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Makefile
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@ -122,26 +122,6 @@ train: requirements
$(DEVICE_FLAG) $(MPNN_FLAG) $(SEED_FLAG) $(INIT_PRETRAIN_FLAG) \
$(N_TRIALS_FLAG) $(EPOCHS_PER_TRIAL_FLAG) $(MIN_STRATUM_FLAG) $(OUTPUT_DIR_FLAG) $(USE_SWA_FLAG)
#################################################################################
# INTERPRETABILITY #
#################################################################################
# 参数：
# TASK 目标任务 (delivery, size, pdi, ee, biodist, toxic; 默认: delivery)
# METHOD 方法 (ig, ablation, attention, all; 默认: all)
# DATA 数据路径 (默认: data/processed/train.parquet)
# MODEL 模型路径 (默认: models/model.pt)
TASK_FLAG = $(if $(TASK),--task $(TASK),)
METHOD_FLAG = $(if $(METHOD),--method $(METHOD),)
DATA_FLAG = $(if $(DATA),--data-path $(DATA),)
MODEL_FLAG = $(if $(MODEL),--model-path $(MODEL),)
## Compute token-level feature importance
.PHONY: feature_importance
feature_importance: requirements
$(PYTHON_INTERPRETER) -m lnp_ml.interpretability.token_importance \
$(TASK_FLAG) $(METHOD_FLAG) $(DATA_FLAG) $(MODEL_FLAG) $(DEVICE_FLAG)
#################################################################################
# SERVING & DEPLOYMENT #
#################################################################################

