": 0.8498748957464553
},
"biodist": {
"n": 59,
"kl_divergence": 0.207699088365002,
"js_divergence": 0.05288953180347253
}
}
],
"summary_stats": {
"size": {
"rmse_mean": 0.43269138734524343,
"rmse_std": 0.12005218734930377,
"r2_mean": -0.05249037976187758,
"r2_std": 0.18417364026118202
},
"delivery": {
"rmse_mean": 0.7999778213910669,
"rmse_std": 0.3285507063187239,
"r2_mean": 0.32779788001054516,
"r2_std": 0.19664259417310184
},
"pdi": {
"accuracy_mean": 0.751242983159583,
"accuracy_std": 0.04703609766404652,
"f1_mean": 0.515214312890088,
"f1_std": 0.11451705845950987
},
"ee": {
"accuracy_mean": 0.6614808874632452,
"accuracy_std": 0.08343692429542732,
"f1_mean": 0.5560599233345052,
"f1_std": 0.10638861908930271
},
"toxic": {
"accuracy_mean": 0.9835332464146024,
"accuracy_std": 0.018265761928954075,
"f1_mean": 0.9371524660049758,
"f1_std": 0.05874632007606866
},
"biodist": {
"kl_mean": 0.24004146178828548,
"kl_std": 0.05720155140134621,
"js_mean": 0.05982274989485996,
"js_std": 0.012080103435264247
}
},
"overall": {
"size": {
"n_samples": 432,
"mse": 0.20179930058631468,
"rmse": 0.44922077043065883,
"mae": 0.2817203010673876,
"r2": -0.09923811531698323
},
"delivery": {
"n_samples": 310,
"mse": 0.760202623547859,
"rmse": 0.8718959935381393,
"mae": 0.4398058238289049,
"r2": 0.23486100707044422
},
"pdi": {
"n_samples": 434,
"accuracy": 0.7511520737327189,
"precision": 0.3287852263755878,
"recall": 0.3184060228452752,
"f1": 0.3212571677885814
},
"ee": {
"n_samples": 434,
"accuracy": 0.6612903225806451,
"precision": 0.5836247086247086,
"recall": 0.5469842657342657,
"f1": 0.5597637622559741
},
"toxic": {
"n_samples": 313,
"accuracy": 0.9840255591054313,
"precision": 0.918076923076923,
"recall": 0.8895126612517916,
"f1": 0.9032337847028998
},
"biodist": {
"n_samples": 311,
"kl_divergence": 0.24254521665201,
"js_divergence": 0.06022985409160514
}
}
}

3
models/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:dd7545e5a3694a930885f008103154ccafbe51cd7741f29e60721e2d72f57a3d
size 27959366

11
models/nested_cv/20260302_110648/outer_fold_0/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.13138363142855383,
"lr": 0.0003183893957684731,
"weight_decay": 0.09324304909602012,
"backbone_lr_ratio": 0.35598913444921026,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

1
models/nested_cv/20260302_110648/outer_fold_0/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 14}

131
models/nested_cv/20260302_110648/outer_fold_0/history.json Normal file
View File

@ -0,0 +1,131 @@
{
"train": [
{
"loss": 17.683713739568535,
"loss_size": 12.651358431035822,
"loss_pdi": 1.2311409007419238,
"loss_ee": 1.0776630206541582,
"loss_delivery": 0.990076406435533,
"loss_biodist": 1.0874592011625117,
"loss_toxic": 0.646015855399045
},
{
"loss": 5.022838289087469,
"loss_size": 0.8055560128255324,
"loss_pdi": 0.960849176753651,
"loss_ee": 1.0541732744737105,
"loss_delivery": 0.9265002337369052,
"loss_biodist": 0.7412944544445385,
"loss_toxic": 0.5344653617252003
},
{
"loss": 3.934074488553134,
"loss_size": 0.40558130835944955,
"loss_pdi": 0.802710928700187,
"loss_ee": 1.0141955668276006,
"loss_delivery": 0.9183592362837358,
"loss_biodist": 0.4602292396805503,
"loss_toxic": 0.33299820531498303
},
{
"loss": 3.288050413131714,
"loss_size": 0.27515405958349054,
"loss_pdi": 0.7602007551626726,
"loss_ee": 0.9728038527748801,
"loss_delivery": 0.7759204127571799,
"loss_biodist": 0.31733120571483264,
"loss_toxic": 0.18664006109942088
},
{
"loss": 3.080135367133401,
"loss_size": 0.22799434783783826,
"loss_pdi": 0.7197960615158081,
"loss_ee": 0.9530497789382935,
"loss_delivery": 0.8002918457443063,
"loss_biodist": 0.22455358437516473,
"loss_toxic": 0.1544497168876908
},
{
"loss": 2.7855641191655938,
"loss_size": 0.22336075522682883,
"loss_pdi": 0.6980533328923312,
"loss_ee": 0.8968175595456903,
"loss_delivery": 0.6557027047330682,
"loss_biodist": 0.1885258440266956,
"loss_toxic": 0.12310385602441701
},
{
"loss": 2.59962120923129,
"loss_size": 0.22615284811366687,
"loss_pdi": 0.6547347198833119,
"loss_ee": 0.8711694099686362,
"loss_delivery": 0.5687765330076218,
"loss_biodist": 0.16510199755430222,
"loss_toxic": 0.11368572551079771
},
{
"loss": 2.590689193118702,
"loss_size": 0.2277267866513946,
"loss_pdi": 0.664570765061812,
"loss_ee": 0.8439542813734575,
"loss_delivery": 0.607647177847949,
"loss_biodist": 0.1554033627564257,
"loss_toxic": 0.09138677997345274
},
{
"loss": 2.4292859489267524,
"loss_size": 0.19391338933597912,
"loss_pdi": 0.6154463995586742,
"loss_ee": 0.8015681613575328,
"loss_delivery": 0.6012924083254554,
"loss_biodist": 0.13535428927703338,
"loss_toxic": 0.08171129053119909
},
{
"loss": 2.4555776661092583,
"loss_size": 0.21898228539661926,
"loss_pdi": 0.6125041002577002,
"loss_ee": 0.7959883213043213,
"loss_delivery": 0.6148059842261401,
"loss_biodist": 0.14537827535109085,
"loss_toxic": 0.0679187753491781
},
{
"loss": 2.3277205770665947,
"loss_size": 0.18986415321176703,
"loss_pdi": 0.6249966973608191,
"loss_ee": 0.7996126250787214,
"loss_delivery": 0.4938020712950013,
"loss_biodist": 0.13543404571034692,
"loss_toxic": 0.08401098576459018
},
{
"loss": 2.244856910272078,
"loss_size": 0.18505191599780862,
"loss_pdi": 0.5941501639106057,
"loss_ee": 0.768797988241369,
"loss_delivery": 0.5105205489830538,
"loss_biodist": 0.13239529796622015,
"loss_toxic": 0.05394093243574554
},
{
"loss": 2.2451160821047695,
"loss_size": 0.21409614113244144,
"loss_pdi": 0.5725546452132139,
"loss_ee": 0.7525453188202598,
"loss_delivery": 0.5198689279231158,
"loss_biodist": 0.12487202137708664,
"loss_toxic": 0.061179049355401235
},
{
"loss": 2.2677728696302935,
"loss_size": 0.21982615982944315,
"loss_pdi": 0.5889222161336378,
"loss_ee": 0.7615910172462463,
"loss_delivery": 0.5028471987355839,
"loss_biodist": 0.1265682794831016,
"loss_toxic": 0.06801802131601355
}
],
"val": []
}

3
models/nested_cv/20260302_110648/outer_fold_0/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:30121e051b170ee1c9e454e193c762e721e32682b9a000bd9361c7dcd6f963f7
size 28583340

BIN
models/nested_cv/20260302_110648/outer_fold_0/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

1
models/nested_cv/20260302_110648/outer_fold_0/splits.json Normal file
View File

@ -0,0 +1 @@
{"outer_train_idx": [0, 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19, 21, 22, 23, 24, 25, 26, 27, 28, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 52, 53, 54, 55, 56, 57, 58, 61, 62, 63, 64, 65, 66, 67, 68, 71, 72, 73, 75, 76, 77, 80, 81, 85, 86, 88, 89, 90, 92, 94, 95, 96, 98, 99, 100, 101, 103, 104, 105, 106, 107, 108, 109, 111, 113, 114, 115, 116, 117, 118, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 133, 134, 135, 136, 138, 139, 141, 144, 145, 146, 147, 148, 149, 150, 151, 153, 154, 155, 156, 157, 158, 159, 160, 163, 164, 167, 168, 169, 170, 171, 172, 175, 176, 178, 179, 180, 182, 183, 184, 185, 188, 189, 190, 191, 192, 193, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 206, 208, 210, 211, 212, 213, 216, 217, 218, 219, 220, 222, 224, 225, 227, 228, 229, 230, 231, 232, 233, 234, 236, 237, 239, 241, 242, 244, 245, 247, 248, 249, 250, 252, 253, 255, 256, 257, 258, 259, 260, 261, 262, 265, 267, 268, 269, 270, 271, 272, 274, 275, 276, 277, 278, 279, 280, 281, 282, 283, 285, 286, 287, 288, 291, 292, 294, 296, 297, 298, 299, 300, 301, 303, 304, 306, 307, 308, 309, 310, 311, 312, 313, 316, 317, 318, 319, 320, 321, 322, 323, 324, 325, 326, 327, 328, 329, 330, 332, 333, 335, 336, 337, 338, 339, 340, 342, 343, 344, 345, 346, 347, 348, 349, 351, 352, 354, 355, 356, 357, 358, 359, 360, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 374, 375, 377, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 390, 391, 393, 395, 396, 397, 398, 399, 400, 401, 403, 404, 405, 406, 407, 408, 409, 411, 412, 413, 414, 415, 417, 418, 419], "outer_test_idx": [7, 16, 20, 29, 51, 59, 60, 69, 70, 74, 78, 79, 82, 83, 84, 87, 91, 93, 97, 102, 110, 112, 119, 120, 121, 132, 137, 140, 142, 143, 152, 161, 162, 165, 166, 173, 174, 177, 181, 186, 187, 194, 205, 207, 209, 214, 215, 221, 223, 226, 235, 238, 240, 243, 246, 251, 254, 263, 264, 266, 273, 284, 289, 290, 293, 295, 302, 305, 314, 315, 331, 334, 341, 350, 353, 361, 373, 376, 378, 392, 394, 402, 410, 416]}

42
models/nested_cv/20260302_110648/outer_fold_0/test_metrics.json Normal file
View File

@ -0,0 +1,42 @@
{
"size": {
"n_samples": 83,
"mse": 0.3019449796801696,
"rmse": 0.5494952044196287,
"mae": 0.2869321725454675,
"r2": -0.002565673822219283
},
"delivery": {
"n_samples": 58,
"mse": 0.4861564349157676,
"rmse": 0.6972491914056033,
"mae": 0.5075679545387112,
"r2": 0.3820658346383613
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6428571428571429,
"precision": 0.3838387806411062,
"recall": 0.5765027322404371,
"f1": 0.4081896551724138
},
"ee": {
"n_samples": 84,
"accuracy": 0.7261904761904762,
"precision": 0.6957516339869282,
"recall": 0.7652380952380953,
"f1": 0.7042577030812325
},
"toxic": {
"n_samples": 58,
"accuracy": 0.9310344827586207,
"precision": 0.6157407407407407,
"recall": 0.7232142857142857,
"f1": 0.6484848484848484
},
"biodist": {
"n_samples": 58,
"kl_divergence": 0.1773200742051057,
"js_divergence": 0.038189943291577606
}
}