840
data/interim/internal.csv
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@ -1,421 +1,421 @@
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CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4135253017332525,0.0,0.00151329913495755,0.0471551068594211,0.0476760649180962,0.00182335320536251,0.00763287581452213,0.89419930006764,0.35502103370942,0.35502103370942,-0.5325147239258616
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.509649984130679,0.0,0.00235961766437825,0.513627015742916,0.0879412499947796,0.00175822838354556,0.00311254749811917,0.391201340716262,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.496359280129911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC,DSPC,0,0,1,0,14.13296737,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.170425586627436,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.445353484534206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,15.1299087,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.166510173022286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.673109168996284,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.72728505,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.7572902340489245,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.000230328920605394,0.0259372790881254,0.0734981485145439,0.000576894596302152,0.000867946038939987,0.898889402841483,0.486446282346577,0.486446282346577,-0.34493999468492637
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,18.33700102,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.00183814880222334,0.508470854676458,0.479298868566087,0.00664368457868438,0.00374844337654761,0.0,0.0806697533656258,0.0806697533656258,-0.5836902104683951
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,14.7050121,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.00446051681777838,0.0286140231457339,0.01484311836534,0.00629790100652696,0.01599114503205,0.929793295632571,0.0275210452544693,0.0275210452544693,-0.9999342060867568
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.7050121,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.0104002218216073,0.139229779861971,0.807246421461676,0.041233674188,0.00188990266674509,0.0,0.0040656278842911,0.0040656278842911,-0.7881076899433005
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.00711911642710361,0.153280595121264,0.136743424441396,0.0628412485834964,0.0734141937722642,0.566601421654476,0.0027486514420013,0.0027486514420013,-1.0352902363032352
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.106975953776871,0.247623902989694,0.292657465739291,0.229416263063982,0.123326414430162,0.0,0.001042320755636,0.001042320755636,-0.7961753601769197
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.789157022101107,0.0,0.0386975655052687,0.153034034478582,0.0799184464451532,0.0414429326981307,0.0607210626185958,0.626185958254269,0.0073827728841294,0.0073827728841294,-1.0286762554754216
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,1,0,0,0,0.0,4.639571612705423,0.0,0.135531713474282,0.541180183023036,0.178510571158094,0.0949195329757021,0.0498579993688861,0.0,0.004009461265808,0.004009461265808,-0.7882575701032632
O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,15.91058453,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.639571612705423,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.000231298468169262,0.195828728849491,0.0126185833117857,0.000504922171493209,0.00109315352063243,0.789723313678428,1.0,1.0,0.38802190219888055
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CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0963955724315343,0.000259669027359828,0.0209585518067849,0.0324510369422159,0.00191021824445882,0.00526970020363582,0.84275525134401,0.95415067884307,0.95415067884307,0.32258414125816925
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0,0.00301852406237983,0.561715155652109,0.427466534539213,0.00675382930885143,0.00104595643744612,0.0,0.469108231863161,0.469108231863161,0.4528546780295592
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O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0159262664008309,0.00726471746994425,0.0644691443511897,0.0154248397225439,0.00666778094817397,0.00618426236554005,0.884062988741777,0.163983867672707,0.163983867672707,-0.8051696746745034
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O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.285378059618076,0.00952025723585679,0.00424787112198889,0.0270494802958792,0.00951147065788185,0.00569809581675416,0.00864159943836194,0.935331225433277,0.22281247574214,0.22281247574214,-0.7212074197450102
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.285378059618076,0.0,0.00577401787332259,0.781123329740865,0.202386288853494,0.00852464019685452,0.00219172333546338,0.0,0.23688698835255,0.23688698835255,-0.16682580237138014
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0307690543253117,0.000803846893528031,0.00327375890943859,0.00440309874760962,0.00131506681420977,0.00341198428561488,0.956023190024287,1.14370500641117,1.14370500641117,0.5931227328814345
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0,0.0103006057269574,0.229208194092422,0.735779643429865,0.0182228400970524,0.00648871665370264,0.0,0.146101132843469,0.146101132843469,-0.40908711190961344
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.573885895948325,0.00305704097815131,0.00100491779320209,0.0165773259574103,0.0117710271412967,0.00208697129856503,0.00287252217431477,0.96263019465706,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.573885895948325,0.0,0.00330040832612047,0.545398801975274,0.446192251044312,0.00323782528214899,0.00187071337214386,0.0,1.0,1.0,1.8695349995476385
O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.79756457,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.789042318607025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.40770989,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.168208681201016,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.93089479,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.697749367281184,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.38737682,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.2112383136936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.61200662,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.27999390910873,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.611152257665639,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.1422481808981475,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.515354881665727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.57532934397707,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.451896454476337,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9250774057346085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.829912458665998,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421728001525434,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.775756486563625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.862341963516347,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.55042057,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,5.550631295162026,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.34229222,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.47597224751641,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.30473405,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.563722996073918,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O,DSPC,0,0,1,0,16.11614863,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.275554390163364,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O,DSPC,0,0,1,0,16.80938411,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.35709336812867,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.32727581,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.473579765600494,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,17.03239796,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.5612182984589085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.71577453,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.695924549256556,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.72351388,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.857484114602081,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.6246954,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.483228515182849,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O,DSPC,0,0,1,0,16.38850868,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.426521874560432,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O,DSPC,0,0,1,0,17.04402965,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.412919498116252,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.53558149,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.69866052907543,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.95535314,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.9459189793765646,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.450269224770129,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.46731585,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.659658371272161,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.8769168,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.139321635057579,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.04309994,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.283448621312786,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O,DSPC,0,0,1,0,17.76093253,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1455128487965,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,18.07661492,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.3551691805039985,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.632923618509176,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-],DSPC,0,0,1,0,12.69438691,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TEA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.762173934797756,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0111914004572023,0.00227125491616379,0.00877931935589419,0.0082437061808303,0.00401873844514775,0.00849693826019724,0.956998642384564,0.596141429580998,0.596141429580998,-0.18837922911736
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0,0.00531733106486159,0.69156525750989,0.28508003495893,0.0160312488066627,0.00200612765965623,0.0,0.176602424488684,0.176602424488684,-0.3276946657499996
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O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.8896653,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.363226005210164,0.0302618004269707,0.0170318389360463,0.0852511261606349,0.0321310738618372,0.020553836096385,0.0249767617646758,0.78979356275345,0.103578477209434,0.103578477209434,-0.8913823687978608
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CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.602904588,25.0,40.0,30.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.2162671661789055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.22342652,38.46153846,21.97802198,38.46153846,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.634728988229636,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.21412129,40.0,34.28571429,22.85714286,2.857142857,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.378896741664954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.29890072,34.65346535,39.6039604,24.75247525,0.99009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.661550519424199,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.62419529,41.86046512,37.20930233,18.60465116,2.325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.552612935249416,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,5.021245473208271,0.0189024787568605,0.00542838949966448,0.0161874266221436,0.00564673685028802,0.0063903753402389,0.0111802988958026,0.936264294035002,0.0913658402077254,0.0913658402077254,-0.908812673116613
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.59373115,37.83783784,37.83783784,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.484470400750307,0.220192249542946,0.000764987158036526,0.00117389921248248,0.000355328494502401,0.000727082388944626,0.00146163086877099,0.775324822334317,0.909323670538887,0.909323670538887,0.25860546111465654
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.02523135,35.8974359,41.02564103,20.51282051,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.474947598938117,0.0634606467339624,0.00208550415241484,0.000693953783467295,0.000703971489002912,0.00107462659382075,0.00306678394465369,0.928914513302678,0.68813569412733,0.68813569412733,-0.057081784806354334
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.414493824811383,0.0115671522937999,0.000329262998462127,0.000782715410474643,0.000454168201139608,0.00050928396392566,0.0365052454816706,0.949852171650527,1.45919493888772,1.45919493888772,1.0434010414727322
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.50825332,52.83018868,26.41509434,18.86792453,1.886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573163389853005,0.0289504727873473,0.000587630380490671,0.00098172979734669,0.000247631664832521,0.000530890620697785,0.00148666967519347,0.967214975074092,1.18732779204068,1.18732779204068,0.6553827041429786
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.02959744,50.90909091,29.09090909,18.18181818,1.818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.424367475163407,0.01918176556647,0.0010650954164724,0.0022206234626453,0.00126505200881015,0.0010329415925789,0.00258134917445057,0.972653172778573,0.519739549496667,0.519739549496667,-0.29742267487018065
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.0526464,43.24324324,32.43243243,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.646312129319266,0.0173760673957131,0.000550323482827711,0.00231355504088989,0.000799250291024724,0.00171157517792979,0.00187915335599706,0.975370075255618,0.641975082983608,0.641975082983608,-0.12296382974571453
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87880561,39.02439024,39.02439024,19.51219512,2.43902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.62790967295758,0.031425165165133,0.00121897501467252,0.00336392108926765,0.00273184674446895,0.00365496097119473,0.00253008289994281,0.95507504811532,0.292484943880311,0.292484943880311,-0.6217684269937327
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.72896002,41.02564103,30.76923077,25.64102564,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.6141299273595635,0.00243290161785256,0.00374029360494432,0.00771109158226845,0.00256075951190699,0.0024473081411263,0.00398520450059787,0.977122441041304,0.29000081469118,0.29000081469118,-0.6253138633910964
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2936051730729785,0.0291199872991734,0.000702410023626044,0.0253755412996204,0.0176881988849176,0.000962484515645204,0.00126799370807735,0.92488338426894,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.596835549198033,0.0642873127295256,0.000194616801396495,0.00548703707264694,0.0163820187916684,0.000849254927099769,0.000518055392084143,0.912281704285579,0.772854925639995,0.772854925639995,0.06383247693007311
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.26769266,37.83783784,37.83783784,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.284827171296749,0.000820324065776298,6.77505055763446e-05,0.00130838737685328,0.00203458073148474,0.00044026025400656,0.00179231955954145,0.993536377506761,0.647354606156059,0.647354606156059,-0.11528598539707118
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.69845587,35.8974359,41.02564103,20.51282051,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.355939299910563,0.000606683031689403,0.000350488437662207,0.00200552330636915,0.00341592792036262,0.00135658595795651,0.00484812686613966,0.98741666447982,0.429472560198128,0.429472560198128,-0.42625489130230415
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.73864775,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.210051369934071,0.0506054803736383,0.000934742670841204,0.00195746112246746,0.00131704918881155,0.00229254534633995,0.00362188526923176,0.93927083602867,0.295296757118666,0.295296757118666,-0.6177553084162161
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.22254695,52.83018868,26.41509434,18.86792453,1.886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.19614876167715,0.000394517913167851,0.000925918583325644,0.00219111536287718,0.00192843383777798,0.00141208216065332,0.00279803133939282,0.990349900802805,0.423957111788814,0.423957111788814,-0.43412673292138043
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.73562869,50.90909091,29.09090909,18.18181818,1.818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.324000197151533,0.0149763371723649,9.09516394922477e-05,0.00865819492777344,0.00337158611087041,0.000870833891384162,0.00234291805381448,0.9696891782043,0.799987755503576,0.799987755503576,0.10255740435442702
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.73441264,43.24324324,32.43243243,21.62162162,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.638604962074329,0.00412763242238728,0.000587351434637121,0.00125519721482213,0.00156835329887146,0.00151910105091065,0.00332452673735467,0.987617837841017,0.519710678404319,0.519710678404319,-0.29746388070685387
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.55362203,39.02439024,39.02439024,19.51219512,2.43902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.465448242812954,0.001908149535057,0.00051106883667359,0.00195557181028906,0.00222543526142979,0.00102554934782431,0.0036709617373884,0.988703263471338,0.559906246507883,0.559906246507883,-0.24009535462913364
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.4082575,41.02564103,30.76923077,25.64102564,2.564102564,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.439351701293151,0.0164941051995163,0.00133624924425635,0.0136411729141475,0.0068725438331318,0.00281561744256348,0.00565863059250302,0.953181680773882,0.404416041627467,0.404416041627467,-0.4620164343493942
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.348211286179151,0.25310386523031,0.000588156076259717,0.140706646889545,0.17621759673582,0.00218337900345845,0.000839731767209391,0.426360624297398,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.574298522321004,0.0173152888243317,0.00170643426094864,0.0181271736370668,0.0103847448319841,0.00234708518590686,0.00464250497463967,0.945476768285122,0.880302275630684,0.880302275630684,0.21718510735044552
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.54771521,32.96703297,21.97802198,43.95604396,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5300155123873305,0.0022188818222417,0.00151967168045253,0.0265741083102934,0.00935341146520975,0.00161955884356527,0.00594450434134348,0.952769863536894,0.693395601815244,0.693395601815244,-0.0495746598769834
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.03951812,41.32231405,16.52892562,41.32231405,0.826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.640537329825382,0.0191565810814788,0.00120917820488213,0.00564887782228727,0.00368324602436162,0.00270413188019715,0.00625226385441887,0.961345721132374,0.702078866162311,0.702078866162311,-0.037181600128431615
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,10.8033785,27.02702703,32.43243243,37.83783784,2.702702703,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.2431955089544555,0.0191175904912105,0.0046774627841674,0.0253721583259607,0.0153479247605493,0.0105242912643767,0.0240873946993884,0.900873177674347,0.168910555827937,0.168910555827937,-0.7981381323616322
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,9.298704135,25.0,40.0,30.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.822697998516666,0.00783638212803346,0.00315432464612104,0.0156004284210389,0.0122536904537434,0.00649575798551451,0.014293561001533,0.940365855364016,0.26946434750834,0.26946434750834,-0.6546242303969191
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.90666525,38.46153846,21.97802198,38.46153846,1.098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.291292751611072,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.89035919,40.0,34.28571429,22.85714286,2.857142857,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.388753955423308,0.0457836478243602,0.00256820195313693,0.0933595380902435,0.040121791020458,0.00303459231576053,0.00719748271402532,0.807934746082015,0.638042293066864,0.638042293066864,-0.12857684559650717
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.97231927,34.65346535,39.6039604,24.75247525,0.99009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.500031867864786,0.00367784574047392,0.00111977791364668,0.0109807451773001,0.00533981749985873,0.0035253353907892,0.00945759694134628,0.965898881336585,0.664597706735618,0.664597706735618,-0.09067602683869287
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.30278396,41.86046512,37.20930233,18.60465116,2.325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.578518154990665,0.00602415700375336,0.00352191807012307,0.0129438874596237,0.0112365957475355,0.00705054455561779,0.0163551166761144,0.942867780487232,0.387412476367661,0.387412476367661,-0.486284519689253
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DOPE,1,0,0,0,14.78083639,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.373742415086184,0.00132025329631253,0.000860633620224201,0.00503931327076771,0.0029913613071963,0.00270028184029275,0.0088532339643477,0.978234922700859,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.434619084793052,0.00770185399584477,0.00244833711322221,0.0462111239750686,0.0198642411939162,0.00381226904350308,0.00922041774380283,0.910741756934642,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,11.7812451,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.485936098064393,0.00448668985970796,0.00155299888410839,0.00808200908228358,0.00771278024096098,0.00385266053622471,0.00536687174407294,0.968945989652641,1.22295554827804,1.22295554827804,0.7062318887477964
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,54.90196078,23.52941176,19.60784314,1.960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.73444252169223,0.00221922165343577,0.00134658478491355,0.00928071520245763,0.0103471897935628,0.00308928870366618,0.00305991935175966,0.970657080510204,2.4848301850992,2.4848301850992,2.507223675274371
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,50.0,10.0,38.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.7140245909001735,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.85564,30.9,36.3,25.9,6.9,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.002960000420248,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.10629825,33.7,32.2,28.8,5.4,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,3.9917579734469992,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.076607527,21.5,44.3,27.4,6.7,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.150252194160396,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.262126773,28.5,36.9,23.3,11.4,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,3.938470175442994,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.14390228,47.0,40.4,5.7,6.8,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.139158578011893,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.465333240800292,0.0929588198875335,0.00109661539851913,0.0103406974639253,0.00262333547972377,0.00257373980843396,0.00319533888859958,0.887211453073265,2.49616154919077,2.49616154919077,2.5233961959539766
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,41.0,39.5,16.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.25063580654847,0.00217929592656579,0.00233573351378476,0.00718449647353577,0.00718369422949875,0.00471157922942054,0.00408542775852615,0.972319772868668,1.71461830076508,1.71461830076508,1.4079502315467747
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.40653622,31.3333,31.3333,31.3333,6.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.188896879163323,0.0142737392382439,0.00348189340868737,0.00880858320276677,0.0038525568856599,0.00593274588142816,0.00610316587084082,0.957547315512373,0.645718762121967,0.645718762121967,-0.11762071943757772
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,50.0,23.5,23.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.343935283551159,0.0065593281978378,0.00138907609400551,0.00613919753007927,0.00613411120238244,0.00366825953495706,0.00406194129869205,0.972048086142046,1.35219591573978,1.35219591573978,0.890688278863242
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.200348974,22.0,22.0,50.0,6.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.057161771094385,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.72417162,27.0,27.0,41.0,5.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.102973888920155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.092439729,16.0,39.5,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.127940511650616,0.0097349353786325,0.00823434520879355,0.0380775286515883,0.0189007253206434,0.0281939358827934,0.0273826912679074,0.869475838289641,0.161929321885153,0.161929321885153,-0.8081019945583146
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,39.5,16.0,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.116269119637892,0.00176070173692806,0.00134882241229812,0.00721447825021801,0.00277771416530431,0.00258248336542972,0.00338400053115958,0.980931799538662,0.834918279031508,0.834918279031508,0.15241147395626697
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.312676556539088,0.0122849683487715,0.00187692747865846,0.313004652084084,0.0267625511357853,0.00478000951875277,0.00400214034383056,0.637288751090117,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5612182984589085,0.00230427148121394,0.00151653786120671,0.00981883965091339,0.0195498469521307,0.00278714514326426,0.00256552165624032,0.961457837255031,3.54213716664653,3.54213716664653,4.0162493217529285
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,41.0,39.5,16.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.2756934238792645,0.00339636246099529,0.00439836397767252,0.00922438120812044,0.0070906355917358,0.00777777401057153,0.0070228258793507,0.961089656871554,1.60048193764837,1.60048193764837,1.2450508067393784
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,50.0,23.5,23.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.300138475201197,0.0251900613139205,0.0263858529561065,0.0690244086529141,0.0290319859464883,0.0512059292322219,0.0395084822769767,0.759653279621372,0.244442812501583,0.244442812501583,-0.6903358436733202
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,39.5,16.0,41.0,3.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.035478809355064,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.314416735011824,0.00832740543716945,0.00279899792781369,0.0133506530995165,0.00590470004845411,0.00800781451355169,0.00611088774111073,0.955499541232384,1.4036171732161,1.4036171732161,0.9640785029516001
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.46964291,32.3,32.3,32.3,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.122932019074013,0.00935369123549862,0.00681432683334856,0.0266295187790274,0.0091342786879667,0.0148394527045059,0.0109795829907811,0.922249148768872,0.807897092094877,0.807897092094877,0.11384588723707807
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.214347354616797,0.00175971204953205,0.0023945553766021,0.00864096914216858,0.00287247113967731,0.00354165273920712,0.00438932700137801,0.976401312551435,2.1807873939408,2.1807873939408,2.073283128685432
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.297557478047431,0.0163588203416613,0.0050349858804786,0.141665503002976,0.0268932928836599,0.0108166459136593,0.00842178986187252,0.790808962115693,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.623991940228679,0.0114998638575461,0.00130788860611426,0.00505223783079306,0.0046933168158669,0.00183202266239377,0.00287251942980201,0.972742150797484,1.19732008331576,1.19732008331576,0.6696440530835793
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.47398367,41.5,40.5,16.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.261975403606051,0.0120973279883405,0.00779128029381303,0.0260350268299895,0.0160802201335602,0.0156019499205845,0.0170739234476819,0.90532027138603,0.213285375768679,0.213285375768679,-0.7348048313269125
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.72570651,40.5,16.0,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.168678699274804,0.00644850088058007,0.00798921970887525,0.0221223520376599,0.0111631004951633,0.0106463671035197,0.00996963598739929,0.931660823786802,0.29077874869216,0.29077874869216,-0.6242035686713655
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.63764671,41.5,40.5,16.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.40562108352751,0.0088141667427258,0.00585903666298478,0.0157870816204507,0.010986042994209,0.00978368783097364,0.0102623946891479,0.938507589459508,0.370029347989408,0.370029347989408,-0.5110943308383519
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.402441819416474,0.154933534385178,0.00229861102597737,0.00525615721273492,0.00408539799683711,0.0022876287732977,0.00287249757879639,0.828266173027179,1.34933481107146,1.34933481107146,0.88660480982624
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.91076362,42.0,40.5,16.5,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.607168188650764,0.0408588610755303,0.0177373482989948,0.0425327283385076,0.0277718677406049,0.0276871974121274,0.0218927074965806,0.821519289637654,0.158736230637426,0.158736230637426,-0.8126592864976097
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.427716760590997,0.00307921600642319,0.00224989559352084,0.00599370029233814,0.00443157985269048,0.00263031532778781,0.00293093049696406,0.978684362430275,1.27822314397057,1.27822314397057,0.785111741784596
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.444179499895966,0.0412236553892641,0.00390663231476925,0.121517080143859,0.0188177267921366,0.00482332620655526,0.0073631886059774,0.802348390547439,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573473099244836,0.00689869445402741,0.00600089779665737,0.0191135089301672,0.00620664286397134,0.00981653359048003,0.0097967903769499,0.942166931987747,0.749333285576466,0.749333285576466,0.030261566378477555
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.88644869,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.688591794127164,0.00886147101476089,0.00436553876298869,0.0150948084008648,0.00476112441477112,0.00826588994437132,0.00836456609804533,0.950286601364198,0.883781845590108,0.883781845590108,0.22215127176544153
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.877221176,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.829113417472866,0.00517423746484337,0.00420818785762778,0.0136338012801862,0.00389526355348657,0.0081026937251479,0.00825574629036951,0.956730069828339,1.02766134878372,1.02766134878372,0.4275011503825392
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4595662121293,0.025369932029363,0.00629969301959379,0.0185849502075566,0.00668329267445478,0.00984673129800659,0.00995848867776924,0.923256912093256,0.773367707896157,0.773367707896157,0.06456433777003012
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.306031912,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.528073135603124,0.00974026247143072,0.00459547921939943,0.0155882894773368,0.00424301614179951,0.00735125258984654,0.00918675243548622,0.949294947664701,0.925634770529548,0.925634770529548,0.28188523570969626
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,6.950074466,41.0,40.0,16.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.730921391293651,0.0307398296858454,0.00502448817507942,0.0144391987292623,0.00475975114719379,0.00732990645958348,0.00864531856689022,0.929061507236145,0.282355212986546,0.282355212986546,-0.6362259345836732
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3578620076745835,0.0575651939642587,0.00224327504140443,0.293214190330324,0.103801109257072,0.00316596887134689,0.00243404296405076,0.537576219571543,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1515122352784415,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.2656332579940335,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.431173877940127,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.436396441739405,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.5666372362713075,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.765586907393996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.149936935645806,0.0412282002133458,0.00282906106065428,0.0100452919302821,0.00294646346634102,0.0035555046437446,0.00510039590268196,0.93429508278295,2.31132936702855,2.31132936702855,2.259597216050143
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.244200317766478,0.0307672106546614,0.0492440442693678,0.143087600825361,0.0409904333145751,0.0410729694241231,0.0628737572688051,0.631963984243106,0.159668526820479,0.159668526820479,-0.8113286806519148
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,40.0,16.0,41.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.430459592195471,0.0144382835185698,0.030629687100469,0.0904231657039977,0.0327120644783899,0.0374915496460484,0.0408664371206098,0.753438812431916,0.342029093157046,0.342029093157046,-0.551057277633741
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.560277417097355,0.064087583051715,0.00731756531038673,0.0186036957891068,0.0053871458118381,0.00655845861152129,0.0086069303650773,0.889438621060355,2.14638048731397,2.14638048731397,2.024176383509215
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.667205576907544,0.00310349569550498,0.00416831577034203,0.0115025538737423,0.00349250282837259,0.00500126547712412,0.00690260249517487,0.965829263859739,3.35844880423818,3.35844880423818,3.754082841561727
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,40.5,16.5,41.5,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.713127327493184,0.00089376253365906,0.00183788568066981,0.0054363636464257,0.00195410248071216,0.00225811087193407,0.00383533887250888,0.98378443591409,3.24722414573894,3.24722414573894,3.595339103815341
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.359653205696989,0.0828383439279835,0.00565653685524585,0.157248489872984,0.00928479521934879,0.00688752099561758,0.00841921269728692,0.729665100431533,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.634728988229636,0.00818072805535472,0.00273349879854757,0.0119346096951512,0.0075308964437597,0.00591367796700706,0.00578329104170321,0.957923297998477,0.213428398303373,0.213428398303373,-0.7346007045438266
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.15051107,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.7140245909001735,0.0160361616147136,0.00185083446366488,0.00730973501824061,0.00349956550575257,0.00416153151105757,0.00426975100661699,0.962872420879954,0.319359456002154,0.319359456002154,-0.5834121797200126
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.327596879,49.0,25.0,24.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.822697998516666,0.0208671125611406,0.0200298903914976,0.0765668274895919,0.0297655881927753,0.0442427715485906,0.0417155046265625,0.766812305189841,0.0431568482237034,0.0431568482237034,-0.9776182391106099
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.548282323781043,0.235642631118293,0.00357683071882224,0.268183756367962,0.0537803810677977,0.0056567696761597,0.00550191880428196,0.427657712246684,1.0,1.0,0.38802190219888055
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.41834022,50.0,7.5,41.5,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.892602227184663,0.0004,0.0007,0.8627,0.1335,0.0019,0.0008,0.0,0.33,0.33,0.08164550420240263
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.34376213,50.0,29.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.935911747900319,0.0015,0.0017,0.585,0.3856,0.0215,0.0046,0.0,0.09,0.09,-0.5587925239809655
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.47881241,45.5,7.5,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.657762636107262,0.0008,0.0009,0.9399,0.0565,0.0012,0.0006,0.0,0.26,0.26,-0.10514892068441307
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.58994389,50.0,17.75,30.25,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6520537718869415,0.0009,0.0008,0.8853,0.11,0.0021,0.0009,0.0,0.31,0.31,0.028275668520455245
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.356515817,38.0,30.0,30.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.522874943261261,0.0008,0.0012,0.7508,0.2416,0.0048,0.0008,0.0,0.12,0.12,-0.4787377704580445
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.211083767,38.0,16.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.802380355275797,0.0003,0.0007,0.8979,0.0985,0.0022,0.0005,0.0,0.45,0.45,0.40186451829408665
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.891852481,38.0,23.0,38.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.721173861744397,0.0003,0.0009,0.9061,0.0898,0.0024,0.0005,0.0,0.3,0.3,0.0015907506794815506
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.59856338,45.96,24.83,26.71,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.599152113662528,0.0006,0.0011,0.8386,0.1563,0.0028,0.0007,0.0,0.36,0.36,0.16170025772532357
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.516252746,44.58,19.33,33.08,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.539030383483546,0.0011,0.0009,0.9163,0.0784,0.0025,0.0008,0.0,0.24,0.24,-0.15851875636636045
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.79855736,50.0,7.5,39.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.602165676967792,0.0007,0.0007,0.9622,0.0349,0.001,0.0005,0.0,0.91,0.91,1.6293707389788754
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OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.924427289,44.71,13.58,39.21,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.543294782270004,0.0006,0.0008,0.9464,0.0496,0.0015,0.0011,0.0,0.56,0.56,0.6953986145447971
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.213203287,41.46,24.83,32.21,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.600157644164547,0.0006,0.0011,0.9277,0.0684,0.0014,0.0008,0.0,0.44,0.44,0.37517960045311294
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.766920469,38.0,14.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.380775852772229,0.0005,0.001,0.9807,0.0157,0.0015,0.0006,0.0,0.46,0.46,0.42854943613506036
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.9150442,50.0,27.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.490881039585964,0.0013,0.001,0.7257,0.2649,0.0061,0.0009,0.0,0.13,0.13,-0.4520528526170708
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.33144164,47.24,11.19,38.87,2.71,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.62790967295758,0.0073,0.0639,0.7768,0.1461,0.0042,0.0016,0.0,1.3,1.3,2.670082534776849
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.92222847,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.8543712716215905,0.001,0.001,0.8647,0.1302,0.0025,0.0007,0.0,0.25,0.25,-0.13183383852538677
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.314817884980432,0.0009,0.0007,0.9116,0.0844,0.0018,0.0006,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.42041204,49.0,7.5,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.534747721691545,0.0013,0.0021,0.5194,0.4632,0.0111,0.0029,0.0,0.5,0.5,0.535289107498955
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,15.70987342,34.25,18.75,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.19116874685764,0.0011,0.0011,0.7685,0.2222,0.0053,0.0018,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,11.2192693,22.0,30.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0028,0.0014,0.4022,0.5806,0.0101,0.003,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.76101632,49.0,28.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.154184562578117,0.001,0.0012,0.5862,0.3912,0.0188,0.0017,0.0,0.16,0.16,-0.37199809909414977
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.31421044,44.61,24.89,27.94,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.155753190350744,0.0041,0.0015,0.5886,0.3825,0.0211,0.0022,0.0,0.13,0.13,-0.4520528526170708
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.60470229,32.11,24.89,40.44,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.104294893075268,0.0017,0.0016,0.5892,0.3913,0.0129,0.0033,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.00750041,49.0,18.75,31.25,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0111,0.0048,0.1796,0.7293,0.0671,0.0082,0.0,0.14,0.14,-0.4253679347760971
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O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.21646499,45.61,13.64,38.19,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.365643155423357,0.0042,0.0015,0.3443,0.6172,0.0298,0.003,0.0,0.2,0.2,-0.2652584277302551
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27353562,44.5,7.5,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.436751534363128,0.0067,0.0013,0.5909,0.385,0.0142,0.0019,0.0,0.22,0.22,-0.21188859204830776
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27759176,49.0,30.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0122,0.0028,0.2395,0.6818,0.0594,0.0044,0.0,0.08,0.08,-0.5854774418219391
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.75114553,34.5,30.0,32.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.2484952420493585,0.0029,0.0024,0.3338,0.6429,0.0151,0.0029,0.0,0.07,0.07,-0.6121623596629128
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.61008,39.36,24.89,34.19,1.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.384523514872469,0.0141,0.0106,0.3243,0.5845,0.0592,0.0073,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,12.46688772,24.0,30.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.796616650559046,0.0064,0.0026,0.3777,0.6006,0.0093,0.0034,0.0,0.1,0.1,-0.5321076061399918
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,46.5,7.5,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0024,0.0028,0.4642,0.5174,0.0093,0.0039,0.0,0.81,0.81,1.362521560569139
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.04448224,37.36,29.94,31.71,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.370712874773608,0.033,0.008,0.1094,0.8115,0.0325,0.0056,0.0,0.11,0.11,-0.5054226882990182
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.623010104116422,0.0087,0.0033,0.2348,0.7393,0.011,0.003,0.0,0.36,0.36,0.16170025772532357
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.375757021660286,0.0019,0.0023,0.9077,0.0818,0.0033,0.003,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.34776106,49.0,7.5,41.5,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.943782987108415,0.0542,0.0001,0.3146,0.0378,0.0014,0.0006,0.5913,1.14,1.14,0.5878348176473546
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.630330503,34.25,18.75,45.0,2.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.395682961121367,0.03,0.0006,0.0837,0.0261,0.002,0.0013,0.8563,0.78,0.78,0.07403017792270697
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,5.746375559,22.0,30.0,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.264087336809195,0.0156,0.0014,0.0138,0.0104,0.0025,0.0031,0.9532,0.32,0.32,-0.5824979728365652
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.15734025,49.0,28.0,20.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.513054897080286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.812051718,44.61,24.89,27.94,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.470495282661489,0.009,0.0004,0.0178,0.0948,0.0017,0.0003,0.8762,1.05,1.05,0.45938365771619283
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,7.893697629,32.11,24.89,40.44,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.289088639014612,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,0.46,0.46,-0.38268505738809105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.08675917,49.0,18.75,31.25,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9684234452869465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.13512977,42.13,18.75,38.13,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.906015244966153,0.0128,0.0,0.028,0.0208,0.0006,0.0,0.9378,0.93,0.93,0.28811544447464355
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.43848511,45.61,13.64,38.19,2.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.525044141508806,0.0635,0.0002,0.2019,0.083,0.0009,0.0003,0.6502,1.5,1.5,1.1016394573720025
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.44748395,44.5,7.5,45.0,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4520190064939165,0.011,0.0005,0.3972,0.0536,0.0016,0.0009,0.5352,1.45,1.45,1.0302777018546903
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.57169095,49.0,30.0,20.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.868303385518459,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.009941019,34.5,30.0,32.5,3.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3476939555933765,0.0165,0.0,0.0427,0.0616,0.0035,0.0028,0.8728,0.42,0.42,-0.43977446180194085
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.301142352,39.36,24.89,34.19,1.56,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.629862798578463,0.0246,0.0,0.1245,0.0895,0.0015,0.0023,0.7576,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,6.525773643,24.0,30.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.732683506287051,0.006,0.0012,0.0205,0.0177,0.0008,0.0,0.9538,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.31765932,46.5,7.5,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.813809051099419,0.073,0.0,0.0373,0.0149,0.0,0.0,0.8748,1.01,1.01,0.40229425330234303
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.01888288,46.37,7.5,44.21,1.92,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.706823839714591,0.0145,0.0004,0.1165,0.019,0.0007,0.0011,0.8477,1.94,1.94,1.7296229059243498
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.30562834,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.73795129722191,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,1.9,1.9,1.6725335015104998
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,9.480986593,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.302712827954156,0.0455,0.0,0.324,0.073,0.0011,0.0012,0.5551,1.0,1.0,0.38802190219888055
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0253701689981931,0.00985209592098701,0.307949537646453,0.622300893638244,0.0174680522283724,0.0170592515677505,0.0,0.0,,
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O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.5827200571505,0.00757568328250189,0.00220510873539676,0.728025615125869,0.236446776884745,0.0226429923353559,0.00310382363613184,0.0,0.0011482099710543,0.0011482099710543,-0.7958927956755514
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.688867745009658,0.00599960547383456,0.00187471922407934,0.58725363712808,0.393842224090862,0.00908706069367491,0.00194275338946932,0.0,0.0005585876781053,0.0005585876781053,-0.7974661979200065
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0207124354254999,0.00767807173489595,0.560331852523788,0.3797189836544,0.0206003960524344,0.0109582606089812,0.0,0.0001489580680618,0.0001489580680618,-0.7985592911689305
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0084525958204246,0.00170600389954699,0.807774257087237,0.172171860632781,0.00851123850670424,0.00138404405330582,0.0,0.0052460712339961,0.0052460712339961,-0.7849576865630203
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0142965461163966,0.00273099369058116,0.2951874813445,0.196790510597468,0.00567584660232592,0.00900724719724339,0.476311374451485,0.0033203605888808,0.0033203605888808,-1.0344742729359027
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584559232083967,0.0426258503334726,0.000887127042175757,0.102099604743599,0.057196348771858,0.00222434780081794,0.00162961025671667,0.79333711105136,0.0465195426566469,0.0465195426566469,-0.972818883550547
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O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.572543683160998,0.000714997259249526,0.000661552142657172,0.125943320778554,0.801966162874089,0.0693146503097598,0.00139931663568972,0.0,0.0127373438778132,0.0127373438778132,-0.764967287060561
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.358502089626924,0.00147233862420237,0.00107405472963131,0.901430168335102,0.0923159134092667,0.00310160866776492,0.000605916234032228,0.0,0.0763434621140544,0.0763434621140544,-0.5952348831288257
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.3962992939606,0.00110223184180453,0.00161797426133587,0.963322201717795,0.0321995776177804,0.00129202117564397,0.000465993385639812,0.0,0.380376087923258,0.380376087923258,0.21607368094058316
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.351438552905858,0.00061802522712851,0.00208191419961706,0.00520107649990865,0.018780252186508,0.966671145724669,0.00664758616216931,0.0,0.0289886812604962,0.0289886812604962,-0.7216007267742771
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.544995462952021,0.00423798522906651,0.00360605985882706,0.0132163308359338,0.182768863634774,0.789078621894797,0.00709213854660109,0.0,0.0033387326299993,0.0033387326299993,-0.7900474039572776
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0123483310685072,0.00430719249252366,0.0429874465070588,0.751978605237179,0.174073814828135,0.0143046098665965,0.0,0.0005090956767902,0.0005090956767902,-0.7975982669188943
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.790487251761844,0.00153513483125764,0.00147931904743739,0.82338319944907,0.169033483447006,0.00378262362292623,0.000786239602302501,0.0,0.306009500746919,0.306009500746919,0.017627054049161966
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.842058839093973,0.00164287085070931,0.000659195379539964,0.94017588697419,0.0550751037989028,0.00183173459161262,0.000615208405045708,0.0,0.504231824712829,0.504231824712829,0.5465816969768794
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.572543683160998,0.0204881792124896,0.00996076677576078,0.024515683125648,0.0206076067733214,0.0213656753332114,0.0146396167476402,0.888422472031929,0.0035574041476412,0.0035574041476412,-1.0341359560461585
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.358502089626924,0.0789442718629389,0.000859220559164078,0.352513414289749,0.0167725689541561,0.00207992092629201,0.000939235620822743,0.547891367786878,0.128034152082589,0.128034152082589,-0.8564783709716817
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3962992939606,0.020589791219893,0.00221295822133462,0.77006639472807,0.0336156368936998,0.00141982059640497,0.000804331444027444,0.17129106689657,0.352623838360951,0.352623838360951,-0.5359360852935553
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,1.0,4.351438552905858,0.0518701933925729,0.031230151711712,0.196119602463562,0.0891250765615729,0.225998436967717,0.183312147304902,0.222344391597961,0.0006916766953858,0.0006916766953858,-1.0382260228827003
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.544995462952021,0.0318134391856252,0.0195739470918212,0.0658637908929555,0.0405146823853727,0.0383355214778253,0.0445803960220688,0.759318222944331,0.0007826107131428,0.0007826107131428,-1.0380962386598327
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0496007240706346,0.0248050760368446,0.125156740550784,0.0913290655906173,0.0605654916232193,0.0647609529825488,0.583781949145352,0.000319594239126,0.000319594239126,-1.0387570720282182
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.790487251761844,0.0660465509749711,0.000704686244275338,0.176882938102508,0.134254150019803,0.00301700767902668,0.00146559050061717,0.617629076478799,0.391796497651864,0.391796497651864,-0.4800274905879333
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.842058839093973,0.180962520579808,0.000840183131263393,0.0600498448220066,0.0139903797423045,0.00230022430813273,0.00221494849849946,0.739641898917986,0.515169720881209,0.515169720881209,-0.3039448947184272
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.48897339158558,0.000136174132145422,0.00212452688507234,0.811633900204502,0.179761878637886,0.00385751556458306,0.00248600457581157,0.0,0.767759892635294,0.767759892635294,1.24980418110703
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.675628649636653,0.00268100351583557,0.00240431632025112,0.142040711181502,0.523320437165769,0.324868931367264,0.00468460044937817,0.0,0.0241897161135915,0.0241897161135915,-0.7344067258409619
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.737600973168581,0.00157432110064945,0.00176844882817444,0.053765469363115,0.438156626388713,0.500533090562106,0.00420204375724176,0.0,0.0189624719731265,0.0189624719731265,-0.7483555838832638
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.48897339158558,0.0550309639531662,0.00234353835896855,0.320198252727196,0.282656133384496,0.0064798077198827,0.00202476215621646,0.331266541700075,1.20135127285815,1.20135127285815,0.6753975083349388
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.675628649636653,0.0418659426619505,0.0219153925677162,0.21668759621254,0.199875450362037,0.113029824089051,0.0495629458661235,0.357062848240582,0.0027707272238572,0.0027707272238572,-1.035258728972282
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.737600973168581,0.0234118812216689,0.0071462713755353,0.0426958781226752,0.0464078935005845,0.0346044033846598,0.0235967118628926,0.822136960531984,0.0055457738057274,0.0055457738057274,-1.0312980850577906
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00767358537807448,0.00233215653996207,0.0713684727707158,0.307444763898641,0.0172788380976704,0.00511228295653041,0.588789900358405,0.0063917829512014,0.0063917829512014,-1.0300906311016962
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.579236803961587,0.00833063062779389,0.00173987762429209,0.156651961849343,0.112205138324295,0.00895304009765426,0.00427289873828259,0.707846452738339,0.269390835357988,0.269390835357988,-0.6547291495189385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0158311033527607,0.00109353847138243,0.0200990623529318,0.00589717673503959,0.00332080816189693,0.00297802720282806,0.95078028372316,0.0070114291767852,0.0070114291767852,-1.0292062502525494
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,5.0755487449389,0.0138253404297663,0.00670375922221507,0.064918033729737,0.0310082272870404,0.0307691214666871,0.0156091189056244,0.83716639895893,0.0111434256880136,0.0111434256880136,-1.023308919755896
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.40280917385641,0.0144051248882893,0.000525788660297221,0.125667067331117,0.214373546599095,0.00410880851120861,0.00177167337754258,0.639147990632451,0.176512628889736,0.176512628889736,-0.7872881867764152
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00115119797114568,0.0003959818507672,0.0538124209539168,0.93604524664705,0.00736502972190904,0.00123012285521143,0.0,0.0261518819859255,0.0261518819859255,-0.7291707023316024
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.579236803961587,0.0010942059599737,0.000714578151988552,0.367034511120116,0.62078160479883,0.0079478856978032,0.00242721427128835,0.0,0.970510173989973,0.970510173989973,1.7908416411254202
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0376230130625874,0.00236009027623813,0.247039705692743,0.697452972603375,0.0104681865382628,0.00505603182679352,0.0,0.0013884403431976,0.0013884403431976,-0.7952517429011965
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,5.0755487449389,0.00873826813676438,0.00145112475939544,0.193065080283125,0.778197018798523,0.014433213681334,0.00411529434085825,0.0,0.165721665234437,0.165721665234437,-0.35672988242469916
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.40280917385641,0.00532422079532615,0.00061084449763591,0.522469676271313,0.459778984209221,0.00966894873803684,0.00214732548846694,0.0,0.161020662402855,0.161020662402855,-0.3692744698577941
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584763376210429,0.0318391346416656,0.000341552225113717,0.113678281409446,0.242279767731552,0.00387550619454475,0.000871625110337537,0.60711413268734,0.649833386251602,0.649833386251602,-0.11174818341388475
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.746322465743975,0.0548193142492001,0.000263362025026913,0.0902956804122817,0.160837629010128,0.00315355508353847,0.000739500993108033,0.689890958226717,1.16375238999006,1.16375238999006,0.6217350625958049
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.651385609785054,0.0172566765287249,0.00318344365411915,0.0712890876960715,0.171965068058214,0.0218135302099503,0.0115493777455846,0.702942816107335,0.00327405282427,0.00327405282427,-1.0345403650034368