11
models/nested_cv/20260302_110648/outer_fold_1/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.11160552976974417,
"lr": 0.0002934246482004709,
"weight_decay": 0.000380014417451246,
"backbone_lr_ratio": 0.40187800461703077,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

1
models/nested_cv/20260302_110648/outer_fold_1/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 11}

104
models/nested_cv/20260302_110648/outer_fold_1/history.json Normal file
View File

@ -0,0 +1,104 @@
{
"train": [
{
"loss": 12.697397752241654,
"loss_size": 7.74959254806692,
"loss_pdi": 1.3255384293469517,
"loss_ee": 1.072592399337075,
"loss_delivery": 0.8493569059805437,
"loss_biodist": 1.0891072750091553,
"loss_toxic": 0.6112104871056296
},
{
"loss": 4.646587631919167,
"loss_size": 0.44177047366445715,
"loss_pdi": 1.12606712362983,
"loss_ee": 1.0141103646971963,
"loss_delivery": 0.8007846569473093,
"loss_biodist": 0.7099857059392062,
"loss_toxic": 0.5538693151690743
},
{
"loss": 3.5969873558391225,
"loss_size": 0.32526642084121704,
"loss_pdi": 0.9513758420944214,
"loss_ee": 0.9207825552333485,
"loss_delivery": 0.7346462499011647,
"loss_biodist": 0.4319412518631328,
"loss_toxic": 0.23297495598142798
},
{
"loss": 3.110519365830855,
"loss_size": 0.27337742393667047,
"loss_pdi": 0.8270606073466215,
"loss_ee": 0.8627686175433072,
"loss_delivery": 0.684851122173396,
"loss_biodist": 0.2946568321097981,
"loss_toxic": 0.1678048074245453
},
{
"loss": 2.674631270495328,
"loss_size": 0.23272697627544403,
"loss_pdi": 0.7205180363221602,
"loss_ee": 0.8004498752680692,
"loss_delivery": 0.5861585221507333,
"loss_biodist": 0.23780989375981418,
"loss_toxic": 0.09696798195893114
},
{
"loss": 2.5125140601938423,
"loss_size": 0.2434661625461145,
"loss_pdi": 0.6888363036242399,
"loss_ee": 0.7625214620070024,
"loss_delivery": 0.5486936596306887,
"loss_biodist": 0.19384850290688602,
"loss_toxic": 0.07514794170856476
},
{
"loss": 2.39500110799616,
"loss_size": 0.2201431400396607,
"loss_pdi": 0.6409280489791523,
"loss_ee": 0.7487377903678201,
"loss_delivery": 0.5459823933514681,
"loss_biodist": 0.17606976696036078,
"loss_toxic": 0.0631399959410456
},
{
"loss": 2.251852349801497,
"loss_size": 0.18387161669406024,
"loss_pdi": 0.6120052906599912,
"loss_ee": 0.7214207378300753,
"loss_delivery": 0.5001139681447636,
"loss_biodist": 0.1708781678568233,
"loss_toxic": 0.0635625630278479
},
{
"loss": 2.2666824622587725,
"loss_size": 0.20021018453619696,
"loss_pdi": 0.6474456868388436,
"loss_ee": 0.7374396269971674,
"loss_delivery": 0.47504283250732854,
"loss_biodist": 0.1507004587487741,
"loss_toxic": 0.055843705565414646
},
{
"loss": 2.1942475709048184,
"loss_size": 0.17434797977859323,
"loss_pdi": 0.6297436058521271,
"loss_ee": 0.7001124566251581,
"loss_delivery": 0.46643866327675904,
"loss_biodist": 0.14881570027633148,
"loss_toxic": 0.07478914723138917
},
{
"loss": 2.177516893907027,
"loss_size": 0.19244792447848755,
"loss_pdi": 0.5950825756246393,
"loss_ee": 0.6885340782729062,
"loss_delivery": 0.4849355329166759,
"loss_biodist": 0.1637753810394894,
"loss_toxic": 0.05274138929830356
}
],
"val": []
}

3
models/nested_cv/20260302_110648/outer_fold_1/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:5533a3b2a22d3f4545edb3418ca1c0071ca37a7ca9dcc02a6cab29f384200195
size 28583340

BIN
models/nested_cv/20260302_110648/outer_fold_1/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

1
models/nested_cv/20260302_110648/outer_fold_1/splits.json Normal file
View File

@ -0,0 +1 @@
{"outer_train_idx": [0, 3, 5, 6, 7, 10, 11, 12, 13, 15, 16, 18, 19, 20, 21, 24, 26, 27, 29, 30, 31, 32, 33, 35, 36, 38, 39, 40, 42, 44, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 65, 66, 67, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 97, 98, 99, 100, 101, 102, 103, 105, 106, 107, 108, 109, 110, 112, 114, 115, 118, 119, 120, 121, 123, 124, 125, 126, 128, 129, 130, 131, 132, 136, 137, 140, 141, 142, 143, 144, 145, 146, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 161, 162, 164, 165, 166, 167, 168, 169, 171, 172, 173, 174, 175, 176, 177, 178, 179, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 194, 195, 196, 197, 198, 199, 201, 202, 204, 205, 206, 207, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 225, 226, 228, 229, 231, 232, 233, 234, 235, 236, 237, 238, 240, 242, 243, 244, 246, 247, 248, 250, 251, 252, 254, 255, 256, 258, 259, 260, 261, 262, 263, 264, 266, 268, 269, 270, 271, 273, 274, 275, 276, 277, 278, 279, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 295, 296, 297, 300, 301, 302, 303, 304, 305, 306, 307, 308, 310, 311, 313, 314, 315, 316, 317, 318, 319, 321, 322, 323, 324, 325, 327, 328, 329, 330, 331, 333, 334, 335, 337, 338, 339, 340, 341, 342, 343, 344, 345, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 361, 362, 364, 365, 366, 367, 368, 369, 373, 374, 375, 376, 378, 379, 380, 381, 382, 384, 387, 388, 389, 391, 392, 393, 394, 396, 397, 398, 399, 402, 403, 404, 405, 406, 408, 409, 410, 411, 412, 413, 414, 416, 417, 419], "outer_test_idx": [1, 2, 4, 8, 9, 14, 17, 22, 23, 25, 28, 34, 37, 41, 43, 45, 63, 64, 68, 85, 96, 104, 111, 113, 116, 117, 122, 127, 133, 134, 135, 138, 139, 147, 160, 163, 170, 180, 191, 192, 193, 200, 203, 208, 224, 227, 230, 239, 241, 245, 249, 253, 257, 265, 267, 272, 280, 294, 298, 299, 309, 312, 320, 326, 332, 336, 346, 347, 360, 363, 370, 371, 372, 377, 383, 385, 386, 390, 395, 400, 401, 407, 415, 418]}

42
models/nested_cv/20260302_110648/outer_fold_1/test_metrics.json Normal file
View File

@ -0,0 +1,42 @@
{
"size": {
"n_samples": 84,
"mse": 0.06851485629954368,
"rmse": 0.2617534265287537,
"mae": 0.19058226403735934,
"r2": -0.1350613967945693
},
"delivery": {
"n_samples": 61,
"mse": 0.8536548404567659,
"rmse": 0.9239344351504417,
"mae": 0.5235513564138139,
"r2": 0.3538448248397684
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6309523809523809,
"precision": 0.30528846153846156,
"recall": 0.28174603174603174,
"f1": 0.291304347826087
},
"ee": {
"n_samples": 84,
"accuracy": 0.5714285714285714,
"precision": 0.5202020202020202,
"recall": 0.5292564578278864,
"f1": 0.5119174942704355
},
"toxic": {
"n_samples": 61,
"accuracy": 0.9508196721311475,
"precision": 0.75,
"recall": 0.9741379310344828,
"f1": 0.8200589970501475
},
"biodist": {
"n_samples": 61,
"kl_divergence": 0.17284391250731643,
"js_divergence": 0.04385579372373865
}
}

11
models/nested_cv/20260302_110648/outer_fold_2/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.18117503720006686,
"lr": 8.135394049241399e-05,
"weight_decay": 0.015076469897649124,
"backbone_lr_ratio": 0.9586175198423679,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

1
models/nested_cv/20260302_110648/outer_fold_2/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 25}

230
models/nested_cv/20260302_110648/outer_fold_2/history.json Normal file
View File