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O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0047850951415261,0.000675911772575438,0.46069265034102,0.522359359837259,0.0109775121699624,0.00050947073765779,0.0,0.773205414607926,0.773205414607926,1.2643355117511204
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.633757642840004,0.00198911414189635,0.00126811595413123,0.543867583730296,0.438842770521552,0.0129988635137729,0.00103355213835123,0.0,1.98493053910539,1.98493053910539,4.497814051056962
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.609759638321899,0.00125031423153586,0.0004860362025215,0.538249539726811,0.445414640899446,0.0137801694455006,0.000819299494184621,0.0,0.291137444797345,0.291137444797345,-0.022058905064912687
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.392884144674663,0.00226285185388551,0.000562872305858137,0.731364439797527,0.256932619347553,0.00825451238600619,0.000622704309170273,0.0,1.82872279459479,1.82872279459479,4.080974968218046
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0442923458834068,0.00055452650331333,0.106459881295074,0.192526940733964,0.00311682882196998,0.000623042068808978,0.652426434693463,0.672431538902446,0.672431538902446,-0.07949530652163618
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.633757642840004,0.0374610013402809,0.0005350551106764,0.260855439538844,0.469905543128085,0.00469334055693451,0.000912093945676405,0.225637526379503,1.69276100831231,1.69276100831231,1.3767547363410753
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.609759638321899,0.0836645231428707,0.000419599806684375,0.0235684307001288,0.0712275212970175,0.00119681308497475,0.00178295859414992,0.818140153374174,0.426058290183635,0.426058290183635,-0.431127857343191
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.392884144674663,0.0512990735432809,0.000672189655491244,0.187343972483681,0.232187436433234,0.00314791870850824,0.00146679734452725,0.523882611831278,1.30784095113947,1.30784095113947,0.8273833160675146
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,17.78759767,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.751259891859986,0.00405799702984203,0.00225047224182105,0.719270208750414,0.257208699720685,0.0138718178214465,0.00334080443579049,0.0,1.25160610942024,1.25160610942024,2.540943835364252
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.666265285347902,0.00272982965803786,0.000172365352517303,0.498048022051036,0.479137442306018,0.0180316959727267,0.00188064465966415,0.0,0.155537169131505,0.155537169131505,-0.3839071266005448
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.904756125442696,0.00273286200255075,0.00260055069792003,0.431146257918051,0.50349018951458,0.0550138028095967,0.00501633705730229,0.0,0.021985308799366,0.021985308799366,-0.7402891686477768
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.733211535868975,0.00166528576158017,0.000176886038620712,0.205207225042143,0.750916028545382,0.0392720451710516,0.00276252944122191,0.0,0.120096690961961,0.120096690961961,-0.478479751420455
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O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.666265285347902,0.0567289157085495,0.00653348267008008,0.064839577285576,0.335055277453961,0.0144955694225392,0.0143736618741762,0.507973515585118,0.268311366051918,0.268311366051918,-0.6562698060131026
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.904756125442696,0.0248552898268163,0.0125192728735768,0.0725307642598596,0.0355254691282667,0.0214395648154144,0.0248745799236939,0.808255059172372,0.0741845243461588,0.0741845243461588,-0.9333344503561898
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O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.61880246,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.82374330878754,0.000875415234709484,0.00127375854285246,0.683377837104949,0.304003257921165,0.00820355561270421,0.00226617558361995,0.0,0.943420561172443,0.943420561172443,1.7185532318874628
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.433313679041901,0.000602190120987361,0.000576528881915898,0.00566197423128506,0.0161763859347042,0.971683265119797,0.00529965571131053,0.0,0.0305789310371634,0.0305789310371634,-0.7173571583105779
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.70929826,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.356324137321509,0.00187378052819512,0.00157654975652554,0.0163863796216318,0.0648246159165097,0.905280007427939,0.0100586667491993,0.0,0.003875136361479,0.003875136361479,-0.7886160150068647
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.17273956,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.440767129696481,0.00301049906217731,9.21592223531261e-05,0.00380096827414773,0.0130323481002541,0.97657327492354,0.00349075041752818,0.0,0.0274401441027376,0.0274401441027376,-0.7257329854571254
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.349632566862877,0.00273989274094748,0.00161018393061426,0.0112824839963327,0.0583352940699212,0.919247401685963,0.00678474357622127,0.0,0.0081601896883771,0.0081601896883771,-0.7771813854096181
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.90345652,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.662778498608405,0.00349315451118928,0.00171298178399312,0.037797325974731,0.242816837972913,0.706569889763285,0.00760980999388795,0.0,0.0136767051395404,0.0136767051395404,-0.7624606092513427
O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,0,0,1,,4.405498990859024,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,,4.815106909815019,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.562053894914463,0.00241700650155169,0.00189161759954923,0.0117804592312353,0.0588098364115177,0.918016488291877,0.0070845919642692,0.0,0.288385322760908,0.288385322760908,-0.029402920107978105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.667205576907544,0.00146771264056884,0.000853267380299107,0.00521853383313367,0.0984194458399351,0.890752405611161,0.00328863469490281,0.0,0.174730948641107,0.174730948641107,-0.3326886836733955
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.94799221,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.701389043728634,0.00256320924432886,0.00193796271600952,0.0128146756680969,0.0418402586947232,0.934553052894321,0.00629084078252029,0.0,0.0492674291707299,0.0492674291707299,-0.6674870545840368
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.38469122,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.460491174618648,0.00101051612937229,0.00153512067382825,0.00950098551353592,0.161931963893941,0.822835993399315,0.00318542039000704,0.0,0.105055900803977,0.105055900803977,-0.5186159763833679
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,19.0764718,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.505460341839079,0.00282763425766742,0.00135220428389579,0.101550310310828,0.701364372579719,0.18950529802972,0.00340018053817036,0.0,0.0700302222351868,0.0700302222351868,-0.6120817118766197
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.18453431,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.684905154006945,0.0025903109842197,0.00122267327648511,0.0959380417500791,0.558064631213231,0.339326541744348,0.00285780103163663,0.0,0.0836567108446898,0.0836567108446898,-0.5757195389760648
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.58497913,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.695924549256556,0.00270162630925447,0.000571977156802491,0.072649821877092,0.283620916967858,0.638520904456637,0.00193475323235631,0.0,0.108372702997361,0.108372702997361,-0.5097651169808466
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O,DSPC,0,0,1,0,16.82518306,48.5,10.0,40.0,1.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,LYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,4.202899968776446,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.52948326,43.25,25.0,30.0,1.75,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,5.029784112935016,0.000951862951033406,0.000642237882584555,0.00747953132811133,0.295137112679544,0.692754163229738,0.0030350919289883,0.0,0.19435393861906,0.19435393861906,-0.2803248961378029
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.10169345,30.0,25.0,42.5,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.833102254034098,0.00529626249319983,0.00246267213977097,0.0289260006923807,0.563065088278535,0.393847703229461,0.00640227316665243,0.0,0.049072760763369,0.049072760763369,-0.6680065256297026
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.72804315,38.075,17.975,41.825,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,,4.930148043183569,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.39261658,37.0,25.0,37.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.146912912388803,0.000759366167023555,0.000694817987152034,0.00466364025695932,0.212680085653105,0.777593147751606,0.00360894218415418,0.0,0.201238755105862,0.201238755105862,-0.2619528199077537
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.51039532,38.5,20.5,38.5,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.684905154006945,0.00157535225652128,0.00592927130077556,0.00900517890128691,0.366135503933579,0.613833328839362,0.00352136476847493,0.0,0.149329656900936,0.149329656900936,-0.40047182198750214
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.48290639,45.0,9.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.869839484130799,0.00147117555088917,0.000927103843315829,0.00585237061645294,0.136146016514374,0.851575135737455,0.00402819773751327,0.0,0.31219703699332,0.31219703699332,0.034138443686487704
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.13138042,41.2,22.35,34.325,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.901564199041894,0.00315707422768752,0.0025689389054212,0.0146712017391132,0.327849346901905,0.646061693847123,0.0056917443787501,0.0,0.158541375998041,0.158541375998041,-0.3758904252594646
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.11942242,41.825,14.975,41.825,1.375,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.039546637590676,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.79492927,45.0,22.5,30.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.9141243937154115,0.00113350028034128,0.000566939752127873,0.00680706926467914,0.502661298625749,0.486733894218144,0.00209729785895866,0.0,0.145448415448628,0.145448415448628,-0.4108288829150842
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,12.55393718,34.325,21.725,41.825,2.125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.814620410170298,0.001692878443667,0.000820135726038303,0.00868136575507882,0.408928448915581,0.577101122031978,0.00277604912765729,0.0,0.113760366510672,0.113760366510672,-0.495388181160095
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.93959861,45.0,7.5,45.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.527640983478854,0.00506334343919377,0.004281344333051,0.0165771717732586,0.226890591170162,0.736348900590883,0.0108386486934518,0.0,0.0547343765642327,0.0547343765642327,-0.6528985503803821
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.59337013,45.0,15.75,37.5,1.75,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.810557015713042,0.00141112235558708,0.000749767156842064,0.00637541161251223,0.138880841494329,0.847648476304751,0.00493438107597822,0.0,0.294154433878409,0.294154433878409,-0.0140080944893819
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.66031337,30.0,24.0,45.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.16763904290592,0.00199236267032557,0.000827577235394216,0.008719084857644,0.192132365846187,0.792330257640873,0.0039983517495764,0.0,0.151793984465988,0.151793984465988,-0.3938957841268362
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.66358165,37.5,15.0,45.0,2.5,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.618086411254637,0.00271480786609193,0.00181664538344774,0.00938513027274936,0.132547184736695,0.849509595736892,0.0040266360041233,0.0,0.0950036114384557,0.0950036114384557,-0.5454404279666308
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.26186294,45.0,24.0,30.0,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.098035484377089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.27611859,45.0,11.382,42.618,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.680277658474896,0.00152924607683628,0.00192508702614222,0.0105762053188716,0.167270255683968,0.810875386281306,0.00782381961287527,0.0,0.278754923842637,0.278754923842637,-0.05510156049896443
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.11001923,45.0,13.445,40.445,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.000999438616070677,0.00125158481927741,0.00771842730472846,0.249469737208587,0.735450494958472,0.00511031709286499,0.0,0.286455906115286,0.286455906115286,-0.03455155257492116
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.85662691,45.0,16.405,37.595,1.0,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.00141338619768439,0.00124322063420737,0.0100450891793794,0.235894751086175,0.745556785166654,0.00584676773589971,0.0,0.264336417833639,0.264336417833639,-0.09357722532293417
O=C(CN(CCCCCCCCCCCC)CCCCCCCCCCCC)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.44559484,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.892641641172089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCCCC,DSPC,0,0,1,0,15.24245185,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.345103280569283,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.310127759130018,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,16.95535314,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.35696520407851,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCC)CCCCCCCCCC)NCCCN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.51030189,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.175309921045206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.11860943,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.447697327163527,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,16.80841018,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.381651564343798,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,14.7769988,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.250350662548819,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.386765389021055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.55151343,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.391729410135267,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.85660447,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.114394528387108,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.63293083,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,5.272999558563747,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O,DSPC,0,0,1,0,16.2856483,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.28978103552575,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)NCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.23582504,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.260615499364025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)CN(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.75702627,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9788005705762375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.47477668,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.68213122712422,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,19.33366115,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.98780245,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.9473404437239425,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CO)=O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.42695266,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.545101659521972,0.0,0.00318490682025255,0.0608074236431031,0.251089505980848,0.00892095913117615,0.00601048706680474,0.669986717357815,0.0815243428420059,0.0815243428420059,-0.9228588036953479
CCCCCCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)=O)CO)CCCCCCCCCCCCCC,DSPC,0,0,1,0,16.68206611,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.844974178195408,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H]([C@H](O)C)N(CCCCCCCCCCCC)CCCCCCCCCCCC,DSPC,0,0,1,0,15.77114057,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,thr,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.331522502500114,0.0,0.0131160505661734,0.0817206877958181,0.209957462105326,0.0363069917919837,0.0161572104727098,0.642741597267989,0.0248953087459781,0.0248953087459781,-1.0036817494221935
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4135253017332525,0.0,0.00151329913495755,0.0471551068594211,0.0476760649180962,0.00182335320536251,0.00763287581452213,0.89419930006764,0.35502103370942,0.35502103370942,-0.5325147239258616
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.509649984130679,0.0,0.00235961766437825,0.513627015742916,0.0879412499947796,0.00175822838354556,0.00311254749811917,0.391201340716262,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.496359280129911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC,DSPC,0,0,1,0,14.13296737,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.170425586627436,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.445353484534206,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC,DSPC,0,0,1,0,15.1299087,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.166510173022286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.673109168996284,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC,DSPC,0,0,1,0,16.72728505,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.7572902340489245,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.000230328920605394,0.0259372790881254,0.0734981485145439,0.000576894596302152,0.000867946038939987,0.898889402841483,0.486446282346577,0.486446282346577,-0.34493999468492637
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.332573750954351,0.0,0.00183814880222334,0.508470854676458,0.479298868566087,0.00664368457868438,0.00374844337654761,0.0,0.0806697533656258,0.0806697533656258,-0.5836902104683951
O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,14.7050121,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.00446051681777838,0.0286140231457339,0.01484311836534,0.00629790100652696,0.01599114503205,0.929793295632571,0.0275210452544693,0.0275210452544693,-0.9999342060867568
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.7050121,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.577079305821566,0.0,0.0104002218216073,0.139229779861971,0.807246421461676,0.041233674188,0.00188990266674509,0.0,0.0040656278842911,0.0040656278842911,-0.7881076899433005
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.00711911642710361,0.153280595121264,0.136743424441396,0.0628412485834964,0.0734141937722642,0.566601421654476,0.0027486514420013,0.0027486514420013,-1.0352902363032352
O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.11494914,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.7535901911063645,0.0,0.106975953776871,0.247623902989694,0.292657465739291,0.229416263063982,0.123326414430162,0.0,0.001042320755636,0.001042320755636,-0.7961753601769197
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.789157022101107,0.0,0.0386975655052687,0.153034034478582,0.0799184464451532,0.0414429326981307,0.0607210626185958,0.626185958254269,0.0073827728841294,0.0073827728841294,-1.0286762554754216
O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC,DSPC,0,0,1,0,14.05354178,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,1,0,0,0,0.0,4.639571612705423,0.0,0.135531713474282,0.541180183023036,0.178510571158094,0.0949195329757021,0.0498579993688861,0.0,0.004009461265808,0.004009461265808,-0.7882575701032632
O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,15.91058453,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.639571612705423,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.000231298468169262,0.195828728849491,0.0126185833117857,0.000504922171493209,0.00109315352063243,0.789723313678428,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.391357962102766,0.0,0.00515447939315304,0.962574355010024,0.0304157301451643,0.000918038843316605,0.000937396608342438,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,,4.45295097301058,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0963955724315343,0.000259669027359828,0.0209585518067849,0.0324510369422159,0.00191021824445882,0.00526970020363582,0.84275525134401,0.95415067884307,0.95415067884307,0.32258414125816925
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.508769411701737,0.0,0.00301852406237983,0.561715155652109,0.427466534539213,0.00675382930885143,0.00104595643744612,0.0,0.469108231863161,0.469108231863161,0.4528546780295592
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.424367475163407,0.00431198097235812,0.000818950238891083,0.0696322838846972,0.0220758004851341,0.00177157151502323,0.00255208415951453,0.898837328744382,0.673380628639453,0.673380628639453,-0.07814073232611048
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.424367475163407,0.0,0.00336772556852765,0.856457049453334,0.133858740361315,0.00483749939645135,0.00147898522037143,0.0,0.274077344076178,0.274077344076178,-0.06758364367522034
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0465123735855303,0.000498926332937811,0.165458883776434,0.0565565738614754,0.00106294680997165,0.00247840641808945,0.727431889215561,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570475216191205,0.0,0.00167236193574396,0.848665421605967,0.144098339320739,0.00370843762360476,0.00185543951394526,0.0,1.0,1.0,1.8695349995476385
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0297656858896609,0.000244336475601744,0.00951547807887942,0.00817695885320599,0.000472306069630483,0.00458791238707824,0.947237322245943,0.549425262386022,0.549425262386022,-0.2550541831588352
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.570268133978827,0.0,0.00411439872497652,0.670601694270008,0.311096989874152,0.00850379747404768,0.00568311965681539,0.0,0.0620258136097327,0.0620258136097327,-0.6334414105302022
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC,DSPC,0,0,1,0,17.33731463,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC,DSPC,0,0,1,0,17.04310679,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.311727053457954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.00523681863830338,0.000823668079767528,0.00977318183991921,0.0124596675509096,0.00267973433328739,0.00363617950788083,0.965390750049932,0.316498770359056,0.316498770359056,-0.5874950507095055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.33700102,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.9082333604781745,0.0,0.010109099822305,0.45796731805265,0.507501663530466,0.0194068402228631,0.00501507837171616,0.0,0.0817828774610745,0.0817828774610745,-0.5807198479650095
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.590361070334383,0.00631834763893091,0.000504819647616299,0.140779687268235,0.0297514168337676,0.000617892126006545,0.0011394500617625,0.820888386423681,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.590361070334383,0.0,0.00283873189227405,0.901276452952094,0.0938738308613158,0.00141019974741145,0.000600784546904834,0.0,1.0,1.0,1.8695349995476385
O=C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)[C@H](C)N(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.63651378,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.442651256490317,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.530769863411841,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)CN(CCCCCCCCCC)CCCCCCCCCC,DSPC,0,0,1,0,14.88045619,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.48874872297084,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)CN(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.83327693,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.343844382133684,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.53889564,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.301494223781961,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.27376909,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.596939379038152,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0159262664008309,0.00726471746994425,0.0644691443511897,0.0154248397225439,0.00666778094817397,0.00618426236554005,0.884062988741777,0.163983867672707,0.163983867672707,-0.8051696746745034
O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC,DSPC,0,0,1,0,15.06368788,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.403665809777363,0.0,0.0110768066820314,0.679238145596264,0.289982439081482,0.0151104362851107,0.00459217235511197,0.0,0.0864824917721372,0.0864824917721372,-0.5681789657875123
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.285378059618076,0.00952025723585679,0.00424787112198889,0.0270494802958792,0.00951147065788185,0.00569809581675416,0.00864159943836194,0.935331225433277,0.22281247574214,0.22281247574214,-0.7212074197450102
O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC,DSPC,0,0,1,0,15.91176651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.285378059618076,0.0,0.00577401787332259,0.781123329740865,0.202386288853494,0.00852464019685452,0.00219172333546338,0.0,0.23688698835255,0.23688698835255,-0.16682580237138014
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.11033537,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,5.0106352940962555,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0307690543253117,0.000803846893528031,0.00327375890943859,0.00440309874760962,0.00131506681420977,0.00341198428561488,0.956023190024287,1.14370500641117,1.14370500641117,0.5931227328814345
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.49121730591206,0.0,0.0103006057269574,0.229208194092422,0.735779643429865,0.0182228400970524,0.00648871665370264,0.0,0.146101132843469,0.146101132843469,-0.40908711190961344
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.573885895948325,0.00305704097815131,0.00100491779320209,0.0165773259574103,0.0117710271412967,0.00208697129856503,0.00287252217431477,0.96263019465706,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.573885895948325,0.0,0.00330040832612047,0.545398801975274,0.446192251044312,0.00323782528214899,0.00187071337214386,0.0,1.0,1.0,1.8695349995476385
O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.79756457,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.789042318607025,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.40770989,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.168208681201016,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.93089479,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.697749367281185,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC,DSPC,0,0,1,0,16.38737682,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.2112383136936,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.61200662,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.27999390910873,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.611152257665639,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.1422481808981475,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.515354881665727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.57532934397707,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.451896454476337,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.2554924,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.925077405734609,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.391561,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.829912458665998,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC,DSPC,0,0,1,0,16.63400342,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421728001525434,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC,DSPC,0,0,1,0,17.25637024,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.775756486563625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC,DSPC,0,0,1,0,17.79833258,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.862341963516347,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.55042057,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,5.5506312951620265,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.34229222,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.47597224751641,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.30473405,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.563722996073918,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O,DSPC,0,0,1,0,16.11614863,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.275554390163365,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O,DSPC,0,0,1,0,16.80938411,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.35709336812867,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.32727581,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.473579765600494,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O,DSPC,0,0,1,0,17.03239796,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.5612182984589085,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.71577453,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.695924549256556,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O,DSPC,0,0,1,0,14.72351388,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.857484114602081,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O,DSPC,0,0,1,0,15.6246954,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.483228515182849,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O,DSPC,0,0,1,0,16.38850868,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.426521874560433,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O,DSPC,0,0,1,0,17.04402965,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.412919498116252,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.53558149,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.69866052907543,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.95535314,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.9459189793765646,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC,DSPC,0,0,1,0,13.97521151,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ala,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.450269224770129,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O,DSPC,0,0,1,0,17.46731585,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.659658371272161,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O,DSPC,0,0,1,0,16.8769168,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.139321635057579,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.04309994,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.283448621312786,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O,DSPC,0,0,1,0,17.76093253,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,gly,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1455128487965,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,18.07661492,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.3551691805039985,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,6.632923618509176,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-],DSPC,0,0,1,0,12.69438691,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TEA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.762173934797756,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0111914004572023,0.00227125491616379,0.00877931935589419,0.0082437061808303,0.00401873844514775,0.00849693826019724,0.956998642384564,0.596141429580998,0.596141429580998,-0.18837922911736
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.240751047315928,0.0,0.00531733106486159,0.69156525750989,0.28508003495893,0.0160312488066627,0.00200612765965623,0.0,0.176602424488684,0.176602424488684,-0.3276946657499996
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0210584248832937,0.000931640117614886,0.0300315170504259,0.0160360600660287,0.002060495753182,0.00519348457253804,0.924688377556917,0.507741968135695,0.507741968135695,-0.31454604422779553
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.89554445,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.253340627045836,0.0,0.00533934786984105,0.597844801683409,0.374278985337898,0.0199301473078145,0.00260671780103763,0.0,0.177860137006811,0.177860137006811,-0.3243384702286213
O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,18.15212729,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,8.664405571096625,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.498141613229568,0.00224222740615835,0.000962422246665562,0.00287219892799367,0.00322451176864607,0.00206661890626862,0.00333409585594076,0.985297924888327,0.792858557060483,0.792858557060483,0.0923823620278189
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.498141613229568,0.0,0.00657230701947091,0.556297397905001,0.404138164228711,0.0296624454205942,0.00332968542622302,0.0,0.20948041157182,0.20948041157182,-0.2399600273409918
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.462799844696365,0.0122002332749747,0.000591091003585345,0.00113975593374826,0.00176766182040017,0.00118628775621157,0.000814512180559894,0.98230045803052,1.58712844716331,1.58712844716331,1.2259922362734261
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.462799844696365,0.0,0.0055909076747788,0.864547542326111,0.121503978921508,0.00729914012568763,0.00105843095191469,0.0,0.762385942529413,0.762385942529413,1.2354638394013375
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0390763854278316,0.00164994009844252,0.0661192424915616,0.0206209930549816,0.00197347693054232,0.00160454285244798,0.868955419144192,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.196600262926448,0.0,0.00384316363496011,0.851255867494199,0.137210400166604,0.00701109092659647,0.000679477777641109,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.67788651,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.401951803481151,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCCCCCC)OCCCCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)CO)=O,DSPC,0,0,1,0,17.86915095,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.421487703554795,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O,DSPC,0,0,1,0,17.61285873,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.577593418217857,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCCC(OCCCCCCCCC)=O,DSPC,0,0,1,0,15.66191374,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DBU,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.647271362006727,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.541058240520847,0.0155523974922323,0.00129152518305059,0.446962380102849,0.0407067099579296,0.00170625578284345,0.00421830607343662,0.489562425407659,1.0,4.04718291807415,4.73706835052163
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.83323084,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.1751562049585145,0.127270779777207,0.0355651632001246,0.0965373529640882,0.0454740204097531,0.0338026797538366,0.0465840928565864,0.614765911038405,0.0505010966098528,0.0505010966098528,-0.9671362699547936
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.95682792,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.416186486320586,0.0275897803818406,0.0140220813902507,0.0611423332934752,0.0248626002542061,0.0133347505104052,0.0187510241318683,0.840297430037954,0.11103838626238,0.11103838626238,-0.8807353246775064
C=CCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)=O,DSPC,0,0,1,0,18.01719192,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.445588116163626,0.0250376334304389,0.00337885545037859,0.0517009582142691,0.0430146012578083,0.00350252056656834,0.00406753936383155,0.869297891716705,0.594087846809013,0.594087846809013,-0.19131017455153912
CCCCCCCCCCCC(OCCCCCCN(CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.28161356,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.381026134340298,0.00774884428490629,0.00205921183588078,0.0366644403250292,0.0113925424121347,0.00225130046176364,0.00414541402825956,0.935738246652026,0.903691788703443,0.903691788703443,0.2505674416217897
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.382151626862033,0.0281381236661192,0.00268792352252722,0.218417144486954,0.0369503427520482,0.00199553488006137,0.00289937744032574,0.708911553251965,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.83044719,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.199605072879594,0.0747106900577881,0.0465999615731367,0.107994265529626,0.0501322770872438,0.0448116344718523,0.0485065251769853,0.627244646103368,0.0685266977729659,0.0685266977729659,-0.9414094990897005
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.94795095,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.333755086000182,0.0109650973341036,0.00500301836333305,0.0209516607489436,0.00928876974106986,0.00498354505150691,0.00613733877720584,0.942670569983837,0.624112412102086,0.624112412102086,-0.14845806079238213
CCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCC)=O)=O,DSPC,0,0,1,0,17.64728116,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.333098961050458,0.0312031939311219,0.00665572714585857,0.0303955096845431,0.016483404133503,0.00703656560389733,0.0108270584446455,0.897398541056431,0.396247798437663,0.396247798437663,-0.4736744378197291
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.21401022,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,0.0,4.865224091322398,0.113993758795815,0.073640090558649,0.155999510493789,0.089181912745518,0.0778008933488344,0.0854800220277795,0.403903812029615,0.0331042054271613,0.0331042054271613,-0.991965723861604
O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.964966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.177279038170981,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.327834405590455,0.0791681309989092,0.00438236238399703,0.207450725009039,0.0200057324176319,0.00435501692886232,0.00687586277442937,0.677762169487131,1.0,1.0,0.38802190219888055
O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.01143435,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.826712455935327,0.051854991416453,0.0528002488161413,0.131177333337399,0.0608349367134925,0.0676316423389937,0.091080124286102,0.544620723091419,0.0058976768275302,0.0058976768275302,-1.0307958367096368
O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.98131005,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.613138355637268,0.0349404656939791,0.032170759570341,0.107989787547248,0.0410644871922655,0.0376181677387698,0.0487295770112475,0.697486755246149,0.0093821747742871,0.0093821747742871,-1.025822638898096
O=C([C@H](CO)N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,13.72220648,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.45318382899021,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,14.27012616,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,5.256453162449338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2,DSPC,0,0,1,0,15.19898065,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,pp,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.86830338551846,0.0353281775739917,0.00307182736960491,0.034716407488313,0.0124183147896963,0.00493000176115631,0.00714349716206655,0.902391773855171,0.291015633780908,0.291015633780908,-0.6238654779555869
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.260282639765531,0.0263012913083446,0.00104221918552839,0.17396331575752,0.0231252484593015,0.00218421226891195,0.00250493797184971,0.770878775048544,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.400848388914469,0.142104027989206,0.00287714799265922,0.215134204863943,0.0243152184566193,0.00619704480449007,0.00405451457231669,0.605317841320765,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN(CCN(C)CCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.06597416,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3551691805039985,0.0696417285874694,0.0029599268608454,0.0569405498935433,0.0189535946790038,0.00628554949471398,0.00620455647115851,0.839014094013266,1.46543205325214,1.46543205325214,1.0523028700808776
O=C(OCCCCCCN([C@H](C(NCCN(C)CCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.80021894,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.318154558079471,0.0260251149767627,0.00751090805185066,0.0532899531021804,0.0511794000344704,0.0152455710134586,0.0158624088727893,0.830886643948488,0.594741863231617,0.594741863231617,-0.19037673935045565
CCCCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)=O,DSPC,0,0,1,0,17.89376817,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.605170185988092,0.00991904799330563,0.00800736011391533,0.0452217049389508,0.0197202047147262,0.0164331186633441,0.0158205463682553,0.884878017207502,0.0777961107519447,0.0777961107519447,-0.9281798674338029
O=C(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.61561565,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.886582645426277,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN(CCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.01340623,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.190175207928333,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCN([C@H](C(NCCOCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.7439276,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2694176902912275,0.0273933363293668,0.0025481137083807,0.0489889660247262,0.00910395259986531,0.00553863037137659,0.00570731639004281,0.900719684576242,0.282511511559215,0.282511511559215,-0.6360028597730629
O=C(CCCCCCCCCCC)OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O,DSPC,0,0,1,0,18.18802872,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.561949483533528,0.0107761878140537,0.0018907931479914,0.00906874325536026,0.00817364202148832,0.00369121050409089,0.00412231341943734,0.962277109837578,1.03869430459932,1.03869430459932,0.44324777229346224
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CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,0,1,0,0,0.0,4.24735173134728,0.0,0.0193985055782088,0.642311593152982,0.297952931923085,0.0232690994142363,0.0170678699314884,0.0,0.0138284395356039,0.0138284395356039,-0.7620557072620823
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.776599301615622,0.0,0.00374237304524464,0.388696129733584,0.542462789676973,0.0600826887673663,0.00501601877683173,0.0,0.0757788640374704,0.0757788640374704,-0.5967415084575073
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.59784341060163,0.0,0.00454633850545055,0.547957057084188,0.42844914578143,0.0150324705651762,0.00401498806375593,0.0,0.0747683143174281,0.0747683143174281,-0.5994381520828621
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O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.684905154006945,0.0,0.00209231248329155,0.858334702447977,0.133879376324869,0.0038743559198132,0.0018192528240494,0.0,1.0,1.0,1.8695349995476385
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)C,DSPC,0,0,1,0,18.00540724,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.583231278469338,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)C,DSPC,0,0,1,0,17.73535311,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.224056168743758,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(CCCCC(OCCCCCCN(CCCNC([C@@H](N(CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CO)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)=O)OCCCC(F)(F)F,DSPC,0,0,1,0,18.72527826,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.972587226458726,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC,DSPC,0,0,1,0,17.8896653,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.363226005210164,0.0302618004269707,0.0170318389360463,0.0852511261606349,0.0321310738618372,0.020553836096385,0.0249767617646758,0.78979356275345,0.103578477209434,0.103578477209434,-0.8913823687978608
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCCCCCC,DSPC,0,0,1,0,17.93964861,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.27430221608671,0.0441668582339066,0.00173504332049564,0.0552287456296669,0.0103338721124601,0.00424436496446174,0.00798306414101548,0.876308051597994,0.118006736161235,0.118006736161235,-0.8707898510406828
O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C,DSPC,0,0,1,0,17.66483929,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.322011202263895,0.014374943627672,0.00199135248489222,0.0891563599260395,0.0109943655858212,0.00408170887074953,0.00721565797781185,0.872185611527014,0.120117219447052,0.120117219447052,-0.867777695195366
C=CCCCCCCCCC(OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O,DSPC,0,0,1,0,17.93091393,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.589955020181611,0.159505299591344,0.00863892692709962,0.059163494819016,0.0251436766117119,0.0207012928199433,0.0319161553971728,0.694931153833713,0.19624671777719,0.19624671777719,-0.7591230022455473
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.461068842013835,0.18227458966528,0.00260059752378256,0.10140002712747,0.0194272464327483,0.00394998811850684,0.00708234329707097,0.683265207835141,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,18.16832078,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.897839799950911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87291972,0.3296703297,0.2197802198,0.4395604396,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.667205576907544,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.34369997,0.41322314050000003,0.16528925619999998,0.41322314050000003,0.00826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.786658062033468,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.12329906,0.2702702703,0.32432432429999997,0.3783783784,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.520374534283375,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.602904588,0.25,0.4,0.3,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.2162671661789055,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.22342652,0.3846153846,0.2197802198,0.3846153846,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,4.634728988229636,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.21412129,0.4,0.3428571429,0.2285714286,0.028571428569999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.378896741664954,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.29890072,0.34653465349999996,0.396039604,0.2475247525,0.0099009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.661550519424199,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.62419529,0.4186046512,0.3720930233,0.1860465116,0.02325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.552612935249416,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,5.021245473208271,0.0189024787568605,0.00542838949966448,0.0161874266221436,0.00564673685028802,0.0063903753402389,0.0111802988958026,0.936264294035002,0.0913658402077254,0.0913658402077254,-0.908812673116613
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.59373115,0.3783783784,0.3783783784,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.484470400750307,0.220192249542946,0.000764987158036526,0.00117389921248248,0.000355328494502401,0.000727082388944626,0.00146163086877099,0.775324822334317,0.909323670538887,0.909323670538887,0.25860546111465654
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.02523135,0.35897435899999997,0.41025641030000004,0.20512820510000002,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.474947598938117,0.0634606467339624,0.00208550415241484,0.000693953783467295,0.000703971489002912,0.00107462659382075,0.00306678394465369,0.928914513302678,0.68813569412733,0.68813569412733,-0.057081784806354334
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.414493824811383,0.0115671522937999,0.000329262998462127,0.000782715410474643,0.000454168201139608,0.00050928396392566,0.0365052454816706,0.949852171650527,1.45919493888772,1.45919493888772,1.0434010414727322
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.50825332,0.5283018868,0.2641509434,0.1886792453,0.01886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573163389853005,0.0289504727873473,0.000587630380490671,0.00098172979734669,0.000247631664832521,0.000530890620697785,0.00148666967519347,0.967214975074092,1.18732779204068,1.18732779204068,0.6553827041429786
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.02959744,0.5090909091,0.2909090909,0.1818181818,0.01818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.424367475163407,0.01918176556647,0.0010650954164724,0.0022206234626453,0.00126505200881015,0.0010329415925789,0.00258134917445057,0.972653172778573,0.519739549496667,0.519739549496667,-0.29742267487018065
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.0526464,0.43243243239999996,0.32432432429999997,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.646312129319266,0.0173760673957131,0.000550323482827711,0.00231355504088989,0.000799250291024724,0.00171157517792979,0.00187915335599706,0.975370075255618,0.641975082983608,0.641975082983608,-0.12296382974571453
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.87880561,0.3902439024,0.3902439024,0.1951219512,0.0243902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.627909672957581,0.031425165165133,0.00121897501467252,0.00336392108926765,0.00273184674446895,0.00365496097119473,0.00253008289994281,0.95507504811532,0.292484943880311,0.292484943880311,-0.6217684269937327
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.72896002,0.41025641030000004,0.3076923077,0.2564102564,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.6141299273595635,0.00243290161785256,0.00374029360494432,0.00771109158226845,0.00256075951190699,0.0024473081411263,0.00398520450059787,0.977122441041304,0.29000081469118,0.29000081469118,-0.6253138633910964
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.2936051730729785,0.0291199872991734,0.000702410023626044,0.0253755412996204,0.0176881988849176,0.000962484515645204,0.00126799370807735,0.92488338426894,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.596835549198034,0.0642873127295256,0.000194616801396495,0.00548703707264694,0.0163820187916684,0.000849254927099769,0.000518055392084143,0.912281704285579,0.772854925639995,0.772854925639995,0.06383247693007311
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.26769266,0.3783783784,0.3783783784,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.284827171296749,0.000820324065776298,6.77505055763446e-05,0.00130838737685328,0.00203458073148474,0.00044026025400656,0.00179231955954145,0.993536377506761,0.647354606156059,0.647354606156059,-0.11528598539707118
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.69845587,0.35897435899999997,0.41025641030000004,0.20512820510000002,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.355939299910563,0.000606683031689403,0.000350488437662207,0.00200552330636915,0.00341592792036262,0.00135658595795651,0.00484812686613966,0.98741666447982,0.429472560198128,0.429472560198128,-0.42625489130230415
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.73864775,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.210051369934071,0.0506054803736383,0.000934742670841204,0.00195746112246746,0.00131704918881155,0.00229254534633995,0.00362188526923176,0.93927083602867,0.295296757118666,0.295296757118666,-0.6177553084162161
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.22254695,0.5283018868,0.2641509434,0.1886792453,0.01886792453,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.19614876167715,0.000394517913167851,0.000925918583325644,0.00219111536287718,0.00192843383777798,0.00141208216065332,0.00279803133939282,0.990349900802805,0.423957111788814,0.423957111788814,-0.43412673292138043
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.73562869,0.5090909091,0.2909090909,0.1818181818,0.01818181818,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.324000197151533,0.0149763371723649,9.09516394922477e-05,0.00865819492777344,0.00337158611087041,0.000870833891384162,0.00234291805381448,0.9696891782043,0.799987755503576,0.799987755503576,0.10255740435442702
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.73441264,0.43243243239999996,0.32432432429999997,0.21621621619999998,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.638604962074329,0.00412763242238728,0.000587351434637121,0.00125519721482213,0.00156835329887146,0.00151910105091065,0.00332452673735467,0.987617837841017,0.519710678404319,0.519710678404319,-0.29746388070685387
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.55362203,0.3902439024,0.3902439024,0.1951219512,0.0243902439,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.465448242812954,0.001908149535057,0.00051106883667359,0.00195557181028906,0.00222543526142979,0.00102554934782431,0.0036709617373884,0.988703263471338,0.559906246507883,0.559906246507883,-0.24009535462913364
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.4082575,0.41025641030000004,0.3076923077,0.2564102564,0.025641025640000002,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.439351701293151,0.0164941051995163,0.00133624924425635,0.0136411729141475,0.0068725438331318,0.00281561744256348,0.00565863059250302,0.953181680773882,0.404416041627467,0.404416041627467,-0.4620164343493942
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.348211286179151,0.25310386523031,0.000588156076259717,0.140706646889545,0.17621759673582,0.00218337900345845,0.000839731767209391,0.426360624297398,1.0,1.0,0.38802190219888055
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,17.98993052,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.574298522321004,0.0173152888243317,0.00170643426094864,0.0181271736370668,0.0103847448319841,0.00234708518590686,0.00464250497463967,0.945476768285122,0.880302275630684,0.880302275630684,0.21718510735044552
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.54771521,0.3296703297,0.2197802198,0.4395604396,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.530015512387331,0.0022188818222417,0.00151967168045253,0.0265741083102934,0.00935341146520975,0.00161955884356527,0.00594450434134348,0.952769863536894,0.693395601815244,0.693395601815244,-0.0495746598769834
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,16.03951812,0.41322314050000003,0.16528925619999998,0.41322314050000003,0.00826446281,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.640537329825382,0.0191565810814788,0.00120917820488213,0.00564887782228727,0.00368324602436162,0.00270413188019715,0.00625226385441887,0.961345721132374,0.702078866162311,0.702078866162311,-0.037181600128431615
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,10.8033785,0.2702702703,0.32432432429999997,0.3783783784,0.027027027029999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.2431955089544555,0.0191175904912105,0.0046774627841674,0.0253721583259607,0.0153479247605493,0.0105242912643767,0.0240873946993884,0.900873177674347,0.168910555827937,0.168910555827937,-0.7981381323616322
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,9.298704135,0.25,0.4,0.3,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.822697998516666,0.00783638212803346,0.00315432464612104,0.0156004284210389,0.0122536904537434,0.00649575798551451,0.014293561001533,0.940365855364016,0.26946434750834,0.26946434750834,-0.6546242303969191
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.90666525,0.3846153846,0.2197802198,0.3846153846,0.01098901099,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,5.291292751611072,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,13.89035919,0.4,0.3428571429,0.2285714286,0.028571428569999998,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.388753955423308,0.0457836478243602,0.00256820195313693,0.0933595380902435,0.040121791020458,0.00303459231576053,0.00719748271402532,0.807934746082015,0.638042293066864,0.638042293066864,-0.12857684559650717
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,12.97231927,0.34653465349999996,0.396039604,0.2475247525,0.0099009901,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.500031867864786,0.00367784574047392,0.00111977791364668,0.0109807451773001,0.00533981749985873,0.0035253353907892,0.00945759694134628,0.965898881336585,0.664597706735618,0.664597706735618,-0.09067602683869287
C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O,DOPE,1,0,0,0,14.30278396,0.4186046512,0.3720930233,0.1860465116,0.02325581395,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.578518154990665,0.00602415700375336,0.00352191807012307,0.0129438874596237,0.0112365957475355,0.00705054455561779,0.0163551166761144,0.942867780487232,0.387412476367661,0.387412476367661,-0.486284519689253
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DOPE,1,0,0,0,14.78083639,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.373742415086184,0.00132025329631253,0.000860633620224201,0.00503931327076771,0.0029913613071963,0.00270028184029275,0.0088532339643477,0.978234922700859,1.0,1.0,0.38802190219888055
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.434619084793052,0.00770185399584477,0.00244833711322221,0.0462111239750686,0.0198642411939162,0.00381226904350308,0.00922041774380283,0.910741756934642,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DSPC,0,0,1,0,11.7812451,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.485936098064394,0.00448668985970796,0.00155299888410839,0.00808200908228358,0.00771278024096098,0.00385266053622471,0.00536687174407294,0.968945989652641,1.22295554827804,1.22295554827804,0.7062318887477964