@ -0,0 +1,230 @@
{
"train": [
{
"loss": 21.39721965789795,
"loss_size": 15.99975516579368,
"loss_pdi": 1.4032854600386186,
"loss_ee": 1.0602913011204114,
"loss_delivery": 1.050997108221054,
"loss_biodist": 1.2080710476095027,
"loss_toxic": 0.6748196265914224
},
{
"loss": 10.259548924186014,
"loss_size": 5.184145320545543,
"loss_pdi": 1.372773452238603,
"loss_ee": 1.0454044992273503,
"loss_delivery": 1.012099184773185,
"loss_biodist": 1.015745298428969,
"loss_toxic": 0.6293809847398237
},
{
"loss": 6.255305593663996,
"loss_size": 1.1491282365538857,
"loss_pdi": 1.3361019871451638,
"loss_ee": 1.069514740597118,
"loss_delivery": 1.143438840454275,
"loss_biodist": 0.919458573514765,
"loss_toxic": 0.6376630826429888
},
{
"loss": 4.9688051397150215,
"loss_size": 0.3698929670182141,
"loss_pdi": 1.1965981288389727,
"loss_ee": 1.073096221143549,
"loss_delivery": 0.9345543167807839,
"loss_biodist": 0.7975217158144171,
"loss_toxic": 0.597141832113266
},
{
"loss": 4.573386083949696,
"loss_size": 0.4143762006001039,
"loss_pdi": 1.1375520012595437,
"loss_ee": 1.0195629054849797,
"loss_delivery": 0.890605241060257,
"loss_biodist": 0.6563914743336764,
"loss_toxic": 0.4548980810425498
},
{
"loss": 4.101544965397228,
"loss_size": 0.43914192102172156,
"loss_pdi": 1.0022626465017146,
"loss_ee": 0.9604968320239674,
"loss_delivery": 0.8523516356945038,
"loss_biodist": 0.5347421656955372,
"loss_toxic": 0.3125497062097896
},
{
"loss": 3.661057537252253,
"loss_size": 0.3889053531668403,
"loss_pdi": 0.9442321495576338,
"loss_ee": 0.9463063153353605,
"loss_delivery": 0.7403370683843439,
"loss_biodist": 0.4202399958263744,
"loss_toxic": 0.22103659808635712
},
{
"loss": 3.386981422250921,
"loss_size": 0.3482015810229562,
"loss_pdi": 0.8426849787885492,
"loss_ee": 0.9068041172894564,
"loss_delivery": 0.7536717748100107,
"loss_biodist": 0.34633775732733985,
"loss_toxic": 0.18928123807365244
},
{
"loss": 3.212600209496238,
"loss_size": 0.3459387509660287,
"loss_pdi": 0.8124108856374567,
"loss_ee": 0.8988373983990062,
"loss_delivery": 0.7102516185153614,
"loss_biodist": 0.2967488007111983,
"loss_toxic": 0.14841275458986108
},
{
"loss": 3.0580417893149634,
"loss_size": 0.3329975523731925,
"loss_pdi": 0.7909485535188154,
"loss_ee": 0.8650063493035056,
"loss_delivery": 0.6246220415288751,
"loss_biodist": 0.2767850323156877,
"loss_toxic": 0.16768223250454123
},
{
"loss": 3.013258782300082,
"loss_size": 0.34031115065921436,
"loss_pdi": 0.7887083725495772,
"loss_ee": 0.8478339802135121,
"loss_delivery": 0.6795477948405526,
"loss_biodist": 0.23764747245745224,
"loss_toxic": 0.11920999871058897
},
{
"loss": 2.8098002780567515,
"loss_size": 0.2911471345207908,
"loss_pdi": 0.7486344196579673,
"loss_ee": 0.8292865373871543,
"loss_delivery": 0.6138625835830515,
"loss_biodist": 0.22263149375265295,
"loss_toxic": 0.10423808578740466
},
{
"loss": 2.668950471011075,
"loss_size": 0.2901349054141478,
"loss_pdi": 0.6930872662500902,
"loss_ee": 0.8307610099965875,
"loss_delivery": 0.5515611280094493,
"loss_biodist": 0.20567151362245734,
"loss_toxic": 0.09773457727648995
},
{
"loss": 2.66579270362854,
"loss_size": 0.29428902945735236,
"loss_pdi": 0.7022816647182811,
"loss_ee": 0.8060143860903654,
"loss_delivery": 0.576013707979159,
"loss_biodist": 0.19162616336887534,
"loss_toxic": 0.09556775743311102
},
{
"loss": 2.626258124004711,
"loss_size": 0.30222149328751996,
"loss_pdi": 0.7173665409738367,
"loss_ee": 0.7985508658669211,
"loss_delivery": 0.5140190422534943,
"loss_biodist": 0.1985876594077457,
"loss_toxic": 0.09551253948699344
},
{
"loss": 2.6027931733564897,
"loss_size": 0.30901888554746454,
"loss_pdi": 0.6719211773438887,
"loss_ee": 0.7768192508003928,
"loss_delivery": 0.5479655848308043,
"loss_biodist": 0.1939314597032287,
"loss_toxic": 0.10313683037053455
},
{
"loss": 2.5074240511113945,
"loss_size": 0.3031176735054363,
"loss_pdi": 0.6534268476746299,
"loss_ee": 0.7633791349150918,
"loss_delivery": 0.5091986588456414,
"loss_biodist": 0.18002587692304092,
"loss_toxic": 0.09827585027299145
},
{
"loss": 2.4758940393274482,
"loss_size": 0.2865243730219928,
"loss_pdi": 0.6496224132451144,
"loss_ee": 0.7556723356246948,
"loss_delivery": 0.5057628723708066,
"loss_biodist": 0.18768334253267807,
"loss_toxic": 0.09062876806340435
},
{
"loss": 2.450171535665339,
"loss_size": 0.2632152478803288,
"loss_pdi": 0.6468299627304077,
"loss_ee": 0.7730839035727761,
"loss_delivery": 0.5256320928985422,
"loss_biodist": 0.16883064400066028,
"loss_toxic": 0.07257966832681136
},
{
"loss": 2.4369121573188086,
"loss_size": 0.2788824357769706,
"loss_pdi": 0.613761305809021,
"loss_ee": 0.771127001805739,
"loss_delivery": 0.5181381458585913,
"loss_biodist": 0.18641300160776486,
"loss_toxic": 0.06859026205810634
},
{
"loss": 2.417920220981945,
"loss_size": 0.23204585097052835,
"loss_pdi": 0.6393328254873102,
"loss_ee": 0.7515245079994202,
"loss_delivery": 0.5089004351334139,
"loss_biodist": 0.1946206580508839,
"loss_toxic": 0.09149592894722115
},
{
"loss": 2.3215431841936978,
"loss_size": 0.23972267386588184,
"loss_pdi": 0.5877326103773984,
"loss_ee": 0.754569871859117,
"loss_delivery": 0.49636011028831656,
"loss_biodist": 0.171014394949783,
"loss_toxic": 0.07214344834739511
},
{
"loss": 2.391831939870661,
"loss_size": 0.24707127904350107,
"loss_pdi": 0.646995874968442,
"loss_ee": 0.7581986568190835,
"loss_delivery": 0.5030756457285448,
"loss_biodist": 0.1616102314808152,
"loss_toxic": 0.07488023218783466
},
{
"loss": 2.3657465522939507,
"loss_size": 0.24736730347980151,
"loss_pdi": 0.609911325302991,
"loss_ee": 0.7485404393889687,
"loss_delivery": 0.5186005532741547,
"loss_biodist": 0.17398183183236557,
"loss_toxic": 0.06734508208253166
},
{
"loss": 2.4681317156011406,
"loss_size": 0.2727768082510341,
"loss_pdi": 0.6348137990994887,
"loss_ee": 0.7562027736143633,
"loss_delivery": 0.5683451145887375,
"loss_biodist": 0.17328390343622727,
"loss_toxic": 0.0627093587748029
}
],
"val": []
}

3
models/nested_cv/20260302_110648/outer_fold_2/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:2daf709f5a5fe1f75469ff028bf0afc346d5be88150324d19d62992577ce3394
size 28583340

BIN
models/nested_cv/20260302_110648/outer_fold_2/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

1
models/nested_cv/20260302_110648/outer_fold_2/splits.json Normal file
View File

@ -0,0 +1 @@
{"outer_train_idx": [0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 13, 14, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 33, 34, 36, 37, 38, 39, 40, 41, 43, 44, 45, 47, 48, 49, 50, 51, 55, 56, 57, 58, 59, 60, 61, 63, 64, 65, 68, 69, 70, 72, 74, 76, 78, 79, 80, 82, 83, 84, 85, 86, 87, 88, 91, 93, 94, 95, 96, 97, 100, 101, 102, 103, 104, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 142, 143, 145, 147, 148, 149, 150, 151, 152, 153, 156, 157, 158, 159, 160, 161, 162, 163, 165, 166, 167, 168, 170, 171, 172, 173, 174, 175, 177, 179, 180, 181, 183, 184, 185, 186, 187, 188, 191, 192, 193, 194, 196, 197, 199, 200, 202, 203, 204, 205, 207, 208, 209, 210, 211, 212, 213, 214, 215, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 232, 233, 235, 236, 237, 238, 239, 240, 241, 242, 243, 245, 246, 249, 250, 251, 252, 253, 254, 255, 256, 257, 259, 260, 261, 263, 264, 265, 266, 267, 268, 269, 271, 272, 273, 274, 275, 276, 280, 281, 282, 283, 284, 285, 287, 289, 290, 293, 294, 295, 296, 297, 298, 299, 300, 302, 303, 305, 307, 308, 309, 310, 311, 312, 313, 314, 315, 317, 318, 320, 321, 322, 323, 324, 326, 327, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 358, 360, 361, 363, 364, 365, 366, 368, 369, 370, 371, 372, 373, 376, 377, 378, 379, 380, 381, 382, 383, 385, 386, 387, 388, 389, 390, 392, 394, 395, 398, 399, 400, 401, 402, 404, 405, 407, 408, 409, 410, 412, 413, 414, 415, 416, 417, 418], "outer_test_idx": [10, 12, 15, 31, 35, 42, 46, 52, 53, 54, 62, 66, 67, 71, 73, 75, 77, 81, 89, 90, 92, 98, 99, 105, 123, 124, 141, 144, 146, 154, 155, 164, 169, 176, 178, 182, 189, 190, 195, 198, 201, 206, 216, 217, 218, 219, 231, 234, 244, 247, 248, 258, 262, 270, 277, 278, 279, 286, 288, 291, 292, 301, 304, 306, 316, 319, 325, 328, 343, 357, 359, 362, 367, 374, 375, 384, 391, 393, 396, 397, 403, 406, 411, 419]}

42
models/nested_cv/20260302_110648/outer_fold_2/test_metrics.json Normal file
View File

@ -0,0 +1,42 @@
{
"size": {
"n_samples": 84,
"mse": 0.09662744334561678,
"rmse": 0.3108495509818484,
"mae": 0.23867071242559523,
"r2": -0.03533227905101599
},
"delivery": {
"n_samples": 60,
"mse": 0.6406059342358218,
"rmse": 0.8003786193020287,
"mae": 0.5084985921236996,
"r2": 0.147242469212558
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6071428571428571,
"precision": 0.3536231884057971,
"recall": 0.5382104454685099,
"f1": 0.37173202614379086
},
"ee": {
"n_samples": 84,
"accuracy": 0.6547619047619048,
"precision": 0.6023391812865497,
"recall": 0.6626984126984127,
"f1": 0.615613004906073
},
"toxic": {
"n_samples": 61,
"accuracy": 0.9508196721311475,
"precision": 0.75,
"recall": 0.9741379310344828,
"f1": 0.8200589970501475
},
"biodist": {
"n_samples": 60,
"kl_divergence": 0.14159162897750524,
"js_divergence": 0.03735438196115702
}
}

11
models/nested_cv/20260302_110648/outer_fold_3/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.1463802845991778,
"lr": 0.00017979738268552602,
"weight_decay": 0.026590603512062855,
"backbone_lr_ratio": 0.19962036354162335,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

1
models/nested_cv/20260302_110648/outer_fold_3/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 21}

194
models/nested_cv/20260302_110648/outer_fold_3/history.json Normal file
View File

@ -0,0 +1,194 @@
{
"train": [
{
"loss": 23.25593306801536,
"loss_size": 17.932933287187055,
"loss_pdi": 1.4047781445763328,
"loss_ee": 1.0787252512845127,
"loss_delivery": 0.997360042550347,
"loss_biodist": 1.1312900402329185,
"loss_toxic": 0.7108464999632402
},
{
"loss": 13.717705033042215,
"loss_size": 9.086629087274725,
"loss_pdi": 1.249630863016302,
"loss_ee": 1.020777626471086,
"loss_delivery": 0.8971629738807678,
"loss_biodist": 0.8823697458614003,
"loss_toxic": 0.5811346606774763
},
{
"loss": 6.37502349506725,
"loss_size": 2.146685239943591,
"loss_pdi": 1.189297686923634,
"loss_ee": 1.0045386281880466,
"loss_delivery": 0.8445947766304016,
"loss_biodist": 0.6946320208636197,
"loss_toxic": 0.49527510187842627
},
{
"loss": 4.364245089617643,
"loss_size": 0.36455209282311524,
"loss_pdi": 1.1105956868691877,
"loss_ee": 1.0037371570413762,
"loss_delivery": 0.8476319827816703,
"loss_biodist": 0.6052308136766608,
"loss_toxic": 0.43249731307679956
},
{
"loss": 3.899352182041515,
"loss_size": 0.30160820619626477,
"loss_pdi": 0.9745158986611799,
"loss_ee": 0.9776112816550515,
"loss_delivery": 0.782389222220941,
"loss_biodist": 0.4751999242739244,
"loss_toxic": 0.3880275826562535
},
{
"loss": 3.563619765368375,
"loss_size": 0.3334889669309963,
"loss_pdi": 0.9135042916644703,
"loss_ee": 0.9318695230917498,
"loss_delivery": 0.7443146895278584,
"loss_biodist": 0.40273872830651025,
"loss_toxic": 0.23770355026830325
},
{
"loss": 3.2734298489310523,
"loss_size": 0.25410358201373706,
"loss_pdi": 0.8603565421971408,
"loss_ee": 0.9201914505525068,
"loss_delivery": 0.7122206769206307,
"loss_biodist": 0.3314912969415838,
"loss_toxic": 0.19506627795371143
},
{
"loss": 3.0410762049935083,
"loss_size": 0.26710020818493585,
"loss_pdi": 0.8061394041234796,
"loss_ee": 0.86360948194157,
"loss_delivery": 0.6474485844373703,
"loss_biodist": 0.2775672037493099,
"loss_toxic": 0.17921125888824463
},
{
"loss": 2.856840046969327,
"loss_size": 0.23434289409355682,
"loss_pdi": 0.7359850352460687,
"loss_ee": 0.8523386337540366,
"loss_delivery": 0.6672194654291327,
"loss_biodist": 0.24257711659778247,
"loss_toxic": 0.12437698854641481
},
{
"loss": 2.753721583973278,
"loss_size": 0.22194186733527618,
"loss_pdi": 0.7571314085613597,
"loss_ee": 0.8207993832501498,
"loss_delivery": 0.6183277395638552,
"loss_biodist": 0.20758610421961005,
"loss_toxic": 0.1279351504688913
},
{
"loss": 2.656247529116544,
"loss_size": 0.23931451277299362,
"loss_pdi": 0.7019712057980624,
"loss_ee": 0.8223658420822837,
"loss_delivery": 0.6005800881169059,
"loss_biodist": 0.20160710269754584,
"loss_toxic": 0.09040880711241202
},
{
"loss": 2.5767899426546963,
"loss_size": 0.19733469526876102,
"loss_pdi": 0.6646544608202848,
"loss_ee": 0.7930623184550892,
"loss_delivery": 0.6240379756147211,
"loss_biodist": 0.19077409600669687,
"loss_toxic": 0.10692638869990002
},
{
"loss": 2.48127299005335,
"loss_size": 0.21488605371930383,
"loss_pdi": 0.6530601653185758,
"loss_ee": 0.7582464814186096,
"loss_delivery": 0.5737349580634724,
"loss_biodist": 0.16496530107476495,
"loss_toxic": 0.11637999422170899
},
{
"loss": 2.511795390735973,
"loss_size": 0.23083434728058902,
"loss_pdi": 0.6640139438889243,
"loss_ee": 0.7850931991230358,
"loss_delivery": 0.5663588629527525,
"loss_biodist": 0.16403887217695062,
"loss_toxic": 0.10145619206807831
},
{
"loss": 2.4520826556465845,
"loss_size": 0.2435093102130023,
"loss_pdi": 0.6493249454281547,
"loss_ee": 0.7549291469834067,
"loss_delivery": 0.5565172542225231,
"loss_biodist": 0.1651345667513934,
"loss_toxic": 0.08266745169054378
},
{
"loss": 2.528990225358443,
"loss_size": 0.2728923593055118,
"loss_pdi": 0.648305053060705,
"loss_ee": 0.7451089945706454,
"loss_delivery": 0.5968177616596222,
"loss_biodist": 0.158570219847289,
"loss_toxic": 0.10729587349024686
},
{
"loss": 2.4473495700142602,
"loss_size": 0.26256248219446704,
"loss_pdi": 0.6349984976378354,
"loss_ee": 0.7601472193544562,
"loss_delivery": 0.5579715635288846,
"loss_biodist": 0.1570260843092745,
"loss_toxic": 0.0746436957269907
},
{
"loss": 2.382858254692771,
"loss_size": 0.22761954638091,
"loss_pdi": 0.6203812062740326,
"loss_ee": 0.7453795942393217,
"loss_delivery": 0.5487408299337734,
"loss_biodist": 0.15750546685673975,
"loss_toxic": 0.08323164876889098
},
{
"loss": 2.417541742324829,
"loss_size": 0.23440214517441663,
"loss_pdi": 0.6343399882316589,
"loss_ee": 0.7542760643092069,
"loss_delivery": 0.5531045618382368,
"loss_biodist": 0.16038942404768683,
"loss_toxic": 0.08102951266548851
},
{
"loss": 2.364789128303528,
"loss_size": 0.2361523915420879,
"loss_pdi": 0.6382588039744984,
"loss_ee": 0.7520397088744424,
"loss_delivery": 0.5134848952293396,
"loss_biodist": 0.15789563005620783,
"loss_toxic": 0.0669576974416321
},
{
"loss": 2.3840558528900146,
"loss_size": 0.19821467182853006,
"loss_pdi": 0.6134677800265226,
"loss_ee": 0.750839504328641,
"loss_delivery": 0.5778178457509388,
"loss_biodist": 0.15469309890812094,
"loss_toxic": 0.0890229269862175
}
],
"val": []
}

3
models/nested_cv/20260302_110648/outer_fold_3/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:f4f17646160876093d7c18fa831016f0558a06aae982be2d81efcce571c94909
size 28583340

BIN
models/nested_cv/20260302_110648/outer_fold_3/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

1
models/nested_cv/20260302_110648/outer_fold_3/splits.json Normal file
View File

@ -0,0 +1 @@
{"outer_train_idx": [0, 1, 2, 4, 5, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 20, 21, 22, 23, 24, 25, 27, 28, 29, 30, 31, 32, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 45, 46, 47, 51, 52, 53, 54, 55, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 73, 74, 75, 76, 77, 78, 79, 81, 82, 83, 84, 85, 86, 87, 89, 90, 91, 92, 93, 95, 96, 97, 98, 99, 100, 102, 104, 105, 106, 109, 110, 111, 112, 113, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 127, 129, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 146, 147, 148, 150, 151, 152, 153, 154, 155, 156, 158, 159, 160, 161, 162, 163, 164, 165, 166, 168, 169, 170, 172, 173, 174, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 189, 190, 191, 192, 193, 194, 195, 198, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 212, 213, 214, 215, 216, 217, 218, 219, 221, 223, 224, 226, 227, 228, 230, 231, 233, 234, 235, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 262, 263, 264, 265, 266, 267, 268, 269, 270, 272, 273, 274, 275, 276, 277, 278, 279, 280, 282, 284, 286, 288, 289, 290, 291, 292, 293, 294, 295, 297, 298, 299, 301, 302, 304, 305, 306, 307, 308, 309, 310, 312, 314, 315, 316, 317, 319, 320, 321, 325, 326, 327, 328, 331, 332, 334, 336, 340, 341, 343, 344, 346, 347, 348, 350, 352, 353, 357, 359, 360, 361, 362, 363, 364, 366, 367, 368, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 382, 383, 384, 385, 386, 387, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 400, 401, 402, 403, 404, 406, 407, 410, 411, 412, 414, 415, 416, 418, 419], "outer_test_idx": [3, 6, 13, 18, 19, 26, 33, 44, 48, 49, 50, 56, 57, 72, 80, 88, 94, 101, 103, 107, 108, 114, 126, 128, 130, 145, 149, 157, 167, 171, 175, 188, 196, 197, 199, 211, 220, 222, 225, 229, 232, 236, 250, 260, 261, 271, 281, 283, 285, 287, 296, 300, 303, 311, 313, 318, 322, 323, 324, 329, 330, 333, 335, 337, 338, 339, 342, 345, 349, 351, 354, 355, 356, 358, 365, 369, 381, 388, 399, 405, 408, 409, 413, 417]}

42
models/nested_cv/20260302_110648/outer_fold_3/test_metrics.json Normal file
View File

@ -0,0 +1,42 @@
{
"size": {
"n_samples": 83,
"mse": 0.4172014495115836,
"rmse": 0.6459113325461813,
"mae": 0.31643760635192136,
"r2": -0.28019803113261177
},
"delivery": {
"n_samples": 59,
"mse": 0.6657579552491054,
"rmse": 0.8159399213478314,
"mae": 0.5076249049723907,
"r2": 0.3528041681920817
},
"pdi": {
"n_samples": 84,
"accuracy": 0.7261904761904762,
"precision": 0.5178283873936048,
"recall": 0.7818740399385561,
"f1": 0.5410135841170324
},
"ee": {
"n_samples": 84,
"accuracy": 0.6666666666666666,
"precision": 0.5903252773977808,
"recall": 0.6201608848667672,
"f1": 0.59879647539222
},
"toxic": {
"n_samples": 60,
"accuracy": 0.9333333333333333,
"precision": 0.7142857142857143,
"recall": 0.9649122807017544,
"f1": 0.7818181818181817
},
"biodist": {
"n_samples": 60,
"kl_divergence": 0.1549686979086472,
"js_divergence": 0.04090113862268173
}
}

11
models/nested_cv/20260302_110648/outer_fold_4/best_params.json Normal file
View File

@ -0,0 +1,11 @@
{
"dropout": 0.2644252830630203,
"lr": 0.00047786312466235084,
"weight_decay": 0.00014812429727941733,
"backbone_lr_ratio": 0.4924030302991967,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
}

1
models/nested_cv/20260302_110648/outer_fold_4/epoch_mean.json Normal file
View File

@ -0,0 +1 @@
{"epoch_mean": 14}

131
models/nested_cv/20260302_110648/outer_fold_4/history.json Normal file
View File