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.01459482,0.5490196078,0.2352941176,0.1960784314,0.01960784314,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.73444252169223,0.00221922165343577,0.00134658478491355,0.00928071520245763,0.0103471897935628,0.00308928870366618,0.00305991935175966,0.970657080510204,2.4848301850992,2.4848301850992,2.507223675274371
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.67100244,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.379899373657707,0.0165979002447495,0.00361970146585138,0.310566371988181,0.0118953898978584,0.00727497963461814,0.00647222326114303,0.643573433507598,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,18.26075368,0.5,0.1,0.385,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.7140245909001735,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.85564,0.309,0.363,0.259,0.069,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.002960000420248,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.10629825,0.337,0.322,0.28800000000000003,0.054000000000000006,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,,3.9917579734469997,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.076607527,0.215,0.44299999999999995,0.27399999999999997,0.067,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,4.150252194160397,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.262126773,0.285,0.369,0.233,0.114,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,,3.9384701754429945,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.14390228,0.47,0.40399999999999997,0.057,0.068,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,,4.139158578011894,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.465333240800292,0.0929588198875335,0.00109661539851913,0.0103406974639253,0.00262333547972377,0.00257373980843396,0.00319533888859958,0.887211453073265,2.49616154919077,2.49616154919077,2.5233961959539766
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,0.41,0.395,0.16,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.25063580654847,0.00217929592656579,0.00233573351378476,0.00718449647353577,0.00718369422949875,0.00471157922942054,0.00408542775852615,0.972319772868668,1.71461830076508,1.71461830076508,1.4079502315467747
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.40653622,0.31333300000000003,0.31333300000000003,0.31333300000000003,0.06,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.188896879163323,0.0142737392382439,0.00348189340868737,0.00880858320276677,0.0038525568856599,0.00593274588142816,0.00610316587084082,0.957547315512373,0.645718762121967,0.645718762121967,-0.11762071943757772
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,0.5,0.235,0.235,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.343935283551159,0.0065593281978378,0.00138907609400551,0.00613919753007927,0.00613411120238244,0.00366825953495706,0.00406194129869205,0.972048086142046,1.35219591573978,1.35219591573978,0.890688278863242
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.200348974,0.22,0.22,0.5,0.06,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.057161771094385,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.72417162,0.27,0.27,0.41,0.05,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,0,1,0,0,,4.102973888920155,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.092439729,0.16,0.395,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.127940511650616,0.0097349353786325,0.00823434520879355,0.0380775286515883,0.0189007253206434,0.0281939358827934,0.0273826912679074,0.869475838289641,0.161929321885153,0.161929321885153,-0.8081019945583146
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,0.395,0.16,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.116269119637892,0.00176070173692806,0.00134882241229812,0.00721447825021801,0.00277771416530431,0.00258248336542972,0.00338400053115958,0.980931799538662,0.834918279031508,0.834918279031508,0.15241147395626697
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.312676556539088,0.0122849683487715,0.00187692747865846,0.313004652084084,0.0267625511357853,0.00478000951875277,0.00400214034383056,0.637288751090117,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.5612182984589085,0.00230427148121394,0.00151653786120671,0.00981883965091339,0.0195498469521307,0.00278714514326426,0.00256552165624032,0.961457837255031,3.54213716664653,3.54213716664653,4.0162493217529285
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,13.95064466,0.41,0.395,0.16,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.2756934238792645,0.00339636246099529,0.00439836397767252,0.00922438120812044,0.0070906355917358,0.00777777401057153,0.0070228258793507,0.961089656871554,1.60048193764837,1.60048193764837,1.2450508067393784
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.77836699,0.5,0.235,0.235,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.300138475201197,0.0251900613139205,0.0263858529561065,0.0690244086529141,0.0290319859464883,0.0512059292322219,0.0395084822769767,0.759653279621372,0.244442812501583,0.244442812501583,-0.6903358436733202
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.93804335,0.395,0.16,0.41,0.035,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.035478809355064,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.314416735011824,0.00832740543716945,0.00279899792781369,0.0133506530995165,0.00590470004845411,0.00800781451355169,0.00611088774111073,0.955499541232384,1.4036171732161,1.4036171732161,0.9640785029516001
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,12.46964291,0.32299999999999995,0.32299999999999995,0.32299999999999995,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.122932019074013,0.00935369123549862,0.00681432683334856,0.0266295187790274,0.0091342786879667,0.0148394527045059,0.0109795829907811,0.922249148768872,0.807897092094877,0.807897092094877,0.11384588723707807
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,0,1,0,0,0.0,4.214347354616797,0.00175971204953205,0.0023945553766021,0.00864096914216858,0.00287247113967731,0.00354165273920712,0.00438932700137801,0.976401312551435,2.1807873939408,2.1807873939408,2.073283128685432
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.297557478047431,0.0163588203416613,0.0050349858804786,0.141665503002976,0.0268932928836599,0.0108166459136593,0.00842178986187252,0.790808962115693,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.623991940228679,0.0114998638575461,0.00130788860611426,0.00505223783079306,0.0046933168158669,0.00183202266239377,0.00287251942980201,0.972742150797484,1.19732008331576,1.19732008331576,0.6696440530835793
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.47398367,0.415,0.405,0.16,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.261975403606051,0.0120973279883405,0.00779128029381303,0.0260350268299895,0.0160802201335602,0.0156019499205845,0.0170739234476819,0.90532027138603,0.213285375768679,0.213285375768679,-0.7348048313269125
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.72570651,0.405,0.16,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.168678699274804,0.00644850088058007,0.00798921970887525,0.0221223520376599,0.0111631004951633,0.0106463671035197,0.00996963598739929,0.931660823786802,0.29077874869216,0.29077874869216,-0.6242035686713655
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.63764671,0.415,0.405,0.165,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.40562108352751,0.0088141667427258,0.00585903666298478,0.0157870816204507,0.010986042994209,0.00978368783097364,0.0102623946891479,0.938507589459508,0.370029347989408,0.370029347989408,-0.5110943308383519
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.402441819416474,0.154933534385178,0.00229861102597737,0.00525615721273492,0.00408539799683711,0.0022876287732977,0.00287249757879639,0.828266173027179,1.34933481107146,1.34933481107146,0.88660480982624
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.91076362,0.42,0.405,0.165,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.607168188650764,0.0408588610755303,0.0177373482989948,0.0425327283385076,0.0277718677406049,0.0276871974121274,0.0218927074965806,0.821519289637654,0.158736230637426,0.158736230637426,-0.8126592864976097
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.4277167605909975,0.00307921600642319,0.00224989559352084,0.00599370029233814,0.00443157985269048,0.00263031532778781,0.00293093049696406,0.978684362430275,1.27822314397057,1.27822314397057,0.785111741784596
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.444179499895966,0.0412236553892641,0.00390663231476925,0.121517080143859,0.0188177267921366,0.00482332620655526,0.0073631886059774,0.802348390547439,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,17.98206341,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.573473099244837,0.00689869445402741,0.00600089779665737,0.0191135089301672,0.00620664286397134,0.00981653359048003,0.0097967903769499,0.942166931987747,0.749333285576466,0.749333285576466,0.030261566378477555
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.88644869,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.688591794127164,0.00886147101476089,0.00436553876298869,0.0150948084008648,0.00476112441477112,0.00826588994437132,0.00836456609804533,0.950286601364198,0.883781845590108,0.883781845590108,0.22215127176544153
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.877221176,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.829113417472866,0.00517423746484337,0.00420818785762778,0.0136338012801862,0.00389526355348657,0.0081026937251479,0.00825574629036951,0.956730069828339,1.02766134878372,1.02766134878372,0.4275011503825392
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,14.07835597,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4595662121293,0.025369932029363,0.00629969301959379,0.0185849502075566,0.00668329267445478,0.00984673129800659,0.00995848867776924,0.923256912093256,0.773367707896157,0.773367707896157,0.06456433777003012
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,9.306031912,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.528073135603124,0.00974026247143072,0.00459547921939943,0.0155882894773368,0.00424301614179951,0.00735125258984654,0.00918675243548622,0.949294947664701,0.925634770529548,0.925634770529548,0.28188523570969626
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,6.950074466,0.41,0.4,0.16,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.730921391293652,0.0307398296858454,0.00502448817507942,0.0144391987292623,0.00475975114719379,0.00732990645958348,0.00864531856689022,0.929061507236145,0.282355212986546,0.282355212986546,-0.6362259345836732
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.3578620076745835,0.0575651939642587,0.00224327504140443,0.293214190330324,0.103801109257072,0.00316596887134689,0.00243404296405076,0.537576219571543,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.1515122352784415,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.2656332579940335,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.431173877940127,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.436396441739405,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.5666372362713075,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,,4.765586907393996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.23312059,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.149936935645806,0.0412282002133458,0.00282906106065428,0.0100452919302821,0.00294646346634102,0.0035555046437446,0.00510039590268196,0.93429508278295,2.31132936702855,2.31132936702855,2.259597216050143
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.0693509,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.244200317766478,0.0307672106546614,0.0492440442693678,0.143087600825361,0.0409904333145751,0.0410729694241231,0.0628737572688051,0.631963984243106,0.159668526820479,0.159668526820479,-0.8113286806519148
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.52014814,0.4,0.16,0.41,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.430459592195472,0.0144382835185698,0.030629687100469,0.0904231657039977,0.0327120644783899,0.0374915496460484,0.0408664371206098,0.753438812431916,0.342029093157046,0.342029093157046,-0.551057277633741
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,15.89020107,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.560277417097355,0.064087583051715,0.00731756531038673,0.0186036957891068,0.0053871458118381,0.00655845861152129,0.0086069303650773,0.889438621060355,2.14638048731397,2.14638048731397,2.024176383509215
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,10.50369223,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.667205576907544,0.00310349569550498,0.00416831577034203,0.0115025538737423,0.00349250282837259,0.00500126547712412,0.00690260249517487,0.965829263859739,3.35844880423818,3.35844880423818,3.754082841561727
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,7.844529643,0.405,0.165,0.415,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.713127327493184,0.00089376253365906,0.00183788568066981,0.0054363636464257,0.00195410248071216,0.00225811087193407,0.00383533887250888,0.98378443591409,3.24722414573894,3.24722414573894,3.595339103815341
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.359653205696989,0.0828383439279835,0.00565653685524585,0.157248489872984,0.00928479521934879,0.00688752099561758,0.00841921269728692,0.729665100431533,1.0,1.0,0.38802190219888055
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,16.86872188,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.634728988229636,0.00818072805535472,0.00273349879854757,0.0119346096951512,0.0075308964437597,0.00591367796700706,0.00578329104170321,0.957923297998477,0.213428398303373,0.213428398303373,-0.7346007045438266
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,11.15051107,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.7140245909001735,0.0160361616147136,0.00185083446366488,0.00730973501824061,0.00349956550575257,0.00416153151105757,0.00426975100661699,0.962872420879954,0.319359456002154,0.319359456002154,-0.5834121797200126
CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O,DOPE,1,0,0,0,8.327596879,0.49,0.25,0.24,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ser,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,0.0,4.822697998516666,0.0208671125611406,0.0200298903914976,0.0765668274895919,0.0297655881927753,0.0442427715485906,0.0417155046265625,0.766812305189841,0.0431568482237034,0.0431568482237034,-0.9776182391106099
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.548282323781043,0.235642631118293,0.00357683071882224,0.268183756367962,0.0537803810677977,0.0056567696761597,0.00550191880428196,0.427657712246684,1.0,1.0,0.38802190219888055
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.41834022,0.5,0.075,0.415,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.892602227184663,0.0004,0.0007,0.8627,0.1335,0.0019,0.0008,0.0,0.33,0.33,0.08164550420240263
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.34376213,0.5,0.29,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.935911747900319,0.0015,0.0017,0.585,0.3856,0.0215,0.0046,0.0,0.09,0.09,-0.5587925239809655
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.47881241,0.455,0.075,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.657762636107262,0.0008,0.0009,0.9399,0.0565,0.0012,0.0006,0.0,0.26,0.26,-0.10514892068441307
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.58994389,0.5,0.1775,0.3025,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6520537718869415,0.0009,0.0008,0.8853,0.11,0.0021,0.0009,0.0,0.31,0.31,0.028275668520455245
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.356515817,0.38,0.3,0.3,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.522874943261261,0.0008,0.0012,0.7508,0.2416,0.0048,0.0008,0.0,0.12,0.12,-0.4787377704580445
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.211083767,0.38,0.16,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.802380355275797,0.0003,0.0007,0.8979,0.0985,0.0022,0.0005,0.0,0.45,0.45,0.40186451829408665
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.891852481,0.38,0.23,0.38,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.721173861744398,0.0003,0.0009,0.9061,0.0898,0.0024,0.0005,0.0,0.3,0.3,0.0015907506794815506
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.59856338,0.4596,0.2483,0.2671,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.599152113662528,0.0006,0.0011,0.8386,0.1563,0.0028,0.0007,0.0,0.36,0.36,0.16170025772532357
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.516252746,0.4458,0.19329999999999997,0.3308,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.539030383483547,0.0011,0.0009,0.9163,0.0784,0.0025,0.0008,0.0,0.24,0.24,-0.15851875636636045
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.79855736,0.5,0.075,0.395,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.602165676967792,0.0007,0.0007,0.9622,0.0349,0.001,0.0005,0.0,0.91,0.91,1.6293707389788754
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.789158454,0.425,0.3,0.245,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.506454213048934,0.0013,0.0022,0.7003,0.2848,0.009,0.0025,0.0,0.1,0.1,-0.5321076061399918
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.924427289,0.4471,0.1358,0.3921,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.543294782270004,0.0006,0.0008,0.9464,0.0496,0.0015,0.0011,0.0,0.56,0.56,0.6953986145447971
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.213203287,0.4146,0.2483,0.3221,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.600157644164547,0.0006,0.0011,0.9277,0.0684,0.0014,0.0008,0.0,0.44,0.44,0.37517960045311294
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.766920469,0.38,0.14,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.380775852772229,0.0005,0.001,0.9807,0.0157,0.0015,0.0006,0.0,0.46,0.46,0.42854943613506036
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.9150442,0.5,0.27,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.490881039585964,0.0013,0.001,0.7257,0.2649,0.0061,0.0009,0.0,0.13,0.13,-0.4520528526170708
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.33144164,0.47240000000000004,0.1119,0.3887,0.0271,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.627909672957581,0.0073,0.0639,0.7768,0.1461,0.0042,0.0016,0.0,1.3,1.3,2.670082534776849
OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.92222847,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.8543712716215905,0.001,0.001,0.8647,0.1302,0.0025,0.0007,0.0,0.25,0.25,-0.13183383852538677
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.314817884980432,0.0009,0.0007,0.9116,0.0844,0.0018,0.0006,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.42041204,0.49,0.075,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.534747721691546,0.0013,0.0021,0.5194,0.4632,0.0111,0.0029,0.0,0.5,0.5,0.535289107498955
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,15.70987342,0.3425,0.1875,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.191168746857641,0.0011,0.0011,0.7685,0.2222,0.0053,0.0018,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,11.2192693,0.22,0.3,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0028,0.0014,0.4022,0.5806,0.0101,0.003,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.76101632,0.49,0.28,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.154184562578117,0.001,0.0012,0.5862,0.3912,0.0188,0.0017,0.0,0.16,0.16,-0.37199809909414977
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.31421044,0.4461,0.2489,0.27940000000000004,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.155753190350744,0.0041,0.0015,0.5886,0.3825,0.0211,0.0022,0.0,0.13,0.13,-0.4520528526170708
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.60470229,0.3211,0.2489,0.4044,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.104294893075269,0.0017,0.0016,0.5892,0.3913,0.0129,0.0033,0.0,0.05,0.05,-0.6655321953448602
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.00750041,0.49,0.1875,0.3125,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0111,0.0048,0.1796,0.7293,0.0671,0.0082,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.77390107,0.4213,0.1875,0.38130000000000003,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.33204826486764,0.0167,0.0049,0.2598,0.6793,0.0289,0.0104,0.0,0.15,0.15,-0.3986830169351235
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.21646499,0.4561,0.1364,0.38189999999999996,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.365643155423357,0.0042,0.0015,0.3443,0.6172,0.0298,0.003,0.0,0.2,0.2,-0.2652584277302551
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27353562,0.445,0.075,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.436751534363128,0.0067,0.0013,0.5909,0.385,0.0142,0.0019,0.0,0.22,0.22,-0.21188859204830776
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.27759176,0.49,0.3,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.151039905898646,0.0122,0.0028,0.2395,0.6818,0.0594,0.0044,0.0,0.08,0.08,-0.5854774418219391
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,14.75114553,0.345,0.3,0.325,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.248495242049359,0.0029,0.0024,0.3338,0.6429,0.0151,0.0029,0.0,0.07,0.07,-0.6121623596629128
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.61008,0.3936,0.2489,0.3419,0.015600000000000001,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.384523514872469,0.0141,0.0106,0.3243,0.5845,0.0592,0.0073,0.0,0.14,0.14,-0.4253679347760971
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,12.46688772,0.24,0.3,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.796616650559047,0.0064,0.0026,0.3777,0.6006,0.0093,0.0034,0.0,0.1,0.1,-0.5321076061399918
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.37981918,0.465,0.075,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.516338972281476,0.0024,0.0028,0.4642,0.5174,0.0093,0.0039,0.0,0.81,0.81,1.362521560569139
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,16.04448224,0.3736,0.2994,0.3171,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.370712874773608,0.033,0.008,0.1094,0.8115,0.0325,0.0056,0.0,0.11,0.11,-0.5054226882990182
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.623010104116422,0.0087,0.0033,0.2348,0.7393,0.011,0.003,0.0,0.36,0.36,0.16170025772532357
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,14.343031,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.375757021660286,0.0019,0.0023,0.9077,0.0818,0.0033,0.003,0.0,1.0,1.0,1.8695349995476385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.34776106,0.49,0.075,0.415,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.943782987108415,0.0542,0.0001,0.3146,0.0378,0.0014,0.0006,0.5913,1.14,1.14,0.5878348176473546
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.630330503,0.3425,0.1875,0.45,0.02,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.395682961121367,0.03,0.0006,0.0837,0.0261,0.002,0.0013,0.8563,0.78,0.78,0.07403017792270697
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,5.746375559,0.22,0.3,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.264087336809195,0.0156,0.0014,0.0138,0.0104,0.0025,0.0031,0.9532,0.32,0.32,-0.5824979728365652
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.15734025,0.49,0.28,0.2,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,1,0,0,1,0,0,0,,4.513054897080286,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.812051718,0.4461,0.2489,0.27940000000000004,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.470495282661489,0.009,0.0004,0.0178,0.0948,0.0017,0.0003,0.8762,1.05,1.05,0.45938365771619283
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,7.893697629,0.3211,0.2489,0.4044,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.289088639014612,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,0.46,0.46,-0.38268505738809105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.08675917,0.49,0.1875,0.3125,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.9684234452869465,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.13512977,0.4213,0.1875,0.38130000000000003,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.906015244966153,0.0128,0.0,0.028,0.0208,0.0006,0.0,0.9378,0.93,0.93,0.28811544447464355
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.43848511,0.4561,0.1364,0.38189999999999996,0.0256,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.525044141508807,0.0635,0.0002,0.2019,0.083,0.0009,0.0003,0.6502,1.5,1.5,1.1016394573720025
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.44748395,0.445,0.075,0.45,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.4520190064939165,0.011,0.0005,0.3972,0.0536,0.0016,0.0009,0.5352,1.45,1.45,1.0302777018546903
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,10.57169095,0.49,0.3,0.2,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.86830338551846,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,8.009941019,0.345,0.3,0.325,0.03,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.3476939555933765,0.0165,0.0,0.0427,0.0616,0.0035,0.0028,0.8728,0.42,0.42,-0.43977446180194085
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,9.301142352,0.3936,0.2489,0.3419,0.015600000000000001,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,4.629862798578463,0.0246,0.0,0.1245,0.0895,0.0015,0.0023,0.7576,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,6.525773643,0.24,0.3,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.732683506287051,0.006,0.0012,0.0205,0.0177,0.0008,0.0,0.9538,0.44,0.44,-0.41122975959501595
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.31765932,0.465,0.075,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.81380905109942,0.073,0.0,0.0373,0.0149,0.0,0.0,0.8748,1.01,1.01,0.40229425330234303
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.01888288,0.4637,0.075,0.4421,0.0192,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.706823839714591,0.0145,0.0004,0.1165,0.019,0.0007,0.0011,0.8477,1.94,1.94,1.7296229059243498
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,11.30562834,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.73795129722191,0.0343,0.0003,0.1697,0.027,0.0013,0.0009,0.7666,1.9,1.9,1.6725335015104998
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO,DSPC,0,0,1,0,9.480986593,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,Crtl,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.302712827954156,0.0455,0.0,0.324,0.073,0.0011,0.0012,0.5551,1.0,1.0,0.38802190219888055
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0253701689981931,0.00985209592098701,0.307949537646453,0.622300893638244,0.0174680522283724,0.0170592515677505,0.0,0.0,,
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584559232083967,0.00894763570081526,0.00182903773179144,0.430416319953847,0.549730482792046,0.00757886856613304,0.0014976552553668,0.0,0.0019532059842532,0.0019532059842532,-0.793744670428099
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.5827200571505,0.00757568328250189,0.00220510873539676,0.728025615125869,0.236446776884745,0.0226429923353559,0.00310382363613184,0.0,0.0011482099710543,0.0011482099710543,-0.7958927956755514
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.6888677450096585,0.00599960547383456,0.00187471922407934,0.58725363712808,0.393842224090862,0.00908706069367491,0.00194275338946932,0.0,0.0005585876781053,0.0005585876781053,-0.7974661979200065
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0207124354254999,0.00767807173489595,0.560331852523788,0.3797189836544,0.0206003960524344,0.0109582606089812,0.0,0.0001489580680618,0.0001489580680618,-0.7985592911689305
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0084525958204246,0.00170600389954699,0.807774257087237,0.172171860632781,0.00851123850670424,0.00138404405330582,0.0,0.0052460712339961,0.0052460712339961,-0.7849576865630203
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,17.88551615,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.763028270603671,0.0142965461163966,0.00273099369058116,0.2951874813445,0.196790510597468,0.00567584660232592,0.00900724719724339,0.476311374451485,0.0033203605888808,0.0033203605888808,-1.0344742729359027
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,17.94390528,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584559232083967,0.0426258503334726,0.000887127042175757,0.102099604743599,0.057196348771858,0.00222434780081794,0.00162961025671667,0.79333711105136,0.0465195426566469,0.0465195426566469,-0.972818883550547
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,18.3291697,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.5827200571505,0.0182648912592805,0.000462867676668248,0.083073077462289,0.0429608616930204,0.00195825764287227,0.000923423624969053,0.852356620640901,0.0509209522037464,0.0509209522037464,-0.9665370373099135
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,18.38109198,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.6888677450096585,0.0068908069603713,0.000629547873998548,0.021394314943629,0.042448777163022,0.00198708372142952,0.00248444060475972,0.92416502873279,0.016201262972428,0.016201262972428,-1.0160901968011615
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1,DSPC,0,0,1,0,19.03103458,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.374372415737022,0.0116932676375475,0.00103739027764326,0.0525071135910941,0.0215477599193875,0.00368874758435242,0.00400972460855577,0.905515996381419,0.006104461793755,0.006104461793755,-1.0305007059455489
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1,DSPC,0,0,1,0,19.07349618,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ML,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.567572155572773,0.0237911981258413,0.00067207203055979,0.18334881014348,0.0466442684044473,0.00188246389345958,0.000953648344707904,0.742707539057504,0.0550488822731985,0.0550488822731985,-0.9606455105817374
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.572543683160998,0.000714997259249526,0.000661552142657172,0.125943320778554,0.801966162874089,0.0693146503097598,0.00139931663568972,0.0,0.0127373438778132,0.0127373438778132,-0.764967287060561
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.358502089626924,0.00147233862420237,0.00107405472963131,0.901430168335102,0.0923159134092667,0.00310160866776492,0.000605916234032228,0.0,0.0763434621140544,0.0763434621140544,-0.5952348831288257
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.396299293960601,0.00110223184180453,0.00161797426133587,0.963322201717795,0.0321995776177804,0.00129202117564397,0.000465993385639812,0.0,0.380376087923258,0.380376087923258,0.21607368094058316
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.351438552905858,0.00061802522712851,0.00208191419961706,0.00520107649990865,0.018780252186508,0.966671145724669,0.00664758616216931,0.0,0.0289886812604962,0.0289886812604962,-0.7216007267742771
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.544995462952021,0.00423798522906651,0.00360605985882706,0.0132163308359338,0.182768863634774,0.789078621894797,0.00709213854660109,0.0,0.0033387326299993,0.0033387326299993,-0.7900474039572776
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0123483310685072,0.00430719249252366,0.0429874465070588,0.751978605237179,0.174073814828135,0.0143046098665965,0.0,0.0005090956767902,0.0005090956767902,-0.7975982669188943
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.790487251761845,0.00153513483125764,0.00147931904743739,0.82338319944907,0.169033483447006,0.00378262362292623,0.000786239602302501,0.0,0.306009500746919,0.306009500746919,0.017627054049161966
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.842058839093973,0.00164287085070931,0.000659195379539964,0.94017588697419,0.0550751037989028,0.00183173459161262,0.000615208405045708,0.0,0.504231824712829,0.504231824712829,0.5465816969768794
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.82491214,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GLN,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.572543683160998,0.0204881792124896,0.00996076677576078,0.024515683125648,0.0206076067733214,0.0213656753332114,0.0146396167476402,0.888422472031929,0.0035574041476412,0.0035574041476412,-1.0341359560461585
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.91081918,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,BIM,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.358502089626924,0.0789442718629389,0.000859220559164078,0.352513414289749,0.0167725689541561,0.00207992092629201,0.000939235620822743,0.547891367786878,0.128034152082589,0.128034152082589,-0.8564783709716817
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81357262,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3FLA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.396299293960601,0.020589791219893,0.00221295822133462,0.77006639472807,0.0336156368936998,0.00141982059640497,0.000804331444027444,0.17129106689657,0.352623838360951,0.352623838360951,-0.5359360852935553
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,1.0,4.351438552905858,0.0518701933925729,0.031230151711712,0.196119602463562,0.0891250765615729,0.225998436967717,0.183312147304902,0.222344391597961,0.0006916766953858,0.0006916766953858,-1.0382260228827003
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,IZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.544995462952021,0.0318134391856252,0.0195739470918212,0.0658637908929555,0.0405146823853727,0.0383355214778253,0.0445803960220688,0.759318222944331,0.0007826107131428,0.0007826107131428,-1.0380962386598327
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.80884374,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PY,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.237000862623624,0.0496007240706346,0.0248050760368446,0.125156740550784,0.0913290655906173,0.0605654916232193,0.0647609529825488,0.583781949145352,0.000319594239126,0.000319594239126,-1.0387570720282182
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.790487251761845,0.0660465509749711,0.000704686244275338,0.176882938102508,0.134254150019803,0.00301700767902668,0.00146559050061717,0.617629076478799,0.391796497651864,0.391796497651864,-0.4800274905879333
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DOPE,1,0,0,0,17.10338647,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.842058839093973,0.180962520579808,0.000840183131263393,0.0600498448220066,0.0139903797423045,0.00230022430813273,0.00221494849849946,0.739641898917986,0.515169720881209,0.515169720881209,-0.3039448947184272
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.48897339158558,0.000136174132145422,0.00212452688507234,0.811633900204502,0.179761878637886,0.00385751556458306,0.00248600457581157,0.0,0.767759892635294,0.767759892635294,1.24980418110703
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.675628649636653,0.00268100351583557,0.00240431632025112,0.142040711181502,0.523320437165769,0.324868931367264,0.00468460044937817,0.0,0.0241897161135915,0.0241897161135915,-0.7344067258409619
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.737600973168581,0.00157432110064945,0.00176844882817444,0.053765469363115,0.438156626388713,0.500533090562106,0.00420204375724176,0.0,0.0189624719731265,0.0189624719731265,-0.7483555838832638
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.07758774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OH,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.48897339158558,0.0550309639531662,0.00234353835896855,0.320198252727196,0.282656133384496,0.0064798077198827,0.00202476215621646,0.331266541700075,1.20135127285815,1.20135127285815,0.6753975083349388
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.50454535,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,ALA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.675628649636653,0.0418659426619505,0.0219153925677162,0.21668759621254,0.199875450362037,0.113029824089051,0.0495629458661235,0.357062848240582,0.0027707272238572,0.0027707272238572,-1.035258728972282
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.59671966,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,SER,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.737600973168581,0.0234118812216689,0.0071462713755353,0.0426958781226752,0.0464078935005845,0.0346044033846598,0.0235967118628926,0.822136960531984,0.0055457738057274,0.0055457738057274,-1.0312980850577906
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00767358537807448,0.00233215653996207,0.0713684727707158,0.307444763898641,0.0172788380976704,0.00511228295653041,0.588789900358405,0.0063917829512014,0.0063917829512014,-1.0300906311016962
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.579236803961587,0.00833063062779389,0.00173987762429209,0.156651961849343,0.112205138324295,0.00895304009765426,0.00427289873828259,0.707846452738339,0.269390835357988,0.269390835357988,-0.6547291495189385
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0158311033527607,0.00109353847138243,0.0200990623529318,0.00589717673503959,0.00332080816189693,0.00297802720282806,0.95078028372316,0.0070114291767852,0.0070114291767852,-1.0292062502525494
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,1,0,1,0,0,0,0.0,5.0755487449389,0.0138253404297663,0.00670375922221507,0.064918033729737,0.0310082272870404,0.0307691214666871,0.0156091189056244,0.83716639895893,0.0111434256880136,0.0111434256880136,-1.023308919755896
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.402809173856411,0.0144051248882893,0.000525788660297221,0.125667067331117,0.214373546599095,0.00410880851120861,0.00177167337754258,0.639147990632451,0.176512628889736,0.176512628889736,-0.7872881867764152
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.16930088,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,TZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,5.001930853466109,0.00115119797114568,0.0003959818507672,0.0538124209539168,0.93604524664705,0.00736502972190904,0.00123012285521143,0.0,0.0261518819859255,0.0261518819859255,-0.7291707023316024
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.0054786,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.579236803961587,0.0010942059599737,0.000714578151988552,0.367034511120116,0.62078160479883,0.0079478856978032,0.00242721427128835,0.0,0.970510173989973,0.970510173989973,1.7908416411254202
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,17.15847938,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,3F,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484131857611035,0.0376230130625874,0.00236009027623813,0.247039705692743,0.697452972603375,0.0104681865382628,0.00505603182679352,0.0,0.0013884403431976,0.0013884403431976,-0.7952517429011965
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.81395289,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PYR,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,5.0755487449389,0.00873826813676438,0.00145112475939544,0.193065080283125,0.778197018798523,0.014433213681334,0.00411529434085825,0.0,0.165721665234437,0.165721665234437,-0.35672988242469916
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.99522451,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.402809173856411,0.00532422079532615,0.00061084449763591,0.522469676271313,0.459778984209221,0.00966894873803684,0.00214732548846694,0.0,0.161020662402855,0.161020662402855,-0.3692744698577941
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.584763376210429,0.0318391346416656,0.000341552225113717,0.113678281409446,0.242279767731552,0.00387550619454475,0.000871625110337537,0.60711413268734,0.649833386251602,0.649833386251602,-0.11174818341388475
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.746322465743975,0.0548193142492001,0.000263362025026913,0.0902956804122817,0.160837629010128,0.00315355508353847,0.000739500993108033,0.689890958226717,1.16375238999006,1.16375238999006,0.6217350625958049
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,0,1,0,0,0.0,4.651385609785055,0.0172566765287249,0.00318344365411915,0.0712890876960715,0.171965068058214,0.0218135302099503,0.0115493777455846,0.702942816107335,0.00327405282427,0.00327405282427,-1.0345403650034368
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.584763376210429,0.000599963927151076,0.000397997752734626,0.420976508827142,0.560178394908249,0.017044159994242,0.000802974590480822,0.0,0.25255828640642,0.25255828640642,-0.1250070722684871
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.746322465743975,0.000524374578838527,0.00061514916196369,0.547432124587029,0.435435317287124,0.015309113403191,0.000683920981854007,0.0,0.568394489552276,0.568394489552276,0.7177992409467366
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O,DSPC,0,0,1,0,16.87346518,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,HIS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.651385609785055,0.00171983501988967,0.00189561016704693,0.0120716635806003,0.711278646835123,0.270438826106656,0.00259541829068387,0.0,0.0112897234542117,0.0112897234542117,-0.7688302502674332
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0047850951415261,0.000675911772575438,0.46069265034102,0.522359359837259,0.0109775121699624,0.00050947073765779,0.0,0.773205414607926,0.773205414607926,1.2643355117511204
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.633757642840004,0.00198911414189635,0.00126811595413123,0.543867583730296,0.438842770521552,0.0129988635137729,0.00103355213835123,0.0,1.98493053910539,1.98493053910539,4.497814051056962
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.609759638321899,0.00125031423153586,0.0004860362025215,0.538249539726811,0.445414640899446,0.0137801694455006,0.000819299494184621,0.0,0.291137444797345,0.291137444797345,-0.022058905064912687
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.392884144674663,0.00226285185388551,0.000562872305858137,0.731364439797527,0.256932619347553,0.00825451238600619,0.000622704309170273,0.0,1.82872279459479,1.82872279459479,4.080974968218046
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.36945365,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.484733632866144,0.0442923458834068,0.00055452650331333,0.106459881295074,0.192526940733964,0.00311682882196998,0.000623042068808978,0.652426434693463,0.672431538902446,0.672431538902446,-0.07949530652163618
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.35889865,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.633757642840004,0.0374610013402809,0.0005350551106764,0.260855439538844,0.469905543128085,0.00469334055693451,0.000912093945676405,0.225637526379503,1.69276100831231,1.69276100831231,1.3767547363410753
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.0333911,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,OZ,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.609759638321899,0.0836645231428707,0.000419599806684375,0.0235684307001288,0.0712275212970175,0.00119681308497475,0.00178295859414992,0.818140153374174,0.426058290183635,0.426058290183635,-0.431127857343191
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,16.68738808,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.392884144674663,0.0512990735432809,0.000672189655491244,0.187343972483681,0.232187436433234,0.00314791870850824,0.00146679734452725,0.523882611831278,1.30784095113947,1.30784095113947,0.8273833160675146
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O,DSPC,0,0,1,0,17.78759767,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,CYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.751259891859986,0.00405799702984203,0.00225047224182105,0.719270208750414,0.257208699720685,0.0138718178214465,0.00334080443579049,0.0,1.25160610942024,1.25160610942024,2.540943835364252
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.666265285347902,0.00272982965803786,0.000172365352517303,0.498048022051036,0.479137442306018,0.0180316959727267,0.00188064465966415,0.0,0.155537169131505,0.155537169131505,-0.3839071266005448
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.904756125442696,0.00273286200255075,0.00260055069792003,0.431146257918051,0.50349018951458,0.0550138028095967,0.00501633705730229,0.0,0.021985308799366,0.021985308799366,-0.7402891686477768
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.733211535868976,0.00166528576158017,0.000176886038620712,0.205207225042143,0.750916028545382,0.0392720451710516,0.00276252944122191,0.0,0.120096690961961,0.120096690961961,-0.478479751420455
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.858726543710496,0.00383743159330312,0.00248950729214128,0.555903422423481,0.380445635709031,0.0515668712566801,0.00575713172536402,0.0,0.0526538412251038,0.0526538412251038,-0.6584504418393717
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.31729774,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.666265285347902,0.0567289157085495,0.00653348267008008,0.064839577285576,0.335055277453961,0.0144955694225392,0.0143736618741762,0.507973515585118,0.268311366051918,0.268311366051918,-0.6562698060131026
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,18.71419039,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.904756125442696,0.0248552898268163,0.0125192728735768,0.0725307642598596,0.0355254691282667,0.0214395648154144,0.0248745799236939,0.808255059172372,0.0741845243461588,0.0741845243461588,-0.9333344503561898
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,19.34728513,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.733211535868976,0.0883917007893502,0.00174599838911923,0.0536405332414895,0.100118671210748,0.00771990063396103,0.00639776118235737,0.741985434552974,0.528035509086713,0.528035509086713,-0.28558239006925334
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,18.70678989,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intramuscular,0,1,0,0,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular,0,0,1,1,0,0,0,0.0,4.858726543710496,0.0175679405294797,0.00960173891174304,0.0903179131752613,0.0388184937379254,0.0182497546285787,0.0249045868533177,0.800539572163694,0.125181510399577,0.125181510399577,-0.8605497613389135
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O,DSPC,0,0,1,0,17.62870578,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,DOP,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.765586907393996,0.00159278655447388,0.00186611160196327,0.488795918944862,0.485247409700546,0.018616198181097,0.00388157501705755,0.0,0.352570746370957,0.352570746370957,0.14187535545424673
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O,DSPC,0,0,1,0,17.61880246,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PBA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,1,0,1,0,0,0,0.0,4.82374330878754,0.000875415234709484,0.00127375854285246,0.683377837104949,0.304003257921165,0.00820355561270421,0.00226617558361995,0.0,0.943420561172443,0.943420561172443,1.7185532318874628
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O,DSPC,0,0,1,0,16.58547122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.433313679041901,0.000602190120987361,0.000576528881915898,0.00566197423128506,0.0161763859347042,0.971683265119797,0.00529965571131053,0.0,0.0305789310371634,0.0305789310371634,-0.7173571583105779
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O,DSPC,0,0,1,0,17.70929826,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.356324137321509,0.00187378052819512,0.00157654975652554,0.0163863796216318,0.0648246159165097,0.905280007427939,0.0100586667491993,0.0,0.003875136361479,0.003875136361479,-0.7886160150068647
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O,DSPC,0,0,1,0,18.17273956,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.440767129696482,0.00301049906217731,9.21592223531261e-05,0.00380096827414773,0.0130323481002541,0.97657327492354,0.00349075041752818,0.0,0.0274401441027376,0.0274401441027376,-0.7257329854571254
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.349632566862877,0.00273989274094748,0.00161018393061426,0.0112824839963327,0.0583352940699212,0.919247401685963,0.00678474357622127,0.0,0.0081601896883771,0.0081601896883771,-0.7771813854096181
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,18.90345652,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.662778498608405,0.00349315451118928,0.00171298178399312,0.037797325974731,0.242816837972913,0.706569889763285,0.00760980999388795,0.0,0.0136767051395404,0.0136767051395404,-0.7624606092513427
O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,0,0,1,,4.405498990859024,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,GABA,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,,4.815106909815019,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.562053894914463,0.00241700650155169,0.00189161759954923,0.0117804592312353,0.0588098364115177,0.918016488291877,0.0070845919642692,0.0,0.288385322760908,0.288385322760908,-0.029402920107978105
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.89527599,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.667205576907544,0.00146771264056884,0.000853267380299107,0.00521853383313367,0.0984194458399351,0.890752405611161,0.00328863469490281,0.0,0.174730948641107,0.174730948641107,-0.3326886836733955
O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.94799221,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,1.0,4.701389043728634,0.00256320924432886,0.00193796271600952,0.0128146756680969,0.0418402586947232,0.934553052894321,0.00629084078252029,0.0,0.0492674291707299,0.0492674291707299,-0.6674870545840368
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.38469122,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.460491174618648,0.00101051612937229,0.00153512067382825,0.00950098551353592,0.161931963893941,0.822835993399315,0.00318542039000704,0.0,0.105055900803977,0.105055900803977,-0.5186159763833679
O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,19.0764718,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.505460341839079,0.00282763425766742,0.00135220428389579,0.101550310310828,0.701364372579719,0.18950529802972,0.00340018053817036,0.0,0.0700302222351868,0.0700302222351868,-0.6120817118766197
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,17.18453431,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.684905154006945,0.0025903109842197,0.00122267327648511,0.0959380417500791,0.558064631213231,0.339326541744348,0.00285780103163663,0.0,0.0836567108446898,0.0836567108446898,-0.5757195389760648
O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,18.58497913,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,1.0,4.695924549256556,0.00270162630925447,0.000571977156802491,0.072649821877092,0.283620916967858,0.638520904456637,0.00193475323235631,0.0,0.108372702997361,0.108372702997361,-0.5097651169808466
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O,DSPC,0,0,1,0,16.82518306,0.485,0.1,0.4,0.015,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,LYS,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,1,0,0,0,1,0,0,,4.202899968776446,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.52948326,0.4325,0.25,0.3,0.0175,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,5.029784112935016,0.000951862951033406,0.000642237882584555,0.00747953132811133,0.295137112679544,0.692754163229738,0.0030350919289883,0.0,0.19435393861906,0.19435393861906,-0.2803248961378029
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.10169345,0.3,0.25,0.425,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.833102254034098,0.00529626249319983,0.00246267213977097,0.0289260006923807,0.563065088278535,0.393847703229461,0.00640227316665243,0.0,0.049072760763369,0.049072760763369,-0.6680065256297026
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.72804315,0.38075000000000003,0.17975000000000002,0.41825,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,,4.93014804318357,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.39261658,0.37,0.25,0.37,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.146912912388804,0.000759366167023555,0.000694817987152034,0.00466364025695932,0.212680085653105,0.777593147751606,0.00360894218415418,0.0,0.201238755105862,0.201238755105862,-0.2619528199077537
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.51039532,0.385,0.205,0.385,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.684905154006945,0.00157535225652128,0.00592927130077556,0.00900517890128691,0.366135503933579,0.613833328839362,0.00352136476847493,0.0,0.149329656900936,0.149329656900936,-0.40047182198750214
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.48290639,0.45,0.09,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.869839484130799,0.00147117555088917,0.000927103843315829,0.00585237061645294,0.136146016514374,0.851575135737455,0.00402819773751327,0.0,0.31219703699332,0.31219703699332,0.034138443686487704
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.13138042,0.41200000000000003,0.2235,0.34325000000000006,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.901564199041894,0.00315707422768752,0.0025689389054212,0.0146712017391132,0.327849346901905,0.646061693847123,0.0056917443787501,0.0,0.158541375998041,0.158541375998041,-0.3758904252594646
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.11942242,0.41825,0.14975,0.41825,0.01375,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.039546637590676,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,14.79492927,0.45,0.225,0.3,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.9141243937154115,0.00113350028034128,0.000566939752127873,0.00680706926467914,0.502661298625749,0.486733894218144,0.00209729785895866,0.0,0.145448415448628,0.145448415448628,-0.4108288829150842
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,12.55393718,0.34325000000000006,0.21725000000000003,0.41825,0.02125,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,0,1,0,0.0,4.814620410170298,0.001692878443667,0.000820135726038303,0.00868136575507882,0.408928448915581,0.577101122031978,0.00277604912765729,0.0,0.113760366510672,0.113760366510672,-0.495388181160095
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.93959861,0.45,0.075,0.45,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.527640983478854,0.00506334343919377,0.004281344333051,0.0165771717732586,0.226890591170162,0.736348900590883,0.0108386486934518,0.0,0.0547343765642327,0.0547343765642327,-0.6528985503803821
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.59337013,0.45,0.1575,0.375,0.0175,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.810557015713042,0.00141112235558708,0.000749767156842064,0.00637541161251223,0.138880841494329,0.847648476304751,0.00493438107597822,0.0,0.294154433878409,0.294154433878409,-0.0140080944893819
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,11.66031337,0.3,0.24,0.45,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,5.167639042905921,0.00199236267032557,0.000827577235394216,0.008719084857644,0.192132365846187,0.792330257640873,0.0039983517495764,0.0,0.151793984465988,0.151793984465988,-0.3938957841268362
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,13.66358165,0.375,0.15,0.45,0.025,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,0.0,4.618086411254637,0.00271480786609193,0.00181664538344774,0.00938513027274936,0.132547184736695,0.849509595736892,0.0040266360041233,0.0,0.0950036114384557,0.0950036114384557,-0.5454404279666308
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.26186294,0.45,0.24,0.3,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,0,1,0,0,,5.098035484377089,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,,
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.27611859,0.45,0.11381999999999999,0.42618,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.680277658474897,0.00152924607683628,0.00192508702614222,0.0105762053188716,0.167270255683968,0.810875386281306,0.00782381961287527,0.0,0.278754923842637,0.278754923842637,-0.05510156049896443
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,16.11001923,0.45,0.13445000000000001,0.40445,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.000999438616070677,0.00125158481927741,0.00771842730472846,0.249469737208587,0.735450494958472,0.00511031709286499,0.0,0.286455906115286,0.286455906115286,-0.03455155257492116
O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O,DSPC,0,0,1,0,15.85662691,0.45,0.16405,0.37595,0.01,Pure,Microfluidic,mRNA,1,0,0,FFL,Mouse,0,0,0,0,0,0,0,1,0,body,1,0,0,0,0,0,0,0,0,intravenous,0,0,0,1,Individual,0,1,luminescence,,,,,,PRE,,,Chinese_Academy_of_Sciences,Chinese_Academy_of_Sciences,ccchina,,max,Chinese_Academy_of_Sciences,internal,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous,0,0,1,1,0,0,0,0.0,4.924350925499243,0.00141338619768439,0.00124322063420737,0.0100450891793794,0.235894751086175,0.745556785166654,0.00584676773589971,0.0,0.264336417833639,0.264336417833639,-0.09357722532293417

1 smiles Helper_lipid_ID Helper_lipid_ID_DOPE Helper_lipid_ID_DOTAP Helper_lipid_ID_DSPC Helper_lipid_ID_MDOA Cationic_Lipid_to_mRNA_weight_ratio Cationic_Lipid_Mol_Ratio Phospholipid_Mol_Ratio Cholesterol_Mol_Ratio PEG_Lipid_Mol_Ratio Purity Mix_type Cargo_type Cargo_type_mRNA Cargo_type_pDNA Cargo_type_siRNA Target_or_delivered_gene Model_type Model_type_A549 Model_type_BDMC Model_type_BMDM Model_type_HBEC_ALI Model_type_HEK293T Model_type_HeLa Model_type_IGROV1 Model_type_Mouse Model_type_RAW264p7 Delivery_target Delivery_target_body Delivery_target_dendritic_cell Delivery_target_generic_cell Delivery_target_liver Delivery_target_lung Delivery_target_lung_epithelium Delivery_target_macrophage Delivery_target_muscle Delivery_target_spleen Route_of_administration Route_of_administration_in_vitro Route_of_administration_intramuscular Route_of_administration_intratracheal Route_of_administration_intravenous Batch_or_individual_or_barcoded Batch_or_individual_or_barcoded_Barcoded Batch_or_individual_or_barcoded_Individual Value_name Formulation_ID Cationic_Lipid_Mass_Ratio Phospholipid_Mass_Ratio Cholesterol_Mass_Ratio PEG_Lipid_Mass_Ratio Amine Tail Lipid_name Library_ID Experiment_ID Experimenter_ID Experiment_weight Goal screen_id Source Sample_weight Comment Amine_number Full_SMILES Amine_SMILES Tail_length Num_tails Ketone Isocyanide Is_cyclic Formulation Batch_or_individual Random_id 4CR_Lipid_name Aldehyde Carboxylic_acid Amine_name Tail_name Linker MolWt Tail_count Num tails Common_name Ester Disulfide Total_radiance Form_comment molecular_weight split_name_for_normalization Encapsulation_Efficiency_EE<50 Encapsulation_Efficiency_50<=EE<80 Encapsulation_Efficiency_80<EE<=100 PDI_0_0to0_2 PDI_0_2to0_3 PDI_0_3to0_4 PDI_0_4to0_5 toxic size Biodistribution_lymph_nodes Biodistribution_heart Biodistribution_liver Biodistribution_spleen Biodistribution_lung Biodistribution_kidney Biodistribution_muscle quantified_total_luminescence unnormalized_delivery quantified_delivery
2 O=C(CN(CCCCCCCCCCCC)CCCCCCCCCCCC)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.44559484 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 6.892641641172089 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
3 CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCCCC DSPC 0 0 1 0 15.24245185 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.345103280569283 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
4 O=C(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.2554924 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.310127759130018 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
5 O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O DSPC 0 0 1 0 16.95535314 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.35696520407851 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
6 O=C(CN(CCCCCCCCCC)CCCCCCCCCC)NCCCN(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.51030189 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.175309921045205 4.175309921045206 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
7 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.11860943 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.447697327163527 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
8 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 16.80841018 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.381651564343798 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
9 CCCCCCCCCCN([C@H](C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC DSPC 0 0 1 0 14.7769988 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.2503506625488185 4.250350662548819 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
10 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.33731463 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.386765389021055 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
11 O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.55151343 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.391729410135267 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
12 O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H](C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.85660447 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.114394528387108 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
13 O=C(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)NCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.63293083 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 5.272999558563747 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
14 O=C(CN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O DSPC 0 0 1 0 16.2856483 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.28978103552575 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
15 O=C(CN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)NCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.23582504 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.260615499364025 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
16 O=C(NCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)CN(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.75702627 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.9788005705762375 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
17 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC DSPC 0 0 1 0 16.47477668 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.68213122712422 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
18 CCCCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 19.33366115 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
19 CCCCCCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.98780245 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.947340443723942 4.9473404437239425 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
20 CCCCCCCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CO)=O)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.42695266 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.545101659521972 0.0 0.00318490682025255 0.0608074236431031 0.251089505980848 0.00892095913117615 0.00601048706680474 0.669986717357815 0.0815243428420059 0.0815243428420059 -0.9228588036953479
21 CCCCCCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)=O)CO)CCCCCCCCCCCCCC DSPC 0 0 1 0 16.68206611 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.844974178195408 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
22 O=C(NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)[C@H]([C@H](O)C)N(CCCCCCCCCCCC)CCCCCCCCCCCC DSPC 0 0 1 0 15.77114057 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence thr Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.331522502500113 4.331522502500114 0.0 0.0131160505661734 0.0817206877958181 0.209957462105326 0.0363069917919837 0.0161572104727098 0.642741597267989 0.0248953087459781 0.0248953087459781 -1.0036817494221935
23 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4135253017332525 0.0 0.00151329913495755 0.0471551068594211 0.0476760649180962 0.00182335320536251 0.00763287581452213 0.89419930006764 0.35502103370942 0.35502103370942 -0.5325147239258616
24 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.509649984130679 0.0 0.00235961766437825 0.513627015742916 0.0879412499947796 0.00175822838354556 0.00311254749811917 0.391201340716262 1.0 1.0 0.38802190219888055
25 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.496359280129911 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
26 CCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCC)CCCCCCCC)=O)CO)CCCCCCCC DSPC 0 0 1 0 14.13296737 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.170425586627436 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
27 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.445353484534206 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
28 CCCCCCCCCCN([C@H](C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)=O)CO)CCCCCCCCCC DSPC 0 0 1 0 15.1299087 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.166510173022286 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
29 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 17.04310679 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.673109168996284 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
30 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCC)=O)CCCCCCOC(CCCCC)=O)=O)CO)CCCCCCOC(CCCCC)=O)CCCCC DSPC 0 0 1 0 16.72728505 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.7572902340489245 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
31 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.332573750954351 0.0 0.000230328920605394 0.0259372790881254 0.0734981485145439 0.000576894596302152 0.000867946038939987 0.898889402841483 0.486446282346577 0.486446282346577 -0.34493999468492637
32 O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 18.33700102 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.332573750954351 0.0 0.00183814880222334 0.508470854676458 0.479298868566087 0.00664368457868438 0.00374844337654761 0.0 0.0806697533656258 0.0806697533656258 -0.5836902104683951
33 O=C(CCN(CCCNC([C@@H](NCCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 14.7050121 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.577079305821566 0.0 0.00446051681777838 0.0286140231457339 0.01484311836534 0.00629790100652696 0.01599114503205 0.929793295632571 0.0275210452544693 0.0275210452544693 -0.9999342060867568
34 OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O DSPC 0 0 1 0 14.7050121 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.577079305821566 0.0 0.0104002218216073 0.139229779861971 0.807246421461676 0.041233674188 0.00188990266674509 0.0 0.0040656278842911 0.0040656278842911 -0.7881076899433005
35 O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.11494914 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.7535901911063645 0.0 0.00711911642710361 0.153280595121264 0.136743424441396 0.0628412485834964 0.0734141937722642 0.566601421654476 0.0027486514420013 0.0027486514420013 -1.0352902363032352
36 O=C(CCN([C@H](C(NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.11494914 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.7535901911063645 0.0 0.106975953776871 0.247623902989694 0.292657465739291 0.229416263063982 0.123326414430162 0.0 0.001042320755636 0.001042320755636 -0.7961753601769197
37 O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC DSPC 0 0 1 0 14.05354178 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.789157022101107 0.0 0.0386975655052687 0.153034034478582 0.0799184464451532 0.0414429326981307 0.0607210626185958 0.626185958254269 0.0073827728841294 0.0073827728841294 -1.0286762554754216
38 O=C(CN(CC(O)CCCCCC)CC(O)CCCCCC)NCCCN(CC(O)CCCCCC)CC(O)CCCCCC DSPC 0 0 1 0 14.05354178 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 1 0 0 0 0.0 4.639571612705423 0.0 0.135531713474282 0.541180183023036 0.178510571158094 0.0949195329757021 0.0498579993688861 0.0 0.004009461265808 0.004009461265808 -0.7882575701032632
39 O=C(CN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 15.91058453 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.639571612705423 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
40 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.391357962102766 0.0 0.000231298468169262 0.195828728849491 0.0126185833117857 0.000504922171493209 0.00109315352063243 0.789723313678428 1.0 1.0 0.38802190219888055
41 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.391357962102766 0.0 0.00515447939315304 0.962574355010024 0.0304157301451643 0.000918038843316605 0.000937396608342438 0.0 1.0 1.0 1.8695349995476385
42 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.45295097301058 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
43 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 4.45295097301058 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
44 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.508769411701737 0.0963955724315343 0.000259669027359828 0.0209585518067849 0.0324510369422159 0.00191021824445882 0.00526970020363582 0.84275525134401 0.95415067884307 0.95415067884307 0.32258414125816925
45 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.508769411701737 0.0 0.00301852406237983 0.561715155652109 0.427466534539213 0.00675382930885143 0.00104595643744612 0.0 0.469108231863161 0.469108231863161 0.4528546780295592
46 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.424367475163407 0.00431198097235812 0.000818950238891083 0.0696322838846972 0.0220758004851341 0.00177157151502323 0.00255208415951453 0.898837328744382 0.673380628639453 0.673380628639453 -0.07814073232611048
47 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCC)=O)CCCCCCCC DSPC 0 0 1 0 17.61200662 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.424367475163407 0.0 0.00336772556852765 0.856457049453334 0.133858740361315 0.00483749939645135 0.00147898522037143 0.0 0.274077344076178 0.274077344076178 -0.06758364367522034
48 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.570475216191205 0.0465123735855303 0.000498926332937811 0.165458883776434 0.0565565738614754 0.00106294680997165 0.00247840641808945 0.727431889215561 1.0 1.0 0.38802190219888055
49 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.570475216191205 0.0 0.00167236193574396 0.848665421605967 0.144098339320739 0.00370843762360476 0.00185543951394526 0.0 1.0 1.0 1.8695349995476385
50 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.570268133978827 0.0297656858896609 0.000244336475601744 0.00951547807887942 0.00817695885320599 0.000472306069630483 0.00458791238707824 0.947237322245943 0.549425262386022 0.549425262386022 -0.2550541831588352
51 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.570268133978827 0.0 0.00411439872497652 0.670601694270008 0.311096989874152 0.00850379747404768 0.00568311965681539 0.0 0.0620258136097327 0.0620258136097327 -0.6334414105302022
52 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCC)=O)CCCCCCC DSPC 0 0 1 0 17.33731463 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
53 O=C(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CO)CCCCCCOC(CCCCCC)=O)CCCCCC DSPC 0 0 1 0 17.04310679 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.311727053457954 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
54 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.9082333604781745 0.00523681863830338 0.000823668079767528 0.00977318183991921 0.0124596675509096 0.00267973433328739 0.00363617950788083 0.965390750049932 0.316498770359056 0.316498770359056 -0.5874950507095055
55 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.33700102 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.9082333604781745 0.0 0.010109099822305 0.45796731805265 0.507501663530466 0.0194068402228631 0.00501507837171616 0.0 0.0817828774610745 0.0817828774610745 -0.5807198479650095
56 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.590361070334383 0.00631834763893091 0.000504819647616299 0.140779687268235 0.0297514168337676 0.000617892126006545 0.0011394500617625 0.820888386423681 1.0 1.0 0.38802190219888055
57 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.590361070334383 0.0 0.00283873189227405 0.901276452952094 0.0938738308613158 0.00141019974741145 0.000600784546904834 0.0 1.0 1.0 1.8695349995476385
58 O=C(NCCCN(CCCCCCCCCC)CCCCCCCCCC)[C@H](C)N(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.63651378 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.442651256490317 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
59 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.97521151 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.530769863411841 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
60 O=C(NCCCCCCN(CCCCCCCCCC)CCCCCCCCCC)CN(CCCCCCCCCC)CCCCCCCCCC DSPC 0 0 1 0 14.88045619 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.48874872297084 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
61 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)CN(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.83327693 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.343844382133684 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
62 O=C(NCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.53889564 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.301494223781961 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
63 O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.27376909 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.596939379038152 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
64 O=C(CN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.27376909 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 5.596939379038152 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
65 O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC DSPC 0 0 1 0 15.06368788 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.403665809777363 0.0159262664008309 0.00726471746994425 0.0644691443511897 0.0154248397225439 0.00666778094817397 0.00618426236554005 0.884062988741777 0.163983867672707 0.163983867672707 -0.8051696746745034
66 O=C(CN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC DSPC 0 0 1 0 15.06368788 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.403665809777363 0.0 0.0110768066820314 0.679238145596264 0.289982439081482 0.0151104362851107 0.00459217235511197 0.0 0.0864824917721372 0.0864824917721372 -0.5681789657875123
67 O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC DSPC 0 0 1 0 15.91176651 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.285378059618076 0.00952025723585679 0.00424787112198889 0.0270494802958792 0.00951147065788185 0.00569809581675416 0.00864159943836194 0.935331225433277 0.22281247574214 0.22281247574214 -0.7212074197450102
68 O=C(CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC DSPC 0 0 1 0 15.91176651 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.285378059618076 0.0 0.00577401787332259 0.781123329740865 0.202386288853494 0.00852464019685452 0.00219172333546338 0.0 0.23688698835255 0.23688698835255 -0.16682580237138014
69 CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.11033537 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.0106352940962555 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
70 CCCCCCCCCCCCCCOC(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.11033537 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 5.0106352940962555 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
71 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.49121730591206 0.0307690543253117 0.000803846893528031 0.00327375890943859 0.00440309874760962 0.00131506681420977 0.00341198428561488 0.956023190024287 1.14370500641117 1.14370500641117 0.5931227328814345
72 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.49121730591206 0.0 0.0103006057269574 0.229208194092422 0.735779643429865 0.0182228400970524 0.00648871665370264 0.0 0.146101132843469 0.146101132843469 -0.40908711190961344
73 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.573885895948325 0.00305704097815131 0.00100491779320209 0.0165773259574103 0.0117710271412967 0.00208697129856503 0.00287252217431477 0.96263019465706 1.0 1.0 0.38802190219888055
74 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.573885895948325 0.0 0.00330040832612047 0.545398801975274 0.446192251044312 0.00323782528214899 0.00187071337214386 0.0 1.0 1.0 1.8695349995476385
75 O=C(CN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.79756457 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.789042318607025 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
76 CCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.40770989 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.168208681201016 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
77 CCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.93089479 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.697749367281184 4.697749367281185 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
78 O=C(CCN(CCCCCCNC([C@@H](N(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CO)=O)CCC(OCCCCCCCC)=O)OCCCCCCCC DSPC 0 0 1 0 16.38737682 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.2112383136936 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
79 CCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.61200662 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.27999390910873 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
80 O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.2554924 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.611152257665639 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
81 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.391561 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.1422481808981475 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
82 O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC DSPC 0 0 1 0 16.63400342 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.515354881665727 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
83 O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC DSPC 0 0 1 0 17.25637024 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.57532934397707 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
84 O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC DSPC 0 0 1 0 17.79833258 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.451896454476337 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
85 O=C(CN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)NCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.2554924 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.9250774057346085 4.925077405734609 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
86 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.391561 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.829912458665998 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
87 O=C(CN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC DSPC 0 0 1 0 16.63400342 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.421728001525434 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
88 O=C(CN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC DSPC 0 0 1 0 17.25637024 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.775756486563625 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
89 O=C(CN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC)NCCCN(CC(O)CCCCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCCCC DSPC 0 0 1 0 17.79833258 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 8.862341963516347 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
90 CCCCCCCCCCCCCCCCOC(CCN([C@H](C(NCCCCCCN(CCC(OCCCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCCCC)=O)=O)CO)CCC(OCCCCCCCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.55042057 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 5.550631295162026 5.5506312951620265 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
91 OC[C@@H](C(NCCCN(CC(CCCCCC)O)CC(CCCCCC)O)=O)N(CC(CCCCCC)O)CC(CCCCCC)O DSPC 0 0 1 0 14.34229222 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.47597224751641 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
92 CCCCCCCCC(CN(CCCNC([C@@H](N(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CO)=O)CC(CCCCCCCC)O)O DSPC 0 0 1 0 15.30473405 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.563722996073918 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
93 CCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCC)O)O DSPC 0 0 1 0 16.11614863 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.275554390163364 4.275554390163365 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
94 CCCCCCCCCCCCC(CN([C@H](C(NCCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CO)CC(CCCCCCCCCCCC)O)O DSPC 0 0 1 0 16.80938411 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.35709336812867 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
95 O=C(CCCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.32727581 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.473579765600494 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
96 O=C(CCCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)=O)CCCCCCOC(CCCCCCC)=O DSPC 0 0 1 0 17.03239796 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.5612182984589085 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
97 O=C(CCCCCC)OCCCCCCN(CCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.71577453 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.695924549256556 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
98 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCC)CC(O)CCCCCC)=O)N(CC(CCCCCC)O)CC(CCCCCC)O DSPC 0 0 1 0 14.72351388 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.857484114602081 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
99 CCCCCCCCC(CN([C@H](C(NCCCCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CO)CC(CCCCCCCC)O)O DSPC 0 0 1 0 15.6246954 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.483228515182849 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
100 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)=O)N(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O DSPC 0 0 1 0 16.38850868 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.426521874560432 4.426521874560433 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
101 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O DSPC 0 0 1 0 17.04402965 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.412919498116252 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
102 O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.53558149 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.69866052907543 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
103 O=C(CCCCCC)OCCCCCCN(CCCCCCNC([C@H](C)N(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.95535314 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.9459189793765646 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
104 O=C(NCCCCCCN(CCCCCCCC)CCCCCCCC)[C@H](C)N(CCCCCCCC)CCCCCCCC DSPC 0 0 1 0 13.97521151 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ala Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.450269224770129 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
105 O=C(CCCCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCCCC)=O)CCCCCCOC(CCCCCCCC)=O)=O)CCCCCCOC(CCCCCCCC)=O DSPC 0 0 1 0 17.46731585 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.659658371272161 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
106 O=C(CCCCCC)OCCCCCCN(CCCCCCNC(CN(CCCCCCOC(CCCCCC)=O)CCCCCCOC(CCCCCC)=O)=O)CCCCCCOC(CCCCCC)=O DSPC 0 0 1 0 16.8769168 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.139321635057579 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
107 O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O DSPC 0 0 1 0 18.04309994 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.283448621312786 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
108 O=C(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O DSPC 0 0 1 0 17.76093253 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence gly Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.1455128487965 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
109 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 18.07661492 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.3551691805039985 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
110 O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 18.15212729 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 6.632923618509176 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
111 O=C(C(CCCCCCCC)CCCCCC)OCCCCCC[N+](CC)(CC)CC.[Br-] DSPC 0 0 1 0 12.69438691 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence TEA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.762173934797756 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
112 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.240751047315928 0.0111914004572023 0.00227125491616379 0.00877931935589419 0.0082437061808303 0.00401873844514775 0.00849693826019724 0.956998642384564 0.596141429580998 0.596141429580998 -0.18837922911736
113 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.240751047315928 0.0 0.00531733106486159 0.69156525750989 0.28508003495893 0.0160312488066627 0.00200612765965623 0.0 0.176602424488684 0.176602424488684 -0.3276946657499996
114 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.253340627045836 0.0210584248832937 0.000931640117614886 0.0300315170504259 0.0160360600660287 0.002060495753182 0.00519348457253804 0.924688377556917 0.507741968135695 0.507741968135695 -0.31454604422779553
115 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.89554445 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.253340627045836 0.0 0.00533934786984105 0.597844801683409 0.374278985337898 0.0199301473078145 0.00260671780103763 0.0 0.177860137006811 0.177860137006811 -0.3243384702286213
116 O=C(NCCCCCCN([C@H](C(NCCCN(CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCNC(CCCCCCCCCCC)=O)=O)CO)CCCCCCNC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 18.15212729 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 8.664405571096625 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
117 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.498141613229568 0.00224222740615835 0.000962422246665562 0.00287219892799367 0.00322451176864607 0.00206661890626862 0.00333409585594076 0.985297924888327 0.792858557060483 0.792858557060483 0.0923823620278189
118 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.498141613229568 0.0 0.00657230701947091 0.556297397905001 0.404138164228711 0.0296624454205942 0.00332968542622302 0.0 0.20948041157182 0.20948041157182 -0.2399600273409918
119 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.462799844696364 4.462799844696365 0.0122002332749747 0.000591091003585345 0.00113975593374826 0.00176766182040017 0.00118628775621157 0.000814512180559894 0.98230045803052 1.58712844716331 1.58712844716331 1.2259922362734261
120 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.462799844696364 4.462799844696365 0.0 0.0055909076747788 0.864547542326111 0.121503978921508 0.00729914012568763 0.00105843095191469 0.0 0.762385942529413 0.762385942529413 1.2354638394013375
121 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.196600262926448 0.0390763854278316 0.00164994009844252 0.0661192424915616 0.0206209930549816 0.00197347693054232 0.00160454285244798 0.868955419144192 1.0 1.0 0.38802190219888055
122 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.196600262926448 0.0 0.00384316363496011 0.851255867494199 0.137210400166604 0.00701109092659647 0.000679477777641109 0.0 1.0 1.0 1.8695349995476385
123 O=C(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC DSPC 0 0 1 0 17.67788651 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.401951803481151 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
124 O=C(CCCCCCCCC)OCCCCCCN(CCCCCCOC(CCCCCCCCC)=O)CCCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC)=O)CCCCCCOC(CCCCCCCCC)=O)CO)=O DSPC 0 0 1 0 17.86915095 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.421487703554795 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
125 OC[C@@H](C(NCCCCCCN(CC(O)CCCCCCCCCCCCCC)CC(O)CCCCCCCCCCCCCC)=O)N(CC(CCCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCCC)O DSPC 0 0 1 0 17.61285873 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.577593418217857 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
126 OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCCC(OCCCCCCCCC)=O DSPC 0 0 1 0 15.66191374 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DBU Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.647271362006727 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
127 OC(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)(CC(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)C(NCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.541058240520847 0.0155523974922323 0.00129152518305059 0.446962380102849 0.0407067099579296 0.00170625578284345 0.00421830607343662 0.489562425407659 1.0 4.04718291807415 4.73706835052163
128 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.379899373657707 0.0165979002447495 0.00361970146585138 0.310566371988181 0.0118953898978584 0.00727497963461814 0.00647222326114303 0.643573433507598 1.0 1.0 0.38802190219888055
129 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.83323084 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.1751562049585145 0.127270779777207 0.0355651632001246 0.0965373529640882 0.0454740204097531 0.0338026797538366 0.0465840928565864 0.614765911038405 0.0505010966098528 0.0505010966098528 -0.9671362699547936
130 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.95682792 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.416186486320586 0.0275897803818406 0.0140220813902507 0.0611423332934752 0.0248626002542061 0.0133347505104052 0.0187510241318683 0.840297430037954 0.11103838626238 0.11103838626238 -0.8807353246775064
131 C=CCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)=O DSPC 0 0 1 0 18.01719192 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.445588116163626 0.0250376334304389 0.00337885545037859 0.0517009582142691 0.0430146012578083 0.00350252056656834 0.00406753936383155 0.869297891716705 0.594087846809013 0.594087846809013 -0.19131017455153912
132 CCCCCCCCCCCC(OCCCCCCN(CCCCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.28161356 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.381026134340298 0.00774884428490629 0.00205921183588078 0.0366644403250292 0.0113925424121347 0.00225130046176364 0.00414541402825956 0.935738246652026 0.903691788703443 0.903691788703443 0.2505674416217897
133 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.382151626862033 0.0281381236661192 0.00268792352252722 0.218417144486954 0.0369503427520482 0.00199553488006137 0.00289937744032574 0.708911553251965 1.0 1.0 0.38802190219888055
134 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.83044719 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.199605072879593 4.199605072879594 0.0747106900577881 0.0465999615731367 0.107994265529626 0.0501322770872438 0.0448116344718523 0.0485065251769853 0.627244646103368 0.0685266977729659 0.0685266977729659 -0.9414094990897005
135 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.94795095 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.333755086000182 0.0109650973341036 0.00500301836333305 0.0209516607489436 0.00928876974106986 0.00498354505150691 0.00613733877720584 0.942670569983837 0.624112412102086 0.624112412102086 -0.14845806079238213
136 CCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.64728116 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.3330989610504576 4.333098961050458 0.0312031939311219 0.00665572714585857 0.0303955096845431 0.016483404133503 0.00703656560389733 0.0108270584446455 0.897398541056431 0.396247798437663 0.396247798437663 -0.4736744378197291
137 O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 15.21401022 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 0.0 4.865224091322398 0.113993758795815 0.073640090558649 0.155999510493789 0.089181912745518 0.0778008933488344 0.0854800220277795 0.403903812029615 0.0331042054271613 0.0331042054271613 -0.991965723861604
138 O=C([C@H](CO)N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.964966 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.177279038170981 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
139 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.327834405590455 0.0791681309989092 0.00438236238399703 0.207450725009039 0.0200057324176319 0.00435501692886232 0.00687586277442937 0.677762169487131 1.0 1.0 0.38802190219888055
140 O=C(CN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.01143435 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.826712455935327 0.051854991416453 0.0528002488161413 0.131177333337399 0.0608349367134925 0.0676316423389937 0.091080124286102 0.544620723091419 0.0058976768275302 0.0058976768275302 -1.0307958367096368
141 O=C(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.98131005 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.613138355637268 0.0349404656939791 0.032170759570341 0.107989787547248 0.0410644871922655 0.0376181677387698 0.0487295770112475 0.697486755246149 0.0093821747742871 0.0093821747742871 -1.025822638898096
142 O=C([C@H](CO)N(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 13.72220648 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.45318382899021 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
143 O=C(CCCN(CCCCCCOC(CCCCCCC)=O)CCCCCCOC(CCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 14.27012616 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 5.256453162449338 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
144 O=C(CCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)N(CC1)CCN1C2=NC=CC=N2 DSPC 0 0 1 0 15.19898065 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence pp Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.868303385518459 4.86830338551846 0.0353281775739917 0.00307182736960491 0.034716407488313 0.0124183147896963 0.00493000176115631 0.00714349716206655 0.902391773855171 0.291015633780908 0.291015633780908 -0.6238654779555869
145 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.260282639765531 0.0263012913083446 0.00104221918552839 0.17396331575752 0.0231252484593015 0.00218421226891195 0.00250493797184971 0.770878775048544 1.0 1.0 0.38802190219888055
146 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.400848388914469 0.142104027989206 0.00287714799265922 0.215134204863943 0.0243152184566193 0.00619704480449007 0.00405451457231669 0.605317841320765 1.0 1.0 0.38802190219888055
147 CCCCCCCCCCCC(OCCCCCCN(CCN(C)CCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.06597416 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.3551691805039985 0.0696417285874694 0.0029599268608454 0.0569405498935433 0.0189535946790038 0.00628554949471398 0.00620455647115851 0.839014094013266 1.46543205325214 1.46543205325214 1.0523028700808776
148 O=C(OCCCCCCN([C@H](C(NCCN(C)CCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.80021894 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.3181545580794705 4.318154558079471 0.0260251149767627 0.00751090805185066 0.0532899531021804 0.0511794000344704 0.0152455710134586 0.0158624088727893 0.830886643948488 0.594741863231617 0.594741863231617 -0.19037673935045565
149 CCCCCCCCCCCC(OCCCCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)=O DSPC 0 0 1 0 17.89376817 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.605170185988091 4.605170185988092 0.00991904799330563 0.00800736011391533 0.0452217049389508 0.0197202047147262 0.0164331186633441 0.0158205463682553 0.884878017207502 0.0777961107519447 0.0777961107519447 -0.9281798674338029
150 O=C(OCCCCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCOC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.61561565 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.886582645426277 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
151 CCCCCCCCCCCC(OCCCCCCN(CCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.01340623 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.190175207928333 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
152 O=C(OCCCCCCN([C@H](C(NCCOCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.7439276 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.2694176902912275 0.0273933363293668 0.0025481137083807 0.0489889660247262 0.00910395259986531 0.00553863037137659 0.00570731639004281 0.900719684576242 0.282511511559215 0.282511511559215 -0.6360028597730629
153 O=C(CCCCCCCCCCC)OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)CCCCCCOC(CCCCCCCCCCC)=O DSPC 0 0 1 0 18.18802872 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.561949483533528 0.0107761878140537 0.0018907931479914 0.00906874325536026 0.00817364202148832 0.00369121050409089 0.00412231341943734 0.962277109837578 1.03869430459932 1.03869430459932 0.44324777229346224
154 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 17.8896653 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.422808628394115 0.0 0.00393259539867672 0.698404256940233 0.29082082024119 0.00482745799593445 0.00201486942396601 0.0 0.150267764477171 0.150267764477171 -0.3979684896277195
155 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 0 1 0 0 0.0 4.24735173134728 0.0 0.0193985055782088 0.642311593152982 0.297952931923085 0.0232690994142363 0.0170678699314884 0.0 0.0138284395356039 0.0138284395356039 -0.7620557072620823
156 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.776599301615622 0.0 0.00374237304524464 0.388696129733584 0.542462789676973 0.0600826887673663 0.00501601877683173 0.0 0.0757788640374704 0.0757788640374704 -0.5967415084575073
157 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.59784341060163 0.0 0.00454633850545055 0.547957057084188 0.42844914578143 0.0150324705651762 0.00401498806375593 0.0 0.0747683143174281 0.0747683143174281 -0.5994381520828621
158 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.37981918 46.5 0.465 7.5 0.075 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.784988612563927 4.784988612563928 0.0 0.00648649184357099 0.353238786148937 0.611732175774514 0.0204133713900616 0.00812917484291689 0.0 0.231046253558505 0.231046253558505 -0.18241175518238087
159 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.684905154006945 0.0 0.00209231248329155 0.858334702447977 0.133879376324869 0.0038743559198132 0.0018192528240494 0.0 1.0 1.0 1.8695349995476385
160 CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)C DSPC 0 0 1 0 18.00540724 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.583231278469337 4.583231278469338 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