@ -0,0 +1,131 @@
{
"train": [
{
"loss": 13.525793075561523,
"loss_size": 8.348952496593649,
"loss_pdi": 1.4388561032035134,
"loss_ee": 1.0827805128964512,
"loss_delivery": 0.9820561896670948,
"loss_biodist": 1.0800667134198276,
"loss_toxic": 0.5930807969786904
},
{
"loss": 5.285936225544322,
"loss_size": 0.6155025146224282,
"loss_pdi": 1.270021915435791,
"loss_ee": 1.0845766230063005,
"loss_delivery": 0.9430169036442583,
"loss_biodist": 0.7335741303183816,
"loss_toxic": 0.6392440768805417
},
{
"loss": 4.40376184203408,
"loss_size": 0.5600908994674683,
"loss_pdi": 1.059586768800562,
"loss_ee": 1.039989872412248,
"loss_delivery": 0.9359676783735101,
"loss_biodist": 0.5028434043580835,
"loss_toxic": 0.3052830425175754
},
{
"loss": 3.647651043805209,
"loss_size": 0.38391653109680524,
"loss_pdi": 0.9243402101776816,
"loss_ee": 0.9893178723075173,
"loss_delivery": 0.8463814637877725,
"loss_biodist": 0.349913318048824,
"loss_toxic": 0.1537816429680044
},
{
"loss": 3.3332926360043613,
"loss_size": 0.3561195162209598,
"loss_pdi": 0.8763764825734225,
"loss_ee": 0.9291761300780557,
"loss_delivery": 0.7829304906454954,
"loss_biodist": 0.2742909111759879,
"loss_toxic": 0.11439906848086552
},
{
"loss": 3.0087678865952925,
"loss_size": 0.30534919419071893,
"loss_pdi": 0.784204824404283,
"loss_ee": 0.8751094774766401,
"loss_delivery": 0.7525362399491397,
"loss_biodist": 0.20358707823536612,
"loss_toxic": 0.0879810547286814
},
{
"loss": 2.932733817534013,
"loss_size": 0.3680957718328996,
"loss_pdi": 0.7639480287378485,
"loss_ee": 0.850922167301178,
"loss_delivery": 0.6120568744160912,
"loss_biodist": 0.19816767356612466,
"loss_toxic": 0.1395433105697686
},
{
"loss": 2.7500832731073555,
"loss_size": 0.3316680734807795,
"loss_pdi": 0.7082917446439917,
"loss_ee": 0.8220180489800193,
"loss_delivery": 0.6263827817006544,
"loss_biodist": 0.17620120062069458,
"loss_toxic": 0.08552140132947401
},
{
"loss": 2.755212198604237,
"loss_size": 0.3619026853279634,
"loss_pdi": 0.679839012297717,
"loss_ee": 0.8076501109383323,
"loss_delivery": 0.6478644026951357,
"loss_biodist": 0.18192330544645136,
"loss_toxic": 0.07603263372386043
},
{
"loss": 2.5111556486649946,
"loss_size": 0.329572932286696,
"loss_pdi": 0.6627143187956377,
"loss_ee": 0.7828090245073492,
"loss_delivery": 0.5216223743151535,
"loss_biodist": 0.15503901852802796,
"loss_toxic": 0.05939798785204237
},
{
"loss": 2.4764873547987505,
"loss_size": 0.3141739558089863,
"loss_pdi": 0.617889791727066,
"loss_ee": 0.7782617102969777,
"loss_delivery": 0.5555136704986746,
"loss_biodist": 0.15500380098819733,
"loss_toxic": 0.05564440003680912
},
{
"loss": 2.3972831856120718,
"loss_size": 0.32312248105352576,
"loss_pdi": 0.58486546440558,
"loss_ee": 0.7550333575768904,
"loss_delivery": 0.5430025959556753,
"loss_biodist": 0.1466368626464497,
"loss_toxic": 0.044622470032085075
},
{
"loss": 2.336688507686962,
"loss_size": 0.2918369160457091,
"loss_pdi": 0.6055164201693102,
"loss_ee": 0.7336211692203175,
"loss_delivery": 0.5100014033642682,
"loss_biodist": 0.1525442356413061,
"loss_toxic": 0.04316838434897363
},
{
"loss": 2.360760721293363,
"loss_size": 0.26587091250853107,
"loss_pdi": 0.6070473437959497,
"loss_ee": 0.74156653881073,
"loss_delivery": 0.5466614920984615,
"loss_biodist": 0.13190614838491788,
"loss_toxic": 0.06770833530886607
}
],
"val": []
}

3
models/nested_cv/20260302_110648/outer_fold_4/model.pt Normal file
View File

@ -0,0 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:0436290e3d8c55d46b79bcfad202a1461df7127b85eef513730a68b8c7c81195
size 28583340

BIN
models/nested_cv/20260302_110648/outer_fold_4/optuna_study.sqlite3 Normal file
View File

Binary file not shown.

1
models/nested_cv/20260302_110648/outer_fold_4/splits.json Normal file
View File

@ -0,0 +1 @@
{"outer_train_idx": [1, 2, 3, 4, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 23, 25, 26, 28, 29, 31, 33, 34, 35, 37, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 54, 56, 57, 59, 60, 62, 63, 64, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 77, 78, 79, 80, 81, 82, 83, 84, 85, 87, 88, 89, 90, 91, 92, 93, 94, 96, 97, 98, 99, 101, 102, 103, 104, 105, 107, 108, 110, 111, 112, 113, 114, 116, 117, 119, 120, 121, 122, 123, 124, 126, 127, 128, 130, 132, 133, 134, 135, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 149, 152, 154, 155, 157, 160, 161, 162, 163, 164, 165, 166, 167, 169, 170, 171, 173, 174, 175, 176, 177, 178, 180, 181, 182, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 203, 205, 206, 207, 208, 209, 211, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 229, 230, 231, 232, 234, 235, 236, 238, 239, 240, 241, 243, 244, 245, 246, 247, 248, 249, 250, 251, 253, 254, 257, 258, 260, 261, 262, 263, 264, 265, 266, 267, 270, 271, 272, 273, 277, 278, 279, 280, 281, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 298, 299, 300, 301, 302, 303, 304, 305, 306, 309, 311, 312, 313, 314, 315, 316, 318, 319, 320, 322, 323, 324, 325, 326, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 341, 342, 343, 345, 346, 347, 349, 350, 351, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 365, 367, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 381, 383, 384, 385, 386, 388, 390, 391, 392, 393, 394, 395, 396, 397, 399, 400, 401, 402, 403, 405, 406, 407, 408, 409, 410, 411, 413, 415, 416, 417, 418, 419], "outer_test_idx": [0, 5, 11, 21, 24, 27, 30, 32, 36, 38, 39, 40, 47, 55, 58, 61, 65, 76, 86, 95, 100, 106, 109, 115, 118, 125, 129, 131, 136, 148, 150, 151, 153, 156, 158, 159, 168, 172, 179, 183, 184, 185, 202, 204, 210, 212, 213, 228, 233, 237, 242, 252, 255, 256, 259, 268, 269, 274, 275, 276, 282, 297, 307, 308, 310, 317, 321, 327, 340, 344, 348, 352, 364, 366, 368, 379, 380, 382, 387, 389, 398, 404, 412, 414]}

42
models/nested_cv/20260302_110648/outer_fold_4/test_metrics.json Normal file
View File

@ -0,0 +1,42 @@
{
"size": {
"n_samples": 84,
"mse": 0.11630157603965702,
"rmse": 0.3410301688115833,
"mae": 0.22757892097745622,
"r2": 0.15569737793159788
},
"delivery": {
"n_samples": 58,
"mse": 0.8730690733744573,
"rmse": 0.934381652952613,
"mae": 0.5687187765564384,
"r2": 0.155756618760172
},
"pdi": {
"n_samples": 84,
"accuracy": 0.7976190476190477,
"precision": 0.4772893772893773,
"recall": 0.5948540706605223,
"f1": 0.48832958380202474
},
"ee": {
"n_samples": 84,
"accuracy": 0.6785714285714286,
"precision": 0.6349206349206349,
"recall": 0.6696581196581196,
"f1": 0.6393311036789296
},
"toxic": {
"n_samples": 59,
"accuracy": 0.9830508474576272,
"precision": 0.875,
"recall": 0.9910714285714286,
"f1": 0.9240669240669239
},
"biodist": {
"n_samples": 58,
"kl_divergence": 0.16969217947848778,
"js_divergence": 0.0395276095457105
}
}

60
models/nested_cv/20260302_110648/strata_info.json Normal file
View File

@ -0,0 +1,60 @@
{
"original_strata_counts": {
"T0|P0|E0": "5",
"T0|P0|E1": "58",
"T0|P0|E2": "169",
"T0|P1|E0": "1",
"T0|P1|E1": "17",
"T0|P1|E2": "32",
"T0|P2|E2": "3",
"T1|P0|E2": "9",
"T1|P1|E2": "5",
"TNA|P0|E0": "28",
"TNA|P0|E1": "21",
"TNA|P0|E2": "20",
"TNA|P1|E0": "29",
"TNA|P1|E1": "7",
"TNA|P1|E2": "14",
"TNA|P2|E2": "1",
"TNA|P3|E0": "1"
},
"rare_strata": [
"T0|P1|E0",
"T0|P2|E2",
"TNA|P2|E2",
"TNA|P3|E0"
],
"final_strata": [
"RARE",
"T0|P0|E0",
"T0|P0|E1",
"T0|P0|E2",
"T0|P1|E1",
"T0|P1|E2",
"T1|P0|E2",
"T1|P1|E2",
"TNA|P0|E0",
"TNA|P0|E1",
"TNA|P0|E2",
"TNA|P1|E0",
"TNA|P1|E1",
"TNA|P1|E2"
],
"final_strata_counts": {
"RARE": "6",
"T0|P0|E0": "5",
"T0|P0|E1": "58",
"T0|P0|E2": "169",
"T0|P1|E1": "17",
"T0|P1|E2": "32",
"T1|P0|E2": "9",
"T1|P1|E2": "5",
"TNA|P0|E0": "28",
"TNA|P0|E1": "21",
"TNA|P0|E2": "20",
"TNA|P1|E0": "29",
"TNA|P1|E1": "7",
"TNA|P1|E2": "14"
},
"n_rare_merged": "6"
}

347
models/nested_cv/20260302_110648/summary.json Normal file
View File

@ -0,0 +1,347 @@
{
"fold_results": [
{
"fold": 0,
"best_params": {
"dropout": 0.13138363142855383,
"lr": 0.0003183893957684731,
"weight_decay": 0.09324304909602012,
"backbone_lr_ratio": 0.35598913444921026,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
},
"epoch_mean": 14,
"test_metrics": {
"size": {
"n_samples": 83,
"mse": 0.3019449796801696,
"rmse": 0.5494952044196287,
"mae": 0.2869321725454675,
"r2": -0.002565673822219283
},
"delivery": {
"n_samples": 58,
"mse": 0.4861564349157676,
"rmse": 0.6972491914056033,
"mae": 0.5075679545387112,
"r2": 0.3820658346383613
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6428571428571429,
"precision": 0.3838387806411062,
"recall": 0.5765027322404371,
"f1": 0.4081896551724138
},
"ee": {
"n_samples": 84,
"accuracy": 0.7261904761904762,
"precision": 0.6957516339869282,
"recall": 0.7652380952380953,
"f1": 0.7042577030812325
},
"toxic": {
"n_samples": 58,
"accuracy": 0.9310344827586207,
"precision": 0.6157407407407407,
"recall": 0.7232142857142857,
"f1": 0.6484848484848484
},
"biodist": {
"n_samples": 58,
"kl_divergence": 0.1773200742051057,
"js_divergence": 0.038189943291577606
}
}
},
{
"fold": 1,
"best_params": {
"dropout": 0.11160552976974417,
"lr": 0.0002934246482004709,
"weight_decay": 0.000380014417451246,
"backbone_lr_ratio": 0.40187800461703077,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
},
"epoch_mean": 11,
"test_metrics": {
"size": {
"n_samples": 84,
"mse": 0.06851485629954368,
"rmse": 0.2617534265287537,
"mae": 0.19058226403735934,
"r2": -0.1350613967945693
},
"delivery": {
"n_samples": 61,
"mse": 0.8536548404567659,
"rmse": 0.9239344351504417,
"mae": 0.5235513564138139,
"r2": 0.3538448248397684
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6309523809523809,
"precision": 0.30528846153846156,
"recall": 0.28174603174603174,
"f1": 0.291304347826087
},
"ee": {
"n_samples": 84,
"accuracy": 0.5714285714285714,
"precision": 0.5202020202020202,
"recall": 0.5292564578278864,
"f1": 0.5119174942704355
},
"toxic": {
"n_samples": 61,
"accuracy": 0.9508196721311475,
"precision": 0.75,
"recall": 0.9741379310344828,
"f1": 0.8200589970501475
},
"biodist": {
"n_samples": 61,
"kl_divergence": 0.17284391250731643,
"js_divergence": 0.04385579372373865
}
}
},
{
"fold": 2,
"best_params": {
"dropout": 0.18117503720006686,
"lr": 8.135394049241399e-05,
"weight_decay": 0.015076469897649124,
"backbone_lr_ratio": 0.9586175198423679,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
},
"epoch_mean": 25,
"test_metrics": {
"size": {
"n_samples": 84,
"mse": 0.09662744334561678,
"rmse": 0.3108495509818484,
"mae": 0.23867071242559523,
"r2": -0.03533227905101599
},
"delivery": {
"n_samples": 60,
"mse": 0.6406059342358218,
"rmse": 0.8003786193020287,
"mae": 0.5084985921236996,
"r2": 0.147242469212558
},
"pdi": {
"n_samples": 84,
"accuracy": 0.6071428571428571,
"precision": 0.3536231884057971,
"recall": 0.5382104454685099,
"f1": 0.37173202614379086
},
"ee": {
"n_samples": 84,
"accuracy": 0.6547619047619048,
"precision": 0.6023391812865497,
"recall": 0.6626984126984127,
"f1": 0.615613004906073
},
"toxic": {
"n_samples": 61,
"accuracy": 0.9508196721311475,
"precision": 0.75,
"recall": 0.9741379310344828,
"f1": 0.8200589970501475
},
"biodist": {
"n_samples": 60,
"kl_divergence": 0.14159162897750524,
"js_divergence": 0.03735438196115702
}
}
},
{
"fold": 3,
"best_params": {
"dropout": 0.1463802845991778,
"lr": 0.00017979738268552602,
"weight_decay": 0.026590603512062855,
"backbone_lr_ratio": 0.19962036354162335,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
},
"epoch_mean": 21,
"test_metrics": {
"size": {
"n_samples": 83,
"mse": 0.4172014495115836,
"rmse": 0.6459113325461813,
"mae": 0.31643760635192136,
"r2": -0.28019803113261177
},
"delivery": {
"n_samples": 59,
"mse": 0.6657579552491054,
"rmse": 0.8159399213478314,
"mae": 0.5076249049723907,
"r2": 0.3528041681920817
},
"pdi": {
"n_samples": 84,
"accuracy": 0.7261904761904762,
"precision": 0.5178283873936048,
"recall": 0.7818740399385561,
"f1": 0.5410135841170324
},
"ee": {
"n_samples": 84,
"accuracy": 0.6666666666666666,
"precision": 0.5903252773977808,
"recall": 0.6201608848667672,
"f1": 0.59879647539222
},
"toxic": {
"n_samples": 60,
"accuracy": 0.9333333333333333,
"precision": 0.7142857142857143,
"recall": 0.9649122807017544,
"f1": 0.7818181818181817
},
"biodist": {
"n_samples": 60,
"kl_divergence": 0.1549686979086472,
"js_divergence": 0.04090113862268173
}
}
},
{
"fold": 4,
"best_params": {
"dropout": 0.2644252830630203,
"lr": 0.00047786312466235084,
"weight_decay": 0.00014812429727941733,
"backbone_lr_ratio": 0.4924030302991967,
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128
},
"epoch_mean": 14,
"test_metrics": {
"size": {
"n_samples": 84,
"mse": 0.11630157603965702,
"rmse": 0.3410301688115833,
"mae": 0.22757892097745622,
"r2": 0.15569737793159788
},
"delivery": {
"n_samples": 58,
"mse": 0.8730690733744573,
"rmse": 0.934381652952613,
"mae": 0.5687187765564384,
"r2": 0.155756618760172
},
"pdi": {
"n_samples": 84,
"accuracy": 0.7976190476190477,
"precision": 0.4772893772893773,
"recall": 0.5948540706605223,
"f1": 0.48832958380202474
},
"ee": {
"n_samples": 84,
"accuracy": 0.6785714285714286,
"precision": 0.6349206349206349,
"recall": 0.6696581196581196,
"f1": 0.6393311036789296
},
"toxic": {
"n_samples": 59,
"accuracy": 0.9830508474576272,
"precision": 0.875,
"recall": 0.9910714285714286,
"f1": 0.9240669240669239
},
"biodist": {
"n_samples": 58,
"kl_divergence": 0.16969217947848778,
"js_divergence": 0.0395276095457105
}
}
}
],
"summary_stats": {
"size": {
"mse_mean": 0.20011806097531415,
"mse_std": 0.13605060346546968,
"rmse_mean": 0.421807936657599,
"rmse_std": 0.1489836418804863,
"mae_mean": 0.2520403352675599,
"mae_std": 0.044539086104422025,
"r2_mean": -0.05949200057376369,
"r2_std": 0.14460473921225706
},
"delivery": {
"mse_mean": 0.7038488476463836,
"mse_std": 0.14416510605421703,
"rmse_mean": 0.8343767640317037,
"rmse_std": 0.08754577825552946,
"mae_mean": 0.5231923169210108,
"mae_std": 0.02355910863909835,
"r2_mean": 0.2783427831285883,
"r2_std": 0.10413278790666436
},
"pdi": {
"accuracy_mean": 0.680952380952381,
"accuracy_std": 0.07079080355865956,
"precision_mean": 0.40757363905366945,
"precision_std": 0.07867991593480861,
"recall_mean": 0.5546374640108114,
"recall_std": 0.16029442135411243,
"f1_mean": 0.42011383941226976,
"f1_std": 0.08757283505739442
},
"ee": {
"accuracy_mean": 0.6595238095238095,
"accuracy_std": 0.05028264781414971,
"precision_mean": 0.6087077495587827,
"precision_std": 0.05740294635102721,
"recall_mean": 0.6494023940578562,
"recall_std": 0.07654423564390637,
"f1_mean": 0.6139831562657782,
"f1_std": 0.06235816431212298
},
"toxic": {
"accuracy_mean": 0.9498116015623752,
"accuracy_std": 0.018606414993903777,
"precision_mean": 0.741005291005291,
"precision_std": 0.08309215961982111,
"recall_mean": 0.9254947714112868,
"recall_std": 0.1014926074677688,
"f1_mean": 0.7988975896940499,
"f1_std": 0.08885794447474714
},
"biodist": {
"kl_divergence_mean": 0.16328329861541246,
"kl_divergence_std": 0.013184621932051109,
"js_divergence_mean": 0.0399657734289731,
"js_divergence_std": 0.0022878851196224824
}
}
}

21
models/pretrain_cv/config.json
View File

@ -1,21 +0,0 @@
{
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,
"epochs": 50,
"patience": 10
}

68
models/pretrain_cv/cv_results.json
View File

@ -1,68 +0,0 @@
{
"fold_results": [
{
"fold_idx": 0,
"best_val_loss": 0.8423525478929029,
"best_val_rmse": 0.9331341268749274,
"best_val_r2": 0.2524544731269053,
"epochs_trained": 19
},
{
"fold_idx": 1,
"best_val_loss": 0.7009093638175043,
"best_val_rmse": 0.888277234295553,
"best_val_r2": 0.19871749006650596,
"epochs_trained": 16
},
{
"fold_idx": 2,
"best_val_loss": 0.7235820254347072,
"best_val_rmse": 0.8821482466127635,
"best_val_r2": 0.25251501039626645,
"epochs_trained": 26
},
{
"fold_idx": 3,
"best_val_loss": 0.7233524476227008,
"best_val_rmse": 0.8598248435346856,
"best_val_r2": 0.2173208126626488,
"epochs_trained": 11
},
{
"fold_idx": 4,
"best_val_loss": 0.7125106603565553,
"best_val_rmse": 0.9044179837028969,
"best_val_r2": 0.05955105566092167,
"epochs_trained": 11
}
],
"summary": {
"val_loss_mean": 0.7405414090248741,
"val_loss_std": 0.051584902755892316,
"val_rmse_mean": 0.8935604870041655,
"val_rmse_std": 0.024413946167786103,
"val_r2_mean": 0.19611176838264963,
"val_r2_std": 0.07136002759441169
},
"config": {
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/Users/ryde/Documents/workspaces/\u8102\u8d28\u5206\u5b50\u836f\u7269\u9012\u9001\u6027\u80fd\u9884\u6d4b/\u6700\u65b0\u6574\u7406/lnp-ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,
"epochs": 50,
"patience": 10
}
}

154
models/pretrain_cv/fold_0/history.json
View File

@ -1,154 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.7841362829904129,
"val_loss": 0.9230800325498075,
"val_rmse": 0.9607705443260125,
"val_r2": 0.20751899565844845,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6463805462366321,
"val_loss": 0.9147881584284676,
"val_rmse": 0.9564455868655657,
"val_r2": 0.2146377239324061,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.5832159742587586,
"val_loss": 0.8564491166460212,
"val_rmse": 0.9254453497069719,
"val_r2": 0.2647228727252957,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5554495169353261,
"val_loss": 0.9521924139543092,
"val_rmse": 0.9758034723689635,
"val_r2": 0.18252548972094385,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5284749799126208,
"val_loss": 0.9002334602240055,
"val_rmse": 0.9488063310427656,
"val_r2": 0.22713320447964735,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.5008455182478028,
"val_loss": 0.8869625280360692,
"val_rmse": 0.9417868917406855,
"val_r2": 0.23852651728338659,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.4812185961924912,
"val_loss": 0.8656982819227316,
"val_rmse": 0.9304290898141719,
"val_r2": 0.25678226981933505,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.46716415395603483,
"val_loss": 0.8974583646500499,
"val_rmse": 0.9473427898099364,
"val_r2": 0.22951567180333565,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.44227657012969945,
"val_loss": 0.8423525478929029,
"val_rmse": 0.917797665041863,
"val_r2": 0.2768250098825846,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4192214831283541,
"val_loss": 0.8834660291599854,
"val_rmse": 0.9399287338143215,
"val_r2": 0.24152834743071827,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.4261854484762579,
"val_loss": 0.8901423802745356,
"val_rmse": 0.9434735654804721,
"val_r2": 0.23579658456782115,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.40934500416213515,
"val_loss": 0.8902992367456848,
"val_rmse": 0.9435566978740579,
"val_r2": 0.2356619059496775,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.3993083212922134,
"val_loss": 0.8952986713233702,
"val_rmse": 0.946202241268488,
"val_r2": 0.23136979638836497,
"lr": 0.0001
},
{
"epoch": 14,
"train_loss": 0.38611710345412054,
"val_loss": 0.898042505591281,
"val_rmse": 0.9476510417548493,
"val_r2": 0.22901418082171254,
"lr": 0.0001
},
{
"epoch": 15,
"train_loss": 0.3662278820512592,
"val_loss": 0.8985377061208856,
"val_rmse": 0.9479122944969771,
"val_r2": 0.2285890244824833,
"lr": 0.0001
},
{
"epoch": 16,
"train_loss": 0.33336883667983097,
"val_loss": 0.8594161927771942,
"val_rmse": 0.9270470292726928,
"val_r2": 0.26217556409941023,
"lr": 5e-05
},
{
"epoch": 17,
"train_loss": 0.33174229304183017,
"val_loss": 0.8942263270711439,
"val_rmse": 0.945635409387207,
"val_r2": 0.23229043171319064,
"lr": 5e-05
},
{
"epoch": 18,
"train_loss": 0.3200935872264761,
"val_loss": 0.8843722421096231,
"val_rmse": 0.9404106786278892,
"val_r2": 0.24075034122444328,
"lr": 5e-05
},
{
"epoch": 19,
"train_loss": 0.3140528901624022,
"val_loss": 0.8707393039336969,
"val_rmse": 0.9331341268749274,
"val_r2": 0.2524544731269053,
"lr": 5e-05
}
]

3
models/pretrain_cv/fold_0/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:df9ec76eefc7ac3c9b161120d056d987082878b8c06990c0ef56928a54d1df3c
size 28584172