161 CC(CNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)(CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)C DSPC 0 0 1 0 17.73535311 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.224056168743758 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
162 O=C(CCCCC(OCCCCCCN(CCCNC([C@@H](N(CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)CO)=O)CCCCCCOC(CCCCC(OCCCC(F)(F)F)=O)=O)=O)OCCCC(F)(F)F DSPC 0 0 1 0 18.72527826 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.972587226458725 4.972587226458726 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
163 O=C(OCCCCCCCCN(CCCNC([C@@H](N(CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCOC(CCCCCCCCC)=O)CO)=O)CCCCCCCCOC(CCCCCCCCC)=O)CCCCCCCCC DSPC 0 0 1 0 17.8896653 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.363226005210164 0.0302618004269707 0.0170318389360463 0.0852511261606349 0.0321310738618372 0.020553836096385 0.0249767617646758 0.78979356275345 0.103578477209434 0.103578477209434 -0.8913823687978608
164 O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCCCCCC DSPC 0 0 1 0 17.93964861 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.27430221608671 0.0441668582339066 0.00173504332049564 0.0552287456296669 0.0103338721124601 0.00424436496446174 0.00798306414101548 0.876308051597994 0.118006736161235 0.118006736161235 -0.8707898510406828
165 O=C(OCCCCCCN([C@H](C(NC/C=C/CN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCCCC=C DSPC 0 0 1 0 17.66483929 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.322011202263895 0.014374943627672 0.00199135248489222 0.0891563599260395 0.0109943655858212 0.00408170887074953 0.00721565797781185 0.872185611527014 0.120117219447052 0.120117219447052 -0.867777695195366
166 C=CCCCCCCCCC(OCCCCCCN(CCOCCOCCNC([C@@H](N(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)CO)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O DSPC 0 0 1 0 17.93091393 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.589955020181611 0.159505299591344 0.00863892692709962 0.059163494819016 0.0251436766117119 0.0207012928199433 0.0319161553971728 0.694931153833713 0.19624671777719 0.19624671777719 -0.7591230022455473
167 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.461068842013835 0.18227458966528 0.00260059752378256 0.10140002712747 0.0194272464327483 0.00394998811850684 0.00708234329707097 0.683265207835141 1.0 1.0 0.38802190219888055
168 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 18.16832078 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.897839799950911 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
169 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.87291972 32.96703297 0.3296703297 21.97802198 0.2197802198 43.95604396 0.4395604396 1.098901099 0.01098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.667205576907544 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
170 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.34369997 41.32231405 0.41322314050000003 16.52892562 0.16528925619999998 41.32231405 0.41322314050000003 0.826446281 0.00826446281 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.786658062033468 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
171 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.12329906 27.02702703 0.2702702703 32.43243243 0.32432432429999997 37.83783784 0.3783783784 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.520374534283375 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
172 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.602904588 25.0 0.25 40.0 0.4 30.0 0.3 5.0 0.05 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.2162671661789055 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
173 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.22342652 38.46153846 0.3846153846 21.97802198 0.2197802198 38.46153846 0.3846153846 1.098901099 0.01098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 4.634728988229636 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
174 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.21412129 40.0 0.4 34.28571429 0.3428571429 22.85714286 0.2285714286 2.857142857 0.028571428569999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.378896741664954 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
175 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.29890072 34.65346535 0.34653465349999996 39.6039604 0.396039604 24.75247525 0.2475247525 0.99009901 0.0099009901 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.661550519424199 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
176 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.62419529 41.86046512 0.4186046512 37.20930233 0.3720930233 18.60465116 0.1860465116 2.325581395 0.02325581395 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.552612935249416 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
177 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 5.021245473208271 0.0189024787568605 0.00542838949966448 0.0161874266221436 0.00564673685028802 0.0063903753402389 0.0111802988958026 0.936264294035002 0.0913658402077254 0.0913658402077254 -0.908812673116613
178 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.59373115 37.83783784 0.3783783784 37.83783784 0.3783783784 21.62162162 0.21621621619999998 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.484470400750307 0.220192249542946 0.000764987158036526 0.00117389921248248 0.000355328494502401 0.000727082388944626 0.00146163086877099 0.775324822334317 0.909323670538887 0.909323670538887 0.25860546111465654
179 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.02523135 35.8974359 0.35897435899999997 41.02564103 0.41025641030000004 20.51282051 0.20512820510000002 2.564102564 0.025641025640000002 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.474947598938117 0.0634606467339624 0.00208550415241484 0.000693953783467295 0.000703971489002912 0.00107462659382075 0.00306678394465369 0.928914513302678 0.68813569412733 0.68813569412733 -0.057081784806354334
180 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.01459482 54.90196078 0.5490196078 23.52941176 0.2352941176 19.60784314 0.1960784314 1.960784314 0.01960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.414493824811383 0.0115671522937999 0.000329262998462127 0.000782715410474643 0.000454168201139608 0.00050928396392566 0.0365052454816706 0.949852171650527 1.45919493888772 1.45919493888772 1.0434010414727322
181 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.50825332 52.83018868 0.5283018868 26.41509434 0.2641509434 18.86792453 0.1886792453 1.886792453 0.01886792453 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.573163389853005 0.0289504727873473 0.000587630380490671 0.00098172979734669 0.000247631664832521 0.000530890620697785 0.00148666967519347 0.967214975074092 1.18732779204068 1.18732779204068 0.6553827041429786
182 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.02959744 50.90909091 0.5090909091 29.09090909 0.2909090909 18.18181818 0.1818181818 1.818181818 0.01818181818 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.424367475163407 0.01918176556647 0.0010650954164724 0.0022206234626453 0.00126505200881015 0.0010329415925789 0.00258134917445057 0.972653172778573 0.519739549496667 0.519739549496667 -0.29742267487018065
183 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.0526464 43.24324324 0.43243243239999996 32.43243243 0.32432432429999997 21.62162162 0.21621621619999998 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.646312129319266 0.0173760673957131 0.000550323482827711 0.00231355504088989 0.000799250291024724 0.00171157517792979 0.00187915335599706 0.975370075255618 0.641975082983608 0.641975082983608 -0.12296382974571453
184 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.87880561 39.02439024 0.3902439024 39.02439024 0.3902439024 19.51219512 0.1951219512 2.43902439 0.0243902439 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.62790967295758 4.627909672957581 0.031425165165133 0.00121897501467252 0.00336392108926765 0.00273184674446895 0.00365496097119473 0.00253008289994281 0.95507504811532 0.292484943880311 0.292484943880311 -0.6217684269937327
185 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.72896002 41.02564103 0.41025641030000004 30.76923077 0.3076923077 25.64102564 0.2564102564 2.564102564 0.025641025640000002 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.6141299273595635 0.00243290161785256 0.00374029360494432 0.00771109158226845 0.00256075951190699 0.0024473081411263 0.00398520450059787 0.977122441041304 0.29000081469118 0.29000081469118 -0.6253138633910964
186 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.2936051730729785 0.0291199872991734 0.000702410023626044 0.0253755412996204 0.0176881988849176 0.000962484515645204 0.00126799370807735 0.92488338426894 1.0 1.0 0.38802190219888055
187 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.596835549198033 4.596835549198034 0.0642873127295256 0.000194616801396495 0.00548703707264694 0.0163820187916684 0.000849254927099769 0.000518055392084143 0.912281704285579 0.772854925639995 0.772854925639995 0.06383247693007311
188 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.26769266 37.83783784 0.3783783784 37.83783784 0.3783783784 21.62162162 0.21621621619999998 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.284827171296749 0.000820324065776298 6.77505055763446e-05 0.00130838737685328 0.00203458073148474 0.00044026025400656 0.00179231955954145 0.993536377506761 0.647354606156059 0.647354606156059 -0.11528598539707118
189 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 12.69845587 35.8974359 0.35897435899999997 41.02564103 0.41025641030000004 20.51282051 0.20512820510000002 2.564102564 0.025641025640000002 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.355939299910563 0.000606683031689403 0.000350488437662207 0.00200552330636915 0.00341592792036262 0.00135658595795651 0.00484812686613966 0.98741666447982 0.429472560198128 0.429472560198128 -0.42625489130230415
190 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.73864775 54.90196078 0.5490196078 23.52941176 0.2352941176 19.60784314 0.1960784314 1.960784314 0.01960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.210051369934071 0.0506054803736383 0.000934742670841204 0.00195746112246746 0.00131704918881155 0.00229254534633995 0.00362188526923176 0.93927083602867 0.295296757118666 0.295296757118666 -0.6177553084162161
191 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.22254695 52.83018868 0.5283018868 26.41509434 0.2641509434 18.86792453 0.1886792453 1.886792453 0.01886792453 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.19614876167715 0.000394517913167851 0.000925918583325644 0.00219111536287718 0.00192843383777798 0.00141208216065332 0.00279803133939282 0.990349900802805 0.423957111788814 0.423957111788814 -0.43412673292138043
192 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 16.73562869 50.90909091 0.5090909091 29.09090909 0.2909090909 18.18181818 0.1818181818 1.818181818 0.01818181818 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.324000197151533 0.0149763371723649 9.09516394922477e-05 0.00865819492777344 0.00337158611087041 0.000870833891384162 0.00234291805381448 0.9696891782043 0.799987755503576 0.799987755503576 0.10255740435442702
193 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.73441264 43.24324324 0.43243243239999996 32.43243243 0.32432432429999997 21.62162162 0.21621621619999998 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.638604962074329 0.00412763242238728 0.000587351434637121 0.00125519721482213 0.00156835329887146 0.00151910105091065 0.00332452673735467 0.987617837841017 0.519710678404319 0.519710678404319 -0.29746388070685387
194 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.55362203 39.02439024 0.3902439024 39.02439024 0.3902439024 19.51219512 0.1951219512 2.43902439 0.0243902439 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.465448242812954 0.001908149535057 0.00051106883667359 0.00195557181028906 0.00222543526142979 0.00102554934782431 0.0036709617373884 0.988703263471338 0.559906246507883 0.559906246507883 -0.24009535462913364
195 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.4082575 41.02564103 0.41025641030000004 30.76923077 0.3076923077 25.64102564 0.2564102564 2.564102564 0.025641025640000002 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.439351701293151 0.0164941051995163 0.00133624924425635 0.0136411729141475 0.0068725438331318 0.00281561744256348 0.00565863059250302 0.953181680773882 0.404416041627467 0.404416041627467 -0.4620164343493942
196 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.348211286179151 0.25310386523031 0.000588156076259717 0.140706646889545 0.17621759673582 0.00218337900345845 0.000839731767209391 0.426360624297398 1.0 1.0 0.38802190219888055
197 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 17.98993052 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.574298522321004 0.0173152888243317 0.00170643426094864 0.0181271736370668 0.0103847448319841 0.00234708518590686 0.00464250497463967 0.945476768285122 0.880302275630684 0.880302275630684 0.21718510735044552
198 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.54771521 32.96703297 0.3296703297 21.97802198 0.2197802198 43.95604396 0.4395604396 1.098901099 0.01098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.5300155123873305 4.530015512387331 0.0022188818222417 0.00151967168045253 0.0265741083102934 0.00935341146520975 0.00161955884356527 0.00594450434134348 0.952769863536894 0.693395601815244 0.693395601815244 -0.0495746598769834
199 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 16.03951812 41.32231405 0.41322314050000003 16.52892562 0.16528925619999998 41.32231405 0.41322314050000003 0.826446281 0.00826446281 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.640537329825382 0.0191565810814788 0.00120917820488213 0.00564887782228727 0.00368324602436162 0.00270413188019715 0.00625226385441887 0.961345721132374 0.702078866162311 0.702078866162311 -0.037181600128431615
200 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 10.8033785 27.02702703 0.2702702703 32.43243243 0.32432432429999997 37.83783784 0.3783783784 2.702702703 0.027027027029999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.2431955089544555 0.0191175904912105 0.0046774627841674 0.0253721583259607 0.0153479247605493 0.0105242912643767 0.0240873946993884 0.900873177674347 0.168910555827937 0.168910555827937 -0.7981381323616322
201 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 9.298704135 25.0 0.25 40.0 0.4 30.0 0.3 5.0 0.05 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.822697998516666 0.00783638212803346 0.00315432464612104 0.0156004284210389 0.0122536904537434 0.00649575798551451 0.014293561001533 0.940365855364016 0.26946434750834 0.26946434750834 -0.6546242303969191
202 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.90666525 38.46153846 0.3846153846 21.97802198 0.2197802198 38.46153846 0.3846153846 1.098901099 0.01098901099 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 5.291292751611072 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
203 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 13.89035919 40.0 0.4 34.28571429 0.3428571429 22.85714286 0.2285714286 2.857142857 0.028571428569999998 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.388753955423308 0.0457836478243602 0.00256820195313693 0.0933595380902435 0.040121791020458 0.00303459231576053 0.00719748271402532 0.807934746082015 0.638042293066864 0.638042293066864 -0.12857684559650717
204 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 12.97231927 34.65346535 0.34653465349999996 39.6039604 0.396039604 24.75247525 0.2475247525 0.99009901 0.0099009901 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.500031867864786 0.00367784574047392 0.00111977791364668 0.0109807451773001 0.00533981749985873 0.0035253353907892 0.00945759694134628 0.965898881336585 0.664597706735618 0.664597706735618 -0.09067602683869287
205 C=CCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCC=C)=O)CCCCCCOC(CCCCCCCCC=C)=O)=O)CO)CCCCCCOC(CCCCCCCCC=C)=O)=O DOPE 1 0 0 0 14.30278396 41.86046512 0.4186046512 37.20930233 0.3720930233 18.60465116 0.1860465116 2.325581395 0.02325581395 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.578518154990665 0.00602415700375336 0.00352191807012307 0.0129438874596237 0.0112365957475355 0.00705054455561779 0.0163551166761144 0.942867780487232 0.387412476367661 0.387412476367661 -0.486284519689253
206 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DOPE 1 0 0 0 14.78083639 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.373742415086184 0.00132025329631253 0.000860633620224201 0.00503931327076771 0.0029913613071963 0.00270028184029275 0.0088532339643477 0.978234922700859 1.0 1.0 0.38802190219888055
207 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.434619084793052 0.00770185399584477 0.00244833711322221 0.0462111239750686 0.0198642411939162 0.00381226904350308 0.00922041774380283 0.910741756934642 1.0 1.0 0.38802190219888055
208 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DSPC 0 0 1 0 11.7812451 54.90196078 0.5490196078 23.52941176 0.2352941176 19.60784314 0.1960784314 1.960784314 0.01960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.485936098064393 4.485936098064394 0.00448668985970796 0.00155299888410839 0.00808200908228358 0.00771278024096098 0.00385266053622471 0.00536687174407294 0.968945989652641 1.22295554827804 1.22295554827804 0.7062318887477964
209 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.01459482 54.90196078 0.5490196078 23.52941176 0.2352941176 19.60784314 0.1960784314 1.960784314 0.01960784314 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.73444252169223 0.00221922165343577 0.00134658478491355 0.00928071520245763 0.0103471897935628 0.00308928870366618 0.00305991935175966 0.970657080510204 2.4848301850992 2.4848301850992 2.507223675274371
210 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.67100244 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.379899373657707 0.0165979002447495 0.00361970146585138 0.310566371988181 0.0118953898978584 0.00727497963461814 0.00647222326114303 0.643573433507598 1.0 1.0 0.38802190219888055
211 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 18.26075368 50.0 0.5 10.0 0.1 38.5 0.385 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.7140245909001735 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
212 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.85564 30.9 0.309 36.3 0.363 25.9 0.259 6.9 0.069 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.002960000420248 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
213 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 12.10629825 33.7 0.337 32.2 0.322 28.8 0.28800000000000003 5.4 0.054000000000000006 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 3.9917579734469992 3.9917579734469997 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
214 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.076607527 21.5 0.215 44.3 0.44299999999999995 27.4 0.27399999999999997 6.7 0.067 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 4.150252194160396 4.150252194160397 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
215 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.262126773 28.5 0.285 36.9 0.369 23.3 0.233 11.4 0.114 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 3.938470175442994 3.9384701754429945 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
216 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.14390228 47.0 0.47 40.4 0.40399999999999997 5.7 0.057 6.8 0.068 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 4.139158578011893 4.139158578011894 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
217 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.465333240800292 0.0929588198875335 0.00109661539851913 0.0103406974639253 0.00262333547972377 0.00257373980843396 0.00319533888859958 0.887211453073265 2.49616154919077 2.49616154919077 2.5233961959539766
218 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.95064466 41.0 0.41 39.5 0.395 16.0 0.16 3.5 0.035 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.25063580654847 0.00217929592656579 0.00233573351378476 0.00718449647353577 0.00718369422949875 0.00471157922942054 0.00408542775852615 0.972319772868668 1.71461830076508 1.71461830076508 1.4079502315467747
219 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.40653622 31.3333 0.31333300000000003 31.3333 0.31333300000000003 31.3333 0.31333300000000003 6.0 0.06 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.188896879163323 0.0142737392382439 0.00348189340868737 0.00880858320276677 0.0038525568856599 0.00593274588142816 0.00610316587084082 0.957547315512373 0.645718762121967 0.645718762121967 -0.11762071943757772
220 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.77836699 50.0 0.5 23.5 0.235 23.5 0.235 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.343935283551159 0.0065593281978378 0.00138907609400551 0.00613919753007927 0.00613411120238244 0.00366825953495706 0.00406194129869205 0.972048086142046 1.35219591573978 1.35219591573978 0.890688278863242
221 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.200348974 22.0 0.22 22.0 0.22 50.0 0.5 6.0 0.06 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.057161771094385 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
222 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.72417162 27.0 0.27 27.0 0.27 41.0 0.41 5.0 0.05 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 0 1 0 0 4.102973888920155 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
223 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.092439729 16.0 0.16 39.5 0.395 41.0 0.41 3.5 0.035 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.127940511650616 0.0097349353786325 0.00823434520879355 0.0380775286515883 0.0189007253206434 0.0281939358827934 0.0273826912679074 0.869475838289641 0.161929321885153 0.161929321885153 -0.8081019945583146
224 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.93804335 39.5 0.395 16.0 0.16 41.0 0.41 3.5 0.035 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.116269119637892 0.00176070173692806 0.00134882241229812 0.00721447825021801 0.00277771416530431 0.00258248336542972 0.00338400053115958 0.980931799538662 0.834918279031508 0.834918279031508 0.15241147395626697
225 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.312676556539088 0.0122849683487715 0.00187692747865846 0.313004652084084 0.0267625511357853 0.00478000951875277 0.00400214034383056 0.637288751090117 1.0 1.0 0.38802190219888055
226 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.5612182984589085 0.00230427148121394 0.00151653786120671 0.00981883965091339 0.0195498469521307 0.00278714514326426 0.00256552165624032 0.961457837255031 3.54213716664653 3.54213716664653 4.0162493217529285
227 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 13.95064466 41.0 0.41 39.5 0.395 16.0 0.16 3.5 0.035 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.2756934238792645 0.00339636246099529 0.00439836397767252 0.00922438120812044 0.0070906355917358 0.00777777401057153 0.0070228258793507 0.961089656871554 1.60048193764837 1.60048193764837 1.2450508067393784
228 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.77836699 50.0 0.5 23.5 0.235 23.5 0.235 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.300138475201197 0.0251900613139205 0.0263858529561065 0.0690244086529141 0.0290319859464883 0.0512059292322219 0.0395084822769767 0.759653279621372 0.244442812501583 0.244442812501583 -0.6903358436733202
229 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.93804335 39.5 0.395 16.0 0.16 41.0 0.41 3.5 0.035 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.035478809355064 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
230 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.07835597 41.0 0.41 40.0 0.4 16.0 0.16 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.314416735011824 0.00832740543716945 0.00279899792781369 0.0133506530995165 0.00590470004845411 0.00800781451355169 0.00611088774111073 0.955499541232384 1.4036171732161 1.4036171732161 0.9640785029516001
231 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 12.46964291 32.3 0.32299999999999995 32.3 0.32299999999999995 32.3 0.32299999999999995 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.122932019074013 0.00935369123549862 0.00681432683334856 0.0266295187790274 0.0091342786879667 0.0148394527045059 0.0109795829907811 0.922249148768872 0.807897092094877 0.807897092094877 0.11384588723707807
232 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 0 1 0 0 0.0 4.214347354616797 0.00175971204953205 0.0023945553766021 0.00864096914216858 0.00287247113967731 0.00354165273920712 0.00438932700137801 0.976401312551435 2.1807873939408 2.1807873939408 2.073283128685432
233 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.297557478047431 0.0163588203416613 0.0050349858804786 0.141665503002976 0.0268932928836599 0.0108166459136593 0.00842178986187252 0.790808962115693 1.0 1.0 0.38802190219888055
234 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.623991940228679 0.0114998638575461 0.00130788860611426 0.00505223783079306 0.0046933168158669 0.00183202266239377 0.00287251942980201 0.972742150797484 1.19732008331576 1.19732008331576 0.6696440530835793
235 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.47398367 41.5 0.415 40.5 0.405 16.0 0.16 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.261975403606051 0.0120973279883405 0.00779128029381303 0.0260350268299895 0.0160802201335602 0.0156019499205845 0.0170739234476819 0.90532027138603 0.213285375768679 0.213285375768679 -0.7348048313269125
236 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.72570651 40.5 0.405 16.0 0.16 41.5 0.415 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.168678699274804 0.00644850088058007 0.00798921970887525 0.0221223520376599 0.0111631004951633 0.0106463671035197 0.00996963598739929 0.931660823786802 0.29077874869216 0.29077874869216 -0.6242035686713655
237 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.63764671 41.5 0.415 40.5 0.405 16.5 0.165 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.40562108352751 0.0088141667427258 0.00585903666298478 0.0157870816204507 0.010986042994209 0.00978368783097364 0.0102623946891479 0.938507589459508 0.370029347989408 0.370029347989408 -0.5110943308383519
238 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.402441819416474 0.154933534385178 0.00229861102597737 0.00525615721273492 0.00408539799683711 0.0022876287732977 0.00287249757879639 0.828266173027179 1.34933481107146 1.34933481107146 0.88660480982624
239 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.91076362 42.0 0.42 40.5 0.405 16.5 0.165 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.607168188650764 0.0408588610755303 0.0177373482989948 0.0425327283385076 0.0277718677406049 0.0276871974121274 0.0218927074965806 0.821519289637654 0.158736230637426 0.158736230637426 -0.8126592864976097
240 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.86872188 49.0 0.49 25.0 0.25 24.0 0.24 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.427716760590997 4.4277167605909975 0.00307921600642319 0.00224989559352084 0.00599370029233814 0.00443157985269048 0.00263031532778781 0.00293093049696406 0.978684362430275 1.27822314397057 1.27822314397057 0.785111741784596
241 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.444179499895966 0.0412236553892641 0.00390663231476925 0.121517080143859 0.0188177267921366 0.00482332620655526 0.0073631886059774 0.802348390547439 1.0 1.0 0.38802190219888055
242 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 17.98206341 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.573473099244836 4.573473099244837 0.00689869445402741 0.00600089779665737 0.0191135089301672 0.00620664286397134 0.00981653359048003 0.0097967903769499 0.942166931987747 0.749333285576466 0.749333285576466 0.030261566378477555
243 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.88644869 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.688591794127164 0.00886147101476089 0.00436553876298869 0.0150948084008648 0.00476112441477112 0.00826588994437132 0.00836456609804533 0.950286601364198 0.883781845590108 0.883781845590108 0.22215127176544153
244 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.877221176 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.829113417472866 0.00517423746484337 0.00420818785762778 0.0136338012801862 0.00389526355348657 0.0081026937251479 0.00825574629036951 0.956730069828339 1.02766134878372 1.02766134878372 0.4275011503825392
245 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 14.07835597 41.0 0.41 40.0 0.4 16.0 0.16 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4595662121293 0.025369932029363 0.00629969301959379 0.0185849502075566 0.00668329267445478 0.00984673129800659 0.00995848867776924 0.923256912093256 0.773367707896157 0.773367707896157 0.06456433777003012
246 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 9.306031912 41.0 0.41 40.0 0.4 16.0 0.16 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.528073135603124 0.00974026247143072 0.00459547921939943 0.0155882894773368 0.00424301614179951 0.00735125258984654 0.00918675243548622 0.949294947664701 0.925634770529548 0.925634770529548 0.28188523570969626
247 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 6.950074466 41.0 0.41 40.0 0.4 16.0 0.16 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.730921391293651 4.730921391293652 0.0307398296858454 0.00502448817507942 0.0144391987292623 0.00475975114719379 0.00732990645958348 0.00864531856689022 0.929061507236145 0.282355212986546 0.282355212986546 -0.6362259345836732
248 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.3578620076745835 0.0575651939642587 0.00224327504140443 0.293214190330324 0.103801109257072 0.00316596887134689 0.00243404296405076 0.537576219571543 1.0 1.0 0.38802190219888055
249 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.1515122352784415 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
250 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.0693509 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.2656332579940335 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
251 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.52014814 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.431173877940127 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
252 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.436396441739405 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
253 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.50369223 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.5666372362713075 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
254 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.844529643 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 4.765586907393996 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
255 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.23312059 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.149936935645806 0.0412282002133458 0.00282906106065428 0.0100452919302821 0.00294646346634102 0.0035555046437446 0.00510039590268196 0.93429508278295 2.31132936702855 2.31132936702855 2.259597216050143
256 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.0693509 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.244200317766478 0.0307672106546614 0.0492440442693678 0.143087600825361 0.0409904333145751 0.0410729694241231 0.0628737572688051 0.631963984243106 0.159668526820479 0.159668526820479 -0.8113286806519148
257 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.52014814 40.0 0.4 16.0 0.16 41.0 0.41 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.430459592195471 4.430459592195472 0.0144382835185698 0.030629687100469 0.0904231657039977 0.0327120644783899 0.0374915496460484 0.0408664371206098 0.753438812431916 0.342029093157046 0.342029093157046 -0.551057277633741
258 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 15.89020107 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.560277417097355 0.064087583051715 0.00731756531038673 0.0186036957891068 0.0053871458118381 0.00655845861152129 0.0086069303650773 0.889438621060355 2.14638048731397 2.14638048731397 2.024176383509215
259 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 10.50369223 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.667205576907544 0.00310349569550498 0.00416831577034203 0.0115025538737423 0.00349250282837259 0.00500126547712412 0.00690260249517487 0.965829263859739 3.35844880423818 3.35844880423818 3.754082841561727
260 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 7.844529643 40.5 0.405 16.5 0.165 41.5 0.415 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.713127327493184 0.00089376253365906 0.00183788568066981 0.0054363636464257 0.00195410248071216 0.00225811087193407 0.00383533887250888 0.98378443591409 3.24722414573894 3.24722414573894 3.595339103815341
261 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.359653205696989 0.0828383439279835 0.00565653685524585 0.157248489872984 0.00928479521934879 0.00688752099561758 0.00841921269728692 0.729665100431533 1.0 1.0 0.38802190219888055
262 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 16.86872188 49.0 0.49 25.0 0.25 24.0 0.24 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.634728988229636 0.00818072805535472 0.00273349879854757 0.0119346096951512 0.0075308964437597 0.00591367796700706 0.00578329104170321 0.957923297998477 0.213428398303373 0.213428398303373 -0.7346007045438266
263 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 11.15051107 49.0 0.49 25.0 0.25 24.0 0.24 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.7140245909001735 0.0160361616147136 0.00185083446366488 0.00730973501824061 0.00349956550575257 0.00416153151105757 0.00426975100661699 0.962872420879954 0.319359456002154 0.319359456002154 -0.5834121797200126
264 CCCCCCCCCCCC(OCCCCCCN([C@H](C(NCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)=O)CO)CCCCCCOC(CCCCCCCCCCC)=O)=O DOPE 1 0 0 0 8.327596879 49.0 0.49 25.0 0.25 24.0 0.24 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ser Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 0.0 4.822697998516666 0.0208671125611406 0.0200298903914976 0.0765668274895919 0.0297655881927753 0.0442427715485906 0.0417155046265625 0.766812305189841 0.0431568482237034 0.0431568482237034 -0.9776182391106099
265 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.548282323781043 0.235642631118293 0.00357683071882224 0.268183756367962 0.0537803810677977 0.0056567696761597 0.00550191880428196 0.427657712246684 1.0 1.0 0.38802190219888055
266 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.41834022 50.0 0.5 7.5 0.075 41.5 0.415 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.892602227184663 0.0004 0.0007 0.8627 0.1335 0.0019 0.0008 0.0 0.33 0.33 0.08164550420240263
267 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.34376213 50.0 0.5 29.0 0.29 20.0 0.2 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.935911747900319 0.0015 0.0017 0.585 0.3856 0.0215 0.0046 0.0 0.09 0.09 -0.5587925239809655
268 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.47881241 45.5 0.455 7.5 0.075 45.0 0.45 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.657762636107262 0.0008 0.0009 0.9399 0.0565 0.0012 0.0006 0.0 0.26 0.26 -0.10514892068441307
269 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.58994389 50.0 0.5 17.75 0.1775 30.25 0.3025 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.6520537718869415 0.0009 0.0008 0.8853 0.11 0.0021 0.0009 0.0 0.31 0.31 0.028275668520455245
270 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.356515817 38.0 0.38 30.0 0.3 30.0 0.3 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.522874943261261 0.0008 0.0012 0.7508 0.2416 0.0048 0.0008 0.0 0.12 0.12 -0.4787377704580445
271 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.211083767 38.0 0.38 16.0 0.16 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.802380355275797 0.0003 0.0007 0.8979 0.0985 0.0022 0.0005 0.0 0.45 0.45 0.40186451829408665
272 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.891852481 38.0 0.38 23.0 0.23 38.0 0.38 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.721173861744397 4.721173861744398 0.0003 0.0009 0.9061 0.0898 0.0024 0.0005 0.0 0.3 0.3 0.0015907506794815506
273 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.59856338 45.96 0.4596 24.83 0.2483 26.71 0.2671 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.599152113662528 0.0006 0.0011 0.8386 0.1563 0.0028 0.0007 0.0 0.36 0.36 0.16170025772532357
274 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.516252746 44.58 0.4458 19.33 0.19329999999999997 33.08 0.3308 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.539030383483546 4.539030383483547 0.0011 0.0009 0.9163 0.0784 0.0025 0.0008 0.0 0.24 0.24 -0.15851875636636045
275 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.79855736 50.0 0.5 7.5 0.075 39.5 0.395 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.602165676967792 0.0007 0.0007 0.9622 0.0349 0.001 0.0005 0.0 0.91 0.91 1.6293707389788754
276 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.789158454 42.5 0.425 30.0 0.3 24.5 0.245 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.506454213048934 0.0013 0.0022 0.7003 0.2848 0.009 0.0025 0.0 0.1 0.1 -0.5321076061399918
277 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.924427289 44.71 0.4471 13.58 0.1358 39.21 0.3921 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.543294782270004 0.0006 0.0008 0.9464 0.0496 0.0015 0.0011 0.0 0.56 0.56 0.6953986145447971
278 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.213203287 41.46 0.4146 24.83 0.2483 32.21 0.3221 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.600157644164547 0.0006 0.0011 0.9277 0.0684 0.0014 0.0008 0.0 0.44 0.44 0.37517960045311294
279 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.766920469 38.0 0.38 14.0 0.14 45.0 0.45 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.380775852772229 0.0005 0.001 0.9807 0.0157 0.0015 0.0006 0.0 0.46 0.46 0.42854943613506036
280 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.9150442 50.0 0.5 27.0 0.27 20.0 0.2 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.490881039585964 0.0013 0.001 0.7257 0.2649 0.0061 0.0009 0.0 0.13 0.13 -0.4520528526170708
281 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.33144164 47.24 0.47240000000000004 11.19 0.1119 38.87 0.3887 2.71 0.0271 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.62790967295758 4.627909672957581 0.0073 0.0639 0.7768 0.1461 0.0042 0.0016 0.0 1.3 1.3 2.670082534776849
282 OCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.92222847 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.8543712716215905 0.001 0.001 0.8647 0.1302 0.0025 0.0007 0.0 0.25 0.25 -0.13183383852538677
283 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.314817884980432 0.0009 0.0007 0.9116 0.0844 0.0018 0.0006 0.0 1.0 1.0 1.8695349995476385
284 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.42041204 49.0 0.49 7.5 0.075 41.5 0.415 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.534747721691545 4.534747721691546 0.0013 0.0021 0.5194 0.4632 0.0111 0.0029 0.0 0.5 0.5 0.535289107498955
285 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 15.70987342 34.25 0.3425 18.75 0.1875 45.0 0.45 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.19116874685764 4.191168746857641 0.0011 0.0011 0.7685 0.2222 0.0053 0.0018 0.0 0.15 0.15 -0.3986830169351235
286 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 11.2192693 22.0 0.22 30.0 0.3 45.0 0.45 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.151039905898646 0.0028 0.0014 0.4022 0.5806 0.0101 0.003 0.0 0.05 0.05 -0.6655321953448602
287 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.76101632 49.0 0.49 28.0 0.28 20.0 0.2 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.154184562578117 0.001 0.0012 0.5862 0.3912 0.0188 0.0017 0.0 0.16 0.16 -0.37199809909414977
288 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.31421044 44.61 0.4461 24.89 0.2489 27.94 0.27940000000000004 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.155753190350744 0.0041 0.0015 0.5886 0.3825 0.0211 0.0022 0.0 0.13 0.13 -0.4520528526170708
289 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 14.60470229 32.11 0.3211 24.89 0.2489 40.44 0.4044 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.104294893075268 4.104294893075269 0.0017 0.0016 0.5892 0.3913 0.0129 0.0033 0.0 0.05 0.05 -0.6655321953448602
290 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.00750041 49.0 0.49 18.75 0.1875 31.25 0.3125 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.516338972281476 0.0111 0.0048 0.1796 0.7293 0.0671 0.0082 0.0 0.14 0.14 -0.4253679347760971
291 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.77390107 42.13 0.4213 18.75 0.1875 38.13 0.38130000000000003 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.33204826486764 0.0167 0.0049 0.2598 0.6793 0.0289 0.0104 0.0 0.15 0.15 -0.3986830169351235
292 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.21646499 45.61 0.4561 13.64 0.1364 38.19 0.38189999999999996 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.365643155423357 0.0042 0.0015 0.3443 0.6172 0.0298 0.003 0.0 0.2 0.2 -0.2652584277302551
293 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.27353562 44.5 0.445 7.5 0.075 45.0 0.45 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.436751534363128 0.0067 0.0013 0.5909 0.385 0.0142 0.0019 0.0 0.22 0.22 -0.21188859204830776
294 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.27759176 49.0 0.49 30.0 0.3 20.0 0.2 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.151039905898646 0.0122 0.0028 0.2395 0.6818 0.0594 0.0044 0.0 0.08 0.08 -0.5854774418219391