130
models/pretrain_cv/fold_1/history.json
View File

@ -1,130 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.7586579631889938,
"val_loss": 0.7181247283430661,
"val_rmse": 0.8474223956247073,
"val_r2": 0.27072978816447013,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6169086206378913,
"val_loss": 0.7122436411609591,
"val_rmse": 0.8439452896464879,
"val_r2": 0.27670212861312427,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.5716009976577638,
"val_loss": 0.724399374180903,
"val_rmse": 0.8511165408178202,
"val_r2": 0.2643577544134178,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5406081575331337,
"val_loss": 0.8086859301147815,
"val_rmse": 0.8992696715048705,
"val_r2": 0.17876302728821758,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5032305184360722,
"val_loss": 0.7551608490501026,
"val_rmse": 0.8689999128971181,
"val_r2": 0.23311884509134373,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.49779197957664073,
"val_loss": 0.7009093638175043,
"val_rmse": 0.8372033005770025,
"val_r2": 0.2882123252930564,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.4720957023516007,
"val_loss": 0.7939711763762837,
"val_rmse": 0.8910506016905562,
"val_r2": 0.1937061718828037,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.45880254612337634,
"val_loss": 0.7781202286020521,
"val_rmse": 0.8821112329914439,
"val_r2": 0.209803130396238,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.43299420961863133,
"val_loss": 0.7305147618332145,
"val_rmse": 0.8547015607274253,
"val_r2": 0.25814744997562133,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4271428178197404,
"val_loss": 0.736324011356838,
"val_rmse": 0.8580932378454483,
"val_r2": 0.25224804192225836,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.4049153788182662,
"val_loss": 0.7328011674777642,
"val_rmse": 0.8560380622891226,
"val_r2": 0.2558255581383374,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.4011265030265379,
"val_loss": 0.8308254960889787,
"val_rmse": 0.9114962980441127,
"val_r2": 0.15627985591441118,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.36400350090994316,
"val_loss": 0.7314743397036573,
"val_rmse": 0.8552627260066816,
"val_r2": 0.25717298455584947,
"lr": 5e-05
},
{
"epoch": 14,
"train_loss": 0.35224626399225445,
"val_loss": 0.7428758944520272,
"val_rmse": 0.8619024879725893,
"val_r2": 0.24559446076977343,
"lr": 5e-05
},
{
"epoch": 15,
"train_loss": 0.33604996105846857,
"val_loss": 0.7853316709722159,
"val_rmse": 0.8861894055728078,
"val_r2": 0.20247977173777976,
"lr": 5e-05
},
{
"epoch": 16,
"train_loss": 0.3375160908226994,
"val_loss": 0.7890364486366602,
"val_rmse": 0.888277234295553,
"val_r2": 0.19871749006650596,
"lr": 5e-05
}
]

3
models/pretrain_cv/fold_1/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:cf2db65c7e0536389eddc67767c87372464ddde580f69a7654624e5a3810240f
size 28584172

210
models/pretrain_cv/fold_2/history.json
View File

@ -1,210 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.791098108242938,
"val_loss": 0.7719947347075529,
"val_rmse": 0.878632305711343,
"val_r2": 0.25846157477201237,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6658925409901272,
"val_loss": 0.7617311492273446,
"val_rmse": 0.8727721145733892,
"val_r2": 0.26832022703332314,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6122674057266099,
"val_loss": 0.8769170071679075,
"val_rmse": 0.9364384705484738,
"val_r2": 0.15767862930010346,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5742751938678995,
"val_loss": 0.7367407811068618,
"val_rmse": 0.8583360495407089,
"val_r2": 0.2923247102058987,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5531474925106927,
"val_loss": 0.7950987294231336,
"val_rmse": 0.8916830851722821,
"val_r2": 0.23626906492194255,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.527079365248884,
"val_loss": 0.802677319898029,
"val_rmse": 0.895922608061829,
"val_r2": 0.22898945616093758,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5123950171866232,
"val_loss": 0.782698355759563,
"val_rmse": 0.88470241000697,
"val_r2": 0.24818022257968875,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.4904004101283092,
"val_loss": 0.7598537935566331,
"val_rmse": 0.871695932346191,
"val_r2": 0.2701235277693791,
"lr": 0.0001
},
{
"epoch": 9,
"train_loss": 0.4724999822167431,
"val_loss": 0.7330814787232346,
"val_rmse": 0.856201763512417,
"val_r2": 0.295839659096092,
"lr": 0.0001
},
{
"epoch": 10,
"train_loss": 0.4588321148588464,
"val_loss": 0.8768221832463515,
"val_rmse": 0.9363878373732571,
"val_r2": 0.15776971537541384,
"lr": 0.0001
},
{
"epoch": 11,
"train_loss": 0.4419767470898412,
"val_loss": 0.8529776517416487,
"val_rmse": 0.923567892947146,
"val_r2": 0.18067354347355968,
"lr": 0.0001
},
{
"epoch": 12,
"train_loss": 0.44027366810112756,
"val_loss": 0.7568119836709927,
"val_rmse": 0.8699494234122945,
"val_r2": 0.2730453235865089,
"lr": 0.0001
},
{
"epoch": 13,
"train_loss": 0.42930884333119396,
"val_loss": 0.788217492834872,
"val_rmse": 0.8878161341676009,
"val_r2": 0.24287882653794168,
"lr": 0.0001
},
{
"epoch": 14,
"train_loss": 0.4194908241938084,
"val_loss": 0.7534916236775767,
"val_rmse": 0.8680389443471926,
"val_r2": 0.27623471979749215,
"lr": 0.0001
},
{
"epoch": 15,
"train_loss": 0.4176158948011587,
"val_loss": 0.8106847968517442,
"val_rmse": 0.9003803645851803,
"val_r2": 0.22129788153136576,
"lr": 0.0001
},
{
"epoch": 16,
"train_loss": 0.38479953538329265,
"val_loss": 0.7235820254347072,
"val_rmse": 0.8506362402435862,
"val_r2": 0.30496433887728125,
"lr": 5e-05
},
{
"epoch": 17,
"train_loss": 0.36291458054036185,
"val_loss": 0.7698690443721301,
"val_rmse": 0.8774218234638004,
"val_r2": 0.2605033862868045,
"lr": 5e-05
},
{
"epoch": 18,
"train_loss": 0.35190441592072863,
"val_loss": 0.7518946720093931,
"val_rmse": 0.8671186052451901,
"val_r2": 0.27776865181926147,
"lr": 5e-05
},
{
"epoch": 19,
"train_loss": 0.3459884363256904,
"val_loss": 0.7640664695741921,
"val_rmse": 0.8741089628969817,
"val_r2": 0.26607704353364603,
"lr": 5e-05
},
{
"epoch": 20,
"train_loss": 0.34317695209191873,
"val_loss": 0.8004909910796849,
"val_rmse": 0.8947016177568753,
"val_r2": 0.23108953692438994,
"lr": 5e-05
},
{
"epoch": 21,
"train_loss": 0.3332719436270763,
"val_loss": 0.7787629118531161,
"val_rmse": 0.8824754422784569,
"val_r2": 0.251960411536307,
"lr": 5e-05
},
{
"epoch": 22,
"train_loss": 0.3384761268649804,
"val_loss": 0.7856652471943075,
"val_rmse": 0.8863775950094339,
"val_r2": 0.24533038386710204,
"lr": 5e-05
},
{
"epoch": 23,
"train_loss": 0.310940025515745,
"val_loss": 0.790956350967305,
"val_rmse": 0.8893572619792587,
"val_r2": 0.24024802681949986,
"lr": 2.5e-05
},
{
"epoch": 24,
"train_loss": 0.30727086450616947,
"val_loss": 0.7933453949786374,
"val_rmse": 0.8906993813028119,
"val_r2": 0.2379532298009046,
"lr": 2.5e-05
},
{
"epoch": 25,
"train_loss": 0.30007334123885626,
"val_loss": 0.7868168299323205,
"val_rmse": 0.8870269603598935,
"val_r2": 0.24422422818004352,
"lr": 2.5e-05
},
{
"epoch": 26,
"train_loss": 0.3007251892450439,
"val_loss": 0.7781855312761179,
"val_rmse": 0.8821482466127635,
"val_r2": 0.25251501039626645,
"lr": 2.5e-05
}
]

3
models/pretrain_cv/fold_2/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:e12d57dff6ce45ec69eef25305dc614dade654f0ebb366192dca89e9ecdff157
size 28584172

90
models/pretrain_cv/fold_3/history.json
View File

@ -1,90 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.8049272903758325,
"val_loss": 0.7233524476227008,
"val_rmse": 0.8505012931595093,
"val_r2": 0.23420281907567997,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6724394139545847,
"val_loss": 0.7780079920040933,
"val_rmse": 0.8820476211055823,
"val_r2": 0.17634019497914522,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6226702311841568,
"val_loss": 0.7268287277535388,
"val_rmse": 0.8525425118433609,
"val_r2": 0.23052255349098238,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5807066261440482,
"val_loss": 0.7480401876725649,
"val_rmse": 0.8648931610246879,
"val_r2": 0.20806646702187126,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.5565325967568225,
"val_loss": 0.78764457169332,
"val_rmse": 0.8874934150154856,
"val_r2": 0.1661381872756985,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.5408692455237417,
"val_loss": 0.7449622110316628,
"val_rmse": 0.8631119349791895,
"val_r2": 0.21132504308155697,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5280002702356003,
"val_loss": 0.7270265375313006,
"val_rmse": 0.8526585107441463,
"val_r2": 0.2303131454929167,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.47815470421593387,
"val_loss": 0.7485054905477323,
"val_rmse": 0.8651621132668481,
"val_r2": 0.20757386186414217,
"lr": 5e-05
},
{
"epoch": 9,
"train_loss": 0.44686747415062394,
"val_loss": 0.7434620163942638,
"val_rmse": 0.8622424252651505,
"val_r2": 0.21291328462156855,
"lr": 5e-05
},
{
"epoch": 10,
"train_loss": 0.4486482603106318,
"val_loss": 0.7479210574375955,
"val_rmse": 0.8648242899336148,
"val_r2": 0.20819258469138113,
"lr": 5e-05
},
{
"epoch": 11,
"train_loss": 0.4326103016038595,
"val_loss": 0.7392987593224174,
"val_rmse": 0.8598248435346856,
"val_r2": 0.2173208126626488,
"lr": 5e-05
}
]

3
models/pretrain_cv/fold_3/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:2a2f62f357bf7a7fe389f9156fad8f4db37cd86ab2402ab99e0e4854b1cfcf08
size 28584172

90
models/pretrain_cv/fold_4/history.json
View File

@ -1,90 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.8368555589726097,
"val_loss": 0.7125106603565553,
"val_rmse": 0.8441034718158141,
"val_r2": 0.18080325582548262,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6790143709433706,
"val_loss": 0.7736326924319002,
"val_rmse": 0.8795639234921174,
"val_r2": 0.11052927201587359,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.6273591098032499,
"val_loss": 0.7311186972615996,
"val_rmse": 0.8550547893685072,
"val_r2": 0.15940900672576352,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5845285086255324,
"val_loss": 0.824912052230327,
"val_rmse": 0.9082466910090811,
"val_r2": 0.05157172462622084,
"lr": 0.0001
},
{
"epoch": 5,
"train_loss": 0.542804313333411,
"val_loss": 0.7959495350374681,
"val_rmse": 0.8921600398451272,
"val_r2": 0.08487087224465562,
"lr": 0.0001
},
{
"epoch": 6,
"train_loss": 0.532002612164146,
"val_loss": 0.7709247228206229,
"val_rmse": 0.8780231871088532,
"val_r2": 0.11364272306307566,
"lr": 0.0001
},
{
"epoch": 7,
"train_loss": 0.5044803537820515,
"val_loss": 0.7929024055826939,
"val_rmse": 0.8904506712121858,
"val_r2": 0.08837426708937035,
"lr": 0.0001
},
{
"epoch": 8,
"train_loss": 0.46425794064998627,
"val_loss": 0.8080452268227211,
"val_rmse": 0.8989133602081687,
"val_r2": 0.07096406033748759,
"lr": 5e-05
},
{
"epoch": 9,
"train_loss": 0.4466087131123794,
"val_loss": 0.7912134588730353,
"val_rmse": 0.8895018072231533,
"val_r2": 0.09031608819367143,
"lr": 5e-05
},
{
"epoch": 10,
"train_loss": 0.42657232159062436,
"val_loss": 0.8380918791833085,
"val_rmse": 0.9154735745461754,
"val_r2": 0.036418462892607084,
"lr": 5e-05
},
{
"epoch": 11,
"train_loss": 0.4110604504221364,
"val_loss": 0.817971889381322,
"val_rmse": 0.9044179837028969,
"val_r2": 0.05955105566092167,
"lr": 5e-05
}
]

3
models/pretrain_cv/fold_4/model.pt
View File

@ -1,3 +0,0 @@
version https://git-lfs.github.com/spec/v1
oid sha256:b19e74bdbf88f84cf60d3d6f44347aacceae87552394d525ad77a75ef6340aa4
size 28584172

63
models/pretrain_cv/test_results.json
View File

@ -1,63 +0,0 @@
{
"fold_results": [
{
"fold_idx": 0,
"n_samples": 2037,
"mse": 0.704966583529581,
"rmse": 0.8396228817329724,
"mae": 0.6275912649623819,
"r2": 0.18947693925460807,
"correlation": 0.4894546998045728
},
{
"fold_idx": 1,
"n_samples": 1658,
"mse": 0.9115043728317782,
"rmse": 0.9547273814193129,
"mae": 0.7232097773077567,
"r2": 0.21745691549383905,
"correlation": 0.48734383353129934
},
{
"fold_idx": 2,
"n_samples": 1615,
"mse": 0.8047081385461913,
"rmse": 0.8970552594718963,
"mae": 0.6672816107495062,
"r2": 0.18280256744724777,
"correlation": 0.506874931057286
},
{
"fold_idx": 3,
"n_samples": 1754,
"mse": 0.8592105232097863,
"rmse": 0.926936094458397,
"mae": 0.6835461141701688,
"r2": 0.1746865688538688,
"correlation": 0.4233578915460334
},
{
"fold_idx": 4,
"n_samples": 1520,
"mse": 0.6832138393192553,
"rmse": 0.8265675043934738,
"mae": 0.6324079235422495,
"r2": 0.2766966748218629,
"correlation": 0.5350317708563872
}
],
"summary_stats": {
"rmse_mean": 0.8889818242952104,
"rmse_std": 0.04931538867410365,
"r2_mean": 0.2082239331742853,
"r2_std": 0.03713816024862206
},
"overall": {
"n_samples": 8584,
"mse": 0.7912902048033758,
"rmse": 0.8895449425427452,
"mae": 0.6658137170204776,
"r2": 0.20870978896035208,
"correlation": 0.4812266887089009
}
}

4
models/pretrain_delivery.pt
View File

@ -1,3 +1,3 @@
version https://git-lfs.github.com/spec/v1
oid sha256:08fee22fae55ff10f6c4afccfb8ddd6916d946e27ed9609a1193070c13b24125
size 28617260
oid sha256:21439aa92b3b76ca3e0251fd293bffaf810c6f5c23e2b4e0065256c34282e6a8
size 28623340

288
models/pretrain_history.json
View File

@ -1,294 +1,142 @@
{
"train": [
{
"loss": 0.7867247516051271,
"n_samples": 6783
"loss": 0.7866107932915671,
"n_samples": 8236
},
{
"loss": 0.6515523084370274,
"n_samples": 6783
"loss": 0.6521620526367047,
"n_samples": 8236
},
{
"loss": 0.5990842743185651,
"n_samples": 6783
"loss": 0.6168191301961614,
"n_samples": 8236
},
{
"loss": 0.5633418128920326,
"n_samples": 6783
"loss": 0.5691385037288786,
"n_samples": 8236
},
{
"loss": 0.5453761521296815,
"n_samples": 6783
"loss": 0.5400582172443359,
"n_samples": 8236
},
{
"loss": 0.49953126002250825,
"n_samples": 6783
"loss": 0.5123824700387489,
"n_samples": 8236
},
{
"loss": 0.49147369265204843,
"n_samples": 6783
"loss": 0.49264508630535797,
"n_samples": 8236
},
{
"loss": 0.4659397622863399,
"n_samples": 6783
"loss": 0.47480573072023563,
"n_samples": 8236
},
{
"loss": 0.4653009635305819,
"n_samples": 6783
"loss": 0.45742412331962307,
"n_samples": 8236
},
{
"loss": 0.4380375076610923,
"n_samples": 6783
"loss": 0.4469649909392556,
"n_samples": 8236
},
{
"loss": 0.4258159104875806,
"n_samples": 6783
"loss": 0.4377749589474934,
"n_samples": 8236
},
{
"loss": 0.4144523660948226,
"n_samples": 6783
"loss": 0.4153644211261003,
"n_samples": 8236
},
{
"loss": 0.4008358244841981,
"n_samples": 6783
"loss": 0.41265021357911486,
"n_samples": 8236
},
{
"loss": 0.40240038808127093,
"n_samples": 6783
"loss": 0.37033110634107624,
"n_samples": 8236
},
{
"loss": 0.38176763174141226,
"n_samples": 6783
"loss": 0.36319094295638343,
"n_samples": 8236
},
{
"loss": 0.37277743237904,
"n_samples": 6783
"loss": 0.3601724639744826,
"n_samples": 8236
},
{
"loss": 0.3573742728176747,
"n_samples": 6783
},
{
"loss": 0.3491767022517619,
"n_samples": 6783
},
{
"loss": 0.3499675623860557,
"n_samples": 6783
},
{
"loss": 0.35079578643841286,
"n_samples": 6783
},
{
"loss": 0.3414057292594471,
"n_samples": 6783
},
{
"loss": 0.300529963052257,
"n_samples": 6783
},
{
"loss": 0.2961940902990875,
"n_samples": 6783
},
{
"loss": 0.2907693515383844,
"n_samples": 6783
},
{
"loss": 0.2809350616734551,
"n_samples": 6783
},
{
"loss": 0.28143580470326973,
"n_samples": 6783
},
{
"loss": 0.2664423378391215,
"n_samples": 6783
},
{
"loss": 0.2745858784487654,
"n_samples": 6783
},
{
"loss": 0.26682337215652197,
"n_samples": 6783
},
{
"loss": 0.2681302405486289,
"n_samples": 6783
},
{
"loss": 0.26258669999889017,
"n_samples": 6783
},
{
"loss": 0.2608744821883436,
"n_samples": 6783
},
{
"loss": 0.239722755447208,
"n_samples": 6783
},
{
"loss": 0.24175641130912484,
"n_samples": 6783
},
{
"loss": 0.23785491213674798,
"n_samples": 6783
},
{
"loss": 0.23117999019839675,
"n_samples": 6783
"loss": 0.344626752713052,
"n_samples": 8236
}
],
"val": [
{
"loss": 0.7379055186813953,
"n_samples": 2907
"loss": 0.7430127724656704,
"n_samples": 1454
},
{
"loss": 0.7269540305477178,
"n_samples": 2907
"loss": 0.6653193087000631,
"n_samples": 1454
},
{
"loss": 0.6927794775152518,
"n_samples": 2907
"loss": 0.643206344510043,
"n_samples": 1454
},
{
"loss": 0.6652627856533758,
"n_samples": 2907
"loss": 0.6357355561348235,
"n_samples": 1454
},
{
"loss": 0.6721626692594103,
"n_samples": 2907
"loss": 0.6296598366070975,
"n_samples": 1454
},
{
"loss": 0.6660812889787394,
"n_samples": 2907
"loss": 0.6274867772728082,
"n_samples": 1454
},
{
"loss": 0.6329412659009298,
"n_samples": 2907
"loss": 0.5899985940125162,
"n_samples": 1454
},
{
"loss": 0.6395346636332554,
"n_samples": 2907
"loss": 0.6106109730643124,
"n_samples": 1454
},
{
"loss": 0.6228037932749914,
"n_samples": 2907
"loss": 0.6522176828148276,
"n_samples": 1454
},
{
"loss": 0.627341245329581,
"n_samples": 2907
"loss": 0.6298340477838477,
"n_samples": 1454
},
{
"loss": 0.6399482499704272,
"n_samples": 2907
"loss": 0.6169055035386486,
"n_samples": 1454
},
{
"loss": 0.6136556721283145,
"n_samples": 2907
"loss": 0.6135227742516519,
"n_samples": 1454
},
{
"loss": 0.6253821217484764,
"n_samples": 2907
"loss": 0.5915408500123057,
"n_samples": 1454
},
{
"loss": 0.6535878175511408,
"n_samples": 2907
"loss": 0.6030011913307431,
"n_samples": 1454
},
{
"loss": 0.6123772015635566,
"n_samples": 2907
"loss": 0.6057224867268475,
"n_samples": 1454
},
{
"loss": 0.648116178003258,
"n_samples": 2907
"loss": 0.6045601750830345,
"n_samples": 1454
},
{
"loss": 0.6141229696318092,
"n_samples": 2907
},
{
"loss": 0.6307853255273552,
"n_samples": 2907
},
{
"loss": 0.6422428293329848,
"n_samples": 2907
},
{
"loss": 0.6552245357949421,
"n_samples": 2907
},
{
"loss": 0.6614342853503823,
"n_samples": 2907
},
{
"loss": 0.6153881246378465,
"n_samples": 2907
},
{
"loss": 0.6298057977526632,
"n_samples": 2907
},
{
"loss": 0.6117005377321011,
"n_samples": 2907
},
{
"loss": 0.618167482426702,
"n_samples": 2907
},
{
"loss": 0.6103124622220963,
"n_samples": 2907
},
{
"loss": 0.6203263100988888,
"n_samples": 2907
},
{
"loss": 0.617202088939065,
"n_samples": 2907
},
{
"loss": 0.6263537556599373,
"n_samples": 2907
},
{
"loss": 0.6461186489679168,
"n_samples": 2907
},
{
"loss": 0.6289772454163526,
"n_samples": 2907
},
{
"loss": 0.6347806630652919,
"n_samples": 2907
},
{
"loss": 0.6358688624302136,
"n_samples": 2907
},
{
"loss": 0.646931814478975,
"n_samples": 2907
},
{
"loss": 0.6245040218978556,
"n_samples": 2907
},
{
"loss": 0.6267098000482632,
"n_samples": 2907
"loss": 0.5934982676945494,
"n_samples": 1454
}
]
}

Some files were not shown because too many files have changed in this diff Show More