295 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 14.75114553 34.5 0.345 30.0 0.3 32.5 0.325 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.2484952420493585 4.248495242049359 0.0029 0.0024 0.3338 0.6429 0.0151 0.0029 0.0 0.07 0.07 -0.6121623596629128
296 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 16.61008 39.36 0.3936 24.89 0.2489 34.19 0.3419 1.56 0.015600000000000001 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.384523514872469 0.0141 0.0106 0.3243 0.5845 0.0592 0.0073 0.0 0.14 0.14 -0.4253679347760971
297 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 12.46688772 24.0 0.24 30.0 0.3 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.796616650559046 4.796616650559047 0.0064 0.0026 0.3777 0.6006 0.0093 0.0034 0.0 0.1 0.1 -0.5321076061399918
298 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.37981918 46.5 0.465 7.5 0.075 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.516338972281476 0.0024 0.0028 0.4642 0.5174 0.0093 0.0039 0.0 0.81 0.81 1.362521560569139
299 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 16.04448224 37.36 0.3736 29.94 0.2994 31.71 0.3171 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.370712874773608 0.033 0.008 0.1094 0.8115 0.0325 0.0056 0.0 0.11 0.11 -0.5054226882990182
300 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.623010104116422 0.0087 0.0033 0.2348 0.7393 0.011 0.003 0.0 0.36 0.36 0.16170025772532357
301 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 14.343031 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.375757021660286 0.0019 0.0023 0.9077 0.0818 0.0033 0.003 0.0 1.0 1.0 1.8695349995476385
302 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.34776106 49.0 0.49 7.5 0.075 41.5 0.415 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.943782987108415 0.0542 0.0001 0.3146 0.0378 0.0014 0.0006 0.5913 1.14 1.14 0.5878348176473546
303 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.630330503 34.25 0.3425 18.75 0.1875 45.0 0.45 2.0 0.02 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.395682961121367 0.03 0.0006 0.0837 0.0261 0.002 0.0013 0.8563 0.78 0.78 0.07403017792270697
304 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 5.746375559 22.0 0.22 30.0 0.3 45.0 0.45 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.264087336809195 0.0156 0.0014 0.0138 0.0104 0.0025 0.0031 0.9532 0.32 0.32 -0.5824979728365652
305 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.15734025 49.0 0.49 28.0 0.28 20.0 0.2 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 1 0 0 1 0 0 0 4.513054897080286 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
306 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.812051718 44.61 0.4461 24.89 0.2489 27.94 0.27940000000000004 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.470495282661489 0.009 0.0004 0.0178 0.0948 0.0017 0.0003 0.8762 1.05 1.05 0.45938365771619283
307 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 7.893697629 32.11 0.3211 24.89 0.2489 40.44 0.4044 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.289088639014612 0.0343 0.0003 0.1697 0.027 0.0013 0.0009 0.7666 0.46 0.46 -0.38268505738809105
308 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.08675917 49.0 0.49 18.75 0.1875 31.25 0.3125 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.9684234452869465 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
309 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.13512977 42.13 0.4213 18.75 0.1875 38.13 0.38130000000000003 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.906015244966153 0.0128 0.0 0.028 0.0208 0.0006 0.0 0.9378 0.93 0.93 0.28811544447464355
310 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.43848511 45.61 0.4561 13.64 0.1364 38.19 0.38189999999999996 2.56 0.0256 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.525044141508806 4.525044141508807 0.0635 0.0002 0.2019 0.083 0.0009 0.0003 0.6502 1.5 1.5 1.1016394573720025
311 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.44748395 44.5 0.445 7.5 0.075 45.0 0.45 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.4520190064939165 0.011 0.0005 0.3972 0.0536 0.0016 0.0009 0.5352 1.45 1.45 1.0302777018546903
312 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 10.57169095 49.0 0.49 30.0 0.3 20.0 0.2 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.868303385518459 4.86830338551846 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
313 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 8.009941019 34.5 0.345 30.0 0.3 32.5 0.325 3.0 0.03 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.3476939555933765 0.0165 0.0 0.0427 0.0616 0.0035 0.0028 0.8728 0.42 0.42 -0.43977446180194085
314 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 9.301142352 39.36 0.3936 24.89 0.2489 34.19 0.3419 1.56 0.015600000000000001 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 4.629862798578463 0.0246 0.0 0.1245 0.0895 0.0015 0.0023 0.7576 0.44 0.44 -0.41122975959501595
315 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 6.525773643 24.0 0.24 30.0 0.3 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.732683506287051 0.006 0.0012 0.0205 0.0177 0.0008 0.0 0.9538 0.44 0.44 -0.41122975959501595
316 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.31765932 46.5 0.465 7.5 0.075 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.813809051099419 4.81380905109942 0.073 0.0 0.0373 0.0149 0.0 0.0 0.8748 1.01 1.01 0.40229425330234303
317 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.01888288 46.37 0.4637 7.5 0.075 44.21 0.4421 1.92 0.0192 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.706823839714591 0.0145 0.0004 0.1165 0.019 0.0007 0.0011 0.8477 1.94 1.94 1.7296229059243498
318 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 11.30562834 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.73795129722191 0.0343 0.0003 0.1697 0.027 0.0013 0.0009 0.7666 1.9 1.9 1.6725335015104998
319 O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCCCCC(OCCCCCCCCCCC)=O)CCO DSPC 0 0 1 0 9.480986593 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence Crtl Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.302712827954156 0.0455 0.0 0.324 0.073 0.0011 0.0012 0.5551 1.0 1.0 0.38802190219888055
320 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 17.88551615 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.763028270603671 0.0253701689981931 0.00985209592098701 0.307949537646453 0.622300893638244 0.0174680522283724 0.0170592515677505 0.0 0.0
321 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 17.94390528 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.584559232083967 0.00894763570081526 0.00182903773179144 0.430416319953847 0.549730482792046 0.00757886856613304 0.0014976552553668 0.0 0.0019532059842532 0.0019532059842532 -0.793744670428099
322 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 18.3291697 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.5827200571505 0.00757568328250189 0.00220510873539676 0.728025615125869 0.236446776884745 0.0226429923353559 0.00310382363613184 0.0 0.0011482099710543 0.0011482099710543 -0.7958927956755514
323 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 18.38109198 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.688867745009658 4.6888677450096585 0.00599960547383456 0.00187471922407934 0.58725363712808 0.393842224090862 0.00908706069367491 0.00194275338946932 0.0 0.0005585876781053 0.0005585876781053 -0.7974661979200065
324 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 19.03103458 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.374372415737022 0.0207124354254999 0.00767807173489595 0.560331852523788 0.3797189836544 0.0206003960524344 0.0109582606089812 0.0 0.0001489580680618 0.0001489580680618 -0.7985592911689305
325 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 19.07349618 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.567572155572773 0.0084525958204246 0.00170600389954699 0.807774257087237 0.172171860632781 0.00851123850670424 0.00138404405330582 0.0 0.0052460712339961 0.0052460712339961 -0.7849576865630203
326 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 17.88551615 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.763028270603671 0.0142965461163966 0.00273099369058116 0.2951874813445 0.196790510597468 0.00567584660232592 0.00900724719724339 0.476311374451485 0.0033203605888808 0.0033203605888808 -1.0344742729359027
327 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 17.94390528 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.584559232083967 0.0426258503334726 0.000887127042175757 0.102099604743599 0.057196348771858 0.00222434780081794 0.00162961025671667 0.79333711105136 0.0465195426566469 0.0465195426566469 -0.972818883550547
328 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 18.3291697 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.5827200571505 0.0182648912592805 0.000462867676668248 0.083073077462289 0.0429608616930204 0.00195825764287227 0.000923423624969053 0.852356620640901 0.0509209522037464 0.0509209522037464 -0.9665370373099135
329 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 18.38109198 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.688867745009658 4.6888677450096585 0.0068908069603713 0.000629547873998548 0.021394314943629 0.042448777163022 0.00198708372142952 0.00248444060475972 0.92416502873279 0.016201262972428 0.016201262972428 -1.0160901968011615
330 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCN1CCOCC1 DSPC 0 0 1 0 19.03103458 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.374372415737022 0.0116932676375475 0.00103739027764326 0.0525071135910941 0.0215477599193875 0.00368874758435242 0.00400972460855577 0.905515996381419 0.006104461793755 0.006104461793755 -1.0305007059455489
331 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCN1CCOCC1 DSPC 0 0 1 0 19.07349618 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ML Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.567572155572773 0.0237911981258413 0.00067207203055979 0.18334881014348 0.0466442684044473 0.00188246389345958 0.000953648344707904 0.742707539057504 0.0550488822731985 0.0550488822731985 -0.9606455105817374
332 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.82491214 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GLN Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.572543683160998 0.000714997259249526 0.000661552142657172 0.125943320778554 0.801966162874089 0.0693146503097598 0.00139931663568972 0.0 0.0127373438778132 0.0127373438778132 -0.764967287060561
333 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.91081918 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence BIM Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.358502089626924 0.00147233862420237 0.00107405472963131 0.901430168335102 0.0923159134092667 0.00310160866776492 0.000605916234032228 0.0 0.0763434621140544 0.0763434621140544 -0.5952348831288257
334 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81357262 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence 3FLA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.3962992939606 4.396299293960601 0.00110223184180453 0.00161797426133587 0.963322201717795 0.0321995776177804 0.00129202117564397 0.000465993385639812 0.0 0.380376087923258 0.380376087923258 0.21607368094058316
335 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.351438552905858 0.00061802522712851 0.00208191419961706 0.00520107649990865 0.018780252186508 0.966671145724669 0.00664758616216931 0.0 0.0289886812604962 0.0289886812604962 -0.7216007267742771
336 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2 DSPC 0 0 1 0 16.99522451 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence IZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.544995462952021 0.00423798522906651 0.00360605985882706 0.0132163308359338 0.182768863634774 0.789078621894797 0.00709213854660109 0.0 0.0033387326299993 0.0033387326299993 -0.7900474039572776
337 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.80884374 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PY Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.237000862623624 0.0123483310685072 0.00430719249252366 0.0429874465070588 0.751978605237179 0.174073814828135 0.0143046098665965 0.0 0.0005090956767902 0.0005090956767902 -0.7975982669188943
338 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.790487251761844 4.790487251761845 0.00153513483125764 0.00147931904743739 0.82338319944907 0.169033483447006 0.00378262362292623 0.000786239602302501 0.0 0.306009500746919 0.306009500746919 0.017627054049161966
339 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 17.10338647 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.842058839093973 0.00164287085070931 0.000659195379539964 0.94017588697419 0.0550751037989028 0.00183173459161262 0.000615208405045708 0.0 0.504231824712829 0.504231824712829 0.5465816969768794
340 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CCC(N)=O)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.82491214 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence GLN Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.572543683160998 0.0204881792124896 0.00996076677576078 0.024515683125648 0.0206076067733214 0.0213656753332114 0.0146396167476402 0.888422472031929 0.0035574041476412 0.0035574041476412 -1.0341359560461585
341 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C1=CC=CC2=C1N=CN2)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.91081918 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence BIM Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.358502089626924 0.0789442718629389 0.000859220559164078 0.352513414289749 0.0167725689541561 0.00207992092629201 0.000939235620822743 0.547891367786878 0.128034152082589 0.128034152082589 -0.8564783709716817
342 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(C(O)C(F)(F)F)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81357262 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence 3FLA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.3962992939606 4.396299293960601 0.020589791219893 0.00221295822133462 0.77006639472807 0.0336156368936998 0.00141982059640497 0.000804331444027444 0.17129106689657 0.352623838360951 0.352623838360951 -0.5359360852935553
343 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 1.0 4.351438552905858 0.0518701933925729 0.031230151711712 0.196119602463562 0.0891250765615729 0.225998436967717 0.183312147304902 0.222344391597961 0.0006916766953858 0.0006916766953858 -1.0382260228827003
344 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCN(CC1=CN=CN1)CC2=CN=CN2 DSPC 0 0 1 0 16.99522451 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence IZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.544995462952021 0.0318134391856252 0.0195739470918212 0.0658637908929555 0.0405146823853727 0.0383355214778253 0.0445803960220688 0.759318222944331 0.0007826107131428 0.0007826107131428 -1.0380962386598327
345 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCN1CCCC1)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.80884374 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PY Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.237000862623624 0.0496007240706346 0.0248050760368446 0.125156740550784 0.0913290655906173 0.0605654916232193 0.0647609529825488 0.583781949145352 0.000319594239126 0.000319594239126 -1.0387570720282182
346 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.790487251761844 4.790487251761845 0.0660465509749711 0.000704686244275338 0.176882938102508 0.134254150019803 0.00301700767902668 0.00146559050061717 0.617629076478799 0.391796497651864 0.391796497651864 -0.4800274905879333
347 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DOPE 1 0 0 0 17.10338647 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.842058839093973 0.180962520579808 0.000840183131263393 0.0600498448220066 0.0139903797423045 0.00230022430813273 0.00221494849849946 0.739641898917986 0.515169720881209 0.515169720881209 -0.3039448947184272
348 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.07758774 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.48897339158558 0.000136174132145422 0.00212452688507234 0.811633900204502 0.179761878637886 0.00385751556458306 0.00248600457581157 0.0 0.767759892635294 0.767759892635294 1.24980418110703
349 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.50454535 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence ALA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.675628649636653 0.00268100351583557 0.00240431632025112 0.142040711181502 0.523320437165769 0.324868931367264 0.00468460044937817 0.0 0.0241897161135915 0.0241897161135915 -0.7344067258409619
350 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.59671966 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence SER Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.737600973168581 0.00157432110064945 0.00176844882817444 0.053765469363115 0.438156626388713 0.500533090562106 0.00420204375724176 0.0 0.0189624719731265 0.0189624719731265 -0.7483555838832638
351 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCO)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.07758774 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OH Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.48897339158558 0.0550309639531662 0.00234353835896855 0.320198252727196 0.282656133384496 0.0064798077198827 0.00202476215621646 0.331266541700075 1.20135127285815 1.20135127285815 0.6753975083349388
352 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)C)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.50454535 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence ALA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.675628649636653 0.0418659426619505 0.0219153925677162 0.21668759621254 0.199875450362037 0.113029824089051 0.0495629458661235 0.357062848240582 0.0027707272238572 0.0027707272238572 -1.035258728972282
353 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC([C@@H](N)CO)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.59671966 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence SER Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.737600973168581 0.0234118812216689 0.0071462713755353 0.0426958781226752 0.0464078935005845 0.0346044033846598 0.0235967118628926 0.822136960531984 0.0055457738057274 0.0055457738057274 -1.0312980850577906
354 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.16930088 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence TZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 5.001930853466109 0.00767358537807448 0.00233215653996207 0.0713684727707158 0.307444763898641 0.0172788380976704 0.00511228295653041 0.588789900358405 0.0063917829512014 0.0063917829512014 -1.0300906311016962
355 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.579236803961587 0.00833063062779389 0.00173987762429209 0.156651961849343 0.112205138324295 0.00895304009765426 0.00427289873828259 0.707846452738339 0.269390835357988 0.269390835357988 -0.6547291495189385
356 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.15847938 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence 3F Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.484131857611035 0.0158311033527607 0.00109353847138243 0.0200990623529318 0.00589717673503959 0.00332080816189693 0.00297802720282806 0.95078028372316 0.0070114291767852 0.0070114291767852 -1.0292062502525494
357 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81395289 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PYR Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 1 0 1 0 0 0 0.0 5.0755487449389 0.0138253404297663 0.00670375922221507 0.064918033729737 0.0310082272870404 0.0307691214666871 0.0156091189056244 0.83716639895893 0.0111434256880136 0.0111434256880136 -1.023308919755896
358 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.99522451 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.40280917385641 4.402809173856411 0.0144051248882893 0.000525788660297221 0.125667067331117 0.214373546599095 0.00410880851120861 0.00177167337754258 0.639147990632451 0.176512628889736 0.176512628889736 -0.7872881867764152
359 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=NC=CS1)CC2=NC=CS2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.16930088 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence TZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 5.001930853466109 0.00115119797114568 0.0003959818507672 0.0538124209539168 0.93604524664705 0.00736502972190904 0.00123012285521143 0.0 0.0261518819859255 0.0261518819859255 -0.7291707023316024
360 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.0054786 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.579236803961587 0.0010942059599737 0.000714578151988552 0.367034511120116 0.62078160479883 0.0079478856978032 0.00242721427128835 0.0 0.970510173989973 0.970510173989973 1.7908416411254202
361 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CCC(F)(F)F)CCC(F)(F)F)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 17.15847938 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence 3F Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.484131857611035 0.0376230130625874 0.00236009027623813 0.247039705692743 0.697452972603375 0.0104681865382628 0.00505603182679352 0.0 0.0013884403431976 0.0013884403431976 -0.7952517429011965
362 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN1CC(C(OC)=O)CC1=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.81395289 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PYR Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 5.0755487449389 0.00873826813676438 0.00145112475939544 0.193065080283125 0.778197018798523 0.014433213681334 0.00411529434085825 0.0 0.165721665234437 0.165721665234437 -0.35672988242469916
363 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCN(CC1=CNN=C1)CC2=CNN=C2)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.99522451 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.40280917385641 4.402809173856411 0.00532422079532615 0.00061084449763591 0.522469676271313 0.459778984209221 0.00966894873803684 0.00214732548846694 0.0 0.161020662402855 0.161020662402855 -0.3692744698577941
364 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.584763376210429 0.0318391346416656 0.000341552225113717 0.113678281409446 0.242279767731552 0.00387550619454475 0.000871625110337537 0.60711413268734 0.649833386251602 0.649833386251602 -0.11174818341388475
365 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.746322465743975 0.0548193142492001 0.000263362025026913 0.0902956804122817 0.160837629010128 0.00315355508353847 0.000739500993108033 0.689890958226717 1.16375238999006 1.16375238999006 0.6217350625958049
366 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O DSPC 0 0 1 0 16.87346518 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence HIS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 0 1 0 0 0.0 4.651385609785054 4.651385609785055 0.0172566765287249 0.00318344365411915 0.0712890876960715 0.171965068058214 0.0218135302099503 0.0115493777455846 0.702942816107335 0.00327405282427 0.00327405282427 -1.0345403650034368
367 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.584763376210429 0.000599963927151076 0.000397997752734626 0.420976508827142 0.560178394908249 0.017044159994242 0.000802974590480822 0.0 0.25255828640642 0.25255828640642 -0.1250070722684871
368 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.746322465743975 0.000524374578838527 0.00061514916196369 0.547432124587029 0.435435317287124 0.015309113403191 0.000683920981854007 0.0 0.568394489552276 0.568394489552276 0.7177992409467366
369 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CC1=CN=CN1)=O DSPC 0 0 1 0 16.87346518 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence HIS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.651385609785054 4.651385609785055 0.00171983501988967 0.00189561016704693 0.0120716635806003 0.711278646835123 0.270438826106656 0.00259541829068387 0.0 0.0112897234542117 0.0112897234542117 -0.7688302502674332
370 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.484733632866144 0.0047850951415261 0.000675911772575438 0.46069265034102 0.522359359837259 0.0109775121699624 0.00050947073765779 0.0 0.773205414607926 0.773205414607926 1.2643355117511204
371 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.633757642840004 0.00198911414189635 0.00126811595413123 0.543867583730296 0.438842770521552 0.0129988635137729 0.00103355213835123 0.0 1.98493053910539 1.98493053910539 4.497814051056962
372 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.0333911 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.609759638321899 0.00125031423153586 0.0004860362025215 0.538249539726811 0.445414640899446 0.0137801694455006 0.000819299494184621 0.0 0.291137444797345 0.291137444797345 -0.022058905064912687
373 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 16.68738808 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.392884144674663 0.00226285185388551 0.000562872305858137 0.731364439797527 0.256932619347553 0.00825451238600619 0.000622704309170273 0.0 1.82872279459479 1.82872279459479 4.080974968218046
374 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.36945365 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.484733632866144 0.0442923458834068 0.00055452650331333 0.106459881295074 0.192526940733964 0.00311682882196998 0.000623042068808978 0.652426434693463 0.672431538902446 0.672431538902446 -0.07949530652163618
375 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.35889865 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.633757642840004 0.0374610013402809 0.0005350551106764 0.260855439538844 0.469905543128085 0.00469334055693451 0.000912093945676405 0.225637526379503 1.69276100831231 1.69276100831231 1.3767547363410753
376 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCN(CC1=COC=N1)CC2=COC=N2)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.0333911 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence OZ Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.609759638321899 0.0836645231428707 0.000419599806684375 0.0235684307001288 0.0712275212970175 0.00119681308497475 0.00178295859414992 0.818140153374174 0.426058290183635 0.426058290183635 -0.431127857343191
377 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 16.68738808 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.392884144674663 0.0512990735432809 0.000672189655491244 0.187343972483681 0.232187436433234 0.00314791870850824 0.00146679734452725 0.523882611831278 1.30784095113947 1.30784095113947 0.8273833160675146
378 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC([C@@H](N)CS)=O DSPC 0 0 1 0 17.78759767 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence CYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.751259891859986 0.00405799702984203 0.00225047224182105 0.719270208750414 0.257208699720685 0.0138718178214465 0.00334080443579049 0.0 1.25160610942024 1.25160610942024 2.540943835364252
379 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.31729774 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.666265285347902 0.00272982965803786 0.000172365352517303 0.498048022051036 0.479137442306018 0.0180316959727267 0.00188064465966415 0.0 0.155537169131505 0.155537169131505 -0.3839071266005448
380 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.71419039 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.904756125442696 0.00273286200255075 0.00260055069792003 0.431146257918051 0.50349018951458 0.0550138028095967 0.00501633705730229 0.0 0.021985308799366 0.021985308799366 -0.7402891686477768
381 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.733211535868975 4.733211535868976 0.00166528576158017 0.000176886038620712 0.205207225042143 0.750916028545382 0.0392720451710516 0.00276252944122191 0.0 0.120096690961961 0.120096690961961 -0.478479751420455
382 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 18.70678989 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.858726543710496 0.00383743159330312 0.00248950729214128 0.555903422423481 0.380445635709031 0.0515668712566801 0.00575713172536402 0.0 0.0526538412251038 0.0526538412251038 -0.6584504418393717
383 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.31729774 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.666265285347902 0.0567289157085495 0.00653348267008008 0.064839577285576 0.335055277453961 0.0144955694225392 0.0143736618741762 0.507973515585118 0.268311366051918 0.268311366051918 -0.6562698060131026
384 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 18.71419039 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.904756125442696 0.0248552898268163 0.0125192728735768 0.0725307642598596 0.0355254691282667 0.0214395648154144 0.0248745799236939 0.808255059172372 0.0741845243461588 0.0741845243461588 -0.9333344503561898
385 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 19.34728513 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.733211535868975 4.733211535868976 0.0883917007893502 0.00174599838911923 0.0536405332414895 0.100118671210748 0.00771990063396103 0.00639776118235737 0.741985434552974 0.528035509086713 0.528035509086713 -0.28558239006925334
386 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 18.70678989 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intramuscular 0 1 0 0 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intramuscular 0 0 1 1 0 0 0 0.0 4.858726543710496 0.0175679405294797 0.00960173891174304 0.0903179131752613 0.0388184937379254 0.0182497546285787 0.0249045868533177 0.800539572163694 0.125181510399577 0.125181510399577 -0.8605497613389135
387 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCCC1=CC=C(O)C(O)=C1)=O)=O DSPC 0 0 1 0 17.62870578 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence DOP Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.765586907393996 0.00159278655447388 0.00186611160196327 0.488795918944862 0.485247409700546 0.018616198181097 0.00388157501705755 0.0 0.352570746370957 0.352570746370957 0.14187535545424673
388 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCC(NCC1=CC=C(B(O)O)C=C1)=O)=O DSPC 0 0 1 0 17.61880246 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PBA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 1 0 1 0 0 0 0.0 4.82374330878754 0.000875415234709484 0.00127375854285246 0.683377837104949 0.304003257921165 0.00820355561270421 0.00226617558361995 0.0 0.943420561172443 0.943420561172443 1.7185532318874628
389 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O DSPC 0 0 1 0 16.58547122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.433313679041901 0.000602190120987361 0.000576528881915898 0.00566197423128506 0.0161763859347042 0.971683265119797 0.00529965571131053 0.0 0.0305789310371634 0.0305789310371634 -0.7173571583105779
390 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O DSPC 0 0 1 0 17.70929826 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.356324137321509 0.00187378052819512 0.00157654975652554 0.0163863796216318 0.0648246159165097 0.905280007427939 0.0100586667491993 0.0 0.003875136361479 0.003875136361479 -0.7886160150068647
391 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCNC(CCCN)=O)CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O DSPC 0 0 1 0 18.17273956 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.440767129696481 4.440767129696482 0.00301049906217731 9.21592223531261e-05 0.00380096827414773 0.0130323481002541 0.97657327492354 0.00349075041752818 0.0 0.0274401441027376 0.0274401441027376 -0.7257329854571254
392 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 18.38469122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.349632566862877 0.00273989274094748 0.00161018393061426 0.0112824839963327 0.0583352940699212 0.919247401685963 0.00678474357622127 0.0 0.0081601896883771 0.0081601896883771 -0.7771813854096181
393 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 18.90345652 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.662778498608405 0.00349315451118928 0.00171298178399312 0.037797325974731 0.242816837972913 0.706569889763285 0.00760980999388795 0.0 0.0136767051395404 0.0136767051395404 -0.7624606092513427
394 O=C(NCCN(CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCCN(CCCCCCOC(CCCCCCCCCCC)=O)CCCCCCOC(CCCCCCCCCCC)=O)CCCN DSPC 0 0 1 0 18.38469122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 0 0 1 4.405498990859024 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
395 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(CCCN)=O DSPC 0 0 1 0 16.89527599 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence GABA Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 4.815106909815019 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
396 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.89527599 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.562053894914463 0.00241700650155169 0.00189161759954923 0.0117804592312353 0.0588098364115177 0.918016488291877 0.0070845919642692 0.0 0.288385322760908 0.288385322760908 -0.029402920107978105
397 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.89527599 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.667205576907544 0.00146771264056884 0.000853267380299107 0.00521853383313367 0.0984194458399351 0.890752405611161 0.00328863469490281 0.0 0.174730948641107 0.174730948641107 -0.3326886836733955
398 O=C(OCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 17.94799221 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 1.0 4.701389043728634 0.00256320924432886 0.00193796271600952 0.0128146756680969 0.0418402586947232 0.934553052894321 0.00629084078252029 0.0 0.0492674291707299 0.0492674291707299 -0.6674870545840368
399 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 18.38469122 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.460491174618648 0.00101051612937229 0.00153512067382825 0.00950098551353592 0.161931963893941 0.822835993399315 0.00318542039000704 0.0 0.105055900803977 0.105055900803977 -0.5186159763833679
400 O=C(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 19.0764718 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.505460341839079 0.00282763425766742 0.00135220428389579 0.101550310310828 0.701364372579719 0.18950529802972 0.00340018053817036 0.0 0.0700302222351868 0.0700302222351868 -0.6120817118766197
401 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 17.18453431 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.684905154006945 0.0025903109842197 0.00122267327648511 0.0959380417500791 0.558064631213231 0.339326541744348 0.00285780103163663 0.0 0.0836567108446898 0.0836567108446898 -0.5757195389760648
402 O=C(OCCCCCCCCCCCCCC)CCN(CCC(OCCCCCCCCCCCCCC)=O)CCCCCCN(CCCCCCN(CCC(OCCCCCCCCCCCCCC)=O)CCC(OCCCCCCCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 18.58497913 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 1.0 4.695924549256556 0.00270162630925447 0.000571977156802491 0.072649821877092 0.283620916967858 0.638520904456637 0.00193475323235631 0.0 0.108372702997361 0.108372702997361 -0.5097651169808466
403 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC([C@@H](N)CCCCN)=O DSPC 0 0 1 0 16.82518306 48.5 0.485 10.0 0.1 40.0 0.4 1.5 0.015 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence LYS Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 1 0 0 0 1 0 0 4.202899968776446 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
404 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.52948326 43.25 0.4325 25.0 0.25 30.0 0.3 1.75 0.0175 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 5.029784112935016 0.000951862951033406 0.000642237882584555 0.00747953132811133 0.295137112679544 0.692754163229738 0.0030350919289883 0.0 0.19435393861906 0.19435393861906 -0.2803248961378029
405 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 11.10169345 30.0 0.3 25.0 0.25 42.5 0.425 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.833102254034098 0.00529626249319983 0.00246267213977097 0.0289260006923807 0.563065088278535 0.393847703229461 0.00640227316665243 0.0 0.049072760763369 0.049072760763369 -0.6680065256297026
406 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.72804315 38.075 0.38075000000000003 17.975 0.17975000000000002 41.825 0.41825 2.125 0.02125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 4.930148043183569 4.93014804318357 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
407 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.39261658 37.0 0.37 25.0 0.25 37.0 0.37 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 5.146912912388803 5.146912912388804 0.000759366167023555 0.000694817987152034 0.00466364025695932 0.212680085653105 0.777593147751606 0.00360894218415418 0.0 0.201238755105862 0.201238755105862 -0.2619528199077537
408 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.51039532 38.5 0.385 20.5 0.205 38.5 0.385 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.684905154006945 0.00157535225652128 0.00592927130077556 0.00900517890128691 0.366135503933579 0.613833328839362 0.00352136476847493 0.0 0.149329656900936 0.149329656900936 -0.40047182198750214
409 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.48290639 45.0 0.45 9.0 0.09 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.869839484130799 0.00147117555088917 0.000927103843315829 0.00585237061645294 0.136146016514374 0.851575135737455 0.00402819773751327 0.0 0.31219703699332 0.31219703699332 0.034138443686487704
410 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.13138042 41.2 0.41200000000000003 22.35 0.2235 34.325 0.34325000000000006 2.125 0.02125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 4.901564199041894 0.00315707422768752 0.0025689389054212 0.0146712017391132 0.327849346901905 0.646061693847123 0.0056917443787501 0.0 0.158541375998041 0.158541375998041 -0.3758904252594646
411 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.11942242 41.825 0.41825 14.975 0.14975 41.825 0.41825 1.375 0.01375 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 5.039546637590676 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
412 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 14.79492927 45.0 0.45 22.5 0.225 30.0 0.3 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.9141243937154115 0.00113350028034128 0.000566939752127873 0.00680706926467914 0.502661298625749 0.486733894218144 0.00209729785895866 0.0 0.145448415448628 0.145448415448628 -0.4108288829150842
413 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 12.55393718 34.325 0.34325000000000006 21.725 0.21725000000000003 41.825 0.41825 2.125 0.02125 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 0 1 0 0.0 4.814620410170298 0.001692878443667 0.000820135726038303 0.00868136575507882 0.408928448915581 0.577101122031978 0.00277604912765729 0.0 0.113760366510672 0.113760366510672 -0.495388181160095
414 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.93959861 45.0 0.45 7.5 0.075 45.0 0.45 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.527640983478854 0.00506334343919377 0.004281344333051 0.0165771717732586 0.226890591170162 0.736348900590883 0.0108386486934518 0.0 0.0547343765642327 0.0547343765642327 -0.6528985503803821
415 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.59337013 45.0 0.45 15.75 0.1575 37.5 0.375 1.75 0.0175 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.810557015713042 0.00141112235558708 0.000749767156842064 0.00637541161251223 0.138880841494329 0.847648476304751 0.00493438107597822 0.0 0.294154433878409 0.294154433878409 -0.0140080944893819
416 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 11.66031337 30.0 0.3 24.0 0.24 45.0 0.45 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 5.16763904290592 5.167639042905921 0.00199236267032557 0.000827577235394216 0.008719084857644 0.192132365846187 0.792330257640873 0.0039983517495764 0.0 0.151793984465988 0.151793984465988 -0.3938957841268362
417 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 13.66358165 37.5 0.375 15.0 0.15 45.0 0.45 2.5 0.025 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 0.0 4.618086411254637 0.00271480786609193 0.00181664538344774 0.00938513027274936 0.132547184736695 0.849509595736892 0.0040266360041233 0.0 0.0950036114384557 0.0950036114384557 -0.5454404279666308
418 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.26186294 45.0 0.45 24.0 0.24 30.0 0.3 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 0 1 0 0 5.098035484377089 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
419 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.27611859 45.0 0.45 11.382 0.11381999999999999 42.618 0.42618 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.680277658474896 4.680277658474897 0.00152924607683628 0.00192508702614222 0.0105762053188716 0.167270255683968 0.810875386281306 0.00782381961287527 0.0 0.278754923842637 0.278754923842637 -0.05510156049896443
420 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 16.11001923 45.0 0.45 13.445 0.13445000000000001 40.445 0.40445 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.924350925499243 0.000999438616070677 0.00125158481927741 0.00771842730472846 0.249469737208587 0.735450494958472 0.00511031709286499 0.0 0.286455906115286 0.286455906115286 -0.03455155257492116
421 O=C(OCCCCCCCC)CCN(CCC(OCCCCCCCC)=O)CCCCN(CCCCN(CCC(OCCCCCCCC)=O)CCC(OCCCCCCCC)=O)CCNC(C[C@@H](CN)CC(C)C)=O DSPC 0 0 1 0 15.85662691 45.0 0.45 16.405 0.16405 37.595 0.37595 1.0 0.01 Pure Microfluidic mRNA 1 0 0 FFL Mouse 0 0 0 0 0 0 0 1 0 body 1 0 0 0 0 0 0 0 0 intravenous 0 0 0 1 Individual 0 1 luminescence PRE Chinese_Academy_of_Sciences Chinese_Academy_of_Sciences ccchina max Chinese_Academy_of_Sciences internal Chinese_Academy_of_Sciences_Chinese_Academy_of_Sciences_body_Mouse_intravenous 0 0 1 1 0 0 0 0.0 4.924350925499243 0.00141338619768439 0.00124322063420737 0.0100450891793794 0.235894751086175 0.745556785166654 0.00584676773589971 0.0 0.264336417833639 0.264336417833639 -0.09357722532293417

2
docker-compose-gpu.yml
View File

@ -35,7 +35,7 @@ services:
target: streamlit
container_name: lnp-streamlit
ports:
- "18501:8501"
- "8501:8501"
environment:
- API_URL=http://api:8000
depends_on:

0
lnp_ml/interpretability/__init__.py
View File

438
lnp_ml/interpretability/token_importance.py
View File

@ -1,438 +0,0 @@
"""
Token-level feature importance for the LNP multi-task model.
Three complementary methods (inspired by AGILE / Captum):
1. Integrated Gradients — gradient-based attribution via Captum
2. Token Ablation — zero-out each token and measure prediction change
3. Fusion Attention Weights — extract learned attention pooling weights
Usage:
python -m lnp_ml.interpretability.token_importance \
--model-path models/model.pt \
--data-path data/processed/train.parquet \
--task delivery \
--method all
"""
from __future__ import annotations
import argparse
import os
from pathlib import Path
from typing import Dict, List, Optional, Tuple, Union
import numpy as np
import pandas as pd
import torch
import torch.nn as nn
from torch.utils.data import DataLoader
from loguru import logger
from tqdm import tqdm
from lnp_ml.config import MODELS_DIR, PROCESSED_DATA_DIR, REPORTS_DIR
from lnp_ml.dataset import LNPDataset, collate_fn
from lnp_ml.modeling.predict import load_model
from lnp_ml.modeling.models import LNPModel, LNPModelWithoutMPNN
TASKS = ["delivery", "size", "pdi", "ee", "biodist", "toxic"]
def get_token_names(model: Union[LNPModel, LNPModelWithoutMPNN]) -> List[str]:
if model.use_mpnn:
return ["mpnn", "morgan", "maccs", "desc", "comp", "phys", "help", "exp"]
return ["morgan", "maccs", "desc", "comp", "phys", "help", "exp"]
# ──────────────────────────────────────────────────────────────────────
# Helper: pre-compute projected tokens for the whole dataset
# ──────────────────────────────────────────────────────────────────────
@torch.no_grad()
def precompute_projected_tokens(
model: nn.Module,
loader: DataLoader,
device: torch.device,
) -> torch.Tensor:
"""
Run encoder + TokenProjector on all samples and stack results.
Returns:
all_tokens: [N, n_tokens, d_model]
"""
model.eval()
chunks = []
for batch in tqdm(loader, desc="Encoding tokens"):
smiles = batch["smiles"]
tabular = {k: v.to(device) for k, v in batch["tabular"].items()}
stacked = model._encode_and_project(smiles, tabular)
chunks.append(stacked.cpu())
return torch.cat(chunks, dim=0)
# ──────────────────────────────────────────────────────────────────────
# Method 1: Integrated Gradients (Captum)
# ──────────────────────────────────────────────────────────────────────
class _ProjectedWrapper(nn.Module):
"""Wraps model.forward_from_projected so Captum can attribute w.r.t. stacked tokens."""
def __init__(self, model: nn.Module, task: str) -> None:
super().__init__()
self.model = model
self.task = task
def forward(self, stacked: torch.Tensor) -> torch.Tensor:
"""
Args:
stacked: [B, n_tokens, d_model]
Returns:
[B] scalar predictions (sum over output dims for non-scalar heads)
"""
out = self.model.forward_from_projected(stacked, task=self.task)
if out.dim() > 1 and out.size(-1) > 1:
return out.sum(dim=-1)
return out.squeeze(-1)
def integrated_gradients_importance(
model: nn.Module,
all_tokens: torch.Tensor,
device: torch.device,
task: str = "delivery",
batch_size: int = 64,
n_steps: int = 50,
) -> np.ndarray:
"""
Compute token-level Integrated Gradients.
Returns:
importance: [n_tokens] averaged absolute attribution per token position
"""
from captum.attr import IntegratedGradients
wrapper = _ProjectedWrapper(model, task).to(device)
wrapper.eval()
ig = IntegratedGradients(wrapper)
N = all_tokens.size(0)
all_attrs: List[torch.Tensor] = []
for start in tqdm(range(0, N, batch_size), desc=f"IG ({task})"):
end = min(start + batch_size, N)
inp = all_tokens[start:end].to(device).requires_grad_(True)
baseline = torch.zeros_like(inp)
attr = ig.attribute(inp, baselines=baseline, n_steps=n_steps)
# attr: [B, n_tokens, d_model] → per-token L2 norm → [B, n_tokens]
token_attr = attr.detach().cpu().norm(dim=-1)
all_attrs.append(token_attr)
attrs = torch.cat(all_attrs, dim=0) # [N, n_tokens]
importance = attrs.mean(dim=0).numpy() # [n_tokens]
return importance
# ──────────────────────────────────────────────────────────────────────
# Method 2: Token Ablation (zero-out)
# ──────────────────────────────────────────────────────────────────────
@torch.no_grad()
def token_ablation_importance(
model: nn.Module,
all_tokens: torch.Tensor,
device: torch.device,
task: str = "delivery",
batch_size: int = 64,
) -> np.ndarray:
"""
For each token position, replace it with zeros and measure
the average absolute prediction change.
Returns:
importance: [n_tokens]
"""
model.eval()
n_tokens = all_tokens.size(1)
N = all_tokens.size(0)
# original predictions
orig_preds = _batch_predict(model, all_tokens, device, task, batch_size)
importance = np.zeros(n_tokens)
for t in range(n_tokens):
ablated = all_tokens.clone()
ablated[:, t, :] = 0.0
abl_preds = _batch_predict(model, ablated, device, task, batch_size)
importance[t] = np.abs(orig_preds - abl_preds).mean()
return importance
def _batch_predict(
model: nn.Module,
all_tokens: torch.Tensor,
device: torch.device,
task: str,
batch_size: int,
) -> np.ndarray:
"""Run forward_from_projected in batches, return [N] predictions."""
model.eval()
preds = []
N = all_tokens.size(0)
for start in range(0, N, batch_size):
end = min(start + batch_size, N)
inp = all_tokens[start:end].to(device)
out = model.forward_from_projected(inp, task=task)
if out.dim() > 1 and out.size(-1) > 1:
out = out.sum(dim=-1)
else:
out = out.squeeze(-1)
preds.append(out.cpu().numpy())
return np.concatenate(preds, axis=0)
# ──────────────────────────────────────────────────────────────────────
# Method 3: Fusion Attention Weights
# ──────────────────────────────────────────────────────────────────────
@torch.no_grad()
def fusion_attention_importance(
model: nn.Module,
all_tokens: torch.Tensor,
device: torch.device,
batch_size: int = 64,
) -> Optional[np.ndarray]:
"""
Extract FusionLayer attention weights (only works if strategy="attention").
Returns:
importance: [n_tokens] averaged attention weights, or None if not applicable.
"""
model.eval()
if model.fusion.strategy != "attention":
logger.warning("Fusion strategy is not 'attention'; skipping attention weight extraction.")
return None
N = all_tokens.size(0)
all_weights: List[torch.Tensor] = []
for start in range(0, N, batch_size):
end = min(start + batch_size, N)
inp = all_tokens[start:end].to(device)
attended = model.cross_attention(inp)
_, weights = model.fusion(attended, return_attn_weights=True)
all_weights.append(weights.cpu())
weights = torch.cat(all_weights, dim=0) # [N, n_tokens]
return weights.mean(dim=0).numpy()
# ──────────────────────────────────────────────────────────────────────
# Bonus: TokenProjector gate values (static)
# ──────────────────────────────────────────────────────────────────────
def gate_values(model: nn.Module) -> Dict[str, float]:
"""Read sigmoid(weight) from TokenProjector for each token."""
gates = {}
for key in model.token_projector.keys:
w = model.token_projector.weights[key].detach().cpu()
gates[key] = float(torch.sigmoid(w).item())
return gates
# ──────────────────────────────────────────────────────────────────────
# Visualization
# ──────────────────────────────────────────────────────────────────────
def normalize(arr: np.ndarray) -> np.ndarray:
s = arr.sum()
return arr / s if s > 0 else arr
def plot_token_importance(
results: Dict[str, np.ndarray],
token_names: List[str],
task: str,
out_dir: Path,
) -> Path:
import matplotlib
matplotlib.use("Agg")
import matplotlib.pyplot as plt
n_methods = len(results)
fig, axes = plt.subplots(1, n_methods, figsize=(6 * n_methods, max(4, len(token_names) * 0.6)))
if n_methods == 1:
axes = [axes]
channel_a_color = "#5a448e"
channel_b_color = "#e07b39"
for ax, (method_name, importance) in zip(axes, results.items()):
normed = normalize(importance)
order = np.argsort(normed)
names_sorted = [token_names[i] for i in order]
vals_sorted = normed[order]
n_tokens = len(token_names)
split_idx = 4 if n_tokens == 8 else 3
channel_a_set = set(token_names[:split_idx])
colors = [channel_a_color if n in channel_a_set else channel_b_color for n in names_sorted]
ax.barh(range(len(names_sorted)), vals_sorted, color=colors)
ax.set_yticks(range(len(names_sorted)))
ax.set_yticklabels(names_sorted, fontsize=11)
ax.set_xlabel("Normalized Importance", fontsize=11)
ax.set_title(f"{method_name}", fontsize=13)
ax.spines["top"].set_visible(False)
ax.spines["right"].set_visible(False)
fig.suptitle(f"Token Importance — task: {task}", fontsize=14, y=1.02)
fig.tight_layout()
out_dir.mkdir(parents=True, exist_ok=True)
fig_path = out_dir / f"token_importance_{task}.png"
fig.savefig(fig_path, dpi=200, bbox_inches="tight")
plt.close(fig)
logger.info(f"Figure saved to {fig_path}")
return fig_path
def save_csv(
results: Dict[str, np.ndarray],
token_names: List[str],
task: str,
out_dir: Path,
gate_vals: Optional[Dict[str, float]] = None,
) -> Path:
out_dir.mkdir(parents=True, exist_ok=True)
df = pd.DataFrame({"token": token_names})
for method_name, importance in results.items():
normed = normalize(importance)
df[f"{method_name}_raw"] = importance
df[f"{method_name}_normalized"] = normed
if gate_vals is not None:
df["gate_sigmoid"] = [gate_vals.get(t, float("nan")) for t in token_names]
df = df.sort_values(
by=[c for c in df.columns if c.endswith("_normalized")][-1],
ascending=False,
)
csv_path = out_dir / f"token_importance_{task}.csv"
df.to_csv(csv_path, index=False)
logger.info(f"CSV saved to {csv_path}")
return csv_path
# ──────────────────────────────────────────────────────────────────────
# Main
# ──────────────────────────────────────────────────────────────────────
def main() -> None:
parser = argparse.ArgumentParser(description="Token-level Feature Importance")
parser.add_argument("--model-path", type=str, default=str(MODELS_DIR / "model.pt"),
help="Path to trained model checkpoint")
parser.add_argument("--data-path", type=str, default=str(PROCESSED_DATA_DIR / "train.parquet"),
help="Path to data (parquet) for computing importance")
parser.add_argument("--task", type=str, default="delivery", choices=TASKS,
help="Target task for importance computation")
parser.add_argument("--method", type=str, default="ig",
choices=["ig", "ablation", "attention", "all"],
help="Which method(s) to run")
parser.add_argument("--batch-size", type=int, default=64)
parser.add_argument("--n-steps", type=int, default=50,
help="Number of interpolation steps for Integrated Gradients")
parser.add_argument("--device", type=str,
default="cuda" if torch.cuda.is_available() else "cpu")
parser.add_argument("--output-dir", type=str,
default=str(REPORTS_DIR / "feature_importance"))
args = parser.parse_args()
device = torch.device(args.device)
out_dir = Path(args.output_dir)
logger.info(f"Device: {device}")
logger.info(f"Model: {args.model_path}")
logger.info(f"Data: {args.data_path}")
logger.info(f"Task: {args.task}")
# ── Load model ──
model = load_model(Path(args.model_path), device)
token_names = get_token_names(model)
logger.info(f"Tokens ({len(token_names)}): {token_names}")
# ── Load data ──
df = pd.read_parquet(args.data_path)
dataset = LNPDataset(df)
loader = DataLoader(dataset, batch_size=args.batch_size, shuffle=False, collate_fn=collate_fn)
logger.info(f"Samples: {len(dataset)}")
# ── Pre-compute projected tokens ──
all_tokens = precompute_projected_tokens(model, loader, device)
logger.info(f"Projected tokens shape: {all_tokens.shape}")
# ── Gate values (always) ──
gv = gate_values(model)
logger.info(f"TokenProjector gate values: {gv}")
# ── Run selected methods ──
methods = (
["ig", "ablation", "attention"] if args.method == "all"
else [args.method]
)
results: Dict[str, np.ndarray] = {}
for method in methods:
logger.info(f"\n{'='*60}")
logger.info(f"Computing: {method}")
logger.info(f"{'='*60}")
if method == "ig":
imp = integrated_gradients_importance(
model, all_tokens, device,
task=args.task, batch_size=args.batch_size, n_steps=args.n_steps,
)
results["Integrated Gradients"] = imp
elif method == "ablation":
imp = token_ablation_importance(
model, all_tokens, device,
task=args.task, batch_size=args.batch_size,
)
results["Token Ablation"] = imp
elif method == "attention":
imp = fusion_attention_importance(
model, all_tokens, device,
batch_size=args.batch_size,
)
if imp is not None:
results["Fusion Attention"] = imp
# ── Print summary ──
logger.info(f"\n{'='*60}")
logger.info(f"Token Importance Summary (task={args.task})")
logger.info(f"{'='*60}")
for method_name, importance in results.items():
normed = normalize(importance)
order = np.argsort(-normed)
logger.info(f"\n {method_name}:")
for rank, idx in enumerate(order, 1):
logger.info(f" {rank:>2d}. {token_names[idx]:<10s} {normed[idx]:.4f}")
logger.info(f"\n Gate values (sigmoid):")
for name, val in sorted(gv.items(), key=lambda x: -x[1]):
logger.info(f" {name:<10s} {val:.4f}")
# ── Save results ──
if results:
plot_token_importance(results, token_names, args.task, out_dir)
save_csv(results, token_names, args.task, out_dir, gate_vals=gv)
logger.info("\nDone!")
if __name__ == "__main__":
main()

44
lnp_ml/modeling/layers/fusion.py
View File

@ -1,7 +1,7 @@
import torch
import torch.nn as nn
import torch.nn.functional as F
from typing import Dict, Literal, Tuple, Union
from typing import Dict, Literal, Union
PoolingStrategy = Literal["concat", "avg", "max", "attention"]
@ -48,64 +48,52 @@ class FusionLayer(nn.Module):
self.attn_query = nn.Parameter(torch.randn(1, 1, d_model))
self.attn_proj = nn.Linear(d_model, d_model)
def forward(
self,
x: Union[Dict[str, torch.Tensor], torch.Tensor],
return_attn_weights: bool = False,
) -> Union[torch.Tensor, Tuple[torch.Tensor, torch.Tensor]]:
def forward(self, x: Union[Dict[str, torch.Tensor], torch.Tensor]) -> torch.Tensor:
"""
Args:
x: Dict[str, Tensor] 每个 [B, d_model]，或已 stack 的 [B, n_tokens, d_model]
return_attn_weights: 若为 True 且策略为 attention，额外返回 attn_weights [B, n_tokens]
Returns:
return_attn_weights=False: [B, fusion_dim]
return_attn_weights=True: ([B, fusion_dim], [B, n_tokens])
[B, fusion_dim]
"""
# 如果输入是 dict，先 stack
if isinstance(x, dict):
x = torch.stack(list(x.values()), dim=1)
x = torch.stack(list(x.values()), dim=1) # [B, n_tokens, d_model]
if self.strategy == "concat":
out = x.flatten(start_dim=1)
return (out, None) if return_attn_weights else out
return x.flatten(start_dim=1) # [B, n_tokens * d_model]
elif self.strategy == "avg":
out = x.mean(dim=1)
return (out, None) if return_attn_weights else out
return x.mean(dim=1) # [B, d_model]
elif self.strategy == "max":
out = x.max(dim=1).values
return (out, None) if return_attn_weights else out
return x.max(dim=1).values # [B, d_model]
elif self.strategy == "attention":
return self._attention_pooling(x, return_attn_weights)
return self._attention_pooling(x)
else:
raise ValueError(f"Unknown strategy: {self.strategy}")
def _attention_pooling(
self, x: torch.Tensor, return_attn_weights: bool = False,
) -> Union[torch.Tensor, Tuple[torch.Tensor, torch.Tensor]]:
def _attention_pooling(self, x: torch.Tensor) -> torch.Tensor:
"""
Attention pooling: 用可学习 query 对 tokens 做加权求和
Args:
x: [B, n_tokens, d_model]
return_attn_weights: 是否返回权重
Returns:
return_attn_weights=False: [B, d_model]
return_attn_weights=True: ([B, d_model], [B, n_tokens])
[B, d_model]
"""
B = x.size(0)
# query: [1, 1, d_model] -> [B, 1, d_model]
query = self.attn_query.expand(B, -1, -1)
keys = self.attn_proj(x)
# Attention scores: [B, 1, n_tokens]
keys = self.attn_proj(x) # [B, n_tokens, d_model]
scores = torch.bmm(query, keys.transpose(1, 2)) / (self.d_model ** 0.5)
attn_weights = F.softmax(scores, dim=-1) # [B, 1, n_tokens]
out = torch.bmm(attn_weights, x).squeeze(1) # [B, d_model]
if return_attn_weights:
return out, attn_weights.squeeze(1) # [B, n_tokens]
# Weighted sum: [B, 1, d_model] -> [B, d_model]
out = torch.bmm(attn_weights, x).squeeze(1)
return out

32
lnp_ml/modeling/models.py
View File

@ -169,38 +169,6 @@ class LNPModel(nn.Module):
stacked = torch.stack([projected[k] for k in token_order], dim=1)
return stacked
def forward_from_projected(
self,
stacked: torch.Tensor,
task: Optional[str] = None,
) -> torch.Tensor:
"""
从已投影的 stacked tokens 开始 forward，用于 Captum 归因。
Args:
stacked: [B, n_tokens, d_model] TokenProjector 输出后 stack 的张量
task: 指定单任务名 ("size", "pdi", "ee", "delivery", "biodist", "toxic")。
若为 None，返回 delivery head 的标量输出。
Returns:
[B, 1] 或 [B, num_classes] 对应任务的预测输出
"""
attended = self.cross_attention(stacked)
fused = self.fusion(attended)
if task is None:
task = "delivery"
task_heads = {
"size": self.head.size_head,
"pdi": self.head.pdi_head,
"ee": self.head.ee_head,
"delivery": self.head.delivery_head,
"biodist": self.head.biodist_head,
"toxic": self.head.toxic_head,
}
return task_heads[task](fused)
def forward_backbone(
self,
smiles: List[str],

10
models/benchmark/config.json
View File

@ -5,14 +5,8 @@
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"use_mpnn": false,
"mpnn_ensemble_paths": null,
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,

68
models/benchmark/cv_results.json
View File

@ -1,68 +0,0 @@
{
"fold_results": [
{
"fold_idx": 0,
"best_val_loss": 0.866959414306682,
"best_val_rmse": 0.939569308267399,
"best_val_r2": 0.24210831047556391,
"epochs_trained": 21
},
{
"fold_idx": 1,
"best_val_loss": 0.7120698080343358,
"best_val_rmse": 0.89035723356781,
"best_val_r2": 0.1949605134929706,
"epochs_trained": 15
},
{
"fold_idx": 2,
"best_val_loss": 0.7995324550767853,
"best_val_rmse": 0.9427014903075246,
"best_val_r2": 0.14637384616637905,
"epochs_trained": 18
},
{
"fold_idx": 3,
"best_val_loss": 0.7464333962453039,
"best_val_rmse": 0.8886072948338112,
"best_val_r2": 0.16404373856430554,
"epochs_trained": 16
},
{
"fold_idx": 4,
"best_val_loss": 0.7502263283314047,
"best_val_rmse": 0.88562010695961,
"best_val_r2": 0.09823831053676024,
"epochs_trained": 11
}
],
"summary": {
"val_loss_mean": 0.7750442803989024,
"val_loss_std": 0.053755669741545144,
"val_rmse_mean": 0.9093710867872311,
"val_rmse_std": 0.0259985349306361,
"val_r2_mean": 0.16914494384719586,
"val_r2_std": 0.048088236270900114
},
"config": {
"d_model": 256,
"num_heads": 8,
"n_attn_layers": 4,
"fusion_strategy": "attention",
"head_hidden_dim": 128,
"dropout": 0.1,
"use_mpnn": true,
"mpnn_ensemble_paths": [
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_0/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_1/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_2/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_3/fold_0/model_0/model.pt",
"/home/ubuntu/projects/\u4e34\u65f6\u8dd1\u4e0b\u811a\u672c/EXP/lnp_ml/models/mpnn/all_amine_split_for_LiON/cv_4/fold_0/model_0/model.pt"
],
"lr": 0.0001,
"weight_decay": 1e-05,
"batch_size": 64,
"epochs": 50,
"patience": 10
}
}

170
models/benchmark/fold_0/history.json
View File

@ -1,170 +0,0 @@
[
{
"epoch": 1,
"train_loss": 0.7899117102249027,
"val_loss": 0.9106255005528325,
"val_rmse": 0.9542669915061958,
"val_r2": 0.218211451466231,
"lr": 0.0001
},
{
"epoch": 2,
"train_loss": 0.6509626604859896,
"val_loss": 0.904300603615648,
"val_rmse": 0.9509472242536414,
"val_r2": 0.22364146549089958,
"lr": 0.0001
},
{
"epoch": 3,
"train_loss": 0.5816657132710804,
"val_loss": 0.9535427025920375,
"val_rmse": 0.9764951165159946,
"val_r2": 0.18136623613531166,
"lr": 0.0001
},
{
"epoch": 4,
"train_loss": 0.5494824945224491,
"val_loss": 0.9088308029281216,
"val_rmse": 0.9533261696672906,
"val_r2": 0.219752238617257,
"lr": 0.0001
},
